5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento

Day 2 offers a multitude of experiences. You will stay in Palermo for 1 night more, offering you enough time to explore at a relaxed pace.

Savor the day by visiting some of the best places to see in Palermo, including a monument, a public square, a church, a nature reserve and much more! Start your adventure at Fontana Pretoria. This increasingly popular monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Quattro Canti located in Palermo for an enchanting atmosphere.

Next, immerse yourself in the setting of Martorana. Its historic features will captivate you. After the church, continue your tour of the city with a visit to Riserva Naturale Di Capo Gallo. This nature reserve has a romantic appeal. For a change of pace, head to Santuario Di Santa Rosalia, Palermo. As one of the most increasingly popular attractions in Palermo, this church is an excellent place to end your self-guided tour.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for an authentic adventure.

Prepare for an extraordinary culinary adventure in Palermo by booking a table at Buatta Cucina Popolana, a Bib Gourmand restaurant that boasts an exceptional sicilian menu. For a different flavor experience, head to Mec Restaurant, renowned for its delectable sicilian and contemporary dishes. This 1-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Gagini Restaurant, a local gem known for its delightful creative and contemporary cuisine in Palermo. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

After your meal, keep the night alive at a bar like Spina Bar Palermo, known for its lively atmosphere. Torrefazione Castagnetta Massimiliano (gelateria) is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Monkey Pub offers an excellent atmosphere for those looking to amp up the evening.

Head back to your accommodation in Palermo and get some rest in preparation for another magical day of your road trip in Sicily!

Embark on another extraordinary experience on day 3 of your road trip in Sicily. Today, you will make 1 stop and experience some of the highlights of Palermo. At the end of the day, you will enjoy the comforts of a top-rated hotel in Agrigento, which will be your home away from home for 1 night.

Today’s route brings fun adventures, breathtaking views, and picturesque spots. The first attraction of today is Norman Palace. This well-known palace is a breathtaking place to see in Palermo. Continue your discovery at Palermo Cathedral, a picture-perfect church with stories to tell.

As you stroll around Palermo, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Orto Botanico Di Palermo. This increasingly popular botanical garden offers an eye-catching encounter with Palermo. Catacombe Dei Cappuccini is the last of our recommendations for today. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Palermo.

When you’re done exploring for the day, you’ll drive to your hotel in Agrigento. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Agrigento, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Get ready for an unforgettable culinary journey in Agrigento by reserving a table at Osteria Expanificio. Renowned as a Bib Gourmand restaurant, it offers an exceptional sicilian and traditional menu. If you're in the mood to try something new, consider Le Cuspidi, another top spot with a mouthwatering menu.

Say good night to Agrigento and look forward to another great day of your road trip in Sicily!

Dive into day 4 of your remarkable road trip in Sicily. Today you will explore Xitta, San Vito Lo Capo, and Castellammare del Golfo, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo. You’ll stay here for 1 night.

Xitta’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Agrigento behind. This drive usually takes around 2 hours 8 min. Xitta welcomes you with a multitude of unique vacation experiences.

Begin your journey at Saline Di Trapani E Paceco and explore the serene features.

When you’re ready to jump back into the car and say goodbye to Xitta, you’ll hit the road in the direction of San Vito Lo Capo. This drive usually takes around 47 min. When you arrive, enjoy some sightseeing.

Your self-guided tour starts at Riserva Naturale Orientata Dello Zingaro, Ingresso Sud, an intriguing nature reserve that is sure to impress. Take in the surroundings and enjoy the freedom of exploring before you continue your journey.

Castellammare del Golfo’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of San Vito Lo Capo behind. This drive usually takes around 24 min. Castellammare del Golfo welcomes you with a multitude of unique vacation experiences.

Take your self-guided tour to Belvedere Castellammare Del Golfo, a beloved observation deck that everyone visiting Castellammare del Golfo should see. Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Next, head to Marina Di Castellammare Del Golfo. This gorgeous marina is one of the most beloved attractions in the region.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Palermo. Palermo offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at Splendid Hotel la Torre, a top-rated dining destination in Palermo. If you're in the mood to try something new, consider Ristorantino Sobremesa, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Quattro mani. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Palermo this evening.

After savoring a delicious meal, step into the vibrant nightlife at Bar Touring, where the evening is just getting started. In the same way, Palermo Football Store offers a unique charm perfect for experiencing the local bar scene in Palermo. Goccio - L’arte Del Miscelare is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Get a good night's sleep and look forward to another great day on the road in Sicily!