6-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Portofino and Florence

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Genoa and San Fruttuoso di Camogli. When you’re not sightseeing, take time to relax at your chosen hotel in Portofino, where you’ll be staying for 2 nights.

Visiting Piazza De Ferrari is always a good idea. This notable public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the respected wonders of Genoa Cathedral, a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Doge's Palace. This worthwhile museum offers an enriching experience. For a change of pace, head to Aquarium Of Genoa, where you can take in stunning features. Conclude your self-guided sightseeing tour with a visit to Lighthouse Of Genoa These sights offer a fulfilling end to a perfect day.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to San Fruttuoso di Camogli may take around 55 min. Upon your arrival in San Fruttuoso di Camogli, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Our first attraction recommendation in San Fruttuoso di Camogli is Area Marina Protetta Di Portofino, an increasingly popular nature reserve that draws attention for its eye-catching features.

At the end of the day, you will drive to Portofino, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Portofino. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Trattoria Concordia, an iconic dining spot in Portofino. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Da Ö Batti Portofino - Ristorante Da Ö Batti, a popular restaurant in Portofino. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Puny, a hidden gem nestled in Portofino. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Celebrate another amazing day of your road trip adventure in Italy!

On day 3 of your road trip, you’ll start and end your day in Portofino, where you have 1 night left to stay.

Embrace the thrill of the open road as you wave goodbye to Portofino and set your GPS to Manarola. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 44 min. Upon reaching Manarola, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Manarola Overlook Viewpoint and explore the awe-inspiring features.

Fasten your seatbelt and make your way to your next stop — Corniglia, home to many well-known sights in the region. Keep in mind that your travel time from Manarola to Corniglia may take around 15 min without traffic disruptions. Upon arrival in Corniglia, we highly recommend checking out some of the top attractions.

For a more meaningful self-guided tour of the village's best attractions, visit Cinque Terre National Park, an interesting national park that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Scalinata Lardarina and admire its visually striking features.

Fasten your seatbelt and make your way to your next stop — Vernazza, home to many well-known sights in the region. Upon arrival in Vernazza, we highly recommend checking out some of the top attractions.

Set out on a self-guided sightseeing tour at Ruins Of Doria Tower and explore the culturally significant features.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Portofino.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Portofino, it's often a good idea to reserve a table in advance.

Dine in style at I Gemelli, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Taverna del marinaio boasts a menu that's sure to impress. Also, be sure to check out Ristorante Lo Stella. Known as a local hotspot, it’s a great choice for tonight in Portofino.

Celebrate another amazing day of your road trip adventure in Italy!

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pisa and Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Portofino and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 52 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you're ready for some sights, head to Leaning Tower Of Pisa, an iconic monument in Pisa. Explore its detailed features at your own pace before you continue your journey to your next attraction, Piazza Del Duomo, Pisa. This globally renowned public square is a top recommendation in the area.

When you’re ready to explore more, Porta Nuova is an excellent choice. Spend some time discovering what some claim to be the most photogenic monument in the region.

After soaking in Pisa’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Florence. Expect your car journey to take a minimum of 1 hour 16 min. When you arrive in Florence, it's time to take a break from the road.

For a more meaningful self-guided tour of the city's best attractions, visit Uffizi Gallery, an astonishing art gallery that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Ponte Vecchio and admire its romantic features.

When you’re ready, continue to Piazza Della Signoria, a top-rated public square beloved by locals and tourists alike.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Il Vinile likewise offers a unique atmosphere, perfect for a memorable night out.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Florence, Greti, and San Gimignano. At the end of the day, you will retreat to the hotel of your choice in Genoa, where will spend 1 night.

Basilica Of Santa Croce In Florence makes a great addition to your morning plans. This popular church is a heritage-rich place to see in Florence.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Florence.

When you’ve had your share of Florence, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Greti. Your travel time is around 38 min.

One of our top recommendations for your sightseeing is Villa Calcinaia - Conti Capponi. Spend some time admiring the respected features of the winery before you continue to your next stop.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in San Gimignano. This drive usually takes around 49 min, without any stops or traffic disruptions.

Spend your afternoon discovering Porta San Giovanni, a curiosity-inducing monument known for its UNESCO world heritage-designated features. Next, continue your sightseeing at Sangimignano1300, an increasingly popular museum.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Piazza Del Duomo and uncover the details of this majestic public square.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and relax before you head out to tour the city.

Genoa is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Genoa.

Savor the flavors at Zeffirino, a top pick for dinner tonight. Alternatively, Trattoria Vegia Zena beckons with its unique menu offerings. Also, consider Trattoria delle Grazie. With its consistent customer satisfaction, it’s an excellent option for dining in Genoa tonight.

Say good night to Genoa and look forward to another great day of your road trip in Italy!