10-Day Spain Self-Drive Road Trip With Itinerary from Vitoria-Gasteiz traveling south to Santander, Valladolid, Madrid, and Calatayud

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Photo of Virgen blanca square at vitoria, spain.
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Explore the best of Spain on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Vitoria-Gasteiz, Santander, Villaescusa, Valladolid, Segovia, San Lorenzo de El Escorial, Madrid, Toledo, Calatayud, and Zaragoza.

This perfectly planned road trip itinerary takes you through some of the best places to see in Spain. You will spend 2 nights in Vitoria-Gasteiz, 1 night in Santander, 1 night in Valladolid, 4 nights in Madrid, and 1 night in Calatayud. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Vitoria-Gasteiz, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. El Retiro Park and Main Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Santiago Bernabéu Stadium, learn more about the unique Market Of San Miguel, and immerse yourself in the vibrant atmosphere of Museo Del Prado.

As you hit the open road and drive through Vitoria-Gasteiz, Santander, Villaescusa, Valladolid, Segovia, San Lorenzo de El Escorial, Madrid, Toledo, Calatayud, and Zaragoza, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Vitoria-Gasteiz - Arrival day
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  • La Florida
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Your road trip adventure in Spain begins as soon as you reach Vitoria-Gasteiz and pick up your car. You’ll stay here for 1 night and explore what to see in Vitoria-Gasteiz, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Vitoria-Gasteiz is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out La Florida, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Vitoria-Gasteiz. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Spain. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Vitoria-Gasteiz, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Mano lenta jatetxea, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Riojana Restaurante? It's another excellent option with a diverse menu. Consider reserving a table at Restaurante-Asador Matxete as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Vitoria-Gasteiz.

To truly maximize your evening out, consider visiting Soho Vitoria-cocktail Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Taberna Txustarra, another bar with an inviting ambiance. Similarly, Aldapa Taberna also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 10-day road trip in Spain!

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Day 2

Day 2

  • Vitoria-Gasteiz
  • Santander
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Drive 166 km, 2 hours 13 min

  • Santa Maria Cathedral
  • Artium Museum
  • Parque Salburua
  • Arriagako Donibane Parkea
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Your itinerary for day 2 of your road trip in Spain includes 3 stops and features some of the highlights of Vitoria-Gasteiz, Elorriaga, and Arriaga. At the end of the day, enjoy the comforts of a top-rated hotel in Santander, where you'll spend 1 night.

Make a stop at Cathedral Of Santa María De Vitoria. This up-and-coming church is a must-visit for travelers looking for a unique holiday experience. Make your way to Artium Museum located in Vitoria-Gasteiz for another exciting encounter.

Next, immerse yourself in the setting of Salburua. Its enchanting features will captivate you. After the nature reserve, continue your tour of the city with a visit to Arriagako Donibane Parkea. Visitors usually appreciate the enchanting features of this park.

When you’re done exploring for the day, you’ll drive to your hotel in Santander. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Santander's best restaurants.

Treat yourself to an extraordinary dining experience at Cadelo, a Bib Gourmand restaurant offering an incredible modern menu. Alternatively, if your taste buds call for something different, Umma is one of the best restaurants for modern cuisine in Santander. This Bib Gourmand-awardee earns consistently high praises from guests. We also recommend checking out the menu at Agua Salada. As a top-rated establishment with a Bib Gourmand status, it is an ideal choice for contemporary and traditional cuisine in the city.

Cap off your dinner by heading to Kings Pub, ideal for a leisurely evening with a drink in hand. Grog is another bar that offers an enjoyable setting. Similarly, Hygge Cocktail is also a popular place to go on a night out, perfect for relaxing and socializing.

Take some time to reflect on your day and savor another beautiful night in Spain.

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Day 3

Day 3

  • Santander
  • Valladolid
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Drive 273 km, 3 hours 16 min

  • Mercado del Este
  • Botin Centre
  • Palacio de la Magdalena
  • Cabarceno Natural Park
  • More

On day 3 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 2 destinations, including Santander and Villaescusa. When you’re not sightseeing, take time to relax at your chosen hotel in Valladolid, where you’ll be staying for 1 night.

Let Mercado Del Este set the tone for the day. Spend some time admiring this historic market before continuing your journey. Centro Botin is your next stop. This captivating art gallery is one of the best-rated sights in Santander.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Palacio De La Magdalena. This romantic palace is a sight to behold. To round off your sightseeing experience, visit Cabarceno Natural Park.

