10-Day Spain Self-Drive Road Trip With Itinerary from Madrid traveling north to Avila, Leon, Santander, and Valladolid

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Experience the freedom of the open road in Spain as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Madrid, Avila, Salamanca, Leon, Gijon, Santander, Portugalete, Bilbao, Villaescusa, Valladolid, and Segovia.

This perfectly planned road trip itinerary in Spain takes you through some of the best places to see in the country. You will spend 4 nights in Madrid, 1 night in Avila, 1 night in Leon, 2 nights in Santander, and 1 night in Valladolid. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Madrid, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. El Retiro Park and Main Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Santiago Bernabéu Stadium, learn more about the unique Market Of San Miguel, and immerse yourself in the vibrant atmosphere of Museo Del Prado.

As you hit the open road and drive through Madrid, Avila, Salamanca, Leon, Gijon, Santander, Portugalete, Bilbao, Villaescusa, Valladolid, and Segovia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
La Latina
Main SquareMarket of San MiguelRoyal Palace of Madridplaza de EspañaTemple of Debod
Santiago Bernabéu StadiumCrystal PalaceEl Retiro ParkMuseo Nacional Centro de Arte Reina SofíaCasa de Campo
Thyssen-Bornemisza MuseumMuseo del PradoPuerta de Alcalá
Ávila CathedralWalls of ÁvilaSalamanca CathedralCalisto and Melibea Vegetable Garden
Catedral de Leónpark of El CidBasilica of San IsidoroSan Lorenzo Beach

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Day 1

Day 1

  • Madrid - Arrival day
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  • La Latina
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Say hello to Madrid! Your exciting road trip through Spain is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Madrid for 3 nights before you continue your adventure!

Madrid is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out La Latina, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Madrid. Check-in typically starts around 2 to 4 PM at hotels in Spain. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Madrid, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Restaurante Taberna Madrid Madriz, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Lamucca del Carmen offers an enticing alternative with its varied menu. Additionally, El miniBAR is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Madrid.

After your meal, keep the night alive at a bar like Bar Yambala, known for its lively atmosphere. Baton Rouge Cocktail Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Cafe Madrid offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 10-day road trip in Spain!

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Day 2

Day 2

  • Madrid
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Drive 6 km, 42 min

  • Main Square
  • Market of San Miguel
  • Royal Palace of Madrid
  • plaza de España
  • Temple of Debod
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On day 2 of your road trip, you will have an entire day to explore Madrid. You’ll stay in Madrid for 2 nights and discover all the best things to see and do in the area.

A blend of family-friendly attractions, romantic experiences, and scenic views await you in Madrid on today’s itinerary. First up is the world-famous public square, Main Square. Afterward, continue to Market Of San Miguel, a food market every traveler should visit.

As you explore Madrid’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Royal Palace Of Madrid. This iconic palace is an essential stop. Following that, head to Plaza De España, another must-visit site that will enhance your experience. Don’t forget to stop by Temple Of Debod, a famous monument in the city.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Spain is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Madrid, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Experience a taste of local culinary excellence while in Madrid by securing a table at DiverXO. An esteemed 3-star Michelin restaurant, it features an exceptional creative menu. For an alternative taste experience, visit Smoked Room, famous for its scrumptious contemporary dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Paco Roncero, a local favorite celebrated for its exquisite creative cuisine in Madrid. Located in the heart of the city, this 2-star Michelin restaurant is an ideal pick for creative cuisine lovers seeking top-notch culinary experiences.

Continue your lively evening at Jazz Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. España Building is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, 1862 Dry Bar ensures a night out tailored to your taste.

Relax and reminisce about your day in Spain and look forward to more memorable moments to come!

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Day 3

Day 3

  • Madrid
  • More

Drive 28 km, 1 hour 35 min

  • Santiago Bernabéu Stadium
  • Crystal Palace
  • El Retiro Park
  • Museo Nacional Centro de Arte Reina Sofía
  • Casa de Campo
  • More

Day 3 of your road trip will take you to the best attractions Madrid has to offer. Cherish the 1 night you have left in Madrid by discovering the best things there are to see and do in the city.

Discover a day packed with fun adventures, scenic views, and photo-friendly spots in Madrid. Begin your sightseeing with Santiago Bernabéu Stadium. This timeless stadium is one of the top attractions in the city. Proceed to Crystal Palace, another must-visit attraction that enhances the city’s allure.

