7-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome and Florence
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Experience the freedom of the open road in Italy as you embark on an unforgettable 7-day road trip! This experience caters to every traveler, featuring destinations like Pescara, Rome, Florence, Pisa, and Santa Maria degli Angeli.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Pescara, 2 nights in Rome, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Pescara, Rome, Florence, Pisa, and Santa Maria degli Angeli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Pescara - Arrival day
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- Nature Reserve Pineta Dannunziana
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Welcome to Pescara, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Pescara's charm before embarking on the next leg of your journey.
Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Nature Reserve Pineta Dannunziana, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Pescara. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.
Treat yourself to a delightful dinner at Taverna 58, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Carlo Ferraioli? It's another excellent option with a diverse menu. Consider reserving a table at Sesamo Nero as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Pescara.
Continue your evening by exploring the vibrant nightlife scene at Posa Caffè Pescara, a prime destination for a thrilling night out. Also, don’t forget to check out Bar Mixer, a bar that offers unique local touches. Likewise, Temple Bar Irish Pub provides an excellent alternative for a fun evening.
Raise a toast to the start of your 7-day road trip in Italy!
Day 2
- Pescara
- Rome
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Drive 214 km, 3 hours 27 min
- Colosseum
- Roman Forum
- Pantheon
- Spanish Steps
- Piazza di Spagna
- Trevi Fountain
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Dive into day 2 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 2 nights.
Get ready for a day filled with fun adventures, scenic views, and picturesque spots in the charming city of Pescara. Your adventure starts at Colosseum, a world-famous local hot spot. Another notable attraction to explore is Roman Forum. This world-famous archeological site is known for its awe-inspiring appeal.
After soaking in the highlights of these sights, take some time to wander Pescara's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Pantheon. This heritage-rich monument offers a fascinating experience that many visitors find memorable. Spanish Steps is also worth visiting, along with Piazza Di Spagna. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Trevi Fountain. This globally renowned monument provides a fitting finale to your sightseeing.
At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a wonderful meal at La Bottega Roma, a top-rated dining spot in Rome. If you're in the mood for something new, try Pasta In Corso, another premier location with a delectable menu. You might also want to book a table at Trattoria Vecchia Roma. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.
Continue your lively evening at La Botticella Of Poggi Giovanni, a perfect place for winding down or revving up the night, depending on which mood you’re in. Almalu Trastevere is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Viminale Di Pepi Maurilio ensures a night out tailored to your taste.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 3
- Rome
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Drive 9 km, 59 min
- St Peter's Basilica
- Sistine Chapel
- Vatican Museums
- Piazza Navona
- Trastevere
- Monti
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At the end of the day, you'll drive back to Rome, where you'll stay for 1 night more.
Don’t miss Trastevere in Vatican City today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks. While you’re in the area, consider visiting Monti, another neighborhood that adds to the charm of Vatican City.
Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at St. Peter's Basilica.
If you’re looking for more, spend time soaking in the atmosphere of Piazza Navona. This history-steeped public square is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.
Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.
Extend your evening after a delightful meal by visiting Sant' Eustachio Caffè, which offers the perfect atmosphere for a night out. Moreover, Yellowsquare Rome is another popular option for a drink or two. Likewise, Caffè Portofino also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Savor another day of unforgettable experiences in Italy!
Day 4
- Rome
- Florence
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Drive 276 km, 3 hours 31 min
- Basilica of Santa Croce in Florence
- Uffizi Gallery
- Ponte Vecchio
- Piazza della Repubblica
- Cathedral of Santa Maria del Fiore
- piazza della Signoria
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Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.
Immerse yourself in Rome’s rich culture with today's sightseeing itinerary. Start your journey at Basilica Of Santa Croce In Florence. This culturally significant church is sure to ignite your curiosity. Next, dive into the picture-perfect features of Uffizi Gallery, a must-visit art gallery in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ponte Vecchio, a wondrous historical landmark. For a change of scene, check out Piazza Della Repubblica, known for its history-steeped features. We also recommend visiting Cathedral Of Santa Maria Del Fiore. This church is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Piazza Della Signoria, yet another extraordinary attraction in Rome.
When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at Ristorante Oliviero 1962, a highly-rated dining destination in Florence. If you're eager to try something different, consider Di Poneta Novoli, another top spot with a tantalizing menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.
Extend your evening after a delightful meal by visiting Manifattura, which offers the perfect atmosphere for a night out. Moreover, Se·sto On Arno Rooftop Bar is another popular option for a drink or two. Likewise, Il Vinile also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!
Day 5
- Florence
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Drive 183 km, 3 hours 8 min
- Piazza del Duomo, Pisa
- Pisa Cathedral
- Leaning Tower of Pisa
- Angelo Caduto
- Central Market
- piazzale Michelangelo
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Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Pisa and Florence.
Today’s well-planned self-sightseeing route offers several fun adventures, scenic views, and picturesque spots. Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Piazza Del Duomo, Pisa is the first of them. Spend some time admiring this picture-perfect public square before continuing your journey. Pisa Cathedral is your next stop. This often recommended church is one of the best-rated sights in Florence.
Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Leaning Tower Of Pisa. This culturally significant monument is a sight to behold. To round off your sightseeing experience, visit Angelo Caduto and Central Market. If time allows, end your day with Piazzale Michelangelo, a romantic observation deck that offers a memorable conclusion to your exploration.
When you’re done exploring for the day, you’ll return to Florence and your accommodation.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delightful dinner at Ditta Artigianale, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Da Burde? It's another excellent option with a diverse menu. Consider reserving a table at Casa Toscana as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.
Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 6
- Florence
- Pescara
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Drive 403 km, 5 hours 26 min
- Basilica of San Francesco d'Assisi
- Portico of Monte Frumentario
- Church of Santa Maria sopra Minerva in Assisi
- Piazza del Comune
- Rocca Maggiore
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Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Santa Maria degli Angeli. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Pescara. You will spend 1 night here for some well-deserved relaxation.
Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Basilica Of San Francesco D'assisi. This majestic church is a highlight of any visit in the town. Then, enjoy Portico Of Monte Frumentario, another culturally significant attraction that never fails to captivate visitors. Next, head over to Church Of Santa Maria Sopra Minerva In Assisi, one of the town’s most increasingly popular attractions, known for its culturally significant features.
If you’re looking for more, spend time soaking in the atmosphere of Piazza Del Comune. This grand public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Rocca Maggiore, a worthwhile castle, and take a stroll around the area.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Pescara. Pescara offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
Indulge in a memorable dining experience at one of Pescara's most popular restaurants, and connect with friendly locals for an authentic adventure.
Have a fantastic dining experience at Ciacco, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bar Sara offers an enticing alternative with its varied menu. Additionally, Ristorante Franco is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Pescara.
Keep the excitement of the evening going by visiting a bar or two. Bar Napoli is an excellent place to start. You could also check out Bar Supermarket, offering a different kind of charm. A last recommendation for the day is Post Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Relax and recharge in preparation for another adventurous day in Italy!
Day 7
- Pescara - Departure day
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- Parrocchia Spirito Santo
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Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This intriguing church is a popular place to see in the city.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Pescara's best shopping area, Centro Commerciale Pescara Porta Nuova. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.
Dine in style at MuuLab. Cucina e Distillati, a top recommendation for dinner tonight. Or, for a change of pace, La Taverna Antica boasts a menu that's sure to impress.
You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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