Relaxed 7-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Rome

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Photo of Bright summer view from flying drone of Cattedrale di San Ciriaco church and San Gregorio Illuminatore - Catholic church. Stunning morning cityscape of Ancona town, Italy, Europe.
Photo of the long staircase in the downtown of the beautiful ancient italian village.
Relaxed 7-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Rome
Relaxed 7-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Rome
Relaxed 7-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Rome
Relaxed 7-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Rome
Relaxed 7-Day Italy Self-Drive Road Trip With Itinerary from Ancona to Rome
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Set out on this 7-day relaxed road trip in Italy, where Ancona, Loreto, Serra San Quirico, and Rome offer rich culture, beautiful views, and memorable experiences at every stop!

Travel freely with this relaxed self-drive package in Italy, designed for comfort and exploration. Spend 2 nights in Ancona and 4 nights in Rome, staying at top-rated hotels near the heart of each city. Between drives, indulge in local cuisine, sip refreshing drinks, and enjoy the vibrant atmosphere at popular restaurants and bars along your road trip route in Italy.

Your journey starts in Ancona, where your rental car with CDW insurance will be ready for pickup. Choose a vehicle that suits your style, then set off on your 7-day relaxed road trip in Italy to explore its rich culture, fascinating history, and stunning landscapes.

Every stop on this leisurely self-drive holiday comes with handpicked accommodations that make relaxation effortless. Choose from elegant 5-star hotels with breathtaking views or comfortable 3-star stays that offer excellent value, all providing a welcoming retreat after a day on the road.

With your self-drive itinerary in Italy already planned, you’ll enjoy the country’s most celebrated sights without the rush. Marvel at the stunning Trevi Fountain and soak in the atmosphere of the magnificent Colosseum.

Enjoy each stop as you explore the history, architecture, and character of each destination on this Italy road trip itinerary for 7 days.

As you travel between destinations, you’ll have plenty of time to explore local markets and boutique shops. These stops give you the chance to find unique souvenirs, taste regional specialties, and experience everyday life in Italy.

If you want to make your 7-day relaxed self-drive tour in Italy even more memorable, add optional tours or activities. Join a guided excursion, discover hidden neighborhoods, or spend an afternoon in your favorite market. Each choice deepens your connection to the places you visit.

Alongside these experiences, your laid-back self-drive package in Italy includes 6 nights in comfortable hotels, a rental car for 7 days, and convenient access to nearby dining options. You can also add flights and entry tickets to shape the trip exactly how you want it. With 24/7 travel support and a mobile app keeping your itinerary and documents organized, you can enjoy a relaxed drive and savor every mile of the road ahead.

Turn your travel plans into reality. Book your 7-day relaxed self-drive road trip in Italy today and enjoy a journey filled with discovery, freedom, and unforgettable moments!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Ancona - Arrival day
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  • Lazzaretto of Ancona
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Your relaxed road trip through Italy starts when you reach the incredible city of Ancona, where you'll stay for 1 night. You'll pick up your rental car in Ancona and begin your adventure in Italy.

Ancona is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Lazzaretto Of Ancona. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Ancona. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ancona, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Playa Solero, a top-rated dining destination in Ancona. If you're in the mood to try something new, consider Zucchero a Velò, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Il Giardino. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Ancona this evening.

As the day is coming to an end, stop at some of Ancona’s best bars to celebrate this day of your slow-paced adventure in Italy.

Extend your evening after a delightful meal by visiting Posa Bar, which offers the perfect atmosphere for a night out. Moreover, Bar Four Roses is another popular option for a drink or two. Likewise, Amarillo Beer Bar Ancona also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast as you look back on the highlights of today’s relaxed road trip in Italy. Enjoy your first taste of Ancona as you soak in the city’s unique vibe.

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Day2

Day 2

  • Ancona
  • Loreto
  • Serra San Quirico
  • Rome
  • More

Drive 366 km, 4 hours 44 min

  • Sanctuary of the Holy House of Loreto
  • Parco Naturale Regionale Gola della Rossa e di Frasassi
  • Frasassi Caves
  • More

On day 2 of your laid-back road trip adventure in Italy, you can visit several remarkable places. With the freedom and flexibility of a self-drive tour, you decide how much time to spend in each, making the most of these memorable destinations.

When you’re ready to jump back into the car and say goodbye to Ancona, you’ll hit the road in the direction of Loreto. This drive usually takes around 31 min.

Our first attraction recommendation in Loreto is Sanctuary Of The Holy House Of Loreto, a well-known church that draws attention for its breathtaking features.

