10-Day Spain Self-Drive Road Trip With Itinerary from Santander traveling south to Bilbao, Burgos Province, and Madrid

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Photo of Palacio de la Magdalena aerial panoramic view, located on the Magdalena Peninsula in Santander city, Spain.
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Experience the freedom of the open road in Spain as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Santander, Bilbao, San Sebastian, Ibeas de Juarros, Burgos Province, Madrid, Toledo, and Valladolid.

This perfectly planned road trip itinerary in Spain takes you through some of the best places to see in the country. You will spend 2 nights in Santander, 2 nights in Bilbao, 2 nights in Burgos Province, and 3 nights in Madrid. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Santander, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. El Retiro Park and Main Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Market Of San Miguel, learn more about the unique Museo Del Prado, and immerse yourself in the vibrant atmosphere of Royal Palace Of Madrid.

As you hit the open road and drive through Santander, Bilbao, San Sebastian, Ibeas de Juarros, Burgos Province, Madrid, Toledo, and Valladolid, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

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Day 1

Day 1

  • Santander - Arrival day
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  • Plaza Porticada
  • More

Say hello to Santander! Your exciting road trip through Spain is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Santander for 1 night before you continue your adventure!

Santander is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Plaza Porticada, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Santander. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Santander, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Restaurante la Mayor, a top-rated dining destination in Santander. If you're in the mood to try something new, consider Santa & Co, another top spot with a mouthwatering menu. You might also want to secure a reservation at Marcello Restaurante. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Santander this evening.

Cap off your dinner by heading to Kings Pub, ideal for a leisurely evening with a drink in hand. Grog is another bar that offers an enjoyable setting. Similarly, Hygge Cocktail is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise a toast to the start of your 10-day road trip in Spain!

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Day 2

Day 2

  • Santander
  • Bilbao
  • More

Drive 102 km, 1 hour 50 min

  • Doña Casilda Iturrizar park
  • Guggenheim Museum
  • Puppy
  • Zubizuri
  • Albiako Lorategiak
  • Federiko Moiua enparantza
  • More

On day 2 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 1 destination, Bilbao. When you’re not sightseeing, take time to relax at your selected hotel in Bilbao, where you’ll be staying for 2 nights.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, romantic experiences, and natural wonders. Whether you decide to explore Santander on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Doña Casilda Iturrizar Park is the first of them. Spend some time admiring this serene park before continuing your journey. Guggenheim Museum is your next stop. This extraordinary museum building is one of the best-rated sights in Santander.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Puppy. This picture-perfect art installation is a sight to behold. To round off your sightseeing experience, visit Zubizuri and Albiako Lorategiak.

At the end of the day, you will drive to Bilbao, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Bilbao's best restaurants.

Treat yourself to a delicious dinner at La Viña del Ensanche, an excellent option for tonight's dining. Looking for something different? Marinela jatetxea offers a tantalizing alternative with its diverse menu. And don’t miss San Mamés Jatetxea · Restaurante en San Mamés. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Bilbao.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Boss Bilbao, known for its inviting atmosphere. Stromboli Taberna is another great option if you’re looking for a place to get the night started. Similarly, Zuberoa Taberna provides a great setting to enjoy the night away.

Head back to your accommodation in Bilbao and get some rest in preparation for another magical day of your road trip in Spain!

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Day 3

Day 3

  • Bilbao
  • More

Drive 206 km, 3 hours 5 min

  • Urgull
  • Alderdi Eder Parkea
  • Beach of La Concha
  • Gipuzkoa Plaza
  • Miramar Palace
  • Parte Vieja
  • More

Greet day 3 of your road trip in Spain with a smile and start your day with a hearty breakfast. You will return to Bilbao for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in San Sebastian.

At the top of the list of things to do today is to explore Parte Vieja, a neighborhood that captures the true essence of San Sebastian. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Today’s route brings family-friendly attractions, romantic experiences, and natural wonders. The first attraction of today is Urgull. This worthwhile park is a standout place to see in Bilbao. Continue your discovery at Alderdi Eder Parkea, a romantic park with stories to tell.

As you stroll around Bilbao, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Beach Of La Concha. This popular beach offers a serene encounter with Bilbao. Next, make your way to Gipuzkoa Plaza to add another highlight to your day. After that, visit Miramar Palace, a well-known palace that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Bilbao.

When you’re done exploring for the day, you’ll return to Bilbao and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Bilbao. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Café Iruña, a top recommendation for dinner tonight. Or, for a change of pace, Iturriza Taberna boasts a menu that's sure to impress. Also, be sure to check out Antxoa Taberna. Known as a local hotspot, it’s a great choice for tonight in Bilbao.

Raise your glass and celebrate another amazing day of your road trip in Spain!

