10-Day Spain Self-Drive Road Trip With Itinerary from Madrid traveling north to Avila, Leon, Santander, and Valladolid

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Explore the best of Spain on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Madrid, Avila, Salamanca, Leon, Gijon, Santander, Portugalete, Bilbao, Villaescusa, Valladolid, and Segovia. This road trip itinerary in Spain seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Spain takes you through some of the best places to see in the country. You will spend 4 nights in Madrid, 1 night in Avila, 1 night in Leon, 2 nights in Santander, and 1 night in Valladolid. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Madrid, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. El Retiro Park and Main Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Santiago Bernabéu Stadium, learn more about the unique Market Of San Miguel, and immerse yourself in the vibrant atmosphere of Museo Del Prado.

As you hit the open road and drive through Madrid, Avila, Salamanca, Leon, Gijon, Santander, Portugalete, Bilbao, Villaescusa, Valladolid, and Segovia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

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Day 1

Day 1

  • Madrid - Arrival day
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  • La Latina
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Say hello to Madrid! Your exciting road trip through Spain is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Madrid for 3 nights before you continue your adventure!

Madrid is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out La Latina, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Madrid. Check-in typically starts around 2 to 4 PM at hotels in Spain. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Madrid, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Restaurante Taberna Madrid Madriz, a top-rated dining destination in Madrid. If you're in the mood to try something new, consider Lamucca del Carmen, another top spot with a mouthwatering menu. You might also want to secure a reservation at El miniBAR. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Madrid this evening.

Keep the evening going at Bar Yambala, a great choice for enjoying the after-dinner hours with a drink. You could also go to Baton Rouge Cocktail Bar, which offers a similarly pleasant setting and great drinks. Another option is Cafe Madrid, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 10-day road trip in Spain!

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Day 2

Day 2

  • Madrid
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Drive 6 km, 42 min

  • Main Square
  • Market of San Miguel
  • Royal Palace of Madrid
  • plaza de España
  • Temple of Debod
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Day 2 of your road trip across Spain promises a magnificent time exploring Madrid. You have 2 nights left in Madrid. Take the opportunity to experience more of the best attractions and activities in the city.

Prepare for a day full of fun adventures, romantic experiences, and breathtaking views. When you’re ready, kick off your sightseeing adventure at Main Square. This world-famous public square is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Market Of San Miguel, one of the city’s best highlights.

Next, check out Royal Palace Of Madrid, one of the most iconic places to see in Madrid. This palace is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Plaza De España. Wander around and soak in the detailed atmosphere this public square offers. Then, head to Temple Of Debod, a top-rated monument that adds another dimension to your day.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Spain is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Madrid's best restaurants.

Experience a symphony of flavors at DiverXO in Madrid by securing a reservation in advance. Renowned for its 3-star Michelin distinction, DiverXO delights its guests with its exceptional variety of meals showcasing delicious creative cuisine. For a palate-pleasing alternative, make sure to dine at Smoked Room, acclaimed for its delectable contemporary specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Paco Roncero, a top-rated restaurant known for its outstanding menu. Known as a top-rated 2-star Michelin establishment, it's a top choice for creative cuisine in the city.

Continue your lively evening at Jazz Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. España Building is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, 1862 Dry Bar ensures a night out tailored to your taste.

Take some time to reflect on your day and savor another beautiful night in Spain.

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Day 3

Day 3

  • Madrid
  • More

Drive 28 km, 1 hour 35 min

  • Santiago Bernabéu Stadium
  • Crystal Palace
  • El Retiro Park
  • Museo Nacional Centro de Arte Reina Sofía
  • Casa de Campo
  • More

On day 3 of your road trip, you will have an entire day to explore Madrid. You’ll stay in Madrid for 1 night and discover all the best things to see and do in the area.

Discover a day packed with family-friendly attractions, scenic views, and picturesque spots in Madrid. Begin your sightseeing with Santiago Bernabéu Stadium. This timeless stadium is one of the top attractions in the city. Proceed to Crystal Palace, another must-visit attraction.

As you wander through the inviting streets of Madrid, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to El Retiro Park. This iconic park is a traveler-favorite. Not far away, you’ll find Museo Nacional Centro De Arte Reina Sofía, another key site on your sightseeing itinerary. Casa De Campo is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Spain is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Experience shopping bliss at Madrid as you explore Salamanca District. Take a leisurely stroll through unique boutiques and high-end shops, where local treasures are waiting to be found. Beyond shopping, Salamanca District offers more options, including unique attractions, key services, and vibrant events.