Embrace the thrill of the open road as you wave goodbye to Loreto and set your GPS to Serra San Quirico. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 54 min. Upon reaching Serra San Quirico, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Parco Naturale Regionale Gola Della Rossa E Di Frasassi. Spend some time admiring the stunning features of the nature reserve before you continue to your next stop.

Continue your road trip and head to your next destination, San Vittore. This car ride takes around 13 min.

Savor the day by heading to Frasassi Caves, a well-known cave system that draws visitors from near and far.

In Rome, you’ll find plenty of places to unwind after a day on the road. Our top recommendations go perfectly with your laid-back road trip in Italy.

After a laid-back day of exploring top attractions in the area, it’s an excellent idea to sit down for a lovely and peaceful dinner. We’ve collected the most recommended restaurants in the city for you, so you can check out the menus and make your reservation in advance.

Discover the culinary delights of Rome by securing a reservation at La Pergola. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of mediterranean and contemporary cuisine. For an alternative dining experience, try Il Pagliaccio, renowned for its delicious creative and innovative dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Enoteca La Torre, a highly recommended local eatery celebrated for its mouthwatering mediterranean and creative menu. With its 2-star Michelin recognition, it offers an unforgettable dining adventure.

As the day is coming to an end, stop at some of Rome’s best bars to celebrate this day of your slow-paced adventure in Italy.

Extend your evening after a delightful meal by visiting La Botticella Of Poggi Giovanni, which offers the perfect atmosphere for a night out. Moreover, Almalu Trastevere is another popular option for a drink or two. Likewise, Bar Viminale Di Pepi Maurilio also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass in celebration of your freedom and relaxed road trip adventure in Italy!

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Day3

Day 3

  • Rome
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Drive 15 km, 53 min

  • Villa Borghese
  • Basilica di Santa Maria Maggiore
  • Colosseum
  • Roman Forum
  • Pantheon
  • More

On day 3 of your leisurely self-drive tour across Italy, you’ll go deep into Rome, where you'll stay for 3 nights, and see some of the city’s unforgettable attractions. To learn more of the city's culture, you'll also dine at the most popular restaurants in Rome, and meet locals along the way!

Villa Borghese leaves a lasting impression. This park is one of the most famous places to visit in Rome. Next, head to Basilica Di Santa Maria Maggiore, a locally renowned church, known for its culturally significant features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Colosseum. This breathtaking archeological site is a highly recommended experience. Nearby, you'll also find Roman Forum and Pantheon Visit these for an interesting touch to your journey.

Gain a one-of-a-kind experience on your unhurried and relaxed road trip across Italy by joining a traveler-approved tour in Ancona. There are so many fun and eye-opening activities to try out in Ancona that will make your slow-paced self-drive tour in Italy more memorable. Check out all the most recommended and top-rated tour options in the city of Rome to find the best options for you!

After a laid-back day of exploring top attractions in the area, it’s an excellent idea to sit down for a lovely and peaceful dinner. We’ve collected the most recommended restaurants in the city for you, so you can check out the menus and make your reservation in advance.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Take a stroll around the area, head back to your accommodation for the night, or continue your evening at one of the best-rated bars in the city.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

A leisurely self-drive holiday in Rome can’t get any better than this! Toast to another amazing day in Italy!

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Day4

Day 4

  • Rome
  • More

Drive 17 km, 55 min

  • Trevi Fountain
  • Piazza di Spagna
  • Spanish Steps
  • piazza del Popolo
  • Castel Sant'Angelo
  • More

Day 4 of your relaxed road trip through Italy means 24 hours of making the best memories in Rome. You’ll go sightseeing at famous attractions in Rome. In the evening, you will experience one of the most popular dining spots in the city. So buckle up and prepare to be blown away by Rome!

To truly experience Rome, make sure to drop by Trevi Fountain. This wondrous monument is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Piazza Di Spagna, one of the city’s best highlights.

Next, check out Spanish Steps, one of the most astonishing places to see in Rome. This public square is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazza Del Popolo. Wander around and soak in the enchanting atmosphere this public square offers. Then, head to Castel Sant'angelo, a top-rated castle that adds another dimension to your day.

Another way to make your easygoing and relaxed road trip in Italy more special is by joining unique tours and activities. Rome offers a wide selection of experiences for every traveler.

Mealtimes are the perfect opportunities to immerse yourself in the local culture of Italy. When you're not appreciating the best places to visit in Rome, explore the city like a local by trying out the best restaurants in the area.

Treat yourself to a wonderful meal at Hotel de Russie, a top-rated dining spot in Rome. If you're in the mood for something new, try La Taverna Italiana, another premier location with a delectable menu. You might also want to book a table at The Parrot Bar. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

A visit to a top-rated local bar is one of the most refreshing ways to cap off a beautiful night in Rome.