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Day 4

Day 4

  • Bilbao
  • Burgos
  • More

Drive 188 km, 2 hours 48 min

  • Atapuerca
  • Cartuja de Miraflores - Burgos
  • Mirador Del Castillo
  • Burgos Cathedral
  • Arco de Santa María
  • Museo de Burgos
  • More

On day 4 of your road trip in Spain, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Ibeas de Juarros and Burgos Province. In the evening, you’ll end up in Burgos Province, where you will stay for 2 nights.

Prepare for a day full of fun adventures, natural wonders, and breathtaking views. When you’re ready, kick off your sightseeing adventure at Atapuerca. This intriguing archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Miraflores Charterhouse, one of the city’s best highlights.

Next, check out Mirador Del Castillo, one of the most up-and-coming places to see in Bilbao. This observation deck is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Burgos Cathedral. Wander around and soak in the romantic atmosphere this church offers. Then, head to Arco De Santa María, a top-rated monument that adds another dimension to your day. Finally, visit the underrated Museo De Burgos, the last of our attraction recommendations for today.

When you’re done exploring for the day, you’ll drive to your hotel in Burgos Province. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Burgos Province. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Restaurante El Fogón de Jesusón, a top-rated dining spot in Burgos Province. If you're in the mood for something new, try Mesón La Cueva, another premier location with a delectable menu. You might also want to book a table at La Quinta del Monje. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Burgos Province.

After your meal, keep the night alive at a bar like Bardeblas, known for its lively atmosphere. Bar San Francisco 7 is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Venezia offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Spain.

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Day 5

Day 5

  • Burgos
  • More

Drive 12 km, 1 hour 8 min

  • The Huelgas Monastery
  • Parque de La Isla
  • Arco de San Gil
  • Museo Histórico Militar de Burgos
  • Iglesia de San Lesmes Abad
  • Iglesia Santa María la Real y Antigua de Gamonal
  • More

Day 5 offers a multitude of experiences. You will stay in Burgos Province for 1 night more, offering you enough time to explore at a relaxed pace.

Today's adventure in Burgos Province promises more breathtaking discoveries and enriching experiences! Begin at Abbey Of Santa María La Real De Las Huelgas. This photogenic monastery is a highlight of any visit in the city. Then, enjoy Parque De La Isla, another romantic attraction that never fails to captivate visitors. Next, head over to Arco De San Gil, one of the city’s most up-and-coming attractions, known for its symbolic features.

If you’re looking for more, spend time soaking in the atmosphere of Museo Histórico Militar De Burgos. This historic military museum is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Iglesia De San Lesmes Abad, a beloved church, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Iglesia Santa María La Real Y Antigua De Gamonal before you head back to your hotel.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Spain is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Burgos Province. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Saciedad Secreta, a top-rated dining destination in Burgos Province. If you're in the mood to try something new, consider El Huerto de Roque, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurante Blue Gallery. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Burgos Province this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to München, known for its inviting atmosphere. Café Bar Comuneros is another great option if you’re looking for a place to get the night started. Similarly, Oslo Café Brewery provides a great setting to enjoy the night away.

Say good night to Burgos Province and look forward to another great day of your road trip in Spain!

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Day 6

Day 6

  • Burgos
  • Madrid
  • More

Drive 249 km, 3 hours

  • Temple of Debod
  • plaza de España
  • Royal Palace of Madrid
  • Market of San Miguel
  • Main Square
  • More

Dive into day 6 of your remarkable road trip in Spain. Today you will explore Madrid, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Madrid. You’ll stay here for 3 nights.

Savor the day by visiting some of the best places to see in Burgos Province, including a monument, a public square, a palace, a food market and much more! Start your adventure at Temple Of Debod. This extraordinary monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Plaza De España located in Burgos Province for another exciting encounter.

Next, immerse yourself in the setting of Royal Palace Of Madrid. Its awe-inspiring features will captivate you. After the palace, continue your tour of the city with a visit to Market Of San Miguel. Visitors usually appreciate the respected features of this food market. Next up is Main Square, a highly recommended public square.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Madrid. Madrid offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Madrid's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Restaurante Taberna Madrid Madriz, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Lamucca del Carmen offers an enticing alternative with its varied menu. Additionally, El miniBAR is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Madrid.

Unwind after your meal by stepping into Bar Yambala. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Baton Rouge Cocktail Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Cafe Madrid, another top-rated bar in the area.

Celebrate another amazing day of your road trip adventure in Spain!

