Luxury 6-Day Czech Republic Road Trip from Prague traveling south to Ceske Budejovice and Brno

Your luxury holiday in Czech Republic begins as soon as you reach the city of Prague, where you'll be staying for 2 nights. There, you’ll pick up the luxury rental vehicle of your choice and hit the roads!

When you’re ready for some sightseeing, make your way to Powder Tower. This much-appreciated museum is rated 4.6 out of 5 stars in 41,106 reviews. Each year, 27,072 people visit this site to admire its unique features.

Tonight, you will be treated to a stay at one of the best luxury hotels in Prague. We have picked out three of the most exclusive luxury lodging and hotel options for you to choose from.

Exploring new destinations can leave you craving great food and drinks. Satisfy your cravings and unwind by visiting the finest restaurants and bars in Prague.

Let the evening flow smoothly from dinner to drinks at BeerGeek Bar, a top-rated bar in the area. For other recommendations, Hemingway Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Anonymous Bar offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 6-day luxury vacation in Czech Republic and look forward to more fantastic days to come!

Day 2 of your luxury road trip in the Czech Republic begins and concludes in the city of Prague. Set out by car to explore incredible attractions in the nearby area. After a day filled with sightseeing, you'll return to Prague, where you still have 1 night nights remaining.

Seize the day by visiting some of the best attractions in the area, like Prague Zoo. This extraordinary zoo has an average rating of 4.8 out of 5 stars from 56,551 visitors. Each year, around 1,445,126 people visit this remarkable site to admire its features and learn more about it.

Next, make your way to Letná Park. This park is rated an average of 4.7 out of 5 stars in 25,680 reviews.

While in Prague, we also recommend a visit to Vyšehrad. Hosting around 45,878 visitors every year, Vyšehrad is one of the best places to visit. This fortress has been rated an average of 4.8 out of 5 stars in 45,689 reviews.

If you’re keen to explore even more, then consider a visit to Dancing House. With an average rating of 4.3 out of 5 stars by 53,539 travelers, this office building is a highly recommended stop on your sightseeing around Prague.

Make your way to Petřín Lookout Tower, perhaps the most famous observation tower in Prague. This attraction welcomes around 234,200 visitors annually and is rated an average of 4.5 out of 5 stars in 28,408 reviews.

After a long day of discovering the unique quirks of Czech Republic, it’s an excellent idea to sit down for a lovely meal or enjoy a refreshing drink. We’ve gathered the most recommended dining and drinking spots in Prague so you can check out the menus and make advance reservations.

Continue your lively evening at Black Angel's Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. DÉJÁVU Music Club Prague is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, NIGHTMARE Prague Horror Bar ensures a night out tailored to your taste.

Raise a toast to another amazing day of your luxury holiday in Prague, Czech Republic and seize the opportunity to celebrate.

On day 3 of your luxury holiday in Czech Republic, your road trip route will take you exploring the best of Prague. With a day brimming with amazing attractions ahead, fuel up with a hearty breakfast to savor every moment of your luxury vacation in Czech Republic.

Embrace the thrill of the open road as you wave goodbye to Prague and set your GPS to Ceske Budejovice. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 38 min. Upon reaching Ceske Budejovice, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

An excellent attraction to start your day with is Prague Astronomical Clock. This astronomical clock is rated an average of 4.7 out of 5 stars in 61,492 reviews.

Continue your journey at Old Town Square. This square is rated 4.8 out of 5 stars by 103,139 travelers from near and far.

Prague is also the home of Prague Castle. This castle has an average rating of 4.7 out of 5 stars from 167,293 visitors. Each year, around 512,800 travelers visit this top sight, and today is your chance to do the same.

You can continue your self-guided sightseeing tour at St. Vitus Cathedral. Rated 4.8 out of 5 stars by 80,048 visitors, a visit to this top sight is time well spent.

Lastly, don't miss out on Národní Muzeum (National Museum, Prague). With an average rating of 4.5 out of 5 stars from 34,095 reviews, it’s hard to refuse the opportunity to see this national museum.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Ceske Budejovice.

After a day filled with travel and exploration, we recommend you treat yourself to a meal or a drink at the finest restaurants and bars in Ceske Budejovice. Savor the local cuisine and relax as you recount the day's experiences.

Let the evening flow smoothly from dinner to drinks at The Dark, a top-rated bar in the area. For other recommendations, Cafe Hostel provides a perfect setting for rounding out your night with style and great drinks. Likewise, Singer Pub offers a memorable night with diverse drink options and excellent service.

Raise a toast to another amazing day of your luxury holiday in Prague, Czech Republic and seize the opportunity to celebrate.

