5-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling south to Syracuse

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Piazza del Duomo in Catania on a summer day, with Duomo of Saint Agatha and the Elephant Fountain. Sicily, southern Italy. View of Cathedral Sant Agata on Piazza del Duomo in Catania, Sicily, Italy.
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Experience the freedom of the open road in Sicily as you embark on an unforgettable 5-day road trip! This experience caters to every traveler, featuring destinations like Catania, Syracuse, Noto, and Ragusa.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Catania and 2 nights in Syracuse. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Catania, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Neapolis Archaeological Park and Giardino Bellini are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Temple Of Apollo, learn more about the unique Nature Reserve Of Vendicari, and immerse yourself in the vibrant atmosphere of Castello Ursino.

As you hit the open road and drive through Catania, Syracuse, Noto, and Ragusa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
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Day
City & Overnight
Attractions
Fountain of the ElephantBasilica Cattedrale di Sant'AgataVilla Bellini/Chiosco BelliniPiazza UniversitàCastello Ursino
Ear of DionysiusNeapolis Archaeological ParkFountain of DianaIsland of OrtigiaCathedral of Syracuse
Temple of ApolloRiserva Naturale Cavagrande del CassibileNature reserve of VendicariGiardino Ibleo

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Day 1

Day 1

  • Catania - Arrival day
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Your road trip adventure in Sicily begins as soon as you reach Catania and pick up your car. You’ll stay in Catania for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Catania is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Catania. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

Savor the flavors at Ristorante da Antonio, a top pick for dinner tonight. Alternatively, Lido Arcobaleno beckons with its unique menu offerings. Also, consider Lido Azzurro. With its consistent customer satisfaction, it’s an excellent option for dining in Catania tonight.

After your meal, keep the night alive at a bar like Caffè Europa, known for its lively atmosphere. Insigne Cafè is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bohéme Mixology Bar offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 5-day road trip in Sicily!

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Day 2

Day 2

  • Catania
  • Syracuse
  • More

Drive 71 km, 1 hour 16 min

  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Villa Bellini/Chiosco Bellini
  • Piazza Università
  • Castello Ursino
  • More

Dive into day 2 of your remarkable road trip in Sicily. Today you will explore Catania, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Syracuse. You’ll stay here for 2 nights.

Immerse yourself in Catania’s rich culture with today's sightseeing itinerary. Start your journey at Elephant Fountain. This noteworthy monument is sure to ignite your curiosity. Next, dive into the visually striking features of Catania Cathedral, a must-visit church in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Giardino Bellini, a notable park. For a change of scene, check out Piazza Università, known for its romantic features. We also recommend visiting Castello Ursino. This castle is a must for anyone looking to experience the city to the fullest.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Syracuse. Syracuse offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Syracuse. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Get ready for an unforgettable culinary journey in Syracuse by reserving a table at Cortile Spirito Santo. Renowned as a 1-star Michelin restaurant, it offers an exceptional creative and modern menu. If you're in the mood to try something new, consider Dock Café Restaurant, another top spot with a mouthwatering menu.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Barcollo stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bar Pasticceria Midolo offers an ideal atmosphere to enjoy the pleasures of the night. Boats is also a great option that provides a perfect setting for a relaxing evening.

Say good night to Syracuse and look forward to another great day of your road trip in Sicily!

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Day 3

Day 3

  • Syracuse
  • More

Drive 11 km, 36 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Fountain of Diana
  • Island of Ortigia
  • Cathedral of Syracuse
  • More

Day 3 of your road trip across Sicily promises a magnificent time exploring Syracuse. You have 1 night left in Syracuse. Take the opportunity to experience more of the best attractions and activities in the city.

Get ready to discover some of the most iconic wonders in Syracuse, including a cave, an archeological site, a monument, a historical landmark, a church and much more! Start your day at Ear Of Dionysius. This eye-catching cave is a curiosity-inducing place to see in Syracuse. Then, wander over to Neapolis Archaeological Park. If historic sites excite you, this archeological site will be right up your alley. Nearby, you’ll also find Diana Fountain. This noteworthy monument is a favorite among visitors.

Syracuse offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Ortygia is an underrated spot in the city that will captivate you with its unique charm. When you’re done at the historical landmark, don’t forget to check out the history-steeped Cathedral Of Syracuse. Take a moment to appreciate the fascinating details of this increasingly popular church.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Syracuse, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at La Lisca Cucina e Bottega, a top-rated dining spot in Syracuse. If you're in the mood for something new, try SICULISH HERE AND NOW, another premier location with a delectable menu. You might also want to book a table at Ammucca - Sicilian Quality Meat Food. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Syracuse.

Round off your dining experience by visiting Bar Tunisi, a prime location for a drink. Alternatively, explore the distinctive characteristics of Verga Courtyard - Cafeteria, a bar catering to every mood and preference. Glam Café likewise offers a unique atmosphere, perfect for a memorable night out.

Head back to your accommodation in Syracuse and get some rest in preparation for another magical day of your road trip in Sicily!

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Day 4

Day 4

  • Syracuse
  • Catania
  • More

Drive 214 km, 4 hours 44 min

  • Temple of Apollo
  • Riserva Naturale Cavagrande del Cassibile
  • Nature reserve of Vendicari
  • Giardino Ibleo
  • More

On day 4 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 3 destinations, Syracuse, Noto, and Ragusa. When you’re not sightseeing, take time to relax at your selected hotel in Catania, where you’ll be staying for 1 night.

Today's adventure in Syracuse promises more breathtaking discoveries and enriching experiences! Begin at Temple Of Apollo. This stunning archeological site is a highlight of any visit in the city. Then, enjoy Riserva Naturale Cavagrande Del Cassibile, another eye-catching attraction that never fails to captivate visitors. Next, head over to Nature Reserve Of Vendicari, one of the city’s most locally renowned attractions, known for its mesmerizing features.

If you’re looking for more, spend time soaking in the atmosphere of Giardino Ibleo. This history-steeped botanical garden is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

When you’re done exploring for the day, you’ll drive to your hotel in Catania. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Catania. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Experience a taste of local culinary excellence while in Catania by securing a table at Me Cumpari Turiddu. An esteemed Bib Gourmand restaurant, it features an exceptional sicilian menu. For an alternative taste experience, visit Sapio, famous for its scrumptious sicilian and modern dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Osteria Acqualavica, a local favorite celebrated for its exquisite sicilian and seafood cuisine in Catania. Located in the heart of the city, this Bib Gourmand-awardee is an ideal pick for sicilian and seafood cuisine lovers seeking top-notch culinary experiences.

Continue your lively evening at Circus Cocktail Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Caffè Opera is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Chiosco Sicilia Seltz ensures a night out tailored to your taste.

Savor another day of unforgettable experiences in Sicily!

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Day 5

Day 5

  • Catania - Departure day
  • More

Day 5 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Catania before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

As your final day in Sicily unfolds, enjoy a last-minute shopping spree in Catania's best shopping area, Via Etnea. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Sicily. Browse through boutiques to find unique and stylish fashion pieces to take home.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Catania.

You’ll then say farewell to Catania. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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