5-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Pescara and Rome

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Escape the ordinary with this exciting 5-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Naples, 1 night in Pescara, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Naples, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of Roman Forum.

As you hit the open road and drive through Naples, Pescara, Orvieto, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
piazza del PlebiscitoOvo CastleNaples National Archaeological MuseumCappella Sansevero
Ponte del MareOrvieto CathedralWell of St Patrick
Roman ForumPantheonPiazza NavonaTrevi FountainColosseum

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Day 1

Day 1

  • Naples - Arrival day
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Your road trip adventure in Italy begins as soon as you reach Naples and pick up your car. You’ll stay in Naples for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Naples is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Naples. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Dine in style at L'Oca Nera Irish Pub, a top recommendation for dinner tonight. Or, for a change of pace, Mimì alla Ferrovia boasts a menu that's sure to impress. Also, be sure to check out Spuzzulè Winebar. Known as a local hotspot, it’s a great choice for tonight in Naples.

After savoring a delicious meal, step into the vibrant nightlife at Happening Cocktail Bar, where the evening is just getting started. In the same way, Shanti Art Musik Bar offers a unique charm perfect for experiencing the local bar scene in Naples. Gran Caffè Gambrinus is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2

  • Naples
  • Pescara
  • More

Drive 258 km, 4 hours 4 min

  • piazza del Plebiscito
  • Ovo Castle
  • Naples National Archaeological Museum
  • Cappella Sansevero
  • More

Dive into day 2 of your remarkable road trip in Italy. Today you will explore Naples, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pescara. You’ll stay here for 1 night.

Savor the day by visiting some of the best places to see in Naples, including a public square, a castle, and a museum. Start your adventure at Piazza Del Plebiscito. This impressive public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Ovo Castle located in Naples for an enchanting atmosphere.

Next, immerse yourself in the setting of Naples National Archaeological Museum. Its history-steeped features will captivate you. After the museum, continue your tour of the city with a visit to Cappella Sansevero. This museum has a detailed appeal.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pescara. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Set out on a gastronomic journey in Pescara by reserving a table at Nole. Renowned for its Bib Gourmand award, this restaurant presents an outstanding menu of italian contemporary and italian cuisine. For a different taste, head over to Estrò, renowned for its delectable contemporary and country cooking dishes. This distinguished Bib Gourmand-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Taverna 58, a highly rated local gem known for its exquisite from abruzzo and traditional menu. With a Bib Gourmand acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Pescara.

Extend your evening after a delightful meal by visiting Posa Caffè Pescara, which offers the perfect atmosphere for a night out. Moreover, Bar Mixer is another popular option for a drink or two. Likewise, Temple Bar Irish Pub also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Pescara
  • Rome
  • More

Drive 437 km, 4 hours 55 min

  • Ponte del Mare
  • Orvieto Cathedral
  • Well of St Patrick
  • More

On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pescara and Orvieto. In the evening, you’ll end up in Rome, where you will stay for 1 night.

Today’s route brings family-friendly attractions, romantic experiences, and breathtaking views. The first attraction of today is Ponte Del Mare. This worthwhile boardwalk is an instagrammable place to see in Pescara. Continue your discovery at Orvieto Cathedral, an enchanting church with stories to tell.

As you stroll around Pescara, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Well Of St. Patrick. This interesting monument offers an instagrammable encounter with Pescara. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Pescara.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy an outstanding dining experience at La Pergola, a 3-star Michelin restaurant offering an exceptional mediterranean and contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 2-star Michelin-awardee, Il Pagliaccio, known for its delicious creative and innovative cuisine. Another highly-recommended place to eat in Rome is Enoteca La Torre, a renowned restaurant with a 2-star Guide Michelin recognition and a delicious mediterranean and creative menu.

Keep the excitement of the evening going by visiting a bar or two. La Botticella Of Poggi Giovanni is an excellent place to start. You could also check out Almalu Trastevere, offering a different kind of charm. A last recommendation for the day is Bar Viminale Di Pepi Maurilio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 4

Day 4

  • Rome
  • Naples
  • More

Drive 236 km, 3 hours 11 min

  • Roman Forum
  • Pantheon
  • Piazza Navona
  • Trevi Fountain
  • Colosseum
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Naples, which will be your home away from home for 1 night.

Start by visiting Roman Forum, a prime spot to begin your journey. This picture-perfect archeological site is sure to impress. Next on your list is Pantheon, another must-visit landmark and world-famous monument renowned for its photogenic features.

While exploring and sightseeing, take time to savor the ambiance of Rome by sampling some local delicacies or having a drink. When you’re ready for more sightseeing, head to Piazza Navona. This romantic public square is a remarkable attraction that offers a unique experience. Trevi Fountain also adds charm to your journey, and Colosseum wraps up your day with its historic appeal.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.

Discover the culinary delights of Naples by securing a reservation at Veritas. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of campanian and contemporary cuisine. For an alternative dining experience, try Il Comandante, renowned for its delicious creative and mediterranean dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to ARIA, a highly recommended local eatery celebrated for its mouthwatering contemporary and modern menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Continue your evening by exploring the vibrant nightlife scene at Archivio Storico - Cocktail Bar & Wonderfood, a prime destination for a thrilling night out. Also, don’t forget to check out Archeobar, a bar that offers unique local touches. Likewise, Babette Pub provides an excellent alternative for a fun evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 5

Day 5

  • Naples - Departure day
  • More

Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Naples before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Make the most of your final day in Italy by visiting Naples’s iconic markets and shopping establishments in the buzzing Via Toledo. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Naples.

Treat yourself to a delicious dinner at Opera Restaurant, an excellent option for tonight's dining. Looking for something different? Trattoria San Ferdinando offers a tantalizing alternative with its diverse menu. And don’t miss Anonymous Trattoria Gourmet.

You’ll then say farewell to Naples. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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