5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and surrounding area

Day 2 offers an itinerary packed with the best things to see in Palermo. You’ll stay in Palermo for 1 night more, offering you enough time to explore at a relaxed pace.

Fontana Pretoria leaves a lasting impression. This monument is one of the most often recommended places to visit in Palermo. Next, head to Quattro Canti, a popular public square, known for its enchanting features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Martorana. This majestic church is a highly recommended experience. Nearby, you'll also find Riserva Naturale Di Capo Gallo and Santuario Di Santa Rosalia, Palermo Visit these for an interesting touch to your journey.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine.

Experience a taste of local culinary excellence while in Palermo by securing a table at Buatta Cucina Popolana. An esteemed Bib Gourmand restaurant, it features an exceptional sicilian menu. For an alternative taste experience, visit Mec Restaurant, famous for its scrumptious sicilian and contemporary dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Gagini Restaurant, a local favorite celebrated for its exquisite creative and contemporary cuisine in Palermo. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for creative and contemporary cuisine lovers seeking top-notch culinary experiences.

Continue the enjoyment post-dinner at Spina Bar Palermo, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Torrefazione Castagnetta Massimiliano (gelateria) offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Monkey Pub. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Head back to your accommodation in Palermo and get some rest to prepare for another magical day of your road trip in Sicily.

On day 3 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 1 destination, including Palermo. When you’re not sightseeing, take time to relax at your chosen hotel in Agrigento, where you’ll be staying for 1 night.

Norman Palace is an ideal stop early in the day. This captivating palace is a must-visit in the city. When you’re ready for your next discovery, continue to Palermo Cathedral, which may be one of the most breathtaking places you will experience today.

One of the best things about exploring Palermo on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Orto Botanico Di Palermo, an increasingly popular botanical garden in the city. If you’re up for more discoveries, don’t forget to reserve some time for Catacombe Dei Cappuccini.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Agrigento is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Agrigento.

Savor the flavors at Ambasciata di Sicilia, a top pick for dinner tonight. Alternatively, Le Cuspidi beckons with its unique menu offerings. Also, consider Yellove RistoVintage. With its consistent customer satisfaction, it’s an excellent option for dining in Agrigento tonight.

Head back to your accommodation in Agrigento and get some rest to prepare for another magical day of your road trip in Sicily.

Experience an unparalleled adventure on day 4 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Xitta, San Vito Lo Capo, and Castellammare del Golfo. At the end of the day, you will retreat to the hotel of your choice in Palermo, where will spend 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Xitta. This drive usually takes around 2 hours 8 min, without any stops or traffic disruptions.

One of our top recommendations for your sightseeing is Saline Di Trapani E Paceco. Spend some time admiring the eye-catching features of the nature reserve before you continue to your next stop.

San Vito Lo Capo’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Xitta behind. This drive usually takes around 47 min. San Vito Lo Capo welcomes you with a multitude of unique vacation experiences.

One of our top recommendations for your sightseeing is Riserva Naturale Orientata Dello Zingaro, Ingresso Sud. Spend some time admiring the majestic features of the nature reserve before you continue to your next stop.

Fasten your seatbelt and make your way to your next stop — Castellammare del Golfo, home to many well-known sights in the region. Keep in mind that your travel time from San Vito Lo Capo to Castellammare del Golfo may take around 24 min without traffic disruptions. Upon arrival in Castellammare del Golfo, we highly recommend checking out some of the top attractions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Belvedere Castellammare Del Golfo, an often recommended observation deck that everyone visiting Castellammare del Golfo should see. Next, head to Marina Di Castellammare Del Golfo. This romantic marina is one of the most increasingly popular attractions in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Palermo. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Palermo's best restaurants.

Dine in style at Splendid Hotel la Torre, a top recommendation for dinner tonight. Or, for a change of pace, Ristorantino Sobremesa boasts a menu that's sure to impress. Also, be sure to check out Ristorante Quattro mani. Known as a local hotspot, it’s a great choice for tonight in Palermo.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Bar Touring, known for its inviting atmosphere. Palermo Football Store is another great option if you’re looking for a place to get the night started. Similarly, Goccio - L’arte Del Miscelare provides a great setting to enjoy the night away.

Relax and recharge in preparation for another adventurous day in Sicily!