7-Day Italy Road Trip from Pisa to Milan, Florence, and Rome and surrounding area

Dive into day 2 of your remarkable road trip in Italy. Today you will explore Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Milan. You’ll stay here for 1 night.

A top pick for your self-guided sightseeing tour today is Knights' Square. Previous visitors have rated this square an average of 4.5 out of 5 stars in 9,051 reviews.

Leaning Tower Of Pisa is a local recommendation that you also can pay a visit today. This bell tower is rated an average of 4.7 out of 5 stars in 116,882 reviews. The attraction welcomes 3,200,000 visitors every year.

Another attraction you won't want to miss is Pisa Cathedral. This cathedral is rated an average of 4.8 out of 5 stars in 8,361 reviews.

Piazza Del Duomo, Pisa is another outstanding experience in Pisa. Around 104,550 travelers have rated this square an average of 4.7 out of 5 stars.

If you long for more, Campo Santo is not far away. This cemetery is a lovely addition to your itinerary. Previous visitors have rated it an average of 4.6 out of 5 stars in 586 reviews. The attraction gets an estimated 3,200,000 visitors every year.

When you’re done exploring for the day, you’ll drive to Milan, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Milan, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Start your culinary exploration in Milan by securing a reservation at Enrico Bartolini al Mudec. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of creative cuisine. For another dining delight, visit Seta by Antonio Guida, celebrated for its delectable international, and contemporary menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Il Luogo Aimo e Nadia, a top local spot known for its tantalizing italian contemporary, and modern menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Explore the vibrant nightlife at Nottingham Forest after your meal, a hub for lively evenings and memorable moments. Or, head to Armani/bamboo Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Mag Cafe is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Milan. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 1 night.

Seize the day by visiting some of the best attractions in the area, like Duomo Di Milano Museum. This extraordinary art museum has an average rating of 4.8 out of 5 stars from 138,554 visitors. Each year, around 341,609 people visit this remarkable site to admire its features and learn more about it.

Next, make your way to Galleria Vittorio Emanuele Ii. This commercial gallery is rated an average of 4.7 out of 5 stars in 91,394 reviews.

While in Milan, we also recommend a visit to Sforzesco Castle Art Library. This library has been rated an average of 4.6 out of 5 stars in 68,714 reviews.

If you’re keen to explore even more, then consider a visit to Parco Sempione. With an average rating of 4.6 out of 5 stars by 72,914 travelers, this park is a highly recommended stop on your sightseeing around Milan.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy an outstanding dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an exceptional italian contemporary menu. If you are in the mood for trying an alternative dining experience, consider visiting the nearby 2-star Michelin-awardee, Santa Elisabetta, known for its delicious creative, and mediterranean cuisine. Another highly-recommended restaurant in Florence is Gucci Osteria da Massimo Bottura, a renowned restaurant with a 1-star Guide Michelin recognition, known for its delicious italian contemporary, and international menu.

Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Archea Brewery. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Relax and recharge in preparation for another adventurous day in Italy!

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Florence, and Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 2 nights here for some well-deserved relaxation.

When you’re ready for some sightseeing, make your way to Cathedral Of Santa Maria Del Fiore. This much-appreciated church is rated 4.8 out of 5 stars in 76,359 reviews.

Next up is Ponte Vecchio. This deck arch bridge has an average rating of 4.7 out of 5 stars from 118,099 visitors.

Another top sightseeing recommendation is Piazzale Michelangelo. This square has been rated 4.8 out of 5 stars in 77,744 reviews.

Continue your road trip and head to your next destination, Vatican City, Vatican City. This car ride takes around 3 hours 9 min.

An excellent attraction to start your day with is St. Peter's Basilica. This major basilica typically receives around 11,000,000 visitors every year and is rated an average of 4.8 out of 5 stars in 131,043 reviews.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean, and contemporary cuisine. For another culinary dining option, venture to Il Pagliaccio, celebrated for its delectable creative, and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean, and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Sant' Eustachio Caffè offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Day 5 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

When you’re ready for some sightseeing, make your way to Colosseum. This much-appreciated roman amphitheatre is rated 4.7 out of 5 stars in 328,821 reviews. Each year, 7,400,000 people visit this site to admire its unique features.

Next up is Roman Forum. This square has an average rating of 4.7 out of 5 stars from 114,450 visitors.

Another top sightseeing recommendation is Pantheon. This roman temple has been rated 4.8 out of 5 stars in 189,682 reviews. Every year, 30,000,000 travelers include this attraction on their travel itinerary.

Piazza Navona is another attraction you have the opportunity to visit today. This square has an average rating of 4.7 out of 5 stars from 158,771 reviews.

To continue your sightseeing, head over to Castel Sant'angelo. This museum is rated an average of 4.7 out of 5 stars in 72,431 reviews. Approximately 918,591 people come to see this attraction every year.

If you have an appetite for more adventure, check out the fantastic selection of tours and tickets offered in Rome on this day of your trip. You'll find the most recommended ones below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to book a table at DEROMA - Farine Romane, a popular restaurant in Rome. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Rome at La Taverna Italiana, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Centro. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Rome tonight.

Explore the vibrant nightlife at The Apartment Bar Roma after your meal, a hub for lively evenings and memorable moments. Or, head to Hotel Hassler Roma for a great selection of flavorful drinks and a charming setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.