12-Day Spain Self-Drive Road Trip With Itinerary from Santiago De Compostela traveling east to Leon, Madrid, and Salamanca

1 / 61
Photo of beautiful view of Alameda Park of Santiago de Compostela.
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Escape the ordinary with this exciting 12-day road trip through Spain. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Spain. You will spend 3 nights in Santiago De Compostela, 2 nights in Leon, 4 nights in Madrid, and 2 nights in Salamanca. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Santiago De Compostela, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. El Retiro Park and Main Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Santiago De Compostela, Leon, Madrid, Toledo, Segovia, Zamarramala, Salamanca, Zamora, and Ponferrada, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Santiago De Compostela

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in
Pick-up: 10:00
Drop-off: 10:00

Personalize your itinerary

Customize tours under each day and destination

Day 1

Day 1

  • Santiago de Compostela - Arrival day
  • More
  • Parque da Alameda (Santiago de Compostela)
  • More

Your road trip adventure in Spain begins as soon as you reach Santiago De Compostela and pick up your car. You’ll stay here for 2 nights and explore what to see in Santiago De Compostela, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Santiago De Compostela is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Santiago De Compostela. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Spain. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Santiago De Compostela, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 12-day road trip in Spain!

Read more
Day 2

Day 2

  • Santiago de Compostela
  • More

Drive 1 km, 23 min

  • Praza de Galicia
  • Pazo of Fonseca
  • Museum of Pilgrimage
  • Praza da Quintana de Vivos
  • Cathedral of Santiago de Compostela
  • Monasterio de San Martín Pinario
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

Santiago De Compostela is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Santiago De Compostela.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Spain.

Read more
Day 3

Day 3

  • Santiago de Compostela
  • León
  • More

Drive 317 km, 3 hours 35 min

  • Basilica of San Isidoro
  • Catedral de León
  • Museo Sierra Pambley
  • More

On day 3 of your road trip in Spain, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Leon are on today's agenda. In the evening, you’ll end up in Leon, where you will stay for 2 nights.

At the end of the day, you will drive to Leon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Leon, it's often a good idea to reserve a table in advance.

Relax and look forward to more memorable moments to come!

Read more
Day 4

Day 4

  • León
  • More

Drive 1 km, 19 min

  • Plaza del Grano, León
  • Conde Luna Palace
  • Casa de los Botines
  • More

Day 4 offers an itinerary packed with the best things to see in Santiago De Compostela. You’ll stay in Leon for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Leon's best restaurants.

Raise your glass and celebrate another amazing day of your road trip in Spain!

Read more
Day 5

Day 5

  • León
  • Madrid
  • More

Drive 344 km, 4 hours 8 min

  • plaza de España
  • El Retiro Park
  • Puerta de Alcalá
  • Statue of the Bear and the Strawberry Tree
  • More

On day 5 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 1 destination, including Madrid. When you’re not sightseeing, take time to relax at your chosen hotel in Madrid, where you’ll be staying for 4 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Madrid. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Madrid's best restaurants.

Raise your glass and celebrate another amazing day of your road trip in Spain!

Read more
Day 6

Day 6

  • Madrid
  • More

Drive 6 km, 1 hour 20 min

  • Temple of Debod
  • Royal Palace of Madrid
  • Market of San Miguel
  • Main Square
  • Thyssen-Bornemisza Museum
  • Museo del Prado
  • More

You have 3 nights left in Madrid. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Madrid. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Head back to your accommodation in Madrid and get some rest to prepare for another magical day of your road trip in Spain.

Read more
Day 7

Day 7

  • Madrid
  • More

Drive 151 km, 2 hours 52 min

  • San Martin's Bridge
  • Santa Iglesia Catedral Primada de Toledo
  • Alcázar of Toledo
  • Army Museum
  • Puerta de Bisagra
  • Monasterio de San Juan de los Reyes, Toledo
  • More

On day 7 of your road trip, you’ll start and end your day in Madrid, where you have 2 nights left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Madrid.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Madrid. Enjoy a relaxing evening as you savor delicious local cuisine.

Celebrate another amazing day of your road trip adventure in Spain!

Read more
Day 8

Day 8

  • Madrid
  • More

Drive 189 km, 3 hours 9 min

  • Aqueduct of Segovia
  • Plaza Mayor
  • Segovia Cathedral
  • Alcázar of Segovia
  • Royal Museum of the Mint of Segovia
  • Mirador de la Pradera de San Marcos
  • More

Greet day 8 of your road trip in Spain with a smile and start your day with a hearty breakfast. You have 1 night to stay in Madrid, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Segovia and Zamarramala.

When you’re done exploring for the day, you’ll return to Madrid and your accommodation.

Madrid is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Madrid.

Relax and look forward to more memorable moments to come!

Read more
Day 9

Day 9

  • Madrid
  • Salamanca
  • More

Drive 214 km, 2 hours 32 min

  • Convento de Sant Esteban
  • Calisto and Melibea Vegetable Garden
  • Casa Lis
  • Salamanca Cathedral
  • Casa de las Conchas
  • La Clerecía
  • More

Experience an unparalleled adventure on day 9 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Salamanca. At the end of the day, you will retreat to the hotel of your choice in Salamanca, where will spend 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Salamanca. Salamanca offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Salamanca. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Head back to your accommodation in Salamanca and get some rest to prepare for another magical day of your road trip in Spain.

Read more
Day 10

Day 10

  • Salamanca
  • More

Drive 9 km, 1 hour 12 min

  • Würzburg Park
  • Museum of Commerce
  • Casino de Salamanca
  • Plaza Mayor de Salamanca
  • Monterrey's palace
  • Roman bridge of Salamanca
  • More

You’ll stay in Salamanca for 1 night.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Salamanca. Enjoy a relaxing evening as you savor delicious local cuisine.

Get a good night's sleep and look forward to another great day on the road in Spain!

Read more
Day 11

Day 11

  • Salamanca
  • Santiago de Compostela
  • More

Drive 478 km, 5 hours 17 min

  • Zamora Castle
  • Cathedral of Zamora
  • Basílica Nuestra Señora de la Encina
  • Museo de la Radio
  • Museo de El Bierzo
  • More

Dive into day 11 of your remarkable road trip in Spain. Today you'll explore 2 destinations, including Zamora and Ponferrada. At the end of the day, you’ll unwind at one of the finest accommodations in Santiago De Compostela, where you'll spend 1 night.

At the end of the day, you will drive to Santiago De Compostela, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Santiago De Compostela. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor another day of unforgettable experiences in Spain!

Read more
Day 12

Day 12

  • Santiago de Compostela - Departure day
  • More
  • Parque de San Domingos de Bonaval
  • More

Day 12 of your road trip in Spain is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Browse boutiques to find unique and stylish fashion pieces.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Spain

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.