7-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling south to Florence and Rome

On day 2 of your road trip, you will have an entire day to discover what to see in Venice. You’ll stay in Venice for 1 night.

Whether you decide to explore Venice on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Gallerie Dell'accademia is must-visit art gallery and a great option for a daytime tour of the area. Continue your journey to St Mark's Basilica, a popular church, located just a leisurely stroll away. Next, head to Piazza San Marco, an enchanting public square, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Venice. When you're ready, let your sightseeing route take you to the popular Doge's Palace. If you’re looking for more, Bridge Of Sighs is also a popular attraction that is worthwhile a visit. Lastly, don’t miss Venetian Arsenal, a place of picture-perfect interest in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Dine in style at Generator Venice, a top recommendation for dinner tonight. Or, for a change of pace, Nevodi boasts a menu that's sure to impress. Also, be sure to check out Ristorante La Piazza. Known as a local hotspot, it’s a great choice for tonight in Venice.

Unwind after your meal by stepping into Il Mercante. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, The Irish Pub Venezia offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Ai Stagneri, another top-rated bar in the area.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Florence’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Venice behind. This drive usually takes around 2 hours 56 min. Florence welcomes you with a multitude of unique vacation experiences.

One of our top recommendations for your sightseeing is Bargello National Museum. Spend some time admiring the photogenic features of the museum before you continue to your next stop. Then, head to Basilica Of Santa Croce In Florence. This notable church is a traveler-favorite in the city.

If you're keen to see more, continue to Uffizi Gallery. Feed your curiosity by learning something new about the art gallery. Next, take your journey to Ponte Vecchio, a timeless historical landmark. Conclude your sightseeing at Piazza Della Signoria, known for its symbolic features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Ristorante Oliviero 1962, a top recommendation for dinner tonight. Or, for a change of pace, Di Poneta Novoli boasts a menu that's sure to impress. Also, be sure to check out Caffe San Firenze. Known as a local hotspot, it’s a great choice for tonight in Florence.

Extend your evening after a delightful meal by visiting Manifattura, which offers the perfect atmosphere for a night out. Moreover, Se·sto On Arno Rooftop Bar is another popular option for a drink or two. Likewise, Il Vinile also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Say good night to Florence and look forward to another great day of your road trip in Italy!

Greet day 4 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Florence, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Florence, Siena, and Pisa.

Let Cathedral Of Santa Maria Del Fiore set the tone for the day. Spend some time admiring this visually striking church before continuing your journey. Galleria Dell'accademia is your next stop. This popular art gallery is one of the best-rated sights in Florence.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Siena may take around 1 hour 15 min. Upon your arrival in Siena, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Set out on a self-guided sightseeing tour at Piazza Del Campo and explore the UNESCO world heritage-listed features.

Continue your road trip and head to your next destination, Pisa. This car ride takes around 1 hour 53 min.

One of our top recommendations for your sightseeing is Leaning Tower Of Pisa. Spend some time admiring the culturally significant features of the monument before you continue to your next stop.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Bar 50 Rosso, where the evening is just getting started. In the same way, Bitter Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Rome and Vatican City. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 1 night.

Fasten your seatbelt and make your way to your next stop — Rome, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Rome may take around 3 hours 7 min without traffic disruptions. Upon arrival in Rome, we highly recommend checking out some of the top attractions.

Pantheon is a world-famous monument we recommend visiting today. Discover its photogenic features before continuing your self-guided tour to Trevi Fountain, a romantic monument that’s well-regarded in the area.

Next, stop by Spanish Steps, a history-steeped public square.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, La Botticella Of Poggi Giovanni stands out as an excellent choice for a post-dinner cocktail. Alternatively, Almalu Trastevere offers an ideal atmosphere to enjoy the pleasures of the night. Bar Viminale Di Pepi Maurilio is also a great option that provides a perfect setting for a relaxing evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 6 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Bologna are on today's agenda. In the evening, you’ll end up in Venice, where you will stay for 1 night.

Continue your road trip and head to your next destination, Bologna. This car ride takes around 4 hours 7 min.

For a more meaningful self-guided tour of the city's best attractions, visit Fountain Of Neptune, Bologna, a beloved monument that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Bologna Cathedral and admire its grand features.

When you’re ready, continue to Piazza Maggiore, a famous public square beloved by locals and tourists alike. Don't miss out on Two Towers, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Piazza Santo Stefano, a visually striking place to see that you won’t regret spending some extra time discovering.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Don’t miss out on dining at Osteria Alla Staffa, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Bistrot de Venise, another top spot with a mouthwatering menu. You might also want to secure a reservation at Corte Sconta. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Continue the enjoyment post-dinner at Dolce Vita Venezia, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Tarnowska's American Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar All'angolo. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass to another unforgettable day in Italy!