5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and Taormina

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Explore the best of Sicily on a 5-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Palermo, Agrigento, Piazza Armerina, Taormina, Syracuse, and Cefalù. This road trip itinerary in Sicily seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 2 nights in Palermo, 1 night in Agrigento, and 1 night in Taormina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Ancient Theatre Of Taormina, learn more about the unique Quattro Canti, and immerse yourself in the vibrant atmosphere of Norman Palace.

As you hit the open road and drive through Palermo, Agrigento, Piazza Armerina, Taormina, Syracuse, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Foro Italico
Norman PalacePalermo CathedralQuattro CantiFontana PretoriaOrto botanico di PalermoValle dei Templi
Villa Romana del CasaleGrotta AzzurraVilla Comunale di TaorminaAncient theatre of TaorminaPorta CataniaBasilica of St. Nicholas of Bari
Ear of DionysiusNeapolis Archaeological ParkTemple of ApolloCathedral of CefalùLavatoio Medievale Fiume Cefalino - Cefalù (pa)
Catacombe dei Cappuccini

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Your road trip adventure in Sicily begins as soon as you reach Palermo and pick up your car. You’ll stay in Palermo for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Palermo. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Cotto e Bollito, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bebop offers an enticing alternative with its varied menu. Additionally, Eremiti Restaurant is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Palermo.

If you’re not ready to end the night just yet, Malox Cult offers a perfect venue to relax and savor a drink. Similarly, Ai Giudici is well-suited for those looking to unwind in a social setting. Bar Italico is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 5-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
  • Agrigento
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Drive 138 km, 2 hours 53 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Valle dei Templi
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On day 2 of your road trip in Sicily, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Palermo and Agrigento. In the evening, you’ll end up in Agrigento, where you will stay for 1 night.

Today’s agenda in Palermo includes a palace, a church, a public square, a monument, a botanical garden, an archeological site and much more! Norman Palace is must-visit palace and a great starting point for the day. Next, continue your journey to Palermo Cathedral, an interesting church, located just a leisurely stroll away. Next, head to Quattro Canti, an enchanting public square, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Palermo. When you're ready, let your sightseeing route take you to the often recommended Fontana Pretoria. If you’re looking for more, Orto Botanico Di Palermo is also an intriguing attraction that is worthwhile a visit. Lastly, don’t miss Valle Dei Templi, a place of picture-perfect interest in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Agrigento. Agrigento offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Agrigento. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Ambasciata di Sicilia, an iconic dining spot in Agrigento. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Le Cuspidi, a popular restaurant in Agrigento. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Yellove RistoVintage, a hidden gem nestled in Agrigento. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day 3

Day 3

  • Agrigento
  • Taormina
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Drive 252 km, 4 hours 32 min

  • Villa Romana del Casale
  • Grotta Azzurra
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • Porta Catania
  • Basilica of St. Nicholas of Bari
  • More

Embark on another extraordinary experience on day 3 of your road trip in Sicily. Today, you will make 3 stops and experience some of the highlights of Piazza Armerina, Mazzarò, and Taormina. At the end of the day, you will enjoy the comforts of a top-rated hotel in Taormina, which will be your home away from home for 1 night.

Agrigento is brimming with adventures. Today’s wonderful stops include an archeological site, a cave, a park, a monument, a church and much more! Begin your sightseeing adventure at the locally renowned Villa Romana Del Casale and allow yourself time to explore. Just a short distance away you'll find your next stop, Grotta Azzurra, a romantic cave that draws visitors from far and near.

Continue your journey to Villa Comunale Di Taormina, one of the town’s most intriguing spots that you shouldn’t miss. Another great site to visit is the well-known Ancient Theatre Of Taormina. When you're finished at the archeological site, Porta Catania awaits your visit. This monument is a symbolic highlight on today's itinerary. Last up is a church - the up-and-coming Basilica Of St. Nicholas Of Bari.

When you’re done exploring for the day, you’ll drive to your hotel in Taormina. Check in and spend some time relaxing before you head out to tour the town.

As dinnertime approaches, it's time to head out for a bite to eat in Taormina. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at PizzaMania Taormina, a highly-rated dining destination in Taormina. If you're eager to try something different, consider Ristorante Pizzeria Tiramisù Taormina, another top spot with a tantalizing menu. You might also want to secure a reservation at La Pignolata Guinness Cannoli Taormina since 1978 N°15. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Taormina this evening.

Unwind after your meal by stepping into Luraleo Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Don Diego Gelateria Caffetteria offers a dynamic and energetic atmosphere for a glass or two.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Sicily.

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Day 4

Day 4

  • Taormina
  • Palermo
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Drive 424 km, 5 hours 25 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Temple of Apollo
  • Cathedral of Cefalù
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • More

Dive into day 4 of your remarkable road trip in Sicily. Today you will explore Syracuse and Cefalù, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo. You’ll stay here for 1 night.

Taormina is home to plenty of attractions that offer fun adventures, breathtaking views, and picturesque spots! Start at Ear Of Dionysius, an often recommended cave that is worthwhile a visit in the city. Nearby, you’ll find Neapolis Archaeological Park, enchanting visitors with its historic appeal. Continue your exploration at Temple Of Apollo. This archeological site is one of the city’s most notable spots.

Enjoy the freedom of exploring Taormina at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Cefalù Cathedral. After exploring the church, head to the intriguing Lavatoio Medievale Fiume Cefalino - Cefalù (pa).

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Osteria Mercede, a top-rated dining destination in Palermo. If you're in the mood to try something new, consider Trattoria Del Massimo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Grand Hotel Piazza Borsa. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Palermo this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Spina Bar Palermo, a well-loved spot among locals and tourists. Or, head to Torrefazione Castagnetta Massimiliano (gelateria). This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Monkey Pub, another top-rated place in the area.

Get a good night's sleep and look forward to another great day on the road in Sicily!

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Day 5

Day 5

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
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Day 5 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Catacombe Dei Cappuccini, a photogenic cemetery before you head out.

On your last day in Sicily, take time to indulge in shopping at Palermo’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

Have a fantastic dining experience at Splendid Hotel la Torre, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorantino Sobremesa offers an enticing alternative with its varied menu.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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