6-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Sorrento and Rome

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Experience the freedom of the open road in Italy as you embark on an unforgettable 6-day road trip! This experience caters to every traveler, featuring destinations like Brindisi, Matera, Alberobello, Positano, Amalfi, Ravello, Sorrento, Pompei, Ottaviano, and Rome.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Brindisi, 1 night in Sorrento, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Pantheon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Navona, learn more about the unique Amalfi Coast, and immerse yourself in the vibrant atmosphere of Spanish Steps.

As you hit the open road and drive through Brindisi, Matera, Alberobello, Positano, Amalfi, Ravello, Sorrento, Pompei, Ottaviano, and Rome, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Swabian Castle of Brindisi
Sassi di MateraCasa Grotta del CasalnuovoTrulli di Alberobello PugliaColonne Romane
Chiesa di Santa Maria AssuntaAmalfi CoastVilla Rufolo
Archaeological Park of PompeiiMount VesuviusPiazza Navona
PantheonTrevi FountainSpanish Steps
Palazzo Granafei Nervegna (Brindisi)

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Swabian Castle of Brindisi
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Welcome to Brindisi, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Brindisi's charm before embarking on the next leg of your journey.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Swabian Castle Of Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Brindisi. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Bracerie Escosazio, an iconic dining spot in Brindisi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Penny, a popular restaurant in Brindisi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Piadineria, a hidden gem nestled in Brindisi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse stands out as an excellent choice for a post-dinner cocktail. Alternatively, Eden Cafè offers an ideal atmosphere to enjoy the pleasures of the night.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
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Drive 305 km, 4 hours 25 min

  • Sassi di Matera
  • Casa Grotta del Casalnuovo
  • Trulli di Alberobello Puglia
  • Colonne Romane
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At the end of the day, you'll drive back to Brindisi, where you'll stay for 1 night more.

Brace yourself for today’s incredible lineup of attractions in Brindisi, featuring fun adventures, romantic experiences, and breathtaking views. Start at Sassi Di Matera, a popular archeological site in the city. Then, head to Casa Grotta Del Casalnuovo and soak in the ambiance of this breathtaking cave.

There are many interesting places to see in Brindisi, and when you are ready for more, go to Trulli Di Alberobello Puglia. This is one of the city’s most interesting respected spots of interest. After exploring the historical landmark, visit the increasingly popular End Of The Via Appia Antica.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Brindisi.

As dinnertime approaches, it's time to head out for a bite to eat in Brindisi. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an excellent option for tonight's dining. Looking for something different? Bento offers a tantalizing alternative with its diverse menu. And don’t miss Cozza Nera. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Brindisi.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Altair Cafè, known for its inviting atmosphere.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 3

Day 3

  • Brindisi
  • Sorrento
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Drive 475 km, 7 hours 22 min

  • Chiesa di Santa Maria Assunta
  • Amalfi Coast
  • Villa Rufolo
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On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Positano, Amalfi, and Ravello. In the evening, you’ll end up in Sorrento, where you will stay for 1 night.

Start your day with a visit to Chiesa Di Santa Maria Assunta. This increasingly popular church is a must-visit in the village.

One of the best things about exploring Brindisi on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Villa Rufolo, a notable historical landmark in the village.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Sorrento. Sorrento offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Sorrento, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Frankie's Pizza Bar Sorrento Brunch & Vegan, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bougainvillea? It's another excellent option with a diverse menu. Consider reserving a table at Banana Split as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Sorrento.

Round off your dining experience by visiting Leone Rosso Café, a prime location for a drink. Alternatively, explore the distinctive characteristics of Hotel Antiche Mura Sorrento, a bar catering to every mood and preference.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 4

Day 4

  • Sorrento
  • Rome
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Drive 293 km, 4 hours 35 min

  • Archaeological Park of Pompeii
  • Mount Vesuvius
  • Piazza Navona
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On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, Pompei, Ottaviano, and Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.

Today’s route brings family-friendly attractions, breathtaking views, and picturesque spots. The first attraction of today is Archaeological Park Of Pompeii. This notable archeological site is an UNESCO world heritage-listed place to see in Sorrento. Continue your discovery at Mount Vesuvius, a history-steeped volcano with stories to tell.

As you stroll around Sorrento, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Piazza Navona. This timeless public square offers a visually striking encounter with Sorrento. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Sorrento.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at La Bottega Roma, a top recommendation for dinner tonight. Or, for a change of pace, Pasta In Corso boasts a menu that's sure to impress. Also, be sure to check out Trattoria Vecchia Roma. Known as a local hotspot, it’s a great choice for tonight in Rome.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 5

Day 5

  • Rome
  • Brindisi
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Drive 623 km, 6 hours 40 min

  • Pantheon
  • Trevi Fountain
  • Spanish Steps
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Dive into day 5 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Brindisi. You’ll stay here for 1 night.

Get ready for an exciting day in Rome. Today’s sightseeing agenda includes a monument and a public square. Begin your adventure at Pantheon. This is a globally renowned monument you should not miss. Another must-see is Trevi Fountain, an iconic monument in Rome.

When you’re ready for the next sight, head to Spanish Steps.

At the end of the day, you will drive to Brindisi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Brindisi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Rendez-Vous Cafè Bistrot, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Pizzeria La Nassa is another top choice with a popular menu. You could also check for a table at Birreria 64. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Brindisi tonight.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 6

Day 6

  • Brindisi - Departure day
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  • Palazzo Granafei Nervegna (Brindisi)
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Palazzo Granafei Nervegna (brindisi). This increasingly popular palace is a popular place to see in the city.

Maximize your last day in Italy and go on a shopping spree in Brindisi’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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