7-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Catania

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Experience the freedom of the open road in Sicily as you embark on an unforgettable 7-day road trip! This experience caters to every traveler, featuring destinations like Palermo, Cefalù, Taormina, Catania, Syracuse, and Agrigento.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 4 nights in Palermo and 2 nights in Catania. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Ancient Theatre Of Taormina, learn more about the unique Quattro Canti, and immerse yourself in the vibrant atmosphere of Norman Palace.

As you hit the open road and drive through Palermo, Cefalù, Taormina, Catania, Syracuse, and Agrigento, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Foro Italico
Norman PalacePalermo CathedralQuattro CantiFontana PretoriaOrto botanico di PalermoSantuario di Santa Rosalia, Palermo
Castello di CefalùRocca di CefalùCathedral of CefalùPorta della Pescara (Porta Marina)Lavatoio Medievale Fiume Cefalino - Cefalù (pa)Cefalù Beach
Chiesa Madonna della RoccaPorta CataniaBasilica of St. Nicholas of BariAncient theatre of TaorminaVilla Comunale di TaorminaIsola Bella
Ear of DionysiusNeapolis Archaeological ParkTemple of ApolloFountain of DianaIsland of OrtigiaCathedral of Syracuse
Tempio Di Zeus OlympiosTemple of HeraclesValle dei TempliMuseo archeologico regionale Pietro Griffo
Catacombe dei Cappuccini

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Day 1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 3 nights before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Cotto e Bollito, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bebop offers an enticing alternative with its varied menu. Additionally, Eremiti Restaurant is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Palermo.

To truly maximize your evening out, consider visiting Malox Cult after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Ai Giudici, another bar with an inviting ambiance. Similarly, Bar Italico also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 7-day road trip in Sicily!

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Day 2

Day 2

  • Palermo
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Drive 31 km, 1 hour 38 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Santuario di Santa Rosalia, Palermo
  • More

On day 2 of your road trip, you will have an entire day to explore Palermo. You’ll stay in Palermo for 2 nights and discover all the best things to see and do in the area.

Get ready for an exciting day in Palermo. Today’s sightseeing agenda includes a palace, a church, a public square, a monument, a botanical garden and much more! Begin your adventure at Norman Palace. This is a captivating palace you should not miss. Another must-see is Palermo Cathedral, a captivating church in Palermo.

When you’re ready for the next sight, head to Quattro Canti. From there, take a leisurely stroll to Fontana Pretoria, another of the city’s locally appreciated attractions. We recommend continuing your self-guided tour at Orto Botanico Di Palermo, a serene place of interest in the city. If time allows, add Santuario Di Santa Rosalia, Palermo to your itinerary. This up-and-coming church offers the perfect finishing touch to your day in Palermo.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Palermo's best restaurants.

Make sure to reserve a table at Osteria Mercede, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Del Massimo, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Grand Hotel Piazza Borsa, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to Spina Bar Palermo, ideal for a leisurely evening with a drink in hand. Torrefazione Castagnetta Massimiliano (gelateria) is another bar that offers an enjoyable setting. Similarly, Monkey Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Head back to your accommodation in Palermo and get some rest in preparation for another magical day of your road trip in Sicily!

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Day 3

Day 3

  • Palermo
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Drive 145 km, 2 hours 34 min

  • Castello di Cefalù
  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Porta della Pescara (Porta Marina)
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Cefalù Beach
  • More

On day 3 of your road trip, you’ll start and end your day in Palermo, where you'll stay for 1 night more.

Today’s agenda in Palermo includes a castle, a church, a historical landmark, a beach and much more! Castello Di Cefalù is must-visit castle and a great starting point for the day. Next, continue your journey to Rocca Di Cefalù, a frequently visited castle, located just a leisurely stroll away. Next, head to Cefalù Cathedral, a romantic church, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Palermo. When you're ready, let your sightseeing route take you to the increasingly popular Porta Pescara (porta Marina). If you’re looking for more, Lavatoio Medievale Fiume Cefalino - Cefalù (pa) is also a curiosity-inducing attraction that is worthwhile a visit. Lastly, don’t miss Spiaggia Di Cefalù, a place of serene interest in the town.

When you’re done exploring for the day, you’ll return to Palermo and your accommodation.

As you explore more of Palermo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Splendid Hotel la Torre, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorantino Sobremesa, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Quattro mani, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a fulfilling meal, continue your evening at Bar Touring, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Palermo Football Store offers a welcoming atmosphere for easing into the nightlife. Similarly, Goccio - L’arte Del Miscelare provides an excellent environment for a relaxed and enjoyable evening.

Relax and recharge in preparation for another adventurous day in Sicily!