Wake up to day 4 of your luxury road trip holiday in Czech Republic! Today, you will get the opportunity to visit multiple fantastic bucket-list destinations in the country as you head towards the city of Brno, where you'll be staying for 1 night. The day's itinerary unfolds with a diverse array of experiences in Hluboká nad Vltavou and Český Krumlov.

When you’re ready to jump back into the car and say goodbye to Český Krumlov, you’ll hit the road in the direction of Hluboká nad Vltavou. This drive usually takes around 37 min. When you arrive, enjoy some sightseeing.

Make Ohrada Zoo your first stop of the day. Previous visitors have rated this zoo an average of 4.6 out of 5 stars in 12,244 reviews. More than 201,500 people visit this place of interest every year.

Next up, make a stop at The State Chateau of Hluboká. With an average rating of 4.8 out of 5 stars by 23,761 visitors, it's easy to understand why so many people visit this point of interest every year.

Fasten your seatbelt and make your way to your next stop. Český Krumlov, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Ceske Budejovice to Český Krumlov may take around 31 min without traffic disruptions. Upon arrival in Český Krumlov, we highly recommend checking out some of the top attractions.

Kick off the day at Český Krumlov Castle, a top pick for today’s sightseeing. Attracting approximately 196,400 visits every year, this attraction is a must-see. This castle is rated an average of 4.8 out of 5 stars in 24,749 reviews.

Today is also your chance to visit The Castle Garden. The Castle Garden is a park with an average rating of 4.7 out of 5 stars from 5,448 reviews.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Brno.

In Brno, delicious dining experiences are never far from reach. Take your pick and consider whether you need to book a table in advance.

Cap off your dinner by heading to Bar Naproti, ideal for a leisurely evening with a drink in hand. Super Panda Circus is another bar that offers an enjoyable setting. Similarly, Výčep Na Stojáka is also a popular place to go on a night out, perfect for relaxing and socializing.

Reminisce about your day, look through photos, and prepare for another great day to come! Your luxury holiday in Czech Republic has plenty more in store for you.

Wake up to day 5 of your luxury holiday in Czech Republic! Remember to have a hearty breakfast because today will be filled with memorable adventures in Lednice and Mikulov. With a flexible itinerary, you're free to adapt and explore additional attractions or enjoy spontaneous discoveries.

As you’ve unraveled the marvels of Mikulov, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Lednice may take around 17 min. Upon your arrival in Lednice, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Kick off the day at Lednice Castle, a top pick for today’s sightseeing. Attracting approximately 256,000 visits every year, this attraction is a must-see. This château is rated an average of 4.8 out of 5 stars in 21,686 reviews.

Today is also your chance to visit Minaret. Minaret is a park with an average rating of 4.7 out of 5 stars from 5,867 reviews.

Lednice–Valtice Cultural Landscape is another top attraction we highly recommend you visit today. This park is rated an average of 4.8 out of 5 stars by 24,450 visitors.

After soaking in Brno’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Mikulov. Expect your car journey to take a minimum of 47 min. When you arrive in Mikulov, it's time to take a break from the road.

Take the opportunity to see Pálava Protected Landscape Area. This attraction has an average rating of 4.8 out of 5 stars from 11,934 visitors.

Relax and unwind in style as you spend the night at one of the top luxury hotels in in Prague.

After exploring the unique sights of Czech Republic, savor a delicious meal or get refreshed with a drink. We’ve gathered the most recommended restaurants and bars in the city of Prague for you so you can browse their menus in advance and make a reservation.

As a top-rated it is an ideal choice in the city.

Unwind after your meal by stepping into Brothers Bar & Cafe. This venue is celebrated for its extensive drink selections and cozy vibes.

Reminisce about your day, look through photos, and prepare for another great day to come! Your stress-free luxury holiday in Czech Republic has plenty more in store for you.

Today is the last day of your 6-day luxury holiday in Czech Republic and it’s soon time to start your journey home. This is your chance to get one last glimpse of Prague before saying goodbye.

On your last day in Czech Republic, take time to indulge in shopping at Prague’s popular marketplace. Thanks to your accommodation’s strategic location, the city’s bustling commercial district is only a stone’s throw away, giving you ample time to leisurely explore the area, filled with local shops.

Take time to find the perfect present, reminding you of the charms of Czech Republic. Each store here is brimming with unique finds. These souvenirs will help you treasure your memories of Czech Republic forever.

Treat yourself to a final feast. Savor the unique flavors of Prague one last time before you head to the airport.

Savor the flavors at Restaurace Malostranská beseda, a top pick for dinner tonight. Alternatively, U Parlamentu beckons with its unique menu offerings.

You will then say farewell to Prague and begin your journey home. We wish you safe travels and a warm welcome home, with unforgettable memories and incredible photos from your luxury holiday in Czech Republic in your luggage!