One-Week Italy Road Trip from Venice traveling south to Florence, Siena, Rome, and Arezzo

On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Venice. In the evening, you’ll end up in Florence, where you will stay for 1 night.

Start your sightseeing with a visit to Piazza San Marco. This square is rated an average of 4.7 out of 5 stars from 152,982 visitors.

St Mark's Basilica is another popular attraction you could visit today. This cathedral has a rating of 4.7 out of 5 stars from 18,439 visitors.

Doge's Palace is also highly recommended by travelers. More than 318,104 people visit this top attraction every year. This palace has a rating of 4.7 out of 5 stars from 24,775 visitors.

Bridge Of Sighs is an attraction you won’t want to miss. This footbridge is rated an average of 4.6 out of 5 stars in 18,223 reviews.

When you’re done exploring for the day, you’ll drive to Florence, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Begin your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative, and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Il Palagio, a top local spot known for its tantalizing italian contemporary menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Archea Brewery provides a great setting to enjoy the night away.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Florence, and Pisa. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 1 night.

Seize the day by visiting some of the best attractions in the area, like Piazza Della Signoria. This extraordinary square has an average rating of 4.8 out of 5 stars from 66,956 visitors.

Next, make your way to Ponte Vecchio. This deck arch bridge is rated an average of 4.7 out of 5 stars in 118,099 reviews.

While in Florence, we also recommend a visit to Piazzale Michelangelo. This square has been rated an average of 4.8 out of 5 stars in 77,744 reviews.

Continue your road trip and head to your next destination, Pisa. This car ride takes around 1 hour 19 min.

A top pick for your self-guided sightseeing tour today is Leaning Tower Of Pisa. Over 3,200,000 travelers visit this attraction every year. Previous visitors have rated this bell tower an average of 4.7 out of 5 stars in 116,882 reviews.

Piazza Del Duomo, Pisa is a local recommendation that you also can pay a visit today. This square is rated an average of 4.7 out of 5 stars in 104,550 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to book a table at Antica Trattoria Papei, a popular restaurant in Siena. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Siena at Osteria Quattro Venti, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Osteria da Divo. As a dining spot that gains high praise from guests, it’s an ideal choice to enhance your time to Siena tonight.

Round off your dining experience by visiting Meet Life Cafè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Maudit Pub, a bar catering to every mood and preference. Bar Impero Siena likewise offers a unique atmosphere, perfect for a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 2 nights here for some well-deserved relaxation.

When you’re ready to jump back into the car and say goodbye to Siena, you’ll hit the road in the direction of Vatican City, Vatican City. Witness the landscapes transform as you cross the border to Vatican City. This drive usually takes around 2 hours 40 min. When you arrive, enjoy some sightseeing.

Drop by the renowned Sistine Chapel. This popular chapel has been rated an average of 4.7 out of 5 stars by 52,083 visitors.

Another unforgettable place to experience is St. Peter's Basilica. Rated 4.8 out of 5 stars by 131,043 visitors, this major basilica deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Saint Peter's Square. This square has been rated an average of 4.8 out of 5 stars in 38,954 reviews.

Another favorite attraction in the area is Vatican Museums, drawing over 1,612,530 yearly visitors. This art museum and popular place of interest enjoys a rating of 4.6 out of 5 stars from 133,310 local and international travelers.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Discover the culinary delights of Rome by securing a reservation at La Pergola. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of mediterranean, and contemporary cuisine. For an alternative dining experience, try Il Pagliaccio, renowned for its delicious creative, and innovative dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Enoteca La Torre, a highly recommended local eatery celebrated for its mouthwatering mediterranean, and creative menu. With its 2-star Michelin recognition, it offers an unforgettable dining adventure.

Explore the vibrant nightlife at La Botticella Of Poggi Giovanni after your meal, a hub for lively evenings and memorable moments. Or, head to Sant' Eustachio Caffè for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

Celebrate another amazing day of your road trip adventure in Italy!

