7-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome and Florence

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View of the Pescara city hall and surrounding buildings, Pescara, Italy.
A visit in the biggest city of Abruzzo region, in the Adriatic sea.
The historic center of the sea city in Abruzzo region, during a summer sunday morning.
The Ponte del Mare monumental bridge and the Ferris wheel at the dusk, in the canal and port of Pescara city, Abruzzo region
Photo of Tourist port "Marina di Pescara".
Church Of The Sacred Heart of Jesus in Pescara city, Abruzzo region, Italy.
The view in the dusk from Ponte del Mare monumental bridge in the canal and port of Pescara city, Abruzzo region.
Photo of "Callalily" mural by Italian artist Pep Marchegiani on a motorway pylon.
Photo of  "La nave" (the boat) by italian sculptor Pietro Cascella.
Photo of Ponte del Mare (Sea Bridge) and boats anchored in the harbor in the channel of the Pescara River and the Majella mountain in the background
View of the Pescara seafront, with the bell tower of the Divino Amore church and the Gran Sasso
view of the city of Pescara in Italy, with the Adriatic Sea in the background
Facade of the building of the Province of Pescara in Abruzzo
Pescara
Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
Photo of Fountain di Trevi in Rome, Italy.
Bridge Il Tevere a Ponte Vittorio Emanuele II in Rome, Italy.
Hadrian Mausoleum, Rome, Italy.
 Vatican dome of San Pietro and Sant Angelo Bridge, over Tiber river in Rome, Italy.
panoramic view of Rome and St. Peter's Basilica, Italy.
View of Pantheon in the morning, Rome, Italy.
Rome, Italy. Stunning twilight view of Forum ancient ruins, seen from Capitoline hill with Colosseum in background.
Aerial view of forum romanum and surrounding areas of historical centre of italian capital rome.
Cozy old street in Trastevere in Rome, Italy. Trastevere is rione of Rome, on the west bank of the Tiber in Rome, Lazio, Italy. Architecture and landmark of Rome.
Aerial panorama of St. Peter's Square in Vatican with Rome in the background. Italy.
photo of view of Illuminated Fontana Di Trevi, Trevi Fountain at Dusk, Rome, Italy.
photo of view of Spanish Step, Rome, Italy.
photo of view of Museum Luasanne, Rome, Italy.
photo of view Roma Wall of Lugo, Rome, Italy.
photo of view of Roman Bridge Cordoba, Rome, Italy.
photo of view of Roman ruins in Rome, Forum, Rome, Italy.
photo of view of Roman Bridge of Cordoba, Rome, Italy.
photo of view of The Iconic, the legendary Coliseum of Rome, Italy.
photo of view of Rome, Italy: The Roman Forum, Latin: Forum Romanum, Italian: Foro Romano, Rome, Italy.
photo of view of Trevi Fountain (Fontana di Trevi) in Rome, Italy. Trevi is most famous fountain of Rome. Architecture and landmark of Rome, Postcard of Rome, Italy.
Aerial view of the Cattedrale di Santa Maria del Fiore in Florence, Italy, overlooking the city
Photo of Florence Aerial View of Ponte Vecchio Bridge during Beautiful Sunny Day, Italy.
Photo of Woman enjoys beautiful view on famous Duomo cathedral in Florence, standing on empty cathedral square during morning time.
Photo of Summer street cafe on Piazza della Repubblica in Florence, Toscana province, Italy.
Photo of Giotto's Campanile - An aerial dusk view of Giotto's Campanile and the historical Old Town of Florence, as seen from the top of Brunelleschi's Dome of the Florence Cathedral. Florence, Tuscany, Italy.
Photo of Ponte Vecchio, old bridge over Arno River, Florence, Tuscany, Italy.
Photo of The Colossus of the Apennines, majestic stone sculpture by Giambologna located in the park of Villa Demidoff in Florence, Italy.
Photo of Fountain of Neptune in Florence in early morning.
Photo of Sunset view of Florence, Ponte Vecchio, Palazzo Vecchio and Florence Duomo, Italy. Architecture and landmark of Florence. Cityscape of Florence.
Vintage carousel and tourists in Piazza della Repubblica (Republic Square) and the arch in honor of the first king of united Italy on background in Florence, Italy.
Photo of Arches of the Vasari Corridor (Corridoio Vasariano) in Florence, Tuscany, Italy. View of the Lungarno degli Archibusieri.
cheerful senior woman cycling with her electric mountain bike above downtown of Florence with stunning view over the old city, Tuscany, Italy
Facade of Palazzo Pitti palace with Gallery of Modern Art large building on Piazza dei Pitti square in historical centre of Florence city, blue sky white clouds, Tuscany, Italy
photo of view of Florence,Italy.
photo of view of Florence,Italy.
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Explore the best of Italy on a 7-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Pescara, Rome, Florence, Pisa, and Santa Maria degli Angeli. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Pescara, Rome, Florence, Pisa, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Nature Reserve Pineta Dannunziana
ColosseumRoman ForumPantheonSpanish StepsPiazza di SpagnaTrevi Fountain
St Peter's BasilicaSistine ChapelVatican MuseumsPiazza NavonaTrastevereMonti
Basilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioPiazza della RepubblicaCathedral of Santa Maria del Fiorepiazza della Signoria
Piazza del Duomo, PisaPisa CathedralLeaning Tower of PisaAngelo CadutoCentral Marketpiazzale Michelangelo
Basilica of San Francesco d'AssisiPortico of Monte FrumentarioChurch of Santa Maria sopra Minerva in AssisiPiazza del ComuneRocca Maggiore
Parrocchia Spirito Santo

