9-Day Italy Road Trip from Rome to Siena, Florence, and Perugia

Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay in Rome for 3 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Altare della Patria or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Rome. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Discover the culinary delights of Rome by securing a reservation at La Pergola. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of mediterranean, and contemporary cuisine. For an alternative dining experience, try Il Pagliaccio, renowned for its delicious creative, and innovative dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Enoteca La Torre, a highly recommended local eatery celebrated for its mouthwatering mediterranean, and creative menu. With its 2-star Michelin recognition, it offers an unforgettable dining adventure.

Following your dinner, dive into the local bar culture at La Botticella of Poggi Giovanni. Alternatively, go to Sant' Eustachio Caffè, the perfect place for those looking to experience the best of the nightlife. Similarly, Caffè Portofino provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise a toast to the start of your 9-day road trip in Italy!

Day 2 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Begin your sightseeing with a visit to Trevi Fountain. This extraordinary sculpture is rated an average of 4.8 out of 5 stars by 343,494 visitors.

Next, make your way to Piazza di Spagna. This top attraction is a square with an average rating of 4.7 out of 5 stars by 113,658 visitors.

We also recommend a visit to Spanish Steps. This monumental staircase is rated 4.5 out of 5 stars by 57,211 travelers.

If you’re keen to keep exploring, visit piazza del Popolo. This highly recommended sightseeing destination has received an average rating of 4.6 out of 5 stars from 89,807 travelers.

Today is also your chance to spend some time at Villa Borghese. This urban zone of rome is rated an average of 4.6 out of 5 stars by 69,749 travelers.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

As a top-rated it is an ideal choice in the city. Enjoy a lovely meal at DEROMA - Farine Romane, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Taverna Italiana is another top choice with a popular menu. You could also check for a table at Centro. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

Keep the evening going at The Apartment Bar Roma, a great choice for enjoying the after-dinner hours with a drink. You could also go to Hotel Hassler Roma, which offers a similarly pleasant setting and great drinks.

Raise your glass to another unforgettable day in Italy!

Day 3 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Journey into the unknown at Castel Sant'Angelo, a unique attraction awaiting your visit. This remarkable museum has an average rating of 4.7 out of 5 stars from 72,431 reviews. Every year, Castel Sant'Angelo welcomes more than 918,591 curious visitors.

When you’re ready to continue your sightseeing, Piazza Navona is a recommended place to visit. This square is rated an average of 4.7 out of 5 stars in 158,771 reviews.

Another must-see attraction in Rome is Pantheon. This spectacular roman temple gets over 30,000,000 visitors every year. Rated an average of 4.8 out of 5 stars by 189,682 travelers, this popular tourist destination in Rome offers an experience you will remember.

Roman Forum is another popular stop on travelers' itineraries in Rome. This square promises memorable moments of exploring. Other travelers have rated this attraction 4.7 out of 5 stars in 114,450 reviews.

Lastly, don't miss out on Colosseum. Rated 4.7 out of 5 stars by 328,821 local and international travelers, it's a popular place to visit. This roman amphitheatre gets closer to 7,400,000 visits every year.

There are plenty of experiences you can choose from in Italy that will add excitement to your vacation. When you’re keen to discover what else Rome has in store for you, use this day to go on a tour. Scroll down and select tours and activities to include on your itinerary for the day.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Ristorante Tema, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Maccheroni, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of RoYaL Art Cafè Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Celebrate another amazing day of your road trip adventure in Italy!

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Vatican City.

Make St. Peter's Basilica one of your first sightseeing stops in Vatican City. Rated an average of 4.8 out of 5 stars by 131,043 travelers, a visit to this local attraction makes for a great introduction to the area. This major basilica attracts 11,000,000 visitors every year.

Sistine Chapel is a worthwhile attraction you can visit next. This chapel is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 52,083 reviews.

Today is also the perfect opportunity to drop by Saint Peter's Square. This square has been rated an average of 4.8 out of 5 stars by 38,954 visitors.

If you’re keen to explore more, head to Vatican Museums and find out why 1,612,530 people visit this spot every year. A trip to this popular art museum is also your opportunity to see if it lives up to the reputable 4.6 out of 5-star rating as given by 133,310 previous visitors.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Siena. Siena offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Treat yourself to a delightful dinner at Antica Trattoria Papei, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Osteria Quattro Venti? It's another excellent option with a diverse menu. Consider reserving a table at Osteria da Divo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

Continue your lively evening at Meet Life Cafè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Maudit Pub is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Impero Siena ensures a night out tailored to your taste.

Relax and recharge in preparation for another adventurous day in Italy!

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena, and Pisa. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Begin your sightseeing with a visit to piazza del Campo. This extraordinary square is rated an average of 4.8 out of 5 stars by 64,175 visitors.

