6-Day Italy road trip from Rome to Florence and Perugia

Your road trip adventure in Italy begins as soon as you reach the incredible city of Rome. You’ll stay in Rome for 3 nights, experiencing all the best things to do and see in the city.

Rome has many popular destinations you can explore. You could visit attractions like the incredible Altare della Patria. This attraction is an architectural structure and has an average rating of 4.8 out of 5 stars by 49,843 visitors.

When you're done sightseeing for the day, you'll check in at one of the best hotels or places to stay in the city. Your stay promises to be a delightful continuation of your exploration, providing comfort and tranquility to recharge for the adventures that lie ahead.

When you’re ready for dinner, we recommend you try one of the best restaurants in the city of Rome, 433. The restaurant is rated an average of 4.4 out of 5 stars by 2,341 customers.

Another of the best restaurants in the city of Rome is Roma Sparita. This restaurant is rated an average of 4.4 out of 5 stars by 2,073 customers.

Rome also has several great bars that will fit all travel budgets. One of the best bars in the city of Rome is D’Angelo Caffè & Gastronomia - Bar Bistro Caffetteria Napoletana a Roma. This bar has an average rating of 4.7 out of 5 stars by 1,054 customers.

Another of the best bars in the city of Rome is Cantina e Cucina. This bar is rated an average of 4.6 out of 5 stars by 7,907 customers.

Locals also enjoy Ai Tre Scalini. This bar has an average rating of 4.4 out of 5 stars by 2,950 customers.

Enjoy toasting the start of your 6-day vacation in Italy!

Day 2 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

There are plenty of attractions, markets, and restaurants for you to experience today in the city of Rome. Your accommodation will be conveniently located close to several of the best attractions you won't want to miss.

You'll be able to visit more of the best travel destinations in the city of Rome, like the extraordinary Colosseum. This attraction is a roman amphitheatre and has an average rating of 4.7 out of 5 stars by 328,821 visitors. Colosseum gets around 7,400,000 visitors every year.

Another of the best travel destinations in Rome is the spectacular Roman Forum. This attraction is a square and is rated an average of 4.7 out of 5 stars by 114,450 visitors.

You could then travel to the amazing Pantheon. This roman temple has an average rating of 4.8 out of 5 stars by 189,682 visitors. Up to 30,000,000 people visit this popular attraction every year.

Piazza Navona is another stop you might want to add to your itinerary. This square is a popular destination among visitors in Rome. Rated at an average of 4.7 out of 5 stars by 158,771 visitors, it’s one many travelers find worthy a visit.

If you’re interested in seeing something outstanding today, then consider Castel Sant'Angelo. Castel Sant'Angelo is a museum and popular attraction in Rome. More than 72,431 visitors have rated this place an average of 4.7 out of 5 stars. If you visit this attraction, you’ll be one of 918,591 people who do so each year.

Your discovery of Rome does not have to stop there. Check out the fantastic selection of tours and tickets offered in Rome on this day of your trip.

After a long day of exploring some of the most popular attractions in Italy, be sure to eat at Ristorante Amedeo, which is considered one of the best restaurants in the city of Rome. This restaurant is a local favorite and has an average rating of 4.3 out of 5 stars by 1,798 customers.

Alternatively, another of the top restaurants in the city of Rome is the popular La Taverna dei Fori Imperiali. This restaurant is rated an average of 4.4 out of 5 stars by 1,637 customers.

Another great restaurant we recommend in the city of Rome is Maccheroni. This restaurant has an average rating of 4.3 out of 5 stars by 1,633 customers.

When you’ve finished your meal, VinAllegro is one of the best bars in the city of Rome for an after-dinner drink. This bar has an average rating of 4.3 out of 5 stars by 1,167 customers.

Ristorante Tema is another of the most popular bars in the city of Rome. This bar is rated an average of 4.4 out of 5 stars by 939 customers.

Alternatively, a great bar that locals enjoy in the city of Rome is Bar Tornatora Rome. Bar Tornatora Rome has an average rating of 4.3 out of 5 stars by 952 customers.

Stopping at one of these popular bars is the perfect way to celebrate another incredible day in the magical city of Rome!

Day 3 of your road trip through Italy gives you the opportunity to experience two places in one day. You'll start your day with some exploring in the city of Rome and end it at a top-rated hotel in the city of Florence. You will stay in Florence for 1 night. Have a hearty breakfast and get excited for a wonderful day ahead!

One of the best places to visit today in Rome is the amazing Trevi Fountain. This attraction is a sculpture that is rated an average of 4.8 out of 5 stars by 343,494 visitors.