As you wander through the inviting streets of Madrid, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to El Retiro Park. This globally renowned park is a traveler-favorite. Not far away, you’ll find Museo Nacional Centro De Arte Reina Sofía, another key site on your sightseeing itinerary. Conclude your day at Casa De Campo and uncover why it's recognized as one of the city's most spectacular attractions.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Spain is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Experience shopping bliss at Madrid as you explore Gran Via. Take a leisurely stroll through unique boutiques and shops, where local treasures are waiting to be found. Beyond shopping, Gran Via offers more options, including restaurants, unique attractions, key services, and vibrant events.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Madrid. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Areia, an iconic dining spot in Madrid. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La MaMá Restaurante, a popular restaurant in Madrid. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sacha Restaurant, a hidden gem nestled in Madrid. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Spain.

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Day 4

Day 4

  • Madrid
  • Ávila
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Drive 122 km, 1 hour 52 min

  • Thyssen-Bornemisza Museum
  • Museo del Prado
  • Puerta de Alcalá
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Experience an unparalleled adventure on day 4 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Madrid. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Avila. You will spend 1 night here for some well-deserved relaxation.

Set out on a day brimming with fun adventures, photo-friendly spots, and history-rich sites. Start at the popular Thyssen-bornemisza Museum, a heritage-rich museum in Madrid. Next, go to Museo Del Prado.

After visiting Thyssen-bornemisza Museum and Museo Del Prado, take time to explore Madrid's streets and absorb its charm. Continue your sightseeing by heading to Puerta De Alcalá. This visually striking monument offers a unique experience.

At the end of the day, you will drive to Avila, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Avila. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Begin your culinary exploration in Avila by securing a reservation at Barro. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of creative cuisine. Or, for a change of pace, Restaurante Sanjuaniego boasts a menu that's sure to impress.

Continue your evening by exploring the vibrant nightlife scene at Bar La Mezquita, a prime destination for a thrilling night out. Also, don’t forget to check out La Oca Cocktail Bar, a bar that offers unique local touches. Likewise, The Black Rose provides an excellent alternative for a fun evening.

Get a good night's sleep and look forward to another great day on the road in Spain!

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Day 5

Day 5

  • Ávila
  • León
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Drive 316 km, 3 hours 18 min

  • Ávila Cathedral
  • Walls of Ávila
  • Salamanca Cathedral
  • Calisto and Melibea Vegetable Garden
  • More

Embark on another extraordinary experience on day 5 of your road trip in Spain. Today, you will make 2 stops and experience some of the highlights of Avila and Salamanca. At the end of the day, you will enjoy the comforts of a top-rated hotel in Leon, which will be your home away from home for 1 night.

Savor the day by visiting some of the best places to see in Avila, including a church, a monument, and a botanical garden. Start your adventure at Ávila Cathedral. This underrated church is a must-visit for travelers looking for a unique holiday experience. Make your way to Walls Of Ávila located in Avila for an enchanting atmosphere.

Next, immerse yourself in the setting of Salamanca Cathedral. Its majestic features will captivate you. After the church, continue your tour of the city with a visit to Calisto And Melibea Vegetable Garden. This botanical garden has an eye-catching appeal.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Leon. Leon offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Leon, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to an extraordinary dining experience at Becook, a Bib Gourmand restaurant offering an incredible fusion and modern menu. Alternatively, if your taste buds call for something different, Pablo is one of the best restaurants for modern cuisine in Leon. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Cocinandos. As a top-rated establishment with 1 Michelin star, it is an ideal choice for modern cuisine in the city.

After savoring a delicious meal, step into the vibrant nightlife at Café Bar La Dama, where the evening is just getting started. In the same way, Bacanal offers a unique charm perfect for experiencing the local bar scene in Leon. Bar Chelsea is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Spain.

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Day 6

Day 6

  • León
  • Santander
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Drive 322 km, 3 hours 42 min

  • Catedral de León
  • park of El Cid
  • Basilica of San Isidoro
  • San Lorenzo Beach
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On day 6 of your road trip in Spain, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Leon and Gijon. In the evening, you’ll end up in Santander, where you will stay for 2 nights.

Brace yourself for today’s incredible lineup of attractions in Leon, featuring family-friendly attractions, romantic experiences, and breathtaking views. Start at León Cathedra, a locally renowned church in the city. Then, head to Park Of El Cid and soak in the ambiance of this peaceful park.

There are many interesting places to see in Leon and when you are ready for more, go to Basilica Of San Isidoro. This is one of the city’s most locally appreciated spots. After exploring the church, visit the locally renowned San Lorenzo Beach.

When you’re done exploring for the day, you’ll drive to your hotel in Santander. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Santander. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dive into a culinary adventure like no other in Santander by booking a table at Cadelo. This popular restaurant holds a Bib Gourmand award and offers an exceptional menu of modern cuisine. For another culinary dining option, venture to Umma, celebrated for its delectable modern menu. This acclaimed Bib Gourmand-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Agua Salada, a top local restaurant known for its tantalizing contemporary and traditional menu. With a Bib Gourmand recognition, it promises an exceptional dining experience not to be missed.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Kings Pub, a well-loved spot among locals and tourists. Or, head to Grog. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Hygge Cocktail, another top-rated place in the area.

