6-Day Italy Self-Drive Road Trip With Itinerary from Perugia to Florence

Wake up to day 2 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Perugia and Santa Maria degli Angeli. With 1 night to stay in Perugia, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Visiting Rocca Paolina is always a good idea. This frequently visited historical landmark is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the photogenic wonders of National Archaeological Museum Of Umbria, a must-see museum in the city.

Continue your road trip and head to your next destination, Santa Maria degli Angeli. This car ride takes around 27 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Basilica Of San Francesco D'assisi, an interesting church that everyone visiting Santa Maria degli Angeli should see. Next, head to Piazza Del Comune. This enchanting public square is one of the most frequently visited attractions in the region.

If you're keen to see more, don’t miss out on Basilica Di Santa Chiara, a majestic church popular among locals as well as travelers. Mount Subasio is an excellent attraction to visit next. Spend some time learning more about this curiosity-inducing mountain range before you continue your journey.

When you’re done exploring for the day, you’ll return to Perugia and your accommodation.

Indulge in a memorable dining experience at one of Perugia's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at La Taverna, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante del Sole, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Al Mangiar Bene, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Caffè Fortebraccio, a well-loved spot among locals and tourists. Or, head to Caffe Del Banco. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Dempsey's Perugia, another top-rated place in the area.

Relax and recharge in preparation for another adventurous day in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Florence. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 2 nights.

Florence’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Perugia behind. This drive usually takes around 1 hour 49 min. Florence welcomes you with a multitude of unique vacation experiences.

Savor the day by heading to Piazzale Michelangelo, an impressive observation deck that draws visitors from near and far. When you're done, continue to Basilica Of Santa Croce In Florence, where you can soak in the heritage-rich surroundings.

Next, explore Uffizi Gallery, yet another spectacular place to see in the area. After the art gallery, make time to go to Ponte Vecchio. This visually striking historical landmark is well worth the visit. Lastly, head to Cathedral Of Santa Maria Del Fiore, a top-rated church you won’t want to miss.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Extend your evening after a delightful meal by visiting Manifattura, which offers the perfect atmosphere for a night out. Moreover, Se·sto On Arno Rooftop Bar is another popular option for a drink or two. Likewise, Il Vinile also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Greet day 4 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Florence, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Pisa and Lucca.

Fasten your seatbelt and make your way to your next stop — Pisa, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Pisa may take around 1 hour 16 min without traffic disruptions. Upon arrival in Pisa, we highly recommend checking out some of the top attractions.

Savor the day by heading to Piazza Del Duomo, Pisa, an iconic public square that draws visitors from near and far. When you're done, continue to Leaning Tower Of Pisa, where you can soak in the UNESCO world heritage-designated surroundings.

Embrace the thrill of the open road as you wave goodbye to Pisa and set your GPS to Lucca. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 32 min. Upon reaching Lucca, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Our first attraction recommendation in Lucca is Piazza Dell'anfiteatro, a popular public square that draws attention for its enchanting features. Spend some time soaking in the atmosphere before continuing to San Michele In Foro, a picture-perfect church that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Porta San Pietro, an up-and-coming monument that offers a unique experience. Be sure to also explore Mura Di Lucca, a nearby historical landmark, highly recommended by other travelers.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Bar 50 Rosso, known for its lively atmosphere. Bitter Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Archea Brewery offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in Italy!

Your itinerary for day 5 of your road trip in Italy includes 2 stops and features some of the highlights of Siena and San Gimignano. At the end of the day, enjoy the comforts of a top-rated hotel in Perugia, where you'll spend 1 night.

As you explore Siena’s charming streets, take in the lively atmosphere and get to know the character of the city.

When you’ve had your share of Florence, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Siena. Your travel time is around 1 hour 10 min.

Spend your afternoon discovering Fortezza Medicea (siena), an up-and-coming monument known for its culturally significant features. Next, continue your sightseeing at Tower Of Mangia, an often recommended monument.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Piazza Del Campo and uncover the details of this romantic public square. Make sure to also explore Siena Cathedral, a notable church.

San Gimignano’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Siena behind. This drive usually takes around 49 min. San Gimignano welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Chiesa Di Sant'agostino, a worthwhile church known for its instagrammable features. Next, continue your sightseeing at Piazza Del Duomo, a locally appreciated public square.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Perugia is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Perugia.

Make sure to reserve a table at Perugia Plaza Hotel, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Elfo Pub Perugia, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sangallo Palace Hotel, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the excitement of the evening going by visiting a bar or two. Il Birrino is an excellent place to start. You could also check out Quei Bravi Ragazzi, offering a different kind of charm. A last recommendation for the day is Lo Chalet - Lounge Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Get a good night's sleep and look forward to another great day on the road in Italy!