5-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Alberobello and Amalfi

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Escape the ordinary with this exciting 5-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 1 night in Alberobello, and 1 night in Amalfi. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Amalfi Coast and Archaeological Park Of Pompeii are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Sassi Di Matera, learn more about the unique Naples National Archaeological Museum, and immerse yourself in the vibrant atmosphere of Trulli Di Alberobello Puglia.

As you hit the open road and drive through Brindisi, Matera, Alberobello, Positano, Amalfi, Ravello, Pompei, and Naples, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Brindisi - Arrival day
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  • Lungomare Regina Margherita
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Bracerie Escosazio, a highly-rated dining destination in Brindisi. If you're eager to try something different, consider Penny, another top spot with a tantalizing menu. You might also want to secure a reservation at Piadineria. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Brindisi this evening.

Continue the enjoyment post-dinner at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Eden Cafè offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Altair Cafè. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Alberobello
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Drive 223 km, 3 hours 27 min

  • Palombaro lungo
  • Sassi di Matera
  • Belvedere di Piazza Giovanni Pascoli
  • Trulli di Alberobello Puglia
  • Territory Museum "House Pezzolla"
  • More

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Matera and Alberobello. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Alberobello. You will spend 1 night here for some well-deserved relaxation.

Start by visiting Palombaro Lungo, a prime spot to begin your journey. This instagrammable cave system is sure to impress. Next on your list is Sassi Di Matera, another must-visit landmark and well-known archeological site renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Brindisi by sampling some local delicacies. When you’re ready for more sightseeing, head to Belvedere Di Piazza Giovanni Pascoli. This romantic observation deck is an essential place to visit for anyone looking for the full Brindisi experience. We also recommend visiting Trulli Di Alberobello Puglia, a notable historical landmark. Nearby, you'll also find Territory Museum "house Pezzolla", ready to add charm to your journey.

At the end of the day, you will drive to Alberobello, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Alberobello's best restaurants.

Don’t miss out on dining at Ristorante "I Primi di Puglia" - Alberobello, a top-rated dining destination in Alberobello.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 3

Day 3

  • Alberobello
  • Amalfi
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Drive 385 km, 5 hours 52 min

  • Chiesa di Santa Maria Assunta
  • Spiaggia di Positano Marina Grande
  • Amalfi Coast
  • Villa Rufolo
  • More

Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Positano, Amalfi, and Ravello. At the end of the day, you will enjoy the comforts of a top-rated hotel in Amalfi, which will be your home away from home for 1 night.

Discover a day packed with fun adventures, romantic experiences, and scenic views in Alberobello. Begin your sightseeing with Chiesa Di Santa Maria Assunta. This often recommended church is one of the top attractions in the village. Proceed to Spiaggia Di Positano Marina Grande, another must-visit attraction.

As you wander through the inviting streets of Alberobello, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Amalfi Coast. This astonishing coast is a traveler-favorite. Not far away, you’ll find Villa Rufolo, another key site on your sightseeing itinerary.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Amalfi. Amalfi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Amalfi. If you are looking to dine at a popular restaurant in the village, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Pasticceria Pansa Amalfi, an iconic dining spot in Amalfi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Grand Hotel Excelsior Amalfi, a popular restaurant in Amalfi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Lido Azzurro, a hidden gem nestled in Amalfi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Bar Della Valle, which offers the perfect atmosphere for a night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Amalfi
  • Brindisi
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Drive 443 km, 5 hours 50 min

  • Archaeological Park of Pompeii
  • Naples National Archaeological Museum
  • Spaccanapoli
  • More

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pompei and Naples. In the evening, you’ll end up in Brindisi, where you will stay for 1 night.

Amalfi is brimming with adventures. Today’s wonderful stops include an archeological site, a museum, and a street. Begin your sightseeing adventure at the popular Archaeological Park Of Pompeii and allow yourself time to explore. Just a short distance away you'll find your next stop, Naples National Archaeological Museum, a detailed museum that draws visitors from far and near.

Continue your journey to Spaccanapoli, one of the town’s most beloved spots that you shouldn’t miss.

When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Brindisi. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a top-rated dining spot in Brindisi. If you're in the mood for something new, try Bento, another premier location with a delectable menu. You might also want to book a table at Cozza Nera. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Brindisi.

Head back to your accommodation in Brindisi and get some rest in preparation for another magical day of your road trip in Italy!

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Day 5

Day 5

  • Brindisi - Departure day
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  • Cillarese Park
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Cillarese Park, a visually striking park before you head out.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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