10-Day Italy Self-Drive Road Trip With Itinerary from Perugia to Santa Maria degli Angeli, Siena, Florence, and Lucca
Description
Included
Description
Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Perugia, Santa Maria degli Angeli, Spello, Siena, Florence, Pisa, Lucca, Corniglia, Vernazza, Manarola, and Orvieto. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Perugia, 1 night in Santa Maria degli Angeli, 1 night in Siena, 2 nights in Florence, and 2 nights in Lucca. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Piazza Del Duomo, Pisa, learn more about the unique Piazzale Michelangelo, and immerse yourself in the vibrant atmosphere of Cathedral Of Santa Maria Del Fiore.
As you hit the open road and drive through Perugia, Santa Maria degli Angeli, Spello, Siena, Florence, Pisa, Lucca, Corniglia, Vernazza, Manarola, and Orvieto, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Travel details
Set your travel details to find the best price
Flights
Compare and choose from the best flights to Perugia
Car
Choose from the best car rental deals or see all options
Itinerary summary
See a summary of the itinerary that you can fully customize
Personalize your itinerary
Customize tours under each day and destination
Day 1
- Perugia - Arrival day
- More
- Frontone Gardens
- More
Your road trip adventure in Italy begins as soon as you reach Perugia and pick up your car. You’ll stay in Perugia for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Frontone Gardens, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
As afternoon approaches, head to your chosen hotel in Perugia. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.
Enjoy a lovely dining experience at Ristorante Settimo Sigillo, a popular restaurant in Perugia. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Perugia at Caffè Baglioni, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Bar Pellas. It’s yet another ideal choice to enhance your time in Perugia tonight.
After savoring a delicious meal, step into the vibrant nightlife at Tommi Bar, where the evening is just getting started. In the same way, Valentina offers a unique charm perfect for experiencing the local bar scene in Perugia. Caffe Dal Perugino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Raise a toast to the start of your 10-day road trip in Italy!
Day 2
- Perugia
- More
Drive 2 km, 29 min
- The Fontana Maggiore
- Piazza IV Novembre
- National Gallery
- Carducci Gardens
- Rocca Paolina
- National Archaeological Museum of Umbria
- More
Day 2 offers a multitude of experiences. You will stay in Perugia for 1 night more, offering you enough time to explore at a relaxed pace.
Today’s agenda in Perugia includes a monument, a public square, an art gallery, a park, a historical landmark, a museum and much more! The Fontana Maggiore is must-visit monument and a great starting point for the day. Next, continue your journey to Piazza Iv Novembre, a worthwhile public square, located just a leisurely stroll away. Next, head to National Gallery, a visually striking art gallery, also available for your discovery today.
Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Perugia. When you're ready, let your sightseeing route take you to the locally appreciated Carducci Gardens. If you’re looking for more, Rocca Paolina is also an underrated attraction that is worthwhile a visit. Lastly, don’t miss National Archaeological Museum Of Umbria, a place of eye-catching interest in the city.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a wonderful meal at La Taverna, a top-rated dining spot in Perugia. If you're in the mood for something new, try Ristorante del Sole, another premier location with a delectable menu. You might also want to book a table at Al Mangiar Bene. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Perugia.
Let the evening flow smoothly from dinner to drinks at Caffè Fortebraccio, a top-rated bar in the area. For other recommendations, Caffe Del Banco provides a perfect setting for rounding out your night with style and great drinks. Likewise, Dempsey's Perugia offers a memorable night with diverse drink options and excellent service.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 3
- Perugia
- Assisi
- More
Drive 55 km, 1 hour 48 min
- Basilica of San Francesco d'Assisi
- Portico of Monte Frumentario
- Piazza del Comune
- Basilica di Santa Chiara
- Rocca Maggiore
- Porta Consolare
- More
Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Santa Maria degli Angeli and Spello. At the end of the day, you will enjoy the comforts of a top-rated hotel in Santa Maria degli Angeli, which will be your home away from home for 1 night.
Today, you'll explore some of the most beautiful places in Perugia, including a church, a historical landmark, a public square, a castle, a monument and much more! Start your day with a visit to Basilica Of San Francesco D'assisi. This well-known church is a must-visit in the town. When you’re ready for your next discovery, continue to Portico Of Monte Frumentario, which may be one of the most culturally significant places you will experience today.
One of the best things about exploring Perugia on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Piazza Del Comune, an increasingly popular public square in the town. If you’re up for more discoveries, don’t forget to reserve some time for Basilica Di Santa Chiara and Rocca Maggiore. End your day with a visit to Porta Consolare, an underrated monument that’s sure to leave a lasting impression.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Santa Maria degli Angeli. Santa Maria degli Angeli offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As dinnertime approaches, it's time to head out for a bite to eat in Santa Maria degli Angeli. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, known for its inviting atmosphere.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 4
- Assisi
- Siena
- More
Drive 132 km, 2 hours 19 min
- Palazzo Salimbeni
- Fortezza Medicea
- Basilica of San Domenico
- Siena Cathedral
- piazza del Campo
- Tower of Mangia
- More
Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Siena. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 1 night here for some well-deserved relaxation.
A blend of family-friendly attractions, photo-friendly spots, and historic treasures await you in Santa Maria degli Angeli on today’s itinerary. First up is the worthwhile palace, Palazzo Salimbeni. Afterward, continue to Fortezza Medicea (siena), a monument every traveler should visit.
As you explore Santa Maria degli Angeli’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Basilica Of San Domenico. This locally appreciated church is an essential stop. Following that, head to Siena Cathedral, another must-visit site that will enhance your experience. Don’t forget to stop by Piazza Del Campo, an impressive public square in the city. Finally, end your day with a visit to Tower Of Mangia, an UNESCO world heritage-designated monument that offers the perfect conclusion to your sightseeing of the day.
When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.
Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a delicious meal at Enoteca I Terzi, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Ristorante Tar-Tufo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.
Following your dinner, dive into the local bar culture at Meet Life Cafè. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Maudit Pub, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Impero Siena provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Raise your glass to another unforgettable day in Italy!
Day 5
- Siena
- Florence
- More
Drive 73 km, 1 hour 26 min
- Palazzo Pitti
- Ponte Vecchio
- Uffizi Gallery
- Basilica of Santa Croce in Florence
- piazza della Signoria
- More
On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 2 nights.
Siena is home to plenty of attractions that offer fun adventures, romantic experiences, and scenic views! Start at Pitti Palace, a locally renowned palace that is worthwhile a visit in the city. Nearby, you’ll find Ponte Vecchio, enchanting visitors with its visually striking appeal. Continue your exploration at Uffizi Gallery. This art gallery is one of the city’s most widely recognized spots.
Enjoy the freedom of exploring Siena at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Basilica Of Santa Croce In Florence. After exploring the church, head to the astonishing Piazza Della Signoria.
At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.
To truly maximize your evening out, consider visiting Manifattura after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Se·sto On Arno Rooftop Bar, another bar with an inviting ambiance. Similarly, Il Vinile also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Say good night to Florence and look forward to another great day of your road trip in Italy!
Day 6
- Florence
- More
Drive 11 km, 1 hour 6 min
- Basilica of Santa Maria Novella
- Central Market
- Cathedral of Santa Maria del Fiore
- Galleria dell'Accademia
- David
- piazzale Michelangelo
- More
On day 6 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.
Set out on a day brimming with fun adventures, romantic experiences, and scenic views. Start at the locally renowned Basilica Di Santa Maria Novella, Firenze (fi), a visually striking church in Florence. Next, go to Central Market.
After visiting Basilica Di Santa Maria Novella, Firenze (fi) and Central Market, have a stroll along Florence's streets and take in the local charm. Continue your sightseeing by heading to Cathedral Of Santa Maria Del Fiore. This visually striking church offers a unique experience. Galleria Dell'accademia is another noteworthy attraction worthwhile a visit. If you still have some time left for sightseeing, we also recommend stopping by Piazzale Michelangelo.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Treat yourself to a delightful dinner at Ditta Artigianale, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Da Burde? It's another excellent option with a diverse menu. Consider reserving a table at Casa Toscana as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.
Continue the enjoyment post-dinner at Bar 50 Rosso, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bitter Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Archea Brewery. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 7
- Florence
- Lucca
- More
Drive 107 km, 2 hours 14 min
- Pisa Cathedral
- Piazza del Duomo, Pisa
- Leaning Tower of Pisa
- Walls of Lucca
- St Martin Cathedral
- Piazza dell'Anfiteatro
- More
On day 7 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pisa and Lucca. In the evening, you’ll end up in Lucca, where you will stay for 2 nights.
Prepare for a day full of family-friendly attractions, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Pisa Cathedral. This underrated church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Piazza Del Duomo, Pisa, one of the city’s best highlights.
Next, check out Leaning Tower Of Pisa, one of the most wondrous places to see in Florence. This monument is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Mura Di Lucca. Wander around and soak in the culturally significant atmosphere this historical landmark offers. Then, head to St Martin Cathedral, a top-rated church that adds another dimension to your day. Finally, visit the locally renowned Piazza Dell'anfiteatro, the last of our attraction recommendations for today.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Lucca. Lucca offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Lucca's best restaurants.