Raise your glass and celebrate another amazing day of your road trip in Spain!

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Day 7

Day 7

  • Santander
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Drive 207 km, 3 hours 7 min

  • Vizcaya Bridge
  • Federiko Moiua enparantza
  • Doña Casilda Iturrizar park
  • Puppy
  • Guggenheim Museum
  • More

On day 7 of your road trip, you’ll start and end your day in Santander, where you'll stay for 1 night more.

Bring your curiosity for today’s adventure around Santander. Some of the town’s most loved attractions await. Vizcaya Bridge is the perfect place to start. This monument is one of the most interesting places to visit in Santander.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Doña Casilda Iturrizar Park. This idyllic park offers a unique experience that is highly recommended. Meanwhile, Puppy adds its own distinct charm to your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Santander.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Santander. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Restaurante Agua Salada, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Restaurante Matices Santander offers an enticing alternative with its varied menu. Additionally, La Enmienda Dieciocho is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Santander.

Explore the vibrant nightlife at Little Bobby after your meal, a hub for lively evenings and memorable moments.

Say good night to Santander and look forward to another great day of your road trip in Spain!

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Day 8

Day 8

  • Santander
  • Valladolid
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Drive 273 km, 3 hours 16 min

  • Mercado del Este
  • Botin Centre
  • Palacio de la Magdalena
  • Cabarceno Natural Park
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On day 8 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 2 destinations, Santander and Villaescusa. When you’re not sightseeing, take time to relax at your selected hotel in Valladolid, where you’ll be staying for 1 night.

Get ready for a day filled with fun adventures, photo-friendly spots, and history-rich sites in the charming city of Santander. Your adventure starts at Mercado Del Este, an underrated local hot spot. Another notable attraction to explore is Centro Botin. This popular art gallery is known for its respected appeal.

After soaking in the highlights of these sights, take some time to wander Santander's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Palacio De La Magdalena. This respected palace offers a fascinating experience that many visitors find memorable. Cabarceno Natural Park is also worth visiting.

At the end of the day, you will drive to Valladolid, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Valladolid's best restaurants.

Start your culinary exploration in Valladolid by securing a reservation at Llantén. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of traditional cuisine. For another dining delight, visit Alquimia - Laboratorio, celebrated for its delectable creative and modern menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Trigo, a top local spot known for its tantalizing modern menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Keep the evening going at Bar Panoramix, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bar Esgueva, which offers a similarly pleasant setting and great drinks. Another option is Largo Adiós, which provides an inviting environment for unwinding after a busy day out.

Savor another day of unforgettable experiences in Spain!

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Day 9

Day 9

  • Valladolid
  • Madrid
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Drive 211 km, 3 hours 4 min

  • Parque Campo Grande
  • Alcázar of Segovia
  • Segovia Cathedral
  • Aqueduct of Segovia
  • More

Dive into day 9 of your remarkable road trip in Spain. Today you will explore Valladolid and Segovia, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Madrid. You’ll stay here for 1 night.

Today's adventure in Valladolid promises more breathtaking discoveries and enriching experiences! Begin at Parque Campo Grande. This romantic park is a highlight of any visit in the city. Then, enjoy Alcázar Of Segovia, another enchanting attraction that never fails to captivate visitors. Next, head over to Segovia Cathedral, one of the city’s most interesting attractions, known for its majestic features.

If you’re looking for more, spend time soaking in the atmosphere of Aqueduct Of Segovia. This culturally significant monument is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Madrid. Madrid offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Madrid's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to reserve a table at Taberna Mozárabe, an iconic dining spot in Madrid. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurante Lakasa, a popular restaurant in Madrid. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Lambuzo, a hidden gem nestled in Madrid. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Relax and reminisce about your day in Spain and look forward to more memorable moments to come!

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Day 10

Day 10

  • Madrid - Departure day
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  • Western Park
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Day 10 of your road trip in Spain is your departure day. This is your chance to catch a last glimpse of Madrid before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Parque Del Oeste, a romantic park before you head out.

Make the most of your final day in Spain by visiting Madrid’s iconic markets and shopping establishments in the buzzing Salamanca District. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Spain. You can also browse through boutiques for stylish fashion choices. Elevate your style with pieces from high-end retail stores.

Before you conclude your road trip in Spain, drop by another restaurant for a last chance at a memorable dining experience in Madrid.

If you're in the mood to try something new, consider Mas Al Sur, another top spot with a mouthwatering menu.

You’ll then say farewell to Madrid. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

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