7-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence

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Photo of Sand beach in Camogli by Genoa, Italy.
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Explore the best of Italy on a remarkable 7-day road trip! Combine exploration with relaxation on a self-drive tour featuring Genoa, Manarola, Corniglia, Vernazza, Pisa, Florence, Siena, and Lucca.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 4 nights in Genoa and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Genoa, Manarola, Corniglia, Vernazza, Pisa, Florence, Siena, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Genoa - Arrival day
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  • porto antico
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Your road trip adventure in Italy begins as soon as you reach Genoa and pick up your car. You’ll stay here for 3 nights and explore what to see in Genoa, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Porto Antico. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Genoa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at 7 Sensi cucina decontaminata, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Alla Lunga Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Grand Hotel Savoia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Scurreria Beer & Bagel, a well-loved spot among locals and tourists. Or, head to La Lepre. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Pisacane Iii, another top-rated place in the area.

Raise a toast to the start of your 7-day road trip in Italy!

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Day2

Day 2

  • Genoa
  • More

Drive 11 km, 48 min

  • Lighthouse of Genoa
  • Galata - Museo del mare
  • Aquarium of Genoa
  • Genoa Cathedral
  • Doge's Palace
  • piazza De Ferrari
  • More

Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Genoa.

Genoa is brimming with adventures.

One of the most frequently visited attractions included on the itinerary is Lighthouse Of Genoa. This picture-perfect lighthouse will help you start your sightseeing on top. Then, take a leisurely stroll to Galata Museo Del Mare (complex) and learn what makes this standout maritime museum unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the extraordinary Aquarium Of Genoa. After exploring the aquarium, head to Genoa Cathedral. This increasingly popular church is a highlight in Genoa. Lastly, don’t forget to check out the well-known Piazza De Ferrari. Enjoy exploring this incredible public square at your own pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Enjoy a delicious meal at Zeffirino, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Vegia Zena, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria delle Grazie. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Head back to your accommodation in Genoa and get some rest to prepare for another magical day of your road trip in Italy.

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Day3

Day 3

  • Genoa
  • More

Drive 249 km, 4 hours 46 min

  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Ruins of Doria Tower
  • Church of St. Margaret of Antioch
  • Scalinata Lardarina
  • More

On day 3 of your road trip, you'll get the chance to experience Manarola, Corniglia, and Vernazza. At the end of the day, you'll drive back to Genoa, where you still have 1 night left to stay.

Check out the beloved observation deck, Manarola Overlook Viewpoint. Afterward, continue to Cinque Terre National Park, a national park every traveler should visit. As you explore Genoa’s charming streets, take in the lively atmosphere and get to know the character of the village.

Next, make your way to Ruins Of Doria Tower. This locally appreciated monument is an essential stop. Following that, head to Church Of St. Margaret Of Antioch, another must-visit site that will enhance your experience. Don’t forget to stop by Scalinata Lardarina, an underrated hiking area in the village.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Osteria Sant'Ilario, an iconic dining spot in Genoa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Cialtroneria, a popular restaurant in Genoa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Manhattan Bar, a hidden gem nestled in Genoa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day4

Day 4

  • Genoa
  • Florence
  • More

Drive 271 km, 3 hours 58 min

  • “Tuttomondo” (Keith Haring)
  • Santa Maria della Spina
  • Knights' Square
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • More

Your itinerary for day 4 of your road trip in Italy includes 1 stop and features some of the highlights of Pisa. At the end of the day, enjoy the comforts of a top-rated hotel in Florence, where you'll spend 2 nights.

Make time for “tuttomondo” (keith Haring), an often recommended art installation that is worthwhile a visit in the city. Nearby, you’ll find Santa Maria Della Spina, enchanting visitors with its visually striking appeal. Continue your exploration at Knights' Square. This public square is one of the city’s most curiosity-inducing spots.

Enjoy the freedom of exploring Genoa at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Leaning Tower Of Pisa. After exploring the monument, head to the globally renowned Piazza Del Duomo, Pisa. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Pisa Cathedral, a place of breathtaking interest in Genoa.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Manifattura, where the evening is just getting started. In the same way, Se·sto On Arno Rooftop Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Il Vinile is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day5

Day 5

  • Florence
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Drive 8 km, 1 hour 2 min

  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • piazzale Michelangelo
  • More

On day 5 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

Visiting Cathedral Of Santa Maria Del Fiore is always a good idea. This famous church is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the remarkable wonders of Piazza Della Signoria, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Ponte Vecchio. This timeless historical landmark offers an enriching experience. For a change of pace, head to Uffizi Gallery, where you can take in historic features. Conclude your self-guided sightseeing tour with a visit to Basilica Of Santa Croce In Florence and Piazzale Michelangelo These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Ditta Artigianale, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Da Burde is another top choice with a popular menu. You could also check for a table at Casa Toscana. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

Continue the enjoyment post-dinner at Bar 50 Rosso, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bitter Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Archea Brewery. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day6

Day 6

  • Florence
  • Genoa
  • More

Drive 380 km, 4 hours 59 min

  • Siena Cathedral
  • piazza del Campo
  • Walls of Lucca
  • Porta San Pietro
  • More

Dive into day 6 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Siena and Lucca. At the end of the day, you’ll unwind at one of the finest accommodations in Genoa, where you'll spend 1 night.

Siena Cathedral is must-visit church and a great option for a daytime tour of the area. Continue your journey to Piazza Del Campo, a widely recognized public square, located just a leisurely stroll away. Next, head to Mura Di Lucca, a culturally significant historical landmark, also available for your discovery today.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Vivarelli, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Trattoria Ugo, another top spot with a mouthwatering menu. You might also want to secure a reservation at TAZZE PAZZE Specialty Coffee. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day7

Day 7

  • Genoa - Departure day
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  • Via Garibaldi
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Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Via Garibaldi. This intriguing street is a hotspot among locals.

Take some time to indulge in shopping at Genoa’s popular marketplace, Via Garibaldi. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

If you're in the mood for something new, try Il Marin, another premier location with a delectable menu.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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