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Day 1

Day 1

  • Pescara - Arrival day
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  • Nature Reserve Pineta Dannunziana
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Welcome to Pescara, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Pescara's charm before embarking on the next leg of your journey.

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Nature Reserve Pineta Dannunziana, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Pescara. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Dine in style at Taverna 58, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Carlo Ferraioli boasts a menu that's sure to impress. Also, be sure to check out Sesamo Nero. Known as a local hotspot, it’s a great choice for tonight in Pescara.

If you’re not ready to end the night just yet, Posa Caffè Pescara offers a perfect venue to relax and savor a drink. Similarly, Bar Mixer is well-suited for those looking to unwind in a social setting. Temple Bar Irish Pub is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 7-day road trip in Italy!

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Day 2

Day 2

  • Pescara
  • Rome
  • More

Drive 214 km, 3 hours 27 min

  • Colosseum
  • Roman Forum
  • Pantheon
  • Spanish Steps
  • Piazza di Spagna
  • Trevi Fountain
  • More

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 2 nights here for some well-deserved relaxation.

Set out on a day brimming with fun adventures, scenic views, and photo-friendly spots. Start at the globally renowned Colosseum, a picture-perfect archeological site in Pescara. Next, go to Roman Forum.

After visiting Colosseum and Roman Forum, have a stroll along Pescara's streets and take in the local charm. Continue your sightseeing by heading to Pantheon. This instagrammable monument offers a unique experience. Spanish Steps is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazza Di Spagna, one of the most romantic places to visit in Pescara. If you still have some time left for sightseeing, we also recommend stopping by Trevi Fountain.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at La Bottega Roma, a highly-rated dining destination in Rome. If you're eager to try something different, consider Pasta In Corso, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Continue your lively evening at La Botticella Of Poggi Giovanni, a perfect place for winding down or revving up the night, depending on which mood you’re in. Almalu Trastevere is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Viminale Di Pepi Maurilio ensures a night out tailored to your taste.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Rome
  • More

Drive 9 km, 59 min

  • St Peter's Basilica
  • Sistine Chapel
  • Vatican Museums
  • Piazza Navona
  • Trastevere
  • Monti
  • More

On day 3 of your road trip, you’ll start and end your day in Rome, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Vatican City and Rome. You still have 1 night left in Rome.

