6-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Sorrento and Rome

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Escape the ordinary with this exciting 6-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Brindisi, 1 night in Sorrento, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Pantheon are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Brindisi, Matera, Alberobello, Positano, Amalfi, Ravello, Sorrento, Pompei, Ottaviano, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Brindisi - Arrival day
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  • Swabian Castle of Brindisi
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Your road trip adventure in Italy begins as soon as you reach Brindisi and pick up your car. You’ll stay here for 2 nights and explore what to see in Brindisi, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Swabian Castle Of Brindisi. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Brindisi. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Bracerie Escosazio, a top-rated dining destination in Brindisi. If you're in the mood to try something new, consider Penny, another top spot with a mouthwatering menu. You might also want to secure a reservation at Piadineria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brindisi this evening.

Extend your evening after a delightful meal by visiting Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, which offers the perfect atmosphere for a night out. Moreover, Eden Cafè is another popular option for a drink or two.

Raise a toast to the start of your 6-day road trip in Italy!

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Day2

Day 2

  • Brindisi
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Drive 305 km, 4 hours 25 min

  • Sassi di Matera
  • Casa Grotta del Casalnuovo
  • Trulli di Alberobello Puglia
  • Colonne Romane
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Wake up to day 2 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Matera, Alberobello, and Brindisi. With 1 night to stay in Brindisi, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Matera is brimming with adventures.

Sassi Di Matera is must-visit archeological site and a great option for a daytime tour of the area. Continue your journey to Casa Grotta Del Casalnuovo, an increasingly popular cave, located just a leisurely stroll away. Next, head to Trulli Di Alberobello Puglia, an UNESCO world heritage-designated historical landmark, also available for your discovery today.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Brindisi.

Indulge in a memorable dining experience at one of Brindisi's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bento? It's another excellent option with a diverse menu. Consider reserving a table at Cozza Nera as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Brindisi.

Continue the enjoyment post-dinner at Altair Cafè, a cherished local gathering spot renowned for its welcoming atmosphere.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day3

Day 3

  • Brindisi
  • Sorrento
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Drive 475 km, 7 hours 22 min

  • Chiesa di Santa Maria Assunta
  • Amalfi Coast
  • Villa Rufolo
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Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Positano, Amalfi, and Ravello. At the end of the day, you will retreat to the hotel of your choice in Sorrento, where will spend 1 night.

Chiesa Di Santa Maria Assunta is perfect for a self-paced visit during the day. This romantic church is sure to impress.

While exploring and sightseeing, take time to savor the culture of Brindisi by sampling some local delicacies. When you’re ready for more sightseeing, head to Villa Rufolo. This visually striking historical landmark is an essential place to visit for anyone looking for the full Brindisi experience.

When you’re done exploring for the day, you’ll drive to your hotel in Sorrento. Check in and relax before you head out to tour the town.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Sorrento, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Frankie's Pizza Bar Sorrento Brunch & Vegan, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bougainvillea? It's another excellent option with a diverse menu. Consider reserving a table at Banana Split as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Sorrento.

Keep the excitement of the evening going by visiting a bar or two. Leone Rosso Café is an excellent place to start. You could also check out Hotel Antiche Mura Sorrento, offering a different kind of charm.

Savor another day of unforgettable experiences in Italy!

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Day4

Day 4

  • Sorrento
  • Rome
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Drive 293 km, 4 hours 35 min

  • Archaeological Park of Pompeii
  • Mount Vesuvius
  • Piazza Navona
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On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, including Pompei, Ottaviano, and Rome. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 1 night.

Archaeological Park Of Pompeii brings Sorrento's character to life. This breathtaking archeological site is a highlight of any visit in the town. Then, enjoy Mount Vesuvius, another picturesque attraction that never fails to captivate visitors. Next, head over to Piazza Navona, one of the town’s most timeless attractions, known for its visually striking features.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Unwind after your meal by stepping into La Botticella Of Poggi Giovanni. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Almalu Trastevere offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Viminale Di Pepi Maurilio, another top-rated bar in the area.

Relax and recharge in preparation for another adventurous day in Italy!

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Day5

Day 5

  • Rome
  • Brindisi
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Drive 623 km, 6 hours 40 min

  • Pantheon
  • Trevi Fountain
  • Spanish Steps
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Your itinerary for day 5 of your road trip in Italy includes 1 stop and features some of the highlights of Rome. At the end of the day, enjoy the comforts of a top-rated hotel in Brindisi, where you'll spend 1 night.

One of the most world-famous attractions included on the itinerary is Pantheon. This photogenic monument will help you start your sightseeing on top. Then, take a leisurely stroll to Trevi Fountain and learn what makes this visually striking monument unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the impressive Spanish Steps.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Brindisi. Brindisi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Brindisi. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Rendez-Vous Cafè Bistrot, a highly-rated dining destination in Brindisi. If you're eager to try something different, consider Pizzeria La Nassa, another top spot with a tantalizing menu. You might also want to secure a reservation at Birreria 64. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Brindisi this evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day6

Day 6

  • Brindisi - Departure day
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  • Palazzo Granafei Nervegna (Brindisi)
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Palazzo Granafei Nervegna (brindisi). This frequently visited palace is a hotspot among locals.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

Treat yourself to a delicious dinner at Supermercato Famila, an excellent option for tonight's dining. Looking for something different? Break24 offers a tantalizing alternative with its diverse menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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How it works

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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