Day 5 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Start your sightseeing with a visit to Colosseum. This roman amphitheatre is a popular stop on travelers’ itineraries in Rome, with an average rating of 4.7 out of 5 stars by 328,821 visitors. Around 7,400,000 people visit this attraction every year.

Roman Forum is another popular place of interest you can visit today. The average rating of 4.7 out of 5 stars from 114,450 reviews gives you an idea of other visitors’ experience at this attraction.

If it’s still bright and early, make your way to Pantheon. Visitors have rated this roman temple an average of 4.8 out of 5 stars in 189,682 reviews. Pantheon receives around 30,000,000 visitors every year.

Piazza Navona is another unique site you can experience today. This attraction is a square rated an average of 4.7 out of 5 stars in 158,771 reviews.

Make your way to the fantastic Castel Sant'angelo, perhaps the most famous museum in Rome. This attraction welcomes around 918,591 visitors annually and is rated 4.7 out of 5 stars by 72,431 travelers.

Your discoveries in Rome do not have to stop there. Check out the fantastic selection of tours and tickets offered in Rome on this day of your trip. You can select your tours below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at DEROMA - Farine Romane, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Rome this evening.

If you’re not ready to end the night just yet, The Apartment Bar Roma offers a perfect venue to relax and savor a drink. Similarly, Hotel Hassler Roma is well-suited for those looking to unwind in a social setting.

Relax and recharge in preparation for another adventurous day in Italy!

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Arezzo. You’ll stay here for 1 night.

Begin your sightseeing with a visit to Altare Della Patria. This architectural structure gets 1,683,070 visitors each year and is rated an average of 4.8 out of 5 stars in 49,843 reviews.

Next up, make your way to Trevi Fountain. This sculpture has an average rating of 4.8 out of 5 stars from 343,494 reviews.

When you’re ready for your next sight of the day, continue to Piazza Di Spagna. This square has an average rating of 4.7 out of 5 stars from 113,658 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit Piazza Del Popolo. This square is rated an average of 4.6 out of 5 stars by 89,807 visitors.

If you’re keen to explore even more, then consider a visit to Villa Borghese. This urban zone of rome is a much-appreciated attraction with an average rating of 4.6 out of 5 stars from 69,749 visitors.

When you’re done exploring for the day, you’ll drive to Arezzo, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Arezzo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Have a memorable dining experience in Arezzo by booking a table at Octavin, renowned as a 1-star Michelin restaurant presenting an exceptional creative menu. Immerse yourself in the culinary delights of La Clandestina, a popular restaurant in Arezzo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Keep the evening going at Liquid Bar, a great choice for enjoying the after-dinner hours with a drink.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Bologna. At the end of the day, you will enjoy the comforts of a top-rated hotel in Venice, which will be your home away from home for 1 night.

Fasten your seatbelt and make your way to your next stop. Bologna, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Arezzo to Bologna may take around 2 hours 9 min without traffic disruptions. Upon arrival in Bologna, we highly recommend checking out some of the top attractions.

Make Palazzo D'accursio your first stop of the day. Previous visitors have rated this palazzo an average of 4.6 out of 5 stars in 969 reviews.

Next up, make a stop at Piazza Maggiore. With an average rating of 4.7 out of 5 stars by 64,523 visitors, it's easy to understand why so many people visit this square every year.

Two Towers is another attraction you can visit on this day of your vacation. This tower has an average rating of 4.7 out of 5 stars by 25,975 visitors.

When you’re finished at Two Towers, the perfect next stop is Piazza Santo Stefano. This square is rated an average of 4.8 out of 5 stars in 7,617 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Start your culinary exploration in Venice by securing a reservation at Local. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of contemporary cuisine. For another dining delight, visit Wistèria, celebrated for its delectable contemporary, and venetian menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Quadri, a top local spot known for its tantalizing modern menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Unwind after your meal by stepping into The Irish Pub Venezia. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Dolce Vita Venezia offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Devils Forest Pub, another top-rated bar in the area.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.