5-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Pisa

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Explore the best of Italy on a 5-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Genoa, Vernazza, Corniglia, Manarola, Riomaggiore, Pisa, and Florence. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Genoa and 1 night in Pisa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Uffizi Gallery, and immerse yourself in the vibrant atmosphere of Aquarium Of Genoa.

As you hit the open road and drive through Genoa, Vernazza, Corniglia, Manarola, Riomaggiore, Pisa, and Florence, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Aquarium of Genoa
Galata - Museo del mareVia GaribaldiGenoa CathedralDoge's Palacepiazza De FerrariArea Marina Protetta di Portofino
Ruins of Doria TowerCinque Terre National ParkManarola Overlook ViewpointRiomaggiore
Leaning Tower of PisaPiazza del Duomo, PisaUffizi GalleryPonte VecchioPiazza della Repubblica
porto antico

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Day 1

Day 1

  • Genoa - Arrival day
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  • Aquarium of Genoa
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Welcome to Genoa, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Genoa's charm before embarking on the next leg of your journey.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aquarium Of Genoa, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Genoa. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at 7 Sensi cucina decontaminata, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Alla Lunga Ristorante, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Grand Hotel Savoia, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Scurreria Beer & Bagel, a well-loved spot among locals and tourists. Or, head to La Lepre. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Pisacane Iii, another top-rated place in the area.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2

  • Genoa
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Drive 87 km, 2 hours 42 min

  • Galata - Museo del mare
  • Via Garibaldi
  • Genoa Cathedral
  • Doge's Palace
  • piazza De Ferrari
  • Area Marina Protetta di Portofino
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Greet day 2 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Genoa for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Genoa and San Fruttuoso di Camogli.

Set out on a day brimming with family-friendly attractions, photo-friendly spots, and history-rich sites. Start at the worthwhile Galata Museo Del Mare (complex), an instagrammable maritime museum in Genoa. Next, go to Via Garibaldi.

After visiting Galata Museo Del Mare (complex) and Via Garibaldi, take time to explore Genoa's streets and absorb its charm. Continue your sightseeing by heading to Genoa Cathedral. This standout church offers a unique experience. Doge's Palace is another noteworthy stop. End your self-guided sightseeing tour on top with a visit to Piazza De Ferrari, one of the most enchanting places to visit in Genoa.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Dine in style at Zeffirino, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Vegia Zena boasts a menu that's sure to impress. Also, be sure to check out Trattoria delle Grazie. Known as a local hotspot, it’s a great choice for tonight in Genoa.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 3

Day 3

  • Genoa
  • Pisa
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Drive 228 km, 4 hours 29 min

  • Ruins of Doria Tower
  • Cinque Terre National Park
  • Manarola Overlook Viewpoint
  • Riomaggiore
  • More

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 4 vibrant destinations - Vernazza, Corniglia, Manarola, and Riomaggiore. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Pisa. You will spend 1 night here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Genoa today. One of the most underrated attractions included on the itinerary is Ruins Of Doria Tower. This visually striking monument will help you start your sightseeing on top. Then, take a leisurely stroll to Cinque Terre National Park and learn what makes this romantic national park unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the increasingly popular Manarola Overlook Viewpoint. After exploring the observation deck, head to Riomaggiore. This underrated sightseeing destination is a highlight in Genoa.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pisa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Anima di Grano Pizzeria Napoletana Pisa Italy, a highly recommended choice for tonight's dinner. If you're looking to mix things up, il Mercante offers an enticing alternative with its varied menu. Additionally, La Ghiotteria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pisa.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Jeffer Cocktails & Friends, known for its inviting atmosphere. Le Parisien Wine Bar is another great option if you’re looking for a place to get the night started. Similarly, Las Volta Cocktailbar provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 4

Day 4

  • Pisa
  • Genoa
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Drive 335 km, 4 hours 35 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • More

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Pisa and Florence, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Genoa. You’ll stay here for 1 night.

Today’s itinerary in Pisa covers several incredible sights, including a monument, a public square, an art gallery, a historical landmark and much more! Start your adventure at Leaning Tower Of Pisa. This timeless monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the breathtaking wonders of Piazza Del Duomo, Pisa, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Uffizi Gallery. This extraordinary art gallery offers an enriching experience. For a change of pace, head to Ponte Vecchio, where you can take in enchanting features. Conclude your self-guided sightseeing tour with a visit to Piazza Della Repubblica and Piazza Della Repubblica. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Osteria Sant'Ilario, a top pick for dinner tonight. Alternatively, La Cialtroneria beckons with its unique menu offerings. Also, consider Manhattan Bar. With its consistent customer satisfaction, it’s an excellent option for dining in Genoa tonight.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 5

Day 5

  • Genoa - Departure day
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  • porto antico
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porto Antico, a romantic public square before you head out.

Maximize your last day in Italy and go on a shopping spree in Genoa’s shopping center, the lively Porto Antico. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

Savor the flavors at Vivarelli, a top pick for dinner tonight. Alternatively, Trattoria Ugo beckons with its unique menu offerings.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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