12-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, San Gimignano, Santa Maria degli Angeli, and Rome

Day 2 of your road trip across Italy promises a magnificent time exploring Genoa. You have 1 night left in Genoa. Take the opportunity to experience more of the best attractions and activities in the city.

Discover a day packed with family-friendly attractions, scenic views, and photo-friendly spots in Genoa. Begin your sightseeing with Lighthouse Of Genoa. This up-and-coming lighthouse is one of the top attractions in the city. Proceed to Royal Palace Museum, another must-visit attraction.

As you wander through the inviting streets of Genoa, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Via Garibaldi. This underrated street is a traveