6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka and Ioannina

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Photo of Saint Paul cathedral in Thessaloniki, Greece.
Photo of the White Tower in Thessaloniki, Greece.
Photo of Aristotelous Square at Thessaloniki city, Panoramic view.
Photo of Aristotelous square, the heart of Thessaloniki city, Greece.
Photo of beautiful Rotonda in Thessaloniki on a hot sunny summer day.
Photo of Agia Anna monastery guesthouses in Mount Athos, Thessaloniki.
Photo of aerial view of Thessaloniki alongisde an old fortification, Greece.
Photo of a narrow street in the old town of Thessaloniki, Greece.
Photo of aerial panoramic view of the main symbol of Thessaloniki city.
Photo of Byzantine fortress situated on the north-eastern corner of the acropolis of Thessaloniki in Greece.
Photo of tourist enjoys the view of Galerius Arch in Thessaloniki city in Greece.
Archaeoiogical Museum of Thessaloniki,Thessaloniki.
Aristotelous Square,Thessaloniki
View of the pier of Neoi Epivates suburb of Thessaloniki, Greece.
photo of panoramic aerial view of the city of Kalabaka near the famous monasteries on the tops of stone pillars in Meteora. The concept of tourist accommodation and real estate in Greece.
photo of beautiful landscape of monasteries and rocks of Meteora , Greece.
photo of The Great Monastery of Varlaam on the high rock in Meteora, Meteora monasteries, Greece Kalambaka. UNESCO World Heritage.
photo of sunset over monastery of Rousanou and Monastery of St. Nicholas Anapavsa in famous greek tourist destination Meteora in Greece on sunset with sun rays and lens flare.
photo of Holy Monastery of Saint Nicholas Anapafsas at Meteora, Trikala region, Greece, UNESCO World Heritage Site.
photo of Kalabaka or Kalambaka and Kalampaka city center. It is a town and municipality in the Trikala region in Greece.
photo of a church with a tall elegant bell tower on a hill in front of huge rocky mountains above a town, Kalambaka, Meteora, Greece.
photo of sunny summer day among the rocks of Kalambaka. Vineyard belonging to the rock monasteries of Meteora, Greece.
photo of The Assumption of Virgin Mary byzantine church of the 11th century, Kalambaka, Greece.
photo of City Kastraki (Kalambaka) with rocky mountains of Meteora, the landmark of six monasteries in Thessaly, Greece.
photo of The monastery Meteora, rocky monasteries complex in Greece near Kalabaka city. Holy Monastery of the Great Meteoron.
photo of Holy Trinity Monastery (Agia Trias) and Kalabaka town at night in Greece.
photo of Panoramic view of the Assumption of Virgin Mary byzantine church in Meteora, Kalambaka town in Greece, on a sunny summer day.
Photo of Plakidas Bridge in Ioannina in Greece by DanaTentis
Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
Photo of Ioannina city and the lake Pamvotis located in Epirus, Greece.
Photo of Loannina lake in autumn season with platanus trees reflecter in the water, in greece
Photo of aerial view of Ioannina city in Greece.
Photo of the lake Pamvotis. Ioannina city, Greece.
Photo of Ioannina city old tranditional pedestrian street called Soutsou in greece.
Photo of autumn colors in Ioannina city ,Epirus, Greece.
Photo of famous ruins of Ali Pasha's palace and the Tower of Bohemond in the old byzantine castle of Ioannina, Greece.
Photo of aerial view of Ioannina city in Greece.
Photo of panoramic aerial view of the town and the Pamvotis lake, Ioannina in Greece.
Fethiye Mosque with the Tomb of Ali Pasha in the foreground, Ioannina, Greece
EPIRUS, GREECE. Politsa (or "Politsas") bridge over Arachthos river, Katsanochoria region, North Tzoumerka municipality, Ioannina prefecture.
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Explore the best of Greece on a 6-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Thessaloniki, Kastraki, Kalambaka, Ioannina, Anilio, and Metsovo. This road trip itinerary in Greece seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, and 1 night in Ioannina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Ioannina Castle.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Ioannina, Anilio, and Metsovo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
The Umbrellas by ZongolopoulosArchaeological Museum of ThessalonikiWhite Tower of ThessalonikiAgias Sofias SquareAristotelous SquareTsimiski Street
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamMain Observation Deck of MeteoraNatural History Museum of Meteora and Mushroom MuseumGreek Education Museum
Silversmithing MuseumIch Kale Acropolis of IoanninaMuseum "Arslan Pasha"Ioannina CastleLitharitsia parkThe Clock Tower of Ioannina
Καταρράκτης ΑνήλιουAveroff Art GalleryMetsovo squareMetsovo Folk Art Museum (Tossizza Mansion)Αβερώφειος Κήπος
Arch of Galerius

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Kitchen Bar, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of The Greek, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Phanós, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the excitement of the evening going by visiting a bar or two. Beetle Bar is an excellent place to start. You could also check out Vogatsikou 3, offering a different kind of charm. A last recommendation for the day is Souel. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise a toast to the start of your 6-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
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Drive 6 km, 1 hour 4 min

  • The Umbrellas by Zongolopoulos
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Agias Sofias Square
  • Aristotelous Square
  • Tsimiski Street
  • More

On day 2 of your road trip, you will have an entire day to explore Thessaloniki. You’ll stay in Thessaloniki for 1 night and discover all the best things to see and do in the area.

