5-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling south to Syracuse

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Experience the freedom of the open road in Sicily as you embark on an unforgettable 5-day road trip! This experience caters to every traveler, featuring destinations like Catania, Syracuse, Noto, and Ragusa.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Catania and 2 nights in Syracuse. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Catania, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Neapolis Archaeological Park and Giardino Bellini are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Temple Of Apollo, learn more about the unique Nature Reserve Of Vendicari, and immerse yourself in the vibrant atmosphere of Castello Ursino.

As you hit the open road and drive through Catania, Syracuse, Noto, and Ragusa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Fountain of the ElephantBasilica Cattedrale di Sant'AgataVilla Bellini/Chiosco BelliniPiazza UniversitàCastello Ursino
Ear of DionysiusNeapolis Archaeological ParkFountain of DianaIsland of OrtigiaCathedral of Syracuse
Temple of ApolloRiserva Naturale Cavagrande del CassibileNature reserve of VendicariGiardino Ibleo

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Day 1

Day 1

  • Catania - Arrival day
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Say hello to Catania! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Catania for 1 night before you continue your adventure!

Catania is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Catania. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Ristorante da Antonio, a popular restaurant in Catania. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Catania at Lido Arcobaleno, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Lido Azzurro. It’s yet another ideal choice to enhance your time in Catania tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Caffè Europa, known for its inviting atmosphere. Insigne Cafè is another great option if you’re looking for a place to get the night started. Similarly, Bohéme Mixology Bar provides a great setting to enjoy the night away.

Raise a toast to the start of your 5-day road trip in Sicily!

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Day 2

Day 2

  • Catania
  • Syracuse
  • More

Drive 71 km, 1 hour 16 min

  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Villa Bellini/Chiosco Bellini
  • Piazza Università
  • Castello Ursino
  • More

On day 2 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 1 destination, Catania. When you’re not sightseeing, take time to relax at your selected hotel in Syracuse, where you’ll be staying for 2 nights.

Get ready for an exciting day in Catania. Today’s sightseeing agenda includes a monument, a church, a park, a public square, a castle and much more! Begin your adventure at Elephant Fountain. This is an underrated monument you should not miss. Another must-see is Catania Cathedral, an intriguing church in Catania.

When you’re ready for the next sight, head to Giardino Bellini. From there, take a leisurely stroll to Piazza Università, another of the city’s locally appreciated attractions. We recommend continuing your self-guided tour at Castello Ursino, a heritage-rich place of interest in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Syracuse. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Syracuse. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Prepare for an extraordinary culinary adventure in Syracuse by booking a table at Cortile Spirito Santo, a 1-star Michelin restaurant that boasts an exceptional creative and modern menu. If you're eager to try something different, consider Dock Café Restaurant, another top spot with a tantalizing menu.

Extend your evening after a delightful meal by visiting Barcollo, which offers the perfect atmosphere for a night out. Moreover, Bar Pasticceria Midolo is another popular option for a drink or two. Likewise, Boats also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Sicily.

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Day 3

Day 3

  • Syracuse
  • More

Drive 11 km, 36 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Fountain of Diana
  • Island of Ortigia
  • Cathedral of Syracuse
  • More

Day 3 offers a multitude of experiences. You will stay in Syracuse for 1 night more, offering you enough time to explore at a relaxed pace.

Today’s route brings family-friendly attractions, scenic views, and picturesque spots. The first attraction of today is Ear Of Dionysius. This up-and-coming cave is a picture-perfect place to see in Syracuse. Continue your discovery at Neapolis Archaeological Park, an UNESCO world heritage-designated archeological site with stories to tell.

As you stroll around Syracuse, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Diana Fountain. This intriguing monument offers a visually striking encounter with Syracuse. Next, make your way to Ortygia to add another highlight to your day. After that, visit Cathedral Of Syracuse, a curiosity-inducing church that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Syracuse.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Syracuse. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at La Lisca Cucina e Bottega, a highly recommended choice for tonight's dinner. If you're looking to mix things up, SICULISH HERE AND NOW offers an enticing alternative with its varied menu. Additionally, Ammucca - Sicilian Quality Meat Food is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Syracuse.

Continue the enjoyment post-dinner at Bar Tunisi, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Verga Courtyard - Cafeteria offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Glam Café. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Say good night to Syracuse and look forward to another great day of your road trip in Sicily!

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Day 4

Day 4

  • Syracuse
  • Catania
  • More

Drive 214 km, 4 hours 44 min

  • Temple of Apollo
  • Riserva Naturale Cavagrande del Cassibile
  • Nature reserve of Vendicari
  • Giardino Ibleo
  • More

Dive into day 4 of your remarkable road trip in Sicily. Today you will explore Syracuse, Noto, and Ragusa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Catania. You’ll stay here for 1 night.

Immerse yourself in Syracuse’s rich culture with today's sightseeing itinerary. Start your journey at Temple Of Apollo. This historic archeological site is sure to ignite your curiosity. Next, dive into the majestic features of Riserva Naturale Cavagrande Del Cassibile, a must-visit nature reserve in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Nature Reserve Of Vendicari, a well-known nature reserve. For a change of scene, check out Giardino Ibleo, known for its detailed features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Catania. Catania offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Catania's most popular restaurants, and connect with friendly locals for an authentic adventure.

Begin your culinary exploration in Catania by securing a reservation at Me Cumpari Turiddu. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of sicilian cuisine. For another dining delight, visit Sapio, celebrated for its delectable sicilian and modern menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Osteria Acqualavica, a top local spot known for its tantalizing sicilian and seafood menu. With a Bib Gourmand recognition, it guarantees an exceptional dining adventure.

After your meal, keep the night alive at a bar like Circus Cocktail Bar, known for its lively atmosphere. Caffè Opera is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Chiosco Sicilia Seltz offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day 5

Day 5

  • Catania - Departure day
  • More

Day 5 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Catania before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Make the most of your final day in Sicily by visiting Catania’s iconic markets and shopping establishments in the buzzing Centro Commerciale Porte di Catania. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Sicily.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Catania.

You’ll then say farewell to Catania. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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