Travel packages in Italy

Road trips in Italy

7-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Catania

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Photo of Palermo, Sicily, Italy. Seafront view.

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Experience the freedom of the open road on an unforgettable 7-day road trip in Sicily! Embark on a self-drive tour that caters to every traveler, featuring destinations like Palermo, Cefalù, Taormina, Catania, Syracuse, and Agrigento.

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 4 nights in Palermo and 2 nights in Catania. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Cefalù, Taormina, Catania, Syracuse, and Agrigento, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65

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Day 1

Palermo - Arrival day
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Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 3 nights before you continue your adventure!

Palermo is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 7-day road trip in Sicily!

Day 2

Palermo
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Drive 31 km, 1 hour 38 min

Norman Palace
Palermo Cathedral
Quattro Canti
Fontana Pretoria
Orto botanico di Palermo
Santuario di Santa Rosalia, Palermo
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You have 2 nights left in Palermo. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Say good night to Palermo and look forward to another great day of your road trip in Sicily!

Day 3

Palermo
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Drive 145 km, 2 hours 34 min

Castello di Cefalù
Rocca di Cefalù
Cathedral of Cefalù
Porta della Pescara (Porta Marina)
Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
Cefalù Beach
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On day 3 of your road trip, you’ll start and end your day in Palermo, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Cefalù.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Palermo.

After a day of adventure, treat yourself to an exquisite dinner at one of Palermo's best restaurants.

Celebrate another amazing day of your road trip adventure in Sicily!

Day 4

Palermo
Catania
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Drive 332 km, 5 hours 14 min

Chiesa Madonna della Rocca
Porta Catania
Basilica of St. Nicholas of Bari
Ancient theatre of Taormina
Villa Comunale di Taormina
Isola Bella
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Your itinerary for day 4 of your road trip in Sicily includes 2 stops and features some of the highlights of Taormina and Mazzarò. At the end of the day, enjoy the comforts of a top-rated hotel in Catania, where you'll spend 2 nights.

At the end of the day, you will drive to Catania, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Catania is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Catania.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

Day 5

Catania
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Drive 138 km, 2 hours 12 min

Ear of Dionysius
Neapolis Archaeological Park
Temple of Apollo
Fountain of Diana
Island of Ortigia
Cathedral of Syracuse
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On day 5 of your road trip, you'll get the chance to experience Syracuse. At the end of the day, you'll drive back to Catania, where you still have 1 night left to stay.

When you’re done exploring for the day, you’ll return to Catania and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Catania. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Head back to your accommodation in Catania and get some rest to prepare for another magical day of your road trip in Sicily.

Day 6

Catania
Palermo
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Drive 293 km, 4 hours 21 min

Tempio Di Zeus Olympios
Temple of Heracles
Valle dei Templi
Museo archeologico regionale Pietro Griffo
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On day 6 of your road trip in Sicily, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Agrigento are on today's agenda. In the evening, you’ll end up in Palermo, where you will stay for 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for a true cultural experience.

Relax and look forward to more memorable moments to come!

Day 7

Palermo - Departure day
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Catacombe dei Cappuccini
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Day 7 of your road trip in Sicily is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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