A top thing to do today is to explore Trastevere, a must-see neighborhood in Vatican City. It's the perfect starting point for touring the top attractions in the area. You can also visit Monti, an ideal neighborhood for continued sightseeing.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring fun adventures, romantic experiences, and breathtaking views. Start at St. Peter's Basilica, an iconic major basilica in the city.

After exploring the art museum, visit the wondrous Piazza Navona.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Sant' Eustachio Caffè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Yellowsquare Rome is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffè Portofino ensures a night out tailored to your taste.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 4

Day 4

  • Rome
  • Florence
  • More

Drive 276 km, 3 hours 31 min

  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • More

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most interesting attractions included on the itinerary is Basilica Of Santa Croce In Florence. This monumental church will help you start your sightseeing on top. Then, take a leisurely stroll to Uffizi Gallery and learn what makes this respected art gallery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the timeless Ponte Vecchio. After exploring the historical landmark, head to Piazza Della Repubblica. This interesting public square is a highlight in Rome. As your day continues, stop by Cathedral Of Santa Maria Del Fiore, known for its history-steeped features. Lastly, don’t forget to check out the spectacular Piazza Della Signoria. Enjoy exploring this incredible public square at your own pace.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 5

Day 5

  • Florence
  • More

Drive 183 km, 3 hours 8 min

  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Leaning Tower of Pisa
  • Angelo Caduto
  • Central Market
  • piazzale Michelangelo
  • More

On day 5 of your road trip, you’ll start and end your day in Florence, where you'll stay for 1 night more.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, scenic views, and picturesque spots. Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Piazza Del Duomo, Pisa is the first of them. Spend some time admiring this UNESCO world heritage-designated public square before continuing your journey. Pisa Cathedral is your next stop. This often recommended church is one of the best-rated sights in Florence.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Leaning Tower Of Pisa. This breathtaking monument is a sight to behold. To round off your sightseeing experience, visit Angelo Caduto and Central Market. If time allows, end your day with Piazzale Michelangelo, a symbolic observation deck that offers a memorable conclusion to your exploration.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Round off your dining experience by visiting Bar 50 Rosso, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bitter Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 6

Day 6

  • Florence
  • Pescara
  • More

Drive 403 km, 5 hours 26 min

  • Basilica of San Francesco d'Assisi
  • Portico of Monte Frumentario
  • Church of Santa Maria sopra Minerva in Assisi
  • Piazza del Comune
  • Rocca Maggiore
  • More

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Santa Maria degli Angeli, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Pescara. You’ll stay here for 1 night.

Florence is brimming with adventures. Today’s wonderful stops include a church, a historical landmark, a public square, a castle and much more! Begin your sightseeing adventure at the well-known Basilica Of San Francesco D'assisi and allow yourself time to explore. Just a short distance away you'll find your next stop, Portico Of Monte Frumentario, a picture-perfect historical landmark that draws visitors from far and near.

Continue your journey to Church Of Santa Maria Sopra Minerva In Assisi, one of the town’s most intriguing spots that you shouldn’t miss. Another great site to visit is the frequently visited Piazza Del Comune. When you're finished at the public square, Rocca Maggiore awaits your visit. This castle is a history-steeped highlight on today's itinerary.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pescara. Pescara offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Pescara. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Ciacco, an excellent option for tonight's dining. Looking for something different? Bar Sara offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante Franco. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Pescara.

Continue your evening by exploring the vibrant nightlife scene at Bar Napoli, a prime destination for a thrilling night out. Also, don’t forget to check out Bar Supermarket, a bar that offers unique local touches. Likewise, Post Bar provides an excellent alternative for a fun evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 7

Day 7

  • Pescara - Departure day
  • More
  • Parrocchia Spirito Santo
  • More

Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Parrocchia Spirito Santo, an instagrammable church before you head out.

As your final day in Italy unfolds, enjoy a last-minute shopping spree in Pescara's best shopping area, Centro Commerciale Pescara Porta Nuova. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

If you're in the mood to try something new, consider La Taverna Antica, another top spot with a mouthwatering menu.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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