Make sure to reserve a table at Gli Orti di Via Elisa, an iconic dining spot in Lucca. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bar Caffè Ristretto, a popular restaurant in Lucca. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Schiaffino, a hidden gem nestled in Lucca. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Keep the excitement of the evening going by visiting a bar or two. Lebowski - Cocktail Bar is an excellent place to start. You could also check out Blend, offering a different kind of charm. A last recommendation for the day is Franklin'33. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Head back to your accommodation in Lucca and get some rest in preparation for another magical day of your road trip in Italy!
Day 8
- Lucca
- More
Drive 219 km, 4 hours 10 min
- Scalinata Lardarina
- Chiesa Di San Pietro
- Ruins of Doria Tower
- Church of St. Margaret of Antioch
- Cinque Terre National Park
- Manarola Overlook Viewpoint
- More
At the end of the day, you'll drive back to Lucca, where you'll stay for 1 night more.
Start by visiting Scalinata Lardarina, a prime spot to begin your journey. This romantic hiking area is sure to impress. Next on your list is Chiesa Di San Pietro, another must-visit landmark and curiosity-inducing church renowned for its history-steeped features.
While exploring and sightseeing, take time to savor the culture of Lucca by sampling some local delicacies. When you’re ready for more sightseeing, head to Ruins Of Doria Tower. This history-steeped monument is an essential place to visit for anyone looking for the full Lucca experience. We also recommend visiting Church Of St. Margaret Of Antioch, an up-and-coming church. Nearby, you'll also find Cinque Terre National Park, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Manarola Overlook Viewpoint and wrap up your day with its eye-catching appeal.
When you’re done exploring for the day, you’ll return to Lucca and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lucca. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a wonderful meal at Osteria Nova, a top-rated dining spot in Lucca. If you're in the mood for something new, try La Bottega di Anna e Leo, another premier location with a delectable menu. You might also want to book a table at Ristorante Per 21. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lucca.
Explore the vibrant nightlife at La Tana Del Boia after your meal, a hub for lively evenings and memorable moments. Or, head to Vinarkia Della Pavona - Cocktail Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Magellano is perfect for those looking to extend their night with a touch of local flavor.
Say good night to Lucca and look forward to another great day of your road trip in Italy!
Day 9
- Lucca
- Perugia
- More
Drive 317 km, 4 hours 20 min
- Well of St Patrick
- Orvieto Cathedral
- Museo dell'Opera del Duomo
- Orvieto subterranea
- Torre del Moro Orvieto
- Pozzo della Cava
- More
Dive into day 9 of your remarkable road trip in Italy. Today you will explore Orvieto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Perugia. You’ll stay here for 1 night.
Today’s route brings fun adventures, breathtaking views, and photo-friendly spots. The first attraction of today is Well Of St. Patrick. This well-known monument is a breathtaking place to see in Lucca. Continue your discovery at Orvieto Cathedral, a visually striking church with stories to tell.
As you stroll around Lucca, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Museo Dell'opera Del Duomo. This locally appreciated museum offers a photogenic encounter with Lucca. Next, make your way to Orvieto Underground to add another highlight to your day. After that, visit Torre Del Moro Orvieto, a frequently visited monument that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Pozzo Della Cava, an intriguing cave in the village. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Lucca.
When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Perugia, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at Perugia Plaza Hotel, a highly-rated dining destination in Perugia. If you're eager to try something different, consider Elfo Pub Perugia, another top spot with a tantalizing menu. You might also want to secure a reservation at Sangallo Palace Hotel. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Perugia this evening.
Let the evening flow smoothly from dinner to drinks at Il Birrino, a top-rated bar in the area. For other recommendations, Quei Bravi Ragazzi provides a perfect setting for rounding out your night with style and great drinks. Likewise, Lo Chalet - Lounge Bar offers a memorable night with diverse drink options and excellent service.
Celebrate another amazing day of your road trip adventure in Italy!
Day 10
- Perugia - Departure day
- More
- Etruscan Arch
- More
Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Etruscan Arch. This up-and-coming historical landmark is a popular place to see in the city.
On your last day in Italy, take time to indulge in shopping at Perugia’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
Dine in style at Alphaville, a top recommendation for dinner tonight. Or, for a change of pace, Osteria a Priori boasts a menu that's sure to impress.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
Similar travel packages
Discover other popular vacations in Italy
Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place
Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.