As you explore more of Madrid, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at Areia, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La MaMá Restaurante is another top choice with a popular menu. You could also check for a table at Sacha Restaurant. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Madrid tonight.

Raise your glass to another unforgettable day in Spain!

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Day 4

Day 4

  • Madrid
  • Ávila
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Drive 122 km, 1 hour 52 min

  • Thyssen-Bornemisza Museum
  • Museo del Prado
  • Puerta de Alcalá
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Experience an unparalleled adventure on day 4 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Madrid. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Avila. You will spend 1 night here for some well-deserved relaxation.

Today, you'll explore some of the most beautiful places in Madrid, including a museum and a monument. Start your day with a visit to Thyssen-bornemisza Museum. This well-known museum is a must-visit in the city. When you’re ready for your next discovery, continue to Museo Del Prado, which may be one of the most heritage-rich places you will experience today.

One of the best things about exploring Madrid on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Puerta De Alcalá, a widely recognized monument in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Avila. Avila offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Avila. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Discover the culinary delights of Avila by securing a reservation at Barro. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of creative cuisine. Alternatively, Restaurante Sanjuaniego beckons with its unique menu offerings.

Continue your lively evening at Bar La Mezquita, a perfect place for winding down or revving up the night, depending on which mood you’re in. La Oca Cocktail Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, The Black Rose ensures a night out tailored to your taste.

Raise your glass to another unforgettable day in Spain!

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Day 5

Day 5

  • Ávila
  • León
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Drive 316 km, 3 hours 18 min

  • Ávila Cathedral
  • Walls of Ávila
  • Salamanca Cathedral
  • Calisto and Melibea Vegetable Garden
  • More

Embark on another extraordinary experience on day 5 of your road trip in Spain. Today, you will make 2 stops and experience some of the highlights of Avila and Salamanca. At the end of the day, you will enjoy the comforts of a top-rated hotel in Leon, which will be your home away from home for 1 night.

Prepare for a day full of fun adventures, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Ávila Cathedral. This intriguing church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Walls Of Ávila, one of the city’s best highlights.

Next, check out Salamanca Cathedral, one of the most locally renowned places to see in Avila. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Calisto And Melibea Vegetable Garden. Wander around and soak in the romantic atmosphere this botanical garden offers.

When you’re done exploring for the day, you’ll drive to your hotel in Leon. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Leon's best restaurants.

Start your culinary exploration in Leon by securing a reservation at Becook. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of fusion and modern cuisine. For another dining delight, visit Pablo, celebrated for its delectable modern menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Cocinandos, a top local spot known for its tantalizing modern menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Cap off your dinner by heading to Café Bar La Dama, ideal for a leisurely evening with a drink in hand. Bacanal is another bar that offers an enjoyable setting. Similarly, Bar Chelsea is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another amazing day of your road trip adventure in Spain!

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Day 6

Day 6

  • León
  • Santander
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Drive 322 km, 3 hours 42 min

  • Catedral de León
  • park of El Cid
  • Basilica of San Isidoro
  • San Lorenzo Beach
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Dive into day 6 of your remarkable road trip in Spain. Today you will explore Leon and Gijon, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Santander. You’ll stay here for 2 nights.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, romantic experiences, and breathtaking views. Whether you decide to explore Leon on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. León Cathedra is the first of them. Spend some time admiring this culturally significant church before continuing your journey. Park Of El Cid is your next stop. This curiosity-inducing park is one of the best-rated sights in Leon.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Basilica Of San Isidoro. This culturally significant church is a sight to behold. To round off your sightseeing experience, visit San Lorenzo Beach.

At the end of the day, you will drive to Santander, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Santander. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Santander by booking a table at Cadelo, renowned as a Bib Gourmand restaurant presenting an exceptional modern menu. For a different culinary experience in Santander, Umma shines as one of the top destinations, known for its delicious modern cuisine. This Bib Gourmand-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Agua Salada is known as a top local spot for its delicious contemporary and traditional cuisine in Santander. This Bib Gourmand awardee is a highly recommended choice for an unforgettable meal.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Kings Pub, a well-loved spot among locals and tourists. Or, head to Grog. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Hygge Cocktail, another top-rated place in the area.

Say good night to Santander and look forward to another great day of your road trip in Spain!

