5-Day Sicily Self-Drive Road Trip With Itinerary from Catania traveling south to Syracuse

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Piazza del Duomo in Catania on a summer day, with Duomo of Saint Agatha and the Elephant Fountain. Sicily, southern Italy. View of Cathedral Sant Agata on Piazza del Duomo in Catania, Sicily, Italy.
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Experience the freedom of the open road on an unforgettable 5-day road trip in Sicily! Embark on a self-drive tour that caters to every traveler, featuring destinations like Catania, Syracuse, Noto, and Ragusa.

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Catania and 2 nights in Syracuse. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Catania, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Neapolis Archaeological Park and Giardino Bellini are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Catania, Syracuse, Noto, and Ragusa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Catania - Arrival day
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Welcome to Catania, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Catania before embarking on the next leg of your journey.

Catania is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Catania. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Ristorante da Antonio, a top-rated dining destination in Catania. If you're in the mood to try something new, consider Lido Arcobaleno, another top spot with a mouthwatering menu. You might also want to secure a reservation at Lido Azzurro. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Catania this evening.

Continue your evening by exploring the vibrant nightlife scene at Caffè Europa, a prime destination for a thrilling night out. Also, don’t forget to check out Insigne Cafè, a bar that offers unique local touches. Likewise, Bohéme Mixology Bar provides an excellent alternative for a fun evening.

Raise a toast to the start of your 5-day road trip in Sicily!

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Day2

Day 2

  • Catania
  • Syracuse
  • More

Drive 71 km, 1 hour 16 min

  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Villa Bellini/Chiosco Bellini
  • Piazza Università
  • Castello Ursino
  • More

On day 2 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 1 destination, including Catania. When you’re not sightseeing, take time to relax at your chosen hotel in Syracuse, where you’ll be staying for 2 nights.

Catch Elephant Fountain before the crowds roll in. This photogenic monument is sure to ignite your curiosity. Next, dive into the enchanting features of Catania Cathedral, a must-visit church in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Giardino Bellini, a notable park. For a change of scene, check out Piazza Università, known for its enchanting features. We also recommend visiting Castello Ursino. This castle is a must for anyone looking to experience the city to the fullest.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Syracuse. Syracuse offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Syracuse is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Syracuse.

Have a memorable dining experience in Syracuse by booking a table at Cortile Spirito Santo, a 1-star Michelin restaurant presenting an exceptional creative and modern menu. Immerse yourself in the culinary delights of Dock Café Restaurant, a popular restaurant in Syracuse. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Cap off your dinner by heading to Barcollo, ideal for a leisurely evening with a drink in hand. Bar Pasticceria Midolo is another bar that offers an enjoyable setting. Similarly, Boats is also a popular place to go on a night out, perfect for relaxing and socializing.

Get a good night's sleep and look forward to another great day on the road in Sicily!

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Day3

Day 3

  • Syracuse
  • More

Drive 11 km, 36 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Fountain of Diana
  • Island of Ortigia
  • Cathedral of Syracuse
  • More

Day 3 of your road trip across Sicily promises a magnificent time exploring what to see in Syracuse. You have 1 night left in Syracuse. Take the opportunity to experience more of the best attractions and activities in the city.

Ear Of Dionysius brings Syracuse's character to life. This history-steeped cave is a highlight of any visit in the city. Then, enjoy Neapolis Archaeological Park, another UNESCO world heritage-designated attraction that never fails to captivate visitors. Next, head over to Diana Fountain, one of the city’s most frequently visited attractions, known for its enchanting features.

If you’re looking for more, spend time soaking in the atmosphere of Ortygia. This enchanting historical landmark is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Cathedral Of Syracuse, an up-and-coming church, and take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Syracuse's best restaurants.

Enjoy a delicious meal at La Lisca Cucina e Bottega, a top-rated dining destination in Syracuse. If you're in the mood to try something new, consider SICULISH HERE AND NOW, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ammucca - Sicilian Quality Meat Food. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Syracuse this evening.

Extend your evening after a delightful meal by visiting Bar Tunisi, which offers the perfect atmosphere for a night out. Moreover, Verga Courtyard - Cafeteria is another popular option for a drink or two. Likewise, Glam Café also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and recharge in preparation for another adventurous day in Sicily!

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Day4

Day 4

  • Syracuse
  • Noto
  • Ragusa
  • Catania
  • More

Drive 214 km, 4 hours 44 min

  • Temple of Apollo
  • Riserva Naturale Cavagrande del Cassibile
  • Nature reserve of Vendicari
  • Giardino Ibleo
  • More

On day 4 of your road trip in Sicily, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Syracuse, Noto, and Ragusa are on today's agenda. In the evening, you’ll end up in Catania, where you will stay for 1 night.

Enjoy all that Temple Of Apollo has to offer. This is a popular archeological site you should not miss.

Set your GPS to Noto and hit the road. Expect a journey of approximately 52 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Noto beckons with new experiences!

When you're ready for some sights, head to Riserva Naturale Cavagrande Del Cassibile, a worthwhile nature reserve in Noto. Explore its majestic features at your own pace before you continue your journey to your next attraction, Nature Reserve Of Vendicari. This well-known nature reserve is a top recommendation in the area.

After soaking in Noto’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Ragusa. Expect your car journey to take a minimum of 1 hour 13 min. When you arrive in Ragusa, it's time to take a break from the road.

Savor the day by heading to Giardino Ibleo, a beloved botanical garden that draws visitors from near and far.

At the end of the day, you will drive to Catania, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Catania's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy an outstanding dining experience at Me Cumpari Turiddu, a Bib Gourmand restaurant offering an exceptional sicilian menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Sapio, known for its delicious sicilian and modern cuisine. Another highly-recommended place to eat in Catania is Osteria Acqualavica, a renowned Bib Gourmand restaurant and a delicious sicilian and seafood menu.

If you’re not ready to end the night just yet, Circus Cocktail Bar offers a perfect venue to relax and savor a drink. Similarly, Caffè Opera is well-suited for those looking to unwind in a social setting. Chiosco Sicilia Seltz is another excellent spot to enjoy a nightcap after a delightful meal.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day5

Day 5

  • Catania - Departure day
  • More

Day 5 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Catania before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Take some time to indulge in shopping at Catania’s popular marketplace, Centro Commerciale Porte di Catania. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Catania.

If you're in the mood to try something new, consider Carlito's, another top spot with a mouthwatering menu.

You’ll then say farewell to Catania. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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