At the end of the day, you will drive to Valladolid, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Valladolid's most popular restaurants, and connect with friendly locals for a true cultural experience.

Get ready for an unforgettable culinary journey in Valladolid by reserving a table at Llantén. Renowned as a Bib Gourmand restaurant, it offers an exceptional traditional menu. For a different taste experience, head to Alquimia - Laboratorio, recognized for its delicious creative and modern dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Trigo, a local favorite known for its delightful modern cuisine in Valladolid. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for modern foodies seeking culinary excellence.

Explore the vibrant nightlife at Bar Panoramix after your meal, a hub for lively evenings and memorable moments. Or, head to Bar Esgueva for a great selection of flavorful drinks and a charming setting. Furthermore, Largo Adiós is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass to another unforgettable day in Spain!

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Day 4

Day 4

  • Valladolid
  • Madrid
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Drive 229 km, 3 hours 16 min

  • Aqueduct of Segovia
  • Segovia Cathedral
  • Alcázar of Segovia
  • Royal Basilica of San Lorenzo de El Escorial
  • More

Experience an unparalleled adventure on day 4 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Segovia and San Lorenzo de El Escorial. At the end of the day, you will retreat to the hotel of your choice in Madrid, where will spend 4 nights.

No visit to Valladolid is complete without Aqueduct Of Segovia. This iconic monument is one of the top attractions in the city. Proceed to Segovia Cathedral, another must-visit attraction.

As you wander through the inviting streets of Valladolid, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Alcázar Of Segovia. This astonishing castle is a traveler-favorite. Not far away, you’ll find Royal Monastery Of San Lorenzo De El Escorial, another key site on your sightseeing itinerary.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Madrid. Madrid offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Madrid. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a harmony of flavors at DiverXO in Madrid by securing a reservation in advance. Known for its 3-star Michelin status, DiverXO offers a delightful variety of dishes highlighting its delicious creative menu. If you're seeking an alternative culinary experience, be sure to explore Smoked Room, a highly recommended restaurant known for its enticing contemporary cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Paco Roncero, a highly acclaimed restaurant celebrated for its exceptional creative menu.

Continue the enjoyment post-dinner at Bar Yambala, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Baton Rouge Cocktail Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Cafe Madrid. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Head back to your accommodation in Madrid and get some rest to prepare for another magical day of your road trip in Spain.

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Day 5

Day 5

  • Madrid
  • More

Drive 161 km, 2 hours 44 min

  • Santa Iglesia Catedral Primada de Toledo
  • Alcázar of Toledo
  • Museo Nacional Centro de Arte Reina Sofía
  • Casa de Campo
  • More

On day 5 of your road trip, you'll get the chance to experience Toledo and Madrid. At the end of the day, you'll drive back to Madrid, where you still have 3 nights left to stay.

Start your day at Santa Iglesia Catedral Primada De Toledo. This symbolic church is a captivating place to see in Madrid. Then, wander over to Alcázar Of Toledo. If breathtaking sites excite you, this castle will be right up your alley. Nearby, you’ll also find Museo Nacional Centro De Arte Reina Sofía. This heritage-rich museum is a favorite among visitors.

Madrid offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Casa De Campo is an impressive spot in the city that will captivate you with its unique charm.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Madrid.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Madrid, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Alhambra, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Restaurante Alabaster? It's another excellent option with a diverse menu. Consider reserving a table at Restaurante De María - Felíx Boix as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Madrid.

Explore the vibrant nightlife at Jazz Bar after your meal, a hub for lively evenings and memorable moments. Or, head to España Building for a great selection of flavorful drinks and a charming setting. Furthermore, 1862 Dry Bar is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Madrid and look forward to another great day of your road trip in Spain!

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Day 6

Day 6

  • Madrid
  • More

Drive 3 km, 45 min

  • Market of San Miguel
  • Main Square
  • Thyssen-Bornemisza Museum
  • Museo del Prado
  • La Latina
  • More

On day 6 of your road trip, you will have an entire day to discover what to see in Madrid. You’ll stay in Madrid for 2 nights.

