One-Week Italy Self-Drive Road Trip With Itinerary from Brindisi traveling west to Alberobello, Matera, Naples, and Rome

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Explore the best of Italy on a 8-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Brindisi, Alberobello, Martina Franca, Conversano, Polignano a Mare, Matera, Pompei, Naples, Rome, and Orvieto. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 1 night in Alberobello, 1 night in Matera, 1 night in Naples, and 2 nights in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Brindisi, Alberobello, Martina Franca, Conversano, Polignano a Mare, Matera, Pompei, Naples, Rome, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Colonne Romane
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out End Of The Via Appia Antica, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Brindisi. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Bracerie Escosazio, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Penny offers an enticing alternative with its varied menu. Additionally, Piadineria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Brindisi.

Extend your evening after a delightful meal by visiting Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, which offers the perfect atmosphere for a night out. Moreover, Eden Cafè is another popular option for a drink or two. Likewise, Altair Cafè also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast to the start of your 8-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Alberobello
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Drive 176 km, 3 hours 34 min

  • Swabian Castle of Brindisi
  • Trulli di Alberobello Puglia
  • Basilica di San Martino
  • Torre Castiglione
  • Monumento a Domenico Modugno
  • Lungomare di Polignano a Mare
  • More

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 5 stops and experience some of the highlights of Brindisi, Alberobello, Martina Franca, Conversano, and Polignano a Mare. At the end of the day, you will enjoy the comforts of a top-rated hotel in Alberobello, which will be your home away from home for 1 night.

Get ready for a day filled with family-friendly attractions, breathtaking views, and photo-friendly spots in the charming city of Brindisi. Your adventure starts at Swabian Castle Of Brindisi, an increasingly popular local hot spot. Another notable attraction to explore is Trulli Di Alberobello Puglia. This captivating historical landmark is known for its culturally significant appeal.

After soaking in the highlights of these sights, take some time to wander Brindisi's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Basilica Di San Martino. This culturally significant church offers a fascinating experience that many visitors find memorable. Torre Castiglione is also worth visiting, along with Monumento A Domenico Modugno. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Lungomare Di Polignano A Mare. This worthwhile boardwalk provides a fitting finale to your sightseeing.

When you’re done exploring for the day, you’ll drive to your hotel in Alberobello. Check in and spend some time relaxing before you head out to tour the town.

As you explore more of Alberobello, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Ristorante "I Primi di Puglia" - Alberobello, an iconic dining spot in Alberobello. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Alberobello
  • Matera
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Drive 73 km, 1 hour 50 min

  • Casa Grotta del Casalnuovo
  • Casa Grotta nei Sassi di Matera
  • Church of Saint Mary of Idris
  • Sassi di Matera
  • Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
  • Palombaro lungo
  • More

On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Matera. In the evening, you’ll end up in Matera, where you will stay for 1 night.

A blend of family-friendly attractions, scenic views, and picturesque spots await you in Alberobello on today’s itinerary. First up is the often recommended cave, Casa Grotta Del Casalnuovo. Afterward, continue to Casa Grotta Nei Sassi Di Matera, a museum every traveler should visit.

As you explore Alberobello’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Church Of Saint Mary Of Idris. This up-and-coming church is an essential stop. Following that, head to Sassi Di Matera, another must-visit site that will enhance your experience. Don’t forget to stop by Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio, an increasingly popular church in the city. Finally, end your day with a visit to Palombaro Lungo, a photogenic cave system that offers the perfect conclusion to your sightseeing of the day.

At the end of the day, you will drive to Matera, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Matera. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 4

Day 4

  • Matera
  • Naples
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Drive 251 km, 3 hours 40 min

  • Archaeological Park of Pompeii
  • Basilica
  • Naples National Archaeological Museum
  • piazza del Plebiscito
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Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pompei and Naples. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 1 night here for some well-deserved relaxation.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Matera allows for both. Start by heading to Archaeological Park Of Pompeii. This notable archeological site provides an insightful glimpse into the town's identity. Next, discover Basilica, an UNESCO world heritage-listed archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Naples National Archaeological Museum, a popular museum. When you’re done, don’t forget to make a stop at the astonishing Piazza Del Plebiscito.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at L'Oca Nera Irish Pub, a top pick for dinner tonight. Alternatively, Mimì alla Ferrovia beckons with its unique menu offerings. Also, consider Spuzzulè Winebar. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

Extend your evening after a delightful meal by visiting Happening Cocktail Bar, which offers the perfect atmosphere for a night out. Moreover, Shanti Art Musik Bar is another popular option for a drink or two. Likewise, Gran Caffè Gambrinus also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Savor another day of unforgettable experiences in Italy!

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Day 5

Day 5

  • Naples
  • Rome
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Drive 232 km, 3 hours 26 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.

Prepare for a day full of family-friendly attractions, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Colosseum. This timeless archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Roman Forum, one of the city’s best highlights.

Next, check out Trevi Fountain, one of the most wondrous places to see in Naples. This monument is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Pantheon. Wander around and soak in the culturally significant atmosphere this monument offers. Then, head to Piazza Navona, a top-rated public square that adds another dimension to your day.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at La Bottega Roma, a top recommendation for dinner tonight. Or, for a change of pace, Pasta In Corso boasts a menu that's sure to impress. Also, be sure to check out Trattoria Vecchia Roma. Known as a local hotspot, it’s a great choice for tonight in Rome.

Keep the excitement of the evening going by visiting a bar or two. La Botticella Of Poggi Giovanni is an excellent place to start. You could also check out Almalu Trastevere, offering a different kind of charm. A last recommendation for the day is Bar Viminale Di Pepi Maurilio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 6

Day 6

  • Rome
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Drive 16 km, 1 hour 4 min

  • Vatican Museums
  • Sistine Chapel
  • St Peter's Basilica
  • Piazza di Spagna
  • Spanish Steps
  • Trastevere
  • More

At the end of the day, you'll drive back to Rome, where you'll stay for 1 night more.

Make sure to visit Trastevere, a popular neighborhood in Vatican City. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

A blend of family-friendly attractions, romantic experiences, and scenic views await you in Rome on today’s itinerary. First up is the wondrous art museum, Vatican Museums. Afterward, continue to Sistine Chapel, a chapel every traveler should visit.

As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to St. Peter's Basilica. This world-famous major basilica is an essential stop. Following that, head to Piazza Di Spagna, another must-visit site that will enhance your experience. Don’t forget to stop by Spanish Steps, an extraordinary public square in the city.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

To truly maximize your evening out, consider visiting Sant' Eustachio Caffè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Yellowsquare Rome, another bar with an inviting ambiance. Similarly, Caffè Portofino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 7

Day 7

  • Rome
  • Brindisi
  • More

Drive 791 km, 8 hours 27 min

  • Well of St Patrick
  • Torre del Moro Orvieto
  • More

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Orvieto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Brindisi. You’ll stay here for 1 night.

Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Well Of St. Patrick. This culturally significant monument is sure to ignite your curiosity. Next, dive into the picture-perfect features of Torre Del Moro Orvieto, a must-visit monument in the village.

At the end of the day, you will drive to Brindisi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Brindisi's best restaurants.

Treat yourself to a delightful dinner at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bento? It's another excellent option with a diverse menu. Consider reserving a table at Cozza Nera as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Brindisi.

Say good night to Brindisi and look forward to another great day of your road trip in Italy!

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Day 8

Day 8

  • Brindisi - Departure day
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  • Saint Pietro of Schiavoni Archeologica Area
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Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Saint Pietro Of Schiavoni Archeologica Area. This up-and-coming archeological site is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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