You could also stop at the incredible square, Piazza di Spagna. With an average rating of 4.7 out of 5 stars by 113,658 visitors, this attraction is one of the top sights in the area.

Another unforgettable travel destination in the Rome is the outstanding Spanish Steps. This popular monumental staircase and travel destination has an average rating of 4.5 out of 5 stars by 57,211 visitors.

The spectacular piazza del Popolo is another popular attraction you can visit today. This fascinating square and attraction has an average rating of 4.6 out of 5 stars from 89,807 visitors.

If you’re keen to explore even more, then consider a visit to the fantastic Villa Borghese. This attraction is a popular urban zone of rome that has an average rating of 4.6 out of 5 stars from 69,749 visitors.

You can make the most of your new day in Rome by joining activities and tours that let you discover what else the city has in store for you. There are many top-rated experiences you can include in your travel plan to add flavor to your road trip in Italy. Browse all of your options and reserve your slot before it's too late.

At the end of the day, you will drive to the city of Florence, where you will access the best hotels and places to stay.

After a long day of driving and exploring, we recommend you try Ristorante Paoli, one of the best restaurants in the city of Florence. This restaurant has an average rating of 4.9 out of 5 stars by 6,031 customers.

Locals also recommend Ristorante Oliviero 1962 as one of the best restaurants in the city of Florence. Ristorante Oliviero 1962 is rated an average of 4.7 out of 5 stars by 1,046 customers.

Another of the best restaurants in the city of Florence is Il Vezzo. This restaurant has been rated an average of 4.8 out of 5 stars by 862 customers.

After dinner, visit Manifattura, which is considered one of the best bars in the city of Florence. This bar is rated an average of 4.7 out of 5 stars by 509 customers.

You can also enjoy drinks at a popular bar like Ditta Artigianale. This bar has an average rating of 4.3 out of 5 stars by 1,877 customers.

Alternatively, Archea Brewery is one of the best bars that locals recommend in the city of Florence. This bar is rated an average of 4.7 out of 5 stars by 723 customers.

Raise your glass in celebration of your incredible road trip adventure through Italy!

As you rise to greet the dawn on day 4 of your epic road trip in Italy, you'll awaken to the bustling city of Florence. Today, you'll hit the road once again, setting off on a journey towards the stunning city of Perugia. You’ll stay in Perugia for 1 night. But before you begin your drive, we recommend taking the time to explore some of Florence’s must-see attractions and local hotspots.

If you’re curious to see more of Florence, start your day with a visit to the amazing piazza della Signoria. This much-appreciated square and attraction is rated 4.8 out of 5 stars by 66,956 visitors.

You could also stop at another of the best local travel destinations in the area, the fascinating Cathedral of Santa Maria del Fiore. This church and spectacular attraction has an average rating of 4.8 out of 5 stars from 76,359 visitors.

We also recommend you spend some time at the popular Ponte Vecchio to make the most of your road trip across Italy. The spectacular Ponte Vecchio is a deck arch bridge that has been rated an average of 4.7 out of 5 stars by 118,099 visitors.

The lovely Uffizi Gallery is yet another attraction you could pay a visit. Around 61,794 visitors have left this national museum average ratings of 4.7 out of 5 stars. This popular attraction gets around 2,011,219 visits every year.

If you feel like visiting another type of sight or don’t want to jump into the car quite yet, spend some time at the spectacular piazzale Michelangelo. This attraction is a square rated an average of 4.8 out of 5 stars in 77,744 reviews.

After soaking up all the sights and sounds that Florence has to offer, you'll be ready to hit the open road and continue your unforgettable road trip towards the city of Perugia. Perugia offers plenty of options for top-rated hotels and other places to stay that fit all travel budgets.

After you’ve settled into your accommodation, we recommend a dinner at the popular Al Mangiar Bene. This popular restaurant is one of the locals’ most recommended restaurants in the city, with ratings of 4.5 out of 5 stars in 1,395 reviews.

The remarkable La Prosciutteria Perugia is another top restaurant in Perugia we recommend. This restaurant offers an unforgettable dining experience and is rated an average of 4.6 out of 5 stars by 407 customers.

If you would rather go somewhere else, the famous Alphaville is also an excellent choice. This well-loved restaurant is rated an average of 4.7 out of 5 stars by 325 customers.

After your meal, we recommend you drink at one of the best bars in Perugia, the fantastic Quei Bravi Ragazzi. This bar has an average rating of 4.7 out of 5 stars by 543 customers.

