6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina

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Photo of Palermo, Sicily, Italy. Seafront view.
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Description

Escape the ordinary with this exciting 6-day road trip through Sicily. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Palermo, 1 night in Agrigento, and 2 nights in Taormina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Agrigento, Piazza Armerina, Taormina, Catania, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Welcome to Palermo, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Palermo before embarking on the next leg of your journey.

Palermo is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Palermo. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 6-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
  • Agrigento
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Drive 138 km, 2 hours 53 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Valle dei Templi
  • More

Your itinerary for day 2 of your road trip in Sicily includes 2 stops and features some of the highlights of Palermo and Agrigento. At the end of the day, enjoy the comforts of a top-rated hotel in Agrigento, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Agrigento. Agrigento offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Agrigento's most popular restaurants, and connect with friendly locals for a true cultural experience.

As the sun sets, rest up and recharge for the next leg of your road trip in Sicily.

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Day 3

Day 3

  • Agrigento
  • Taormina
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Drive 248 km, 4 hours 17 min

  • Villa Romana del Casale
  • Isola Bella
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • Porta Catania
  • More

On day 3 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 3 destinations, including Piazza Armerina, Mazzarò, and Taormina. When you’re not sightseeing, take time to relax at your chosen hotel in Taormina, where you’ll be staying for 2 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Taormina. Check in and relax before you head out to tour the town.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Taormina, it's often a good idea to reserve a table in advance.

Raise your glass to another unforgettable day in Sicily!

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Day 4

Day 4

  • Taormina
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Drive 108 km, 1 hour 59 min

  • Castello Ursino
  • Greek - Roman theatre
  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Piazza Università
  • Villa Bellini/Chiosco Bellini
  • More

On day 4 of your road trip, you’ll start and end your day in Taormina, where you have 1 night left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Taormina.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Taormina. Enjoy a relaxing evening as you savor delicious local cuisine.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day 5

Day 5

  • Taormina
  • Palermo
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Drive 281 km, 3 hours 58 min

  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Porta della Pescara (Porta Marina)
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Cefalù Beach
  • More

Experience an unparalleled adventure on day 5 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Cefalù. At the end of the day, you will retreat to the hotel of your choice in Palermo, where will spend 1 night.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Palermo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day 6

Day 6

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
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Day 6 of your road trip in Sicily is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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