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Day 7

Day 7

  • Santander
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Drive 207 km, 3 hours 7 min

  • Vizcaya Bridge
  • Federiko Moiua enparantza
  • Doña Casilda Iturrizar park
  • Puppy
  • Guggenheim Museum
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Greet day 7 of your road trip in Spain with a smile and start your day with a hearty breakfast. You will return to Santander for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Portugalete and Bilbao.

Set out on a day brimming with family-friendly attractions, breathtaking views, and picturesque spots. Start at the notable Vizcaya Bridge, a culturally significant monument in Santander. Next, go to Federico Moyúa Enparantza.

After visiting Vizcaya Bridge and Federico Moyúa Enparantza, have a stroll along Santander's streets and take in the local charm. Continue your sightseeing by heading to Doña Casilda Iturrizar Park. This romantic park offers a unique experience. Puppy is another noteworthy attraction worthwhile a visit.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Santander.

As you explore more of Santander, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Restaurante Agua Salada, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Restaurante Matices Santander? It's another excellent option with a diverse menu. Consider reserving a table at La Enmienda Dieciocho as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Santander.

Let the evening flow smoothly from dinner to drinks at Little Bobby, a top-rated bar in the area.

Head back to your accommodation in Santander and get some rest in preparation for another magical day of your road trip in Spain!

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Day 8

Day 8

  • Santander
  • Valladolid
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Drive 273 km, 3 hours 16 min

  • Mercado del Este
  • Botin Centre
  • Palacio de la Magdalena
  • Cabarceno Natural Park
  • More

On day 8 of your road trip in Spain, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Santander and Villaescusa. In the evening, you’ll end up in Valladolid, where you will stay for 1 night.

Get ready to discover some of the most iconic wonders in Santander, including a market, an art gallery, a palace, a safari park and much more! Start your day at Mercado Del Este. This standout market is a worthwhile place to see in Santander. Then, wander over to Centro Botin. If detailed sites excite you, this art gallery will be right up your alley. Nearby, you’ll also find Palacio De La Magdalena. This visually striking palace is a favorite among visitors.

Santander offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Cabarceno Natural Park is a famous spot in the city that will captivate you with its unique charm.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Valladolid. Valladolid offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Valladolid, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to an extraordinary dining experience at Llantén, a Bib Gourmand restaurant offering an incredible traditional menu. Alternatively, if your taste buds call for something different, Alquimia - Laboratorio is one of the best restaurants for creative and modern cuisine in Valladolid. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Trigo. As a top-rated establishment with 1 Michelin star, it is an ideal choice for modern cuisine in the city.

Following your dinner, dive into the local bar culture at Bar Panoramix. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bar Esgueva, the perfect place for those looking to experience the best of the nightlife. Similarly, Largo Adiós provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Head back to your accommodation in Valladolid and get some rest in preparation for another magical day of your road trip in Spain!

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Day 9

Day 9

  • Valladolid
  • Madrid
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Drive 211 km, 3 hours 4 min

  • Parque Campo Grande
  • Alcázar of Segovia
  • Segovia Cathedral
  • Aqueduct of Segovia
  • More

On day 9 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 2 destinations, Valladolid and Segovia. When you’re not sightseeing, take time to relax at your selected hotel in Madrid, where you’ll be staying for 1 night.

Today’s agenda in Valladolid includes a park, a castle, a church, a monument and much more! Parque Campo Grande is must-visit park and a great starting point for the day. Next, continue your journey to Alcázar Of Segovia, an extraordinary castle, located just a leisurely stroll away. Next, head to Segovia Cathedral, a monumental church, also available for your discovery today.

When you’re done exploring for the day, you’ll drive to your hotel in Madrid. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Madrid's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Taberna Mozárabe, an excellent option for tonight's dining. Looking for something different? Restaurante Lakasa offers a tantalizing alternative with its diverse menu. And don’t miss Lambuzo. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Madrid.

Take some time to reflect on your day and savor another beautiful night in Spain.

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Day 10

Day 10

  • Madrid - Departure day
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  • Western Park
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Day 10 of your road trip in Spain is your departure day. This is your chance to catch a last glimpse of Madrid before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Parque Del Oeste, a mesmerizing park before you head out.

As your final day in Spain unfolds, enjoy a last-minute shopping spree in Madrid's best shopping area, Plaza Mayor. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Spain.

Before you conclude your road trip in Spain, drop by another restaurant for a last chance at a memorable dining experience in Madrid.

If you're in the mood for something new, try Mas Al Sur, another premier location with a delectable menu.

You’ll then say farewell to Madrid. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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