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Day 7

Day 7

  • Madrid
  • More

Drive 7 km, 1 hour 2 min

  • Puerta de Alcalá
  • El Retiro Park
  • Museo del Prado
  • Museo Nacional Centro de Arte Reina Sofía
  • Gran Vía
  • Malasaña
  • More

On day 7 of your road trip, you will have an entire day to explore Madrid. You’ll stay in Madrid for 2 nights and discover all the best things to see and do in the area.

Gran Vía is a fantastic place you can explore today in Madrid. This street is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Madrid-way-of-life and visit all the nearby sights. You should also check out Malasaña, a neighborhood offering more opportunities to enjoy the city’s vibrant atmosphere and landmarks.

Get ready to discover some of the most iconic wonders in Madrid, including a monument, a park, and a museum. Start your day at Puerta De Alcalá. This majestic monument is a spectacular place to see in Madrid. Then, wander over to El Retiro Park. If mesmerizing sites excite you, this park will be right up your alley. Nearby, you’ll also find Museo Del Prado. This visually striking museum is a favorite among visitors.

Madrid offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Museo Nacional Centro De Arte Reina Sofía is an astonishing spot in the city that will captivate you with its unique charm.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Spain is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Madrid's best restaurants.

Don’t miss out on dining at Alhambra, a top-rated dining destination in Madrid. If you're in the mood to try something new, consider Restaurante Alabaster, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurante De María - Felíx Boix. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Madrid this evening.

After enjoying a fulfilling meal, continue your evening at Jazz Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, España Building offers a welcoming atmosphere for easing into the nightlife. Similarly, 1862 Dry Bar provides an excellent environment for a relaxed and enjoyable evening.

Relax and reminisce about your day in Spain and look forward to more memorable moments to come!

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Day 8

Day 8

  • Madrid
  • More

Drive 150 km, 2 hours 26 min

  • Alcázar of Toledo
  • Santa Iglesia Catedral Primada de Toledo
  • El Greco Museum
  • Monasterio de San Juan de los Reyes, Toledo
  • FLY TOLEDO
  • San Martin's Bridge
  • More

On day 8 of your road trip, you’ll start and end your day in Madrid, where you'll stay for 1 night more.

Enjoy the perfect balance of relaxation and exploration in Madrid today. One of the most well-known attractions included on the itinerary is Alcázar Of Toledo. This breathtaking castle will help you start your sightseeing on top. Then, take a leisurely stroll to Santa Iglesia Catedral Primada De Toledo and learn what makes this stunning church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the often recommended El Greco Museum. After exploring the museum, head to Monasterio De San Juan De Los Reyes, Toledo. This frequently visited monastery is a highlight in Madrid. Lastly, don’t forget to check out the notable San Martin's Bridge. Enjoy exploring this incredible monument at your own pace.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Madrid.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Madrid. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Areia, a top-rated dining destination in Madrid. If you're in the mood to try something new, consider La MaMá Restaurante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sacha Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Madrid this evening.

Relax and reminisce about your day in Spain and look forward to more memorable moments to come!

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Day 9

Day 9

  • Madrid
  • Santander
  • More

Drive 437 km, 5 hours 4 min

  • Parque Campo Grande
  • Plaza de Zorrilla
  • Cathedral of Valladolid
  • Plaza Mayor
  • Iglesia De San Benito
  • More

Experience an unparalleled adventure on day 9 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Valladolid. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Santander. You will spend 1 night here for some well-deserved relaxation.

Today's adventure in Madrid promises more breathtaking discoveries and enriching experiences! Begin at Parque Campo Grande. This eye-catching park is a highlight of any visit in the city. Then, enjoy Plaza De Zorrilla, another enchanting attraction that never fails to captivate visitors. Next, head over to Cathedral Of Valladolid, one of the city’s most intriguing attractions, known for its culturally significant features.

If you’re looking for more, spend time soaking in the atmosphere of Plaza Mayor. This majestic public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Iglesia De San Benito El Viejo, an often recommended church, and take a stroll around the area.

At the end of the day, you will drive to Santander, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Santander. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Restaurante Agua Salada, a popular restaurant in Santander. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Santander at Restaurante Matices Santander, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated La Enmienda Dieciocho. It’s yet another ideal choice to enhance your time in Santander tonight.

To truly maximize your evening out, consider visiting Little Bobby after dinner. This bar is known for offering some of the best drinks and vibes in the city.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Spain.

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Day 10

Day 10

  • Santander - Departure day
  • More
  • Plaza Pombo
  • More

Day 10 of your road trip in Spain is your departure day. This is your chance to catch a last glimpse of Santander before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Plaza De Pombo. This beloved public square is a popular place to see in the city.

On your last day in Spain, take time to indulge in shopping at Santander’s popular marketplace, El Corte Inglés. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Spain, drop by another restaurant for a last chance at a memorable dining experience in Santander.

You’ll then say farewell to Santander. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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