Whether you decide to explore Madrid on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Make sure to visit La Latina, a popular neighborhood in Madrid. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

Market Of San Miguel is perfect for a self-paced visit during the day. This photogenic food market is sure to impress. Next on your list is Main Square, another must-visit landmark and world-famous public square renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Madrid by sampling some local delicacies. When you’re ready for more sightseeing, head to Thyssen-bornemisza Museum. This photogenic museum is an essential place to visit for anyone looking for the full Madrid experience. We also recommend visiting Museo Del Prado, a timeless museum.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Madrid. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Areia, a top-rated dining destination in Madrid. If you're in the mood to try something new, consider La MaMá Restaurante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sacha Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Madrid this evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Spain.

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Day 7

Day 7

  • Madrid
  • More

Drive 14 km, 1 hour 10 min

  • Royal Palace of Madrid
  • Temple of Debod
  • plaza de España
  • Santiago Bernabéu Stadium
  • Malasaña
  • More

Day 7 offers an itinerary packed with the best things to see in Madrid. You’ll stay in Madrid for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t miss Malasaña today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Royal Palace Of Madrid brings Madrid's character to life. This history-steeped palace is a highlight of any visit in the city. Then, enjoy Temple Of Debod, another history-steeped attraction that never fails to captivate visitors. Next, head over to Plaza De España, one of the city’s most impressive attractions, known for its picture-perfect features.

If you’re looking for more, spend time soaking in the atmosphere of Santiago Bernabéu Stadium. This picture-perfect stadium is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Madrid's best restaurants.

Have a fantastic dining experience at Taberna Mozárabe, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Restaurante Lakasa offers an enticing alternative with its varied menu. Additionally, Lambuzo is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Madrid.

Head back to your accommodation in Madrid and get some rest to prepare for another magical day of your road trip in Spain.

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Day 8

Day 8

  • Madrid
  • Calatayud
  • More

Drive 235 km, 3 hours 6 min

  • Puerta de Alcalá
  • Great Pond of El Retiro
  • El Retiro Park
  • Crystal Palace
  • More

On day 8 of your road trip in Spain, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Madrid are on today's agenda. In the evening, you’ll end up in Calatayud, where you will stay for 1 night.

Catch Puerta De Alcalá before the crowds roll in. This romantic monument is sure to ignite your curiosity. Next, dive into the stunning features of Great Pond Of El Retiro, a must-visit lake in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to El Retiro Park, a world-famous park. For a change of scene, check out Crystal Palace, known for its romantic features.

When you’re done exploring for the day, you’ll drive to your hotel in Calatayud. Check in and relax before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Calatayud. Enjoy a relaxing evening as you savor delicious local cuisine.

Known for great service, it’s a fantastic choice for tonight in Calatayud.

Savor another day of unforgettable experiences in Spain!

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Day 9

Day 9

  • Calatayud
  • Vitoria-Gasteiz
  • More

Drive 348 km, 3 hours 48 min

  • Plaza de Nuestra Señora del Pilar
  • Sala de Exposiciones La Lonja
  • Parque de la Aljafería
  • More

Dive into day 9 of your remarkable road trip in Spain. Today you'll explore 1 destination, including Zaragoza. At the end of the day, you’ll unwind at one of the finest accommodations in Vitoria-Gasteiz, where you'll spend 1 night.

To truly experience Calatayud, make sure to drop by Basilica Of Our Lady Of The Pillar. This captivating church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Sala De Exposiciones La Lonja, one of the city’s best highlights.

Next, check out Parque De La Aljafería, one of the most underrated places to see in Calatayud. This castle is a favorite among locals and travelers alike.

At the end of the day, you will drive to Vitoria-Gasteiz, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Vitoria-Gasteiz is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Vitoria-Gasteiz.

Have a memorable dining experience in Vitoria-Gasteiz by booking a table at Zabala, a Bib Gourmand restaurant presenting an exceptional contemporary menu. Immerse yourself in the culinary delights of Bar Txiki, a popular restaurant in Vitoria-Gasteiz. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Relax and recharge in preparation for another adventurous day in Spain!

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Day 10

Day 10

  • Vitoria-Gasteiz - Departure day
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  • Plaza España
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Day 10 of your road trip in Spain is your departure day. This is your chance to catch a last glimpse of Vitoria-Gasteiz before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Nueva Square. This often recommended public square is a hotspot among locals.

Before you conclude your road trip in Spain, drop by another restaurant for a last chance at a memorable dining experience in Vitoria-Gasteiz.

If you're in the mood to try something new, consider Cafetería El Pregón, another top spot with a mouthwatering menu.

You’ll then say farewell to Vitoria-Gasteiz. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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