Tsimiski Street is one of the highlights of today. Take your time exploring this iconic street in Thessaloniki, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Immerse yourself in Thessaloniki’s rich culture with today's sightseeing itinerary. Start your journey at The Umbrellas Sculpture By Zogolopoulos. This enchanting art installation is sure to ignite your curiosity. Next, dive into the eye-catching features of Archaeological Museum Of Thessaloniki, a must-visit museum in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to White Tower Of Thessaloniki, a spectacular monument. For a change of scene, check out Agias Sofias Square, known for its photogenic features. We also recommend visiting Aristotelous Square. This public square is a must for anyone looking to experience the city to the fullest.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely meal at Mamalouka, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Clochard is another top choice with a popular menu. You could also check for a table at Sofi's House Restaurant. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Thessaloniki tonight.

Let the evening flow smoothly from dinner to drinks at Castra- All Day Terrace Bar, a top-rated bar in the area. For other recommendations, Barbaben - Bar/ba/ben provides a perfect setting for rounding out your night with style and great drinks. Likewise, Apallou offers a memorable night with diverse drink options and excellent service.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 3

Day 3

  • Thessaloniki
  • Meteora
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Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

Embark on another extraordinary experience on day 3 of your road trip in Greece. Today, you will make 2 stops and experience some of the highlights of Kastraki and Kalambaka. At the end of the day, you will enjoy the comforts of a top-rated hotel in Kalambaka, which will be your home away from home for 1 night.

Start by visiting Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, a prime spot to begin your journey. This historic monastery is sure to impress. Next on your list is Monastery Of Varlaam, another must-visit landmark and underrated monastery renowned for its respected features.

While exploring and sightseeing, take time to savor the culture of Thessaloniki by sampling some local delicacies. When you’re ready for more sightseeing, head to Main Observation Deck Of Meteora. This standout observation deck is an essential place to visit for anyone looking for the full Thessaloniki experience. We also recommend visiting Natural History Museum Of Meteora And Mushroom Museum, a locally appreciated museum. Nearby, you'll also find Greek Education Museum, ready to add charm to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Kalambaka. Check in and spend some time relaxing before you head out to tour the town.

As dinnertime approaches, it's time to head out for a bite to eat in Kalambaka. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

With its reputation for pleasing customers, it’s a fantastic choice for tonight in Kalambaka.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 4

Day 4

  • Meteora
  • Ioannina
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Drive 106 km, 2 hours 26 min

  • Silversmithing Museum
  • Ich Kale Acropolis of Ioannina
  • Museum "Arslan Pasha"
  • Ioannina Castle
  • Litharitsia park
  • The Clock Tower of Ioannina
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 1 destination, Ioannina. When you’re not sightseeing, take time to relax at your selected hotel in Ioannina, where you’ll be staying for 1 night.

Today's adventure in Kalambaka promises more breathtaking discoveries and enriching experiences! Begin at Silversmithing Museum Of Ioannina. This visually striking museum is a highlight of any visit in the city. Then, enjoy Ic Kale Acropolis Of Ioannina, another breathtaking attraction that never fails to captivate visitors.

If you’re looking for more, spend time soaking in the atmosphere of Ioannina Castle. This romantic castle is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Litharitsia Park, a locally appreciated park, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out The Clock Tower Of Ioannina before you head back to your hotel.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Ioannina's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at To Dodeka Cafe Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Mustagogia offers an enticing alternative with its varied menu. Additionally, Accademia Del Panino is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Ioannina.

After your meal, keep the night alive at a bar like ⚜ V E D E M A ⚜, known for its lively atmosphere. Hogwarts Tales And Spirits is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Chevalier offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in Greece!

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Day 5

Day 5

  • Ioannina
  • Thessaloniki
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Drive 270 km, 3 hours 53 min

  • Καταρράκτης Ανήλιου
  • Averoff Art Gallery
  • Metsovo square
  • Metsovo Folk Art Museum (Tossizza Mansion)
  • Αβερώφειος Κήπος
  • More

On day 5 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Anilio and Metsovo. In the evening, you’ll end up in Thessaloniki, where you will stay for 1 night.

Get ready to discover some of the most iconic wonders in Ioannina, including a waterfall, an art gallery, a public square, a museum, a park and much more! Start your day at Katarraktis Anilioy. This stunning waterfall is a worthwhile place to see in Ioannina. Then, wander over to Averoff Art Gallery. If instagrammable sites excite you, this art gallery will be right up your alley. Nearby, you’ll also find Metsovo Square. This stunning public square is a favorite among visitors.

Ioannina offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Metsovo Folk Art Museum (tossizza Mansion) is a worthwhile spot in the village that will captivate you with its unique charm. When you’re done at the museum, don’t forget to check out the mesmerizing Averofeios Kipos. Take a moment to appreciate the fascinating details of this up-and-coming park.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Enoches Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try O Loytros? It's another excellent option with a diverse menu. Consider reserving a table at rOOTS as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Thessaloniki.

After enjoying a fulfilling meal, continue your evening at Peiratis Cafe-bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, In Rock Cafe Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Tribeca provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 6

Day 6

  • Thessaloniki - Departure day
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  • Arch of Galerius
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Day 6 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Arch Of Galerius And Rotunda, a photogenic monument before you head out.

Maximize your last day in Greece and go on a shopping spree in Thessaloniki’s shopping center, the lively Modiano Market. Browse for souvenirs to remind you of your wonderful journey in Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

If you're in the mood to try something new, consider Agora Ouzeri, another top spot with a mouthwatering menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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