7-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Catania

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Photo of Palermo, Sicily, Italy. Seafront view.
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Escape the ordinary with this exciting 7-day road trip through Sicily. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 4 nights in Palermo and 2 nights in Catania. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Cefalù, Taormina, Catania, Syracuse, and Agrigento, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Welcome to Palermo, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 3 nights discovering what to see in Palermo before embarking on the next leg of your journey.

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Cotto e Bollito, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Bebop is another top choice with a popular menu. You could also check for a table at Eremiti Restaurant. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Palermo tonight.

Cap off your dinner by heading to Malox Cult, ideal for a leisurely evening with a drink in hand. Ai Giudici is another bar that offers an enjoyable setting. Similarly, Bar Italico is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise a toast to the start of your 7-day road trip in Sicily!

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Day2

Day 2

  • Palermo
  • More

Drive 31 km, 1 hour 38 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Santuario di Santa Rosalia, Palermo
  • More

Day 2 offers an itinerary packed with the best things to see in Palermo. You’ll stay in Palermo for 2 nights more, offering you enough time to explore at a relaxed pace.

Norman Palace is an ideal stop early in the day. This popular palace is a must-visit in the city. When you’re ready for your next discovery, continue to Palermo Cathedral, which may be one of the most historic places you will experience today.

One of the best things about exploring Palermo on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Quattro Canti, a captivating public square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Fontana Pretoria and Orto Botanico Di Palermo. End your day with a visit to Santuario Di Santa Rosalia, Palermo, an up-and-coming church that’s sure to leave a lasting impression.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at Osteria Mercede, a top-rated dining spot in Palermo. If you're in the mood for something new, try Trattoria Del Massimo, another premier location with a delectable menu. You might also want to book a table at Grand Hotel Piazza Borsa. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Palermo.

After savoring a delicious meal, step into the vibrant nightlife at Spina Bar Palermo, where the evening is just getting started. In the same way, Torrefazione Castagnetta Massimiliano (gelateria) offers a unique charm perfect for experiencing the local bar scene in Palermo. Monkey Pub is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and recharge in preparation for another adventurous day in Sicily!

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Day3

Day 3

  • Palermo
  • Cefalù
  • More

Drive 145 km, 2 hours 34 min

  • Castello di Cefalù
  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Porta della Pescara (Porta Marina)
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Cefalù Beach
  • More

On day 3 of your road trip, you’ll start and end your day in Palermo, where you have 1 night left to stay.

Embrace the thrill of the open road as you wave goodbye to Palermo and set your GPS to Cefalù. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour. Upon reaching Cefalù, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Castello Di Cefalù is an often recommended castle we recommend visiting today. Discover its visually striking features before continuing your self-guided tour to Rocca Di Cefalù, a history-steeped castle that’s well-regarded in the area.

Next, stop by Cefalù Cathedral, an inviting church. While you’re nearby, don’t forget to visit Porta Pescara (porta Marina), a visually striking and truly unique historical landmark. End your sightseeing at Lavatoio Medievale Fiume Cefalino - Cefalù (pa), a beloved historical landmark that’s highly recommended by travelers passing through the town.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Palermo.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Splendid Hotel la Torre, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorantino Sobremesa, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Quattro mani, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Bar Touring, a perfect place for winding down or revving up the night, depending on which mood you’re in. Palermo Football Store is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Goccio - L’arte Del Miscelare ensures a night out tailored to your taste.

Head back to your accommodation in Palermo and get some rest to prepare for another magical day of your road trip in Sicily.

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Day4

Day 4

  • Palermo
  • Taormina
  • Catania
  • More

Drive 332 km, 5 hours 14 min

  • Chiesa Madonna della Rocca
  • Porta Catania
  • Basilica of St. Nicholas of Bari
  • Ancient theatre of Taormina
  • Villa Comunale di Taormina
  • Isola Bella
  • More

On day 4 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 2 destinations, including Taormina and Mazzarò. When you’re not sightseeing, take time to relax at your chosen hotel in Catania, where you’ll be staying for 2 nights.

When you’re ready to jump back into the car and say goodbye to Palermo, you’ll hit the road in the direction of Taormina. This drive usually takes around 3 hours 14 min.

One of our top recommendations for your sightseeing is Chiesa Madonna Della Rocca. Spend some time admiring the inviting features of the church before you continue to your next stop. Then, head to Porta Catania. This increasingly popular monument is a traveler-favorite in the town.