If you’re not ready to end the night just yet, The Apartment Bar Roma offers a perfect venue to relax and savor a drink. Similarly, Hotel Hassler Roma is well-suited for those looking to unwind in a social setting.

Toast to another unforgettable and relaxing road trip adventure in Italy!

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Day5

Day 5

  • Rome
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Drive 6 km, 26 min

  • Piazza Navona
  • Campo de' Fiori
  • largo di Torre Argentina
  • Altare della Patria
  • Circus Maximus
  • More

Day 5 introduces you to many popular attractions and activities in Rome, further proving that leisurely self-drive tours in Italy are extraordinary.

One of the most wondrous attractions included on the itinerary is Piazza Navona. This history-steeped public square will help you start your sightseeing on top. Then, take a leisurely stroll to Campo De' Fiori and learn what makes this historic public square unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the well-known Largo Di Torre Argentina. After exploring the archeological site, head to Altare Della Patria. This interesting monument is a highlight in Rome. As your day continues, stop by Circus Maximus, known for its culturally significant features.

Make the most of your time in the country by joining activities that let you discover more about Italy. Check out all of the tours you can join this day of your leisurely self-drive holiday in Italy and ensure the experience of a lifetime.

When it’s time to eat, the city has a variety of restaurants and cuisines to suit your palate and complement your relaxed road trip experience. Take a leisurely walk around Rome, while looking for a place to eat. Or, check out our top recommendations and treat yourself to a nice meal.

Enjoy a delicious meal at Sofitel Roma Villa Borghese, a highly-rated dining destination in Rome. If you're eager to try something different, consider Centro, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante Tema. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Hang out and unwind at some of the top bars in Rome.

Grab a drink and enjoy every passing minute of this night of your relaxed road trip experience in Italy!

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Day6

Day 6

  • Rome
  • Vatican City
  • Ancona
  • More

Drive 312 km, 3 hours 50 min

  • St Peter's Basilica
  • Sistine Chapel
  • Vatican Museums
  • More

Day 6 of your relaxed road trip across Italy offers a day of exciting discoveries. You’ll start your day in Vatican City and drive in the direction of Ancona for some laid-back sightseeing. You’ll end your day in Ancona, where you’ll stay for 1 night.

Fasten your seatbelt and make your way to your next stop — Vatican City, home to many well-known sights in the region. Keep in mind that your travel time from Rome to Vatican City may take around 11 min without traffic disruptions. Upon arrival in Vatican City, we highly recommend checking out some of the top attractions.

One of our top recommendations for your sightseeing is St. Peter's Basilica. Then, head to Sistine Chapel. This extraordinary chapel is a traveler-favorite in the city.

If you're keen to see more, continue to Vatican Museums. Feed your curiosity by learning something new about the art museum.

After a day of exploration, relax at one of the top hotels or accommodations in Ancona. Staying in the city gives you a comfortable, welcoming place to recharge during your laid-back road trip in Italy.

When you’re not driving and exploring some of the best places in Italy, it’s time to make your relaxed road trip even more comforting. Sit down for a lovely meal at one of the best restaurants in Ancona.

Experience a symphony of flavors at Sot'Ajarchi in Ancona by securing a reservation in advance. Renowned for its Bib Gourmand distinction, Sot'Ajarchi delights its guests with its exceptional variety of meals showcasing delicious seafood and from the marches cuisine. Or, if you're feeling adventurous, why not try Bontà delle Marche? It's another excellent option with a diverse menu.

Hang out and unwind at some of the top bars in Ancona.

After your meal, keep the night alive at a bar like Alla Tazza D'oro, known for its lively atmosphere.

A leisurely self-drive holiday in Vatican City can’t get any better than this! Toast to another amazing day in Italy!

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Day7

Day 7

  • Ancona - Departure day
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  • Passetto
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Day 7 of your relaxed road trip in Italy is your departure day. If you’re flying home, return your rental car with time to spare. For a stress-free farewell, book a later flight and enjoy a final, relaxed day in Ancona.

If you're up for some more sightseeing, we recommend visiting Passetto, a history-steeped monument before you head out.

Over a good meal, take a moment to unwind and reflect on the past 7 days of your relaxed road trip. Savor one last traditional dish in Ancona, or keep it light with a quick bite before you go.

If you're in the mood to try something new, consider Donegal Irish Pub, another top spot with a mouthwatering menu.

Give yourself enough time to wave goodbye to Ancona and begin your journey home. The unforgettable experiences you’ve collected along your 7-day relaxed road trip in Italy is a story you will tell for the rest of your life.

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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