5-Day Italy Road Trip from Perugia traveling south to Rome

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Escape the ordinary with this exciting 5-day road trip through Italy. Explore the diverse landscapes and local cultures of Perugia, Pale, Pissignano, Spoleto, and Rome. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Perugia, Pale, Pissignano, Spoleto, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1 – Perugia - arrival day

  • Perugia - Arrival day
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  • Piazza IV Novembre
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Your road trip adventure in Italy begins as soon as you reach Perugia and pick up your car. You’ll stay in Perugia for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Iv Novembre or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Perugia. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ristorante Settimo Sigillo, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bar Pellas, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Taverna, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Tommi Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Valentina, which offers a similarly pleasant setting and great drinks. Another option is Caffe Dal Perugino, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2 – Perugia, Pale, Rasiglia, Pissignano, Spoleto, and Rome

  • Rome
  • Pale
  • Pissignano
  • Spoleto
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Drive 240 km, 3 hours 56 min

  • Fonti del Clitunno
  • Spoleto Cathedral
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Dive into day 2 of your remarkable road trip in Italy. Today you will explore Pale, Rasiglia, Pissignano, and Spoleto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 2 nights.

Fasten your seatbelt and make your way to your next stop. Pale, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Perugia to Pale may take around 48 min without traffic disruptions. Upon arrival in Pale, we highly recommend checking out some of the top attractions.

Make Menotre Rainfalls your first stop of the day. Previous visitors have rated this point of interest an average of 4.5 out of 5 stars in 2,631 reviews.

After soaking in Pale’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Rasiglia. Expect your car journey to take a minimum of 17 min. When you arrive in Rasiglia, it's time to take a break from the road.

Your sightseeing of the day begins at Borgo Di Rasiglia, a remarkable sightseeing destination where it’s easy to get lost in exploration. This top attraction is rated an average of 4.6 out of 5 stars in 9,277 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Prepare for an extraordinary culinary adventure in Rome by booking a table at La Pergola, a 3-star Michelin restaurant that boasts an exceptional mediterranean, and contemporary menu. For a different flavor experience, head to Il Pagliaccio, renowned for its delectable creative, and innovative dishes. This 2-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Enoteca La Torre, a local gem known for its delightful mediterranean, and creative cuisine in Rome. Nestled in the city's heart, this 2-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Extend your evening after a delightful meal by visiting La Botticella Of Poggi Giovanni, which offers the perfect atmosphere for a night out. Moreover, Sant' Eustachio Caffè is another popular option for a drink or two. Likewise, Caffè Portofino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Savor another day of unforgettable experiences in Italy!

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Day 3

Day 3 – Rome

  • Rome
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Drive 9 km, 1 hour 11 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Piazza Navona
  • Castel Sant'Angelo
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Day 3 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Make Colosseum one of your first sightseeing stops in Rome. Rated an average of 4.7 out of 5 stars by 328,821 travelers, a visit to this local attraction makes for a great introduction to the area. This roman amphitheatre attracts 7,400,000 visitors every year.

Roman Forum is a worthwhile attraction you can visit next. This square is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 114,450 reviews.

Today is also the perfect opportunity to drop by Pantheon. This roman temple has been rated an average of 4.8 out of 5 stars by 189,682 visitors. Up to 30,000,000 people travel to this site annually.

If you’re keen to explore more, head to Piazza Navona. A trip to this popular square is also your opportunity to see if it lives up to the reputable 4.7 out of 5-star rating as given by 158,771 previous visitors.

Another top place to visit is Castel Sant'angelo. This museum enjoys an average rating of 4.7 out of 5 stars from 72,431 local and international travelers. Approximately 918,591 people visit this attraction every year.

Your discoveries in Rome do not have to stop there. Check out the fantastic selection of tours and tickets offered in Rome on this day of your trip. You can select your tours below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at DEROMA - Farine Romane, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Rome this evening.

After enjoying a fulfilling meal, continue your evening at The Apartment Bar Roma, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hotel Hassler Roma offers a welcoming atmosphere for easing into the nightlife.

Raise your glass to another unforgettable day in Italy!

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Day 4

Day 4 – Rome, Vatican City, and Perugia

  • Perugia
  • Rome
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Drive 184 km, 3 hours 17 min

  • Trevi Fountain
  • Piazza di Spagna
  • Piazza del Popolo
  • Villa Borghese
  • St Peter's Basilica
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On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Rome, and Vatican City. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.

Your sightseeing of the day begins at Trevi Fountain, a remarkable sculpture where it’s easy to get lost in exploration. This top attraction is rated an average of 4.8 out of 5 stars in 343,494 reviews.

Next, satisfy your wanderlust at Piazza Di Spagna. This square has an average rating of 4.7 out of 5 stars from 113,658 travelers.

Piazza Del Popolo is another must-visit attraction. This renowned square offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.6 out of 5 stars by 89,807 travelers, it's one of the more popular places to see in the area.

Beyond the above-mentioned sites, you also have the opportunity to visit Villa Borghese. This well-loved urban zone of rome boasts a 4.6 out of 5-star rating from 69,749 reviews.

Set your GPS to Vatican City, Vatican City and hit the road. Expect a journey of approximately 13 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Vatican City beckons with new experiences!

Take the opportunity to see St. Peter's Basilica. This attraction has an average rating of 4.8 out of 5 stars from 131,043 visitors and gets around 11,000,000 visits every year.

When you’re done exploring for the day, you’ll drive to Perugia, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Ristorante del Sole, a top-rated dining spot in Perugia. If you're in the mood for something new, try Al Mangiar Bene, another premier location with a delectable menu. You might also want to book a table at Elfo Pub Perugia. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Perugia.

Following your dinner, dive into the local bar culture at Caffè Fortebraccio. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Caffe Del Banco, the perfect place for those looking to experience the best of the nightlife. Similarly, Dempsey's Perugia provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 5

Day 5 – Perugia - departure day

  • Perugia - Departure day
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  • Rocca Paolina
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Perugia's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Journey into the unknown at Rocca Paolina, a unique attraction awaiting your visit. This remarkable rocca has an average rating of 4.7 out of 5 stars from 7,128 reviews.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.

If you're eager to try something different, consider Osteria a Priori, another top spot with a tantalizing menu.

You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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