If you're keen to see more, continue to Basilica Of St. Nicholas Of Bari. Feed your curiosity by learning something new about the church. Next, take your journey to Villa Comunale Di Taormina, a worthwhile park.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Catania may take around 51 min. Upon your arrival in Catania, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Our first attraction recommendation in Mazzarò is Ancient Theatre Of Taormina, a popular archeological site that draws attention for its enchanting features.

When you’re done exploring for the day, you’ll drive to your hotel in Catania. Check in and relax before you head out to tour the city.

Catania is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Catania.

Savor the flavors at Ristorante da Antonio, a top pick for dinner tonight. Alternatively, Lido Arcobaleno beckons with its unique menu offerings. Also, consider Lido Azzurro. With its consistent customer satisfaction, it’s an excellent option for dining in Catania tonight.

Extend your evening after a delightful meal by visiting Caffè Europa, which offers the perfect atmosphere for a night out. Moreover, Insigne Cafè is another popular option for a drink or two. Likewise, Bohéme Mixology Bar also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day5

Day 5

  • Catania
  • Syracuse
  • More

Drive 138 km, 2 hours 12 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Temple of Apollo
  • Fountain of Diana
  • Island of Ortigia
  • Cathedral of Syracuse
  • More

Greet day 5 of your road trip in Sicily with a smile and start your day with a hearty breakfast. You have 1 night to stay in Catania, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Syracuse.

When you’ve had your share of Catania, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Syracuse. Your travel time is around 50 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Ear Of Dionysius, a curiosity-inducing cave that everyone visiting Syracuse should see. Next, head to Neapolis Archaeological Park. This breathtaking archeological site is one of the most well-known attractions in the region.

If you're keen to see more, don’t miss out on Temple Of Apollo, a picture-perfect archeological site popular among locals as well as travelers. Diana Fountain is an excellent attraction to visit next. Spend some time learning more about this frequently visited monument before you continue your journey. Lastly, visit Ortygia, a respected historical landmark and a top attraction in the city.

When you’re done exploring for the day, you’ll return to Catania and your accommodation.

Catania is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Catania.

Treat yourself to a wonderful meal at Il Gambero Pazzo, a top-rated dining spot in Catania. If you're in the mood for something new, try Deliziosa, another premier location with a delectable menu. You might also want to book a table at Lettera 82 Risto Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Catania.

Let the evening flow smoothly from dinner to drinks at Circus Cocktail Bar, a top-rated bar in the area. For other recommendations, Caffè Opera provides a perfect setting for rounding out your night with style and great drinks. Likewise, Chiosco Sicilia Seltz offers a memorable night with diverse drink options and excellent service.

Say good night to Catania and look forward to another great day of your road trip in Sicily!

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Day6

Day 6

  • Catania
  • Agrigento
  • Palermo
  • More

Drive 293 km, 4 hours 21 min

  • Tempio Di Zeus Olympios
  • Temple of Heracles
  • Valle dei Templi
  • Museo archeologico regionale Pietro Griffo
  • More

Dive into day 6 of your remarkable road trip in Sicily. Today you'll explore 1 destination, including Agrigento. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo, where you'll spend 1 night.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Agrigento.

Embrace the thrill of the open road as you wave goodbye to Catania and set your GPS to Agrigento. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 56 min. Upon reaching Agrigento, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Spend some time soaking in the atmosphere before continuing to Temple Of Heracles, a culturally significant archeological site that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Valle Dei Templi, an interesting archeological site that offers a unique experience. Be sure to also explore Archaeological Museum "pietro Griffo" Of Agrigento, a nearby museum, highly recommended by other travelers.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Trattoria Ai Cascinari, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Villa Boscogrande - Chef Natale Di Maria, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of MadoniEAT, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a fulfilling meal, continue your evening at Pasticceria Massaro, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bar Sanremo - Palermo offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Touring provides an excellent environment for a relaxed and enjoyable evening.

Get a good night's sleep and look forward to another great day on the road in Sicily!

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Day7

Day 7

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
  • More

Day 7 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Catacombe Dei Cappuccini. This interesting cemetery is a hotspot among locals.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

If you're in the mood to try something new, consider RISTORANTE PRIMI PIATTI, another top spot with a mouthwatering menu.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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