To end your night the best way possible, we recommend going to the wonderful Elfo Pub Perugia. This bar offers a great variety of drinks and has been rated an average of 4.6 out of 5 stars by 754 customers.

Another bar with a great atmosphere is Punto di Vista. This bar is rated an average of 4.5 out of 5 stars by 502 customers, so don’t forget to check this one out as well!

Celebrate another amazing vacation day filled with adventure in Italy!

Rise and shine on day 5 of your road trip in Italy. Today, you'll wake up in Perugia and embark on a scenic drive to Rome, where you'll stay at one of the best hotels for 1 night. Seize the opportunity to explore spectacular attractions in Perugia and Vatican before you reach your end destination for the day.

It’s hard not to feel excited about visiting attractions in a destination as lovely as Perugia. When you’re eager to explore the city and nearby areas, we recommend visiting some local favorites, such as the wonderful Piazza IV Novembre. This attraction is a square that has an average rating of 4.6 out of 5 stars from 9,189 visitors.

You could also stop at the incredible Rocca Paolina. This attraction, a beloved rocca, has an average rating of 4.7 out of 5 stars from 7,128 visitors.

If you have time, another site you could explore in Perugia is the stunning Carducci Gardens. This park and travel destination has an average rating of 4.5 out of 5 stars by 1,768 visitors.

One of the most popular attractions you can visit is the remarkable Vatican Museums. This attraction is an art museum that has an average rating of 4.6 out of 5 stars from 133,310 visitors. Around 1,612,530 people visit Vatican Museums every year.

If you want to explore more, visit the incredible Saint Peter's Square. This square and attraction has an average rating of 4.8 out of 5 stars from 38,954 reviews.

Another site you could visit today is the top-rated Sistine Chapel. This chapel and travel destination is rated an average of 4.7 out of 5 stars by 52,083 visitors.

The lovely St. Peter's Basilica is yet another attraction you could pay a visit. Around 131,043 visitors have left this major basilica an average rating of 4.8 out of 5 stars. This popular attraction gets around 11,000,000 visits every year.

When you're done with your sightseeing in Vatican, it's time to continue your drive to the city of Rome. When you arrive in Rome you’ll check in at one of the best hotels in the area.

We recommend you end the day with a dinner at a popular restaurant near your accommodation, like Coso Ristorante. This restaurant offers various delicious and comforting meals and has an average rating of 4.3 out of 5 stars from 1,275 customers.

Locals also recommend Pierluigi, another of the best restaurants in Rome. Pierluigi is rated an average of 4.3 out of 5 stars by 1,123 customers.

If you feel like having something else, check out the menu at Ristorante Ad Hoc. This restaurant has been rated an average of 4.6 out of 5 stars by 752 customers and is a great place to enjoy a lovely meal.

After dinner, visit La Botticella of Poggi Giovanni to enjoy a couple of drinks and relax. This bar is one of the best in Rome, with an average rating of 4.7 out of 5 stars by 655 customers.

You can also enjoy drinks at a popular bar like Tigelleria Romana - Bistrot & Cafè. This bar is a great spot to meet new friends and celebrate your vacation. Tigelleria Romana - Bistrot & Cafè has an average rating of 4.3 out of 5 stars by 792 customers.

La Licata is another bar locals often recommend. This bar offers a great variety of snacks and drinks and is rated an average of 4.5 out of 5 stars by 2,067 customers.

End your day by raising your glass in celebration of your incredible road trip adventure in Italy, and look forward to more great days to come!

Day 6 of your road trip in Italy is your departure day. This is your chance to catch one last glimpse of Rome before saying goodbye to this wonderful destination. When you have time to explore the area before you make your way home, we recommend visiting some of the following attractions.

Campo de' Fiori is an extraordinary attraction you could visit to enjoy your last day in Rome. This square and popular site of interest has an average rating of 4.4 out of 5 stars by 51,133 visitors.

Take a stroll along the main shopping streets of Rome and find some souvenirs to remind you of your road trip in Italy.

You could then enjoy your last meal in the city of Rome at Antica Pesa before you travel home. This popular restaurant is rated an average of 4.4 out of 5 stars by 858 customers.

Alternatively, we also recommend Hostaria Isidoro for your last chance at a meal in the city of Rome. The Hostaria Isidoro restaurant has an average rating of 4.3 out of 5 stars by 909 customers.

You’ll then say farewell to Rome. We wish you a pleasant journey home, with many wonderful memories of your unforgettable vacation in Italy!