13-Day Spain Self-Drive Road Trip With Itinerary from Santiago De Compostela traveling south to Ponferrada, Arévalo, Madrid, Trujillo, Seville, Plasencia, and Leon

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Escape the ordinary with this exciting 13-day road trip through Spain. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Spain. You will spend 2 nights in Santiago De Compostela, 1 night in Ponferrada, 1 night in Arévalo, 3 nights in Madrid, 1 night in Trujillo, 2 nights in Seville, 1 night in Plasencia, and 1 night in Leon. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Spain. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Santiago De Compostela, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Spain on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Spain. El Retiro Park and Main Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Santiago De Compostela, Ponferrada, Valladolid, Arévalo, Segovia, Madrid, Trujillo, Merida, Seville, Almendralejo, Plasencia, Salamanca, Leon, and Lugo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Spain. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Spain.

Throughout your road trip in Spain, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Spain.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Spain fill up quickly, so book your spot early. Select a date and start planning your road trip in Spain today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Santiago de Compostela - Arrival day
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  • Praza de Galicia
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Say hello to Santiago De Compostela! Your exciting road trip through Spain is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Santiago De Compostela for 1 night before you continue your adventure!

Santiago De Compostela is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Santiago De Compostela. Check-in typically starts around 2 to 4 PM at hotels in Spain. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Santiago De Compostela, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 13-day road trip in Spain!

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Day 2

Day 2

  • Santiago de Compostela
  • Ponferrada
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Drive 217 km, 3 hours 1 min

  • Museo del Pueblo Gallego
  • City of Culture of Galicia
  • Cathedral of Santiago de Compostela
  • Praza da Quintana de Vivos
  • More

On day 2 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 2 destinations, including Santiago De Compostela and O Cruceiro de Sar. When you’re not sightseeing, take time to relax at your chosen hotel in Ponferrada, where you’ll be staying for 1 night.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Santiago De Compostela.

At the end of the day, you will drive to Ponferrada, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Ponferrada is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Ponferrada.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Spain.

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Day 3

Day 3

  • Ponferrada
  • Arévalo
  • More

Drive 323 km, 3 hours 36 min

  • Parque Campo Grande
  • Plaza de Zorrilla
  • Plaza Mayor
  • Parque y playa de las Moreras
  • More

Your itinerary for day 3 of your road trip in Spain includes 1 stop and features some of the highlights of Valladolid. At the end of the day, enjoy the comforts of a top-rated hotel in Arévalo, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Arévalo. Arévalo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Arévalo's best restaurants.

As the sun sets, rest up and recharge for the next leg of your road trip in Spain.

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Day 4

Day 4

  • Arévalo
  • Madrid
  • More

Drive 154 km, 2 hours 23 min

  • Alcázar of Segovia
  • Segovia Cathedral
  • Plaza Mayor
  • Casa de los Picos
  • Aqueduct of Segovia
  • More

Experience an unparalleled adventure on day 4 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Segovia. At the end of the day, you will retreat to the hotel of your choice in Madrid, where will spend 3 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Madrid. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Madrid. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Take some time to reflect on your day and savor another beautiful night in Spain.

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Day 5

Day 5

  • Madrid
  • More

Drive 20 km, 1 hour 23 min

  • Museo Nacional Centro de Arte Reina Sofía
  • Temple of Debod
  • plaza de España
  • Santiago Bernabéu Stadium
  • Malasaña
  • More

Day 5 offers an itinerary packed with the best things to see in Santiago De Compostela. You’ll stay in Madrid for 2 nights more, offering you enough time to explore at a relaxed pace.

One of the most iconic spots you can visit today is Malasaña. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Madrid.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Madrid's most popular restaurants, and connect with friendly locals for a true cultural experience.

Relax and recharge in preparation for another adventurous day in Spain!