Next, make your way to Siena Cathedral. This top attraction is a domus with an average rating of 4.8 out of 5 stars by 21,656 visitors.

When you’re ready to jump back into the car and say goodbye to Siena, you’ll hit the road in the direction of Pisa. This drive usually takes around 1 hour 48 min. When you arrive, enjoy some sightseeing.

Begin your sightseeing with a visit to Piazza del Duomo, Pisa. This extraordinary square is rated an average of 4.7 out of 5 stars by 104,550 visitors.

Next, make your way to Leaning Tower of Pisa. This top attraction is a bell tower with an average rating of 4.7 out of 5 stars by 116,882 visitors. Leaning Tower of Pisa welcomes 3,200,000 yearly visitors.

We also recommend a visit to Angelo Caduto. This point of interest is rated 4.5 out of 5 stars by 150 travelers.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative, and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gucci Osteria da Massimo Bottura. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary, and international cuisine in the city.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, SE·STO on Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Archea Brewery is also a great option that provides a perfect setting for a relaxing evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

Day 6 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Start your sightseeing with a visit to Galleria dell'Accademia. This national museum is rated an average of 4.6 out of 5 stars from 34,429 visitors. Galleria dell'Accademia welcomes around 1,719,645 visitors every year.

Cathedral of Santa Maria del Fiore is another popular attraction you could visit today. This church has a rating of 4.8 out of 5 stars from 76,359 visitors.

Central Market is also highly recommended by travelers. This sightseeing destination has a rating of 4.4 out of 5 stars from 43,100 visitors.

Basilica di Santa Maria Novella, Firenze (FI) is an attraction you won’t want to miss. This archives is rated an average of 4.7 out of 5 stars in 23,075 reviews.

One of the most unique ways of discovering what else Florence has to offer is by going on a top-rated tour. Be sure to check out all the experiences Florence offers and add your favorites to your Italy travel package below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Trattoria Da Burde, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Ristorante Buca Mario, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Florence this evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.

Seize the day by visiting some of the best attractions in the area, like piazza della Signoria. This extraordinary square has an average rating of 4.8 out of 5 stars from 66,956 visitors.

Next, make your way to Ponte Vecchio. This deck arch bridge is rated an average of 4.7 out of 5 stars in 118,099 reviews.

While in Florence, we also recommend a visit to Uffizi Gallery. Hosting around 2,011,219 visitors every year, Uffizi Gallery is one of the best places to visit. This national museum has been rated an average of 4.7 out of 5 stars in 61,794 reviews.

If you’re keen to explore even more, then consider a visit to Basilica of Santa Croce in Florence. With an average rating of 4.7 out of 5 stars by 28,544 travelers, this church is a highly recommended stop on your sightseeing around Florence.

Make your way to piazzale Michelangelo, perhaps the most famous square in Florence. This attraction is rated an average of 4.8 out of 5 stars in 77,744 reviews.

When you’re done exploring for the day, you’ll drive to Perugia, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Perugia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at Ristorante Settimo Sigillo, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Bar Pellas, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Taverna. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Perugia this evening.

If you’re not ready to end the night just yet, Tommi Bar offers a perfect venue to relax and savor a drink. Similarly, Valentina is well-suited for those looking to unwind in a social setting. Caffe Dal Perugino is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 1 night here for some well-deserved relaxation.

When you’ve had your share of Perugia, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Santa Maria degli Angeli. Your travel time is around 25 min.

Start your sightseeing with a visit to Basilica of Santa Maria degli Angeli. This papal basilica is rated an average of 4.8 out of 5 stars from 19,258 visitors.

Santa Maria degli Angeli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Santa Maria degli Angeli behind. This drive usually takes around 11 min. Santa Maria degli Angeli welcomes you with a multitude of unique vacation experiences.

A top pick for your self-guided sightseeing tour today is Basilica di Santa Chiara. Previous visitors have rated this minor basilica an average of 4.7 out of 5 stars in 9,628 reviews.

Piazza del Comune is a local recommendation that you also can pay a visit today. This point of interest is rated an average of 4.6 out of 5 stars in 3,057 reviews.

Another attraction you won't want to miss is Basilica of San Francesco d'Assisi. This papal basilica is rated an average of 4.9 out of 5 stars in 33,258 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Harry's Bar, a highly-rated dining destination in Rome. If you're eager to try something different, consider Ristorante Amedeo, another top spot with a tantalizing menu. You might also want to secure a reservation at VinAllegro. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Rome this evening.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Day 9 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Make the most of your final day in Italy by visiting Rome’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.

Start your sightseeing with a visit to Campo de' Fiori. This square is rated an average of 4.4 out of 5 stars from 51,133 visitors.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

This renowned restaurant holds and offers an exceptional menu of cuisine.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!