5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina

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Photo of Palermo City, Sicily island in Italy. Aerial view of beautiful Mediterranean town. Drone Photography.
Photo of Palermo, Sicily, Italy. Seafront view.
5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina
5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina
5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina
5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina
5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina
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Escape the ordinary with this exciting 5-day road trip through Sicily. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Palermo, 1 night in Agrigento, and 1 night in Taormina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Agrigento, Piazza Armerina, Taormina, Syracuse, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 1 night before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Cotto e Bollito, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bebop? It's another excellent option with a diverse menu. Consider reserving a table at Eremiti Restaurant as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Palermo.

After enjoying a fulfilling meal, continue your evening at Malox Cult, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Ai Giudici offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Italico provides an excellent environment for a relaxed and enjoyable evening.

Raise a toast to the start of your 5-day road trip in Sicily!

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Day2

Day 2

  • Palermo
  • Agrigento
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Drive 138 km, 2 hours 53 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Valle dei Templi
  • More

On day 2 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 2 destinations, including Palermo and Agrigento. When you’re not sightseeing, take time to relax at your chosen hotel in Agrigento, where you’ll be staying for 1 night.

Make time for Norman Palace, a well-known palace that is worthwhile a visit in the city. Nearby, you’ll find Palermo Cathedral, enchanting visitors with its grand appeal. Continue your exploration at Quattro Canti. This public square is one of the city’s most well-known spots.

Enjoy the freedom of exploring Palermo at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Fontana Pretoria. After exploring the monument, head to the beloved Orto Botanico Di Palermo.

Fasten your seatbelt and make your way to your next stop — Agrigento, home to many well-known sights in the region. Keep in mind that your travel time from Palermo to Agrigento may take around 1 hour 59 min without traffic disruptions. Upon arrival in Agrigento, we highly recommend checking out some of the top attractions.

Savor the day by heading to Valle Dei Templi, an interesting archeological site that draws visitors from near and far.

When you’re done exploring for the day, you’ll drive to your hotel in Agrigento. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Agrigento, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Ambasciata di Sicilia, a popular restaurant in Agrigento. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Agrigento at Le Cuspidi, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Yellove RistoVintage. It’s yet another ideal choice to enhance your time in Agrigento tonight.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

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Day3

Day 3

  • Agrigento
  • Piazza Armerina
  • Taormina
  • More

Drive 252 km, 4 hours 32 min

  • Villa Romana del Casale
  • Grotta Azzurra
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • Porta Catania
  • Basilica of St. Nicholas of Bari
  • More

On day 3 of your road trip in Sicily, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Piazza Armerina, Mazzarò, and Taormina are on today's agenda. In the evening, you’ll end up in Taormina, where you will stay for 1 night.

Fasten your seatbelt and make your way to your next stop — Piazza Armerina, home to many well-known sights in the region. Keep in mind that your travel time from Agrigento to Piazza Armerina may take around 1 hour 23 min without traffic disruptions. Upon arrival in Piazza Armerina, we highly recommend checking out some of the top attractions.

Spend your afternoon discovering Villa Romana Del Casale, a locally renowned archeological site known for its historic features.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Mazzarò may take around 2 hours 6 min. Upon your arrival in Mazzarò, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you're ready for some sights, head to Grotta Azzurra, an often recommended cave in Mazzarò. Explore its mesmerizing features at your own pace before you continue your journey to your next attraction, Ancient Theatre Of Taormina. This notable archeological site is a top recommendation in the area.

When you arrive in Taormina, it's time to take a break from the road.

One of our top recommendations for your sightseeing is Villa Comunale Di Taormina. Spend some time admiring the awe-inspiring features of the park before you continue to your next stop. Then, head to Porta Catania. This intriguing monument is a traveler-favorite in the town.

If you're keen to see more, continue to Basilica Of St. Nicholas Of Bari. Feed your curiosity by learning something new about the church.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Taormina. Taormina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Taormina's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at PizzaMania Taormina, a top-rated dining destination in Taormina. If you're in the mood to try something new, consider Ristorante Pizzeria Tiramisù Taormina, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Pignolata Guinness Cannoli Taormina {since 1978} N°15. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Taormina this evening.

Following your dinner, dive into the local bar culture at Luraleo Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Don Diego Gelateria Caffetteria, the perfect place for those looking to experience the best of the nightlife.

Get a good night's sleep and look forward to another great day on the road in Sicily!

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Day4

Day 4

  • Taormina
  • Syracuse
  • Cefalù
  • Palermo
  • More

Drive 424 km, 5 hours 25 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Temple of Apollo
  • Cathedral of Cefalù
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • More

Dive into day 4 of your remarkable road trip in Sicily. Today you'll explore 2 destinations, including Syracuse and Cefalù. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo, where you'll spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Taormina and set your GPS to Syracuse. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 24 min. Upon reaching Syracuse, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

For a more meaningful self-guided tour of the city's best attractions, visit Ear Of Dionysius, an often recommended cave that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Neapolis Archaeological Park and admire its breathtaking features.

When you’re ready, continue to Temple Of Apollo, a well-known archeological site beloved by locals and tourists alike.

After soaking in Syracuse’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Cefalù. Expect your car journey to take a minimum of 2 hours 44 min. When you arrive in Cefalù, it's time to take a break from the road.

Cefalù Cathedral is an interesting church we recommend visiting today. Discover its symbolic features before continuing your self-guided tour to Lavatoio Medievale Fiume Cefalino - Cefalù (pa), a visually striking historical landmark that’s well-regarded in the area.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Palermo is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Palermo.

Treat yourself to a wonderful meal at Osteria Mercede, a top-rated dining spot in Palermo. If you're in the mood for something new, try Trattoria Del Massimo, another premier location with a delectable menu. You might also want to book a table at Grand Hotel Piazza Borsa. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Palermo.

After savoring a delicious meal, step into the vibrant nightlife at Spina Bar Palermo, where the evening is just getting started. In the same way, Torrefazione Castagnetta Massimiliano (gelateria) offers a unique charm perfect for experiencing the local bar scene in Palermo. Monkey Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day5

Day 5

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
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Day 5 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Catacombe Dei Cappuccini, an inviting cemetery before you head out.

Make the most of your final day in Sicily by visiting Palermo’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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