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Day 4

Day 4

  • Palermo
  • Catania
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Drive 332 km, 5 hours 14 min

  • Chiesa Madonna della Rocca
  • Porta Catania
  • Basilica of St. Nicholas of Bari
  • Ancient theatre of Taormina
  • Villa Comunale di Taormina
  • Isola Bella
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On day 4 of your road trip in Sicily, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Taormina and Mazzarò. In the evening, you’ll end up in Catania, where you will stay for 2 nights.

Start your day at Chiesa Madonna Della Rocca. This history-steeped church is an increasingly popular place to see in Palermo. Then, wander over to Porta Catania. If symbolic sites excite you, this monument will be right up your alley. Nearby, you’ll also find Basilica Of St. Nicholas Of Bari. This history-steeped church is a favorite among visitors.

Palermo offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Ancient Theatre Of Taormina is a popular spot in the town that will captivate you with its unique charm. When you’re done at the archeological site, don’t forget to check out the detailed Villa Comunale Di Taormina. Take a moment to appreciate the fascinating details of this worthwhile park. Wrap up your self-guided tour of Palermo's top attractions with a visit to Isola Bella.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Catania. Catania offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Catania, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Ristorante da Antonio, a top-rated dining spot in Catania. If you're in the mood for something new, try Lido Arcobaleno, another premier location with a delectable menu. You might also want to book a table at Lido Azzurro. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Catania.

Continue your lively evening at Caffè Europa, a perfect place for winding down or revving up the night, depending on which mood you’re in. Insigne Cafè is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bohéme Mixology Bar ensures a night out tailored to your taste.

Savor another day of unforgettable experiences in Sicily!

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Day 5

Day 5

  • Catania
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Drive 138 km, 2 hours 12 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Temple of Apollo
  • Fountain of Diana
  • Island of Ortigia
  • Cathedral of Syracuse
  • More

On day 5 of your road trip in Sicily, you’ll start and end your day in Catania, but spend the day exploring what’s beyond the city. Since you will return to Catania for 1 night more, there’s no need to rush. Experience Syracuse to the fullest today with this curated day itinerary!

Today, you'll explore some of the most beautiful places in Catania, including a cave, an archeological site, a monument, a historical landmark, a church and much more! Start your day with a visit to Ear Of Dionysius. This up-and-coming cave is a must-visit in the city. When you’re ready for your next discovery, continue to Neapolis Archaeological Park, which may be one of the most breathtaking places you will experience today.

One of the best things about exploring Catania on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Temple Of Apollo, a captivating archeological site in the city. If you’re up for more discoveries, don’t forget to reserve some time for Diana Fountain and Ortygia. End your day with a visit to Cathedral Of Syracuse, a beloved church that’s sure to leave a lasting impression.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Catania.

Indulge in a memorable dining experience at one of Catania's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Il Gambero Pazzo, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Deliziosa offers an enticing alternative with its varied menu. Additionally, Lettera 82 Risto Pub is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Catania.

If you’re not ready to end the night just yet, Circus Cocktail Bar offers a perfect venue to relax and savor a drink. Similarly, Caffè Opera is well-suited for those looking to unwind in a social setting. Chiosco Sicilia Seltz is another excellent spot to enjoy a nightcap after a delightful meal.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Sicily.

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Day 6

Day 6

  • Catania
  • Palermo
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Drive 293 km, 4 hours 21 min

  • Tempio Di Zeus Olympios
  • Temple of Heracles
  • Valle dei Templi
  • Museo archeologico regionale Pietro Griffo
  • More

Experience an unparalleled adventure on day 6 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Agrigento. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Palermo. You will spend 1 night here for some well-deserved relaxation.

Discover a day packed with family-friendly attractions, breathtaking views, and photo-friendly spots in Catania. Begin your sightseeing with Temple Of Olympian Zeus. This locally appreciated point of interest is one of the top attractions in the city. Proceed to Temple Of Heracles, another must-visit attraction.

As you wander through the inviting streets of Catania, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Valle Dei Templi. This notable archeological site is a traveler-favorite. Not far away, you’ll find Archaeological Museum "pietro Griffo" Of Agrigento, another key site on your sightseeing itinerary.

When you’re done exploring for the day, you’ll drive to your hotel in Palermo. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Trattoria Ai Cascinari, a highly-rated dining destination in Palermo. If you're eager to try something different, consider Villa Boscogrande - Chef Natale Di Maria, another top spot with a tantalizing menu. You might also want to secure a reservation at MadoniEAT. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Palermo this evening.

Round off your dining experience by visiting Pasticceria Massaro, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bar Sanremo - Palermo, a bar catering to every mood and preference. Bar Touring likewise offers a unique atmosphere, perfect for a memorable night out.

Say good night to Palermo and look forward to another great day of your road trip in Sicily!

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Day 7

Day 7

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
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Day 7 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Catacombe Dei Cappuccini. This notable cemetery is a popular place to see in the city.

Maximize your last day in Sicily and go on a shopping spree in Palermo’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Sicily.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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