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Day 6

Day 6

  • Madrid
  • More

Drive 5 km, 53 min

  • Crystal Palace
  • El Retiro Park
  • Puerta de Alcalá
  • Museo del Prado
  • Gran Vía
  • More

Set aside time today to explore Gran Vía, a standout street that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

Madrid is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Madrid.

Savor another day of unforgettable experiences in Spain!

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Day 7

Day 7

  • Madrid
  • Trujillo
  • More

Drive 259 km, 3 hours 6 min

  • Main Square
  • Market of San Miguel
  • Royal Palace of Madrid
  • Casa de Campo
  • More

On day 7 of your road trip in Spain, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Madrid are on today's agenda. In the evening, you’ll end up in Trujillo, where you will stay for 1 night.

At the end of the day, you will drive to Trujillo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Trujillo's most popular restaurants, and connect with friendly locals for a true cultural experience.

Relax and recharge in preparation for another adventurous day in Spain!

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Day 8

Day 8

  • Trujillo
  • Seville
  • More

Drive 280 km, 3 hours 18 min

  • López de Ayala Park
  • Roman Theatre of Emerita Augusta
  • National Museum of Roman Art
  • Pórtico del Foro Municipal de Augusta Emérita
  • Temple of Diana
  • More

Dive into day 8 of your remarkable road trip in Spain. Today you'll explore 1 destination, including Merida. At the end of the day, you’ll unwind at one of the finest accommodations in Seville, where you'll spend 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Seville. Seville offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Seville, it's often a good idea to reserve a table in advance.

Head back to your accommodation in Seville and get some rest to prepare for another magical day of your road trip in Spain.

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Day 9

Day 9

  • Seville
  • More

Drive 8 km, 56 min

  • Metropol Parasol
  • Royal Alcázar of Seville
  • Plaza de España
  • Santa Cruz
  • Calle de las Sierpes
  • More

You have 1 night left in Seville. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Spain. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Seville. Enjoy a relaxing evening as you savor delicious local cuisine.

Say good night to Seville and look forward to another great day of your road trip in Spain!

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Day 10

Day 10

  • Seville
  • Plasencia
  • More

Drive 349 km, 3 hours 44 min

  • La Giralda
  • Catedral de Sevilla
  • Piedad Park
  • More

On day 10 of your exciting self-drive vacation in Spain, you’ll soak in the magnificence of 2 destinations, including Seville and Almendralejo. When you’re not sightseeing, take time to relax at your chosen hotel in Plasencia, where you’ll be staying for 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Plasencia. Check in and relax before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Plasencia. Enjoy a relaxing evening as you savor delicious local cuisine.

Get a good night's sleep and look forward to another great day on the road in Spain!

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Day 11

Day 11

  • Plasencia
  • León
  • More

Drive 338 km, 3 hours 45 min

  • Monumento al Lazarillo de Tormes
  • Centro Documental de la Memoria Histórica
  • Casa Lis
  • More

Your itinerary for day 11 of your road trip in Spain includes 1 stop and features some of the highlights of Salamanca. At the end of the day, enjoy the comforts of a top-rated hotel in Leon, where you'll spend 1 night.

At the end of the day, you will drive to Leon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Leon is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Leon.

Raise your glass and celebrate another amazing day of your road trip in Spain!

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Day 12

Day 12

  • León
  • Santiago de Compostela
  • More

Drive 326 km, 3 hours 43 min

  • Catedral de León
  • Casa de los Botines
  • Miño Park (Riverwalk)
  • More

Experience an unparalleled adventure on day 12 of your road trip in Spain. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Leon and Lugo. At the end of the day, you will retreat to the hotel of your choice in Santiago De Compostela, where will spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Santiago De Compostela. Santiago De Compostela offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Santiago De Compostela's best restaurants.

Raise your glass to another unforgettable day in Spain!

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Day 13

Day 13

  • Santiago de Compostela - Departure day
  • More
  • Parque da Alameda (Santiago de Compostela)
  • More

Day 13 of your road trip in Spain is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Discover boutiques offering an array of stylish fashion choices.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Spain!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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