5-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence

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Genoa seaport, Italy
Photo of Sand beach in Camogli by Genoa, Italy.
5-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence
5-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence
5-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence
5-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence
5-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence
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Escape the ordinary with this exciting 5-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Genoa and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Genoa, Pisa, Florence, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Genoa - Arrival day
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  • Aquarium of Genoa
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Your road trip adventure in Italy begins as soon as you reach Genoa and pick up your car. You’ll stay here for 1 night and explore what to see in Genoa, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Genoa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at 7 Sensi cucina decontaminata, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Alla Lunga Ristorante offers an enticing alternative with its varied menu. Additionally, Grand Hotel Savoia is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Genoa.

Let the evening flow smoothly from dinner to drinks at Scurreria Beer & Bagel, a top-rated bar in the area. For other recommendations, La Lepre provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Pisacane Iii offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 5-day road trip in Italy!

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Day2

Day 2

  • Genoa
  • Pisa
  • Florence
  • More

Drive 275 km, 4 hours 8 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Basilica of Santa Maria Novella
  • piazzale Michelangelo
  • Porta Romana
  • More

On day 2 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Pisa and Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Pisa’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Genoa behind. This drive usually takes around 2 hours 6 min. Pisa welcomes you with a multitude of unique vacation experiences.

When you're ready for some sights, head to Leaning Tower Of Pisa, a timeless monument in Pisa. Explore its historic features at your own pace before you continue your journey to your next attraction, Piazza Del Duomo, Pisa. This timeless public square is a top recommendation in the area.

Embrace the thrill of the open road as you wave goodbye to Pisa and set your GPS to Florence. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 17 min. Upon reaching Florence, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Basilica Di Santa Maria Novella, Firenze (fi), a locally renowned church that everyone visiting Florence should see. Next, head to Piazzale Michelangelo. This culturally significant observation deck is one of the most spectacular attractions in the region.

If you're keen to see more, don’t miss out on Porta Romana, a symbolic monument popular among locals as well as travelers.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. Known for great service, it’s a fantastic choice for tonight in Florence.

Following your dinner, dive into the local bar culture at Manifattura. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Se·sto On Arno Rooftop Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Il Vinile provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day3

Day 3

  • Florence
  • More

Drive 2 km, 37 min

  • Galleria dell'Accademia
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • Palazzo Vecchio
  • Uffizi Gallery
  • Ponte Vecchio
  • More

On day 3 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

Galleria Dell'accademia is perfect for a self-paced visit during the day. This instagrammable art gallery is sure to impress. Next on your list is Cathedral Of Santa Maria Del Fiore, another must-visit landmark and spectacular church renowned for its inviting features.

While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Piazza Della Signoria. This enchanting public square is an essential place to visit for anyone looking for the full Florence experience. We also recommend visiting Palazzo Vecchio, a locally renowned palace. Nearby, you'll also find Uffizi Gallery, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Ponte Vecchio and wrap up your day with its visually striking appeal.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ditta Artigianale, a highly-rated dining destination in Florence. If you're eager to try something different, consider Trattoria Da Burde, another top spot with a tantalizing menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Continue the enjoyment post-dinner at Bar 50 Rosso, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bitter Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Archea Brewery. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day4

Day 4

  • Florence
  • Lucca
  • Genoa
  • More

Drive 240 km, 3 hours 22 min

  • Piazza dell'Anfiteatro
  • Guinigi Tower
  • St Martin Cathedral
  • Piazza Napoleone
  • Walls of Lucca
  • Porta San Pietro
  • More

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Lucca. When you’re not sightseeing, take time to relax at your chosen hotel in Genoa, where you’ll be staying for 1 night.

Fasten your seatbelt and make your way to your next stop — Lucca, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Lucca may take around 1 hour 11 min without traffic disruptions. Upon arrival in Lucca, we highly recommend checking out some of the top attractions.

Spend your afternoon discovering Piazza Dell'anfiteatro, a notable public square known for its history-steeped features. Next, continue your sightseeing at Guinigi Tower, an up-and-coming monument.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by St Martin Cathedral and uncover the details of this breathtaking church. Make sure to also explore Piazza Napoleone, a popular public square. For your last stop, consider Mura Di Lucca, a symbolic historical landmark that many travelers find worth the detour.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Genoa's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at Zeffirino, a top-rated dining spot in Genoa. If you're in the mood for something new, try Trattoria Vegia Zena, another premier location with a delectable menu. You might also want to book a table at Trattoria delle Grazie. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Genoa.

Relax and recharge in preparation for another adventurous day in Italy!

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Day5

Day 5

  • Genoa - Departure day
  • More
  • piazza De Ferrari
  • More

Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Piazza De Ferrari, a visually striking public square before you head out.

Take some time to indulge in shopping at Genoa’s popular marketplace, Via Garibaldi. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

Have a fantastic dining experience at Osteria Sant'Ilario, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Cialtroneria offers an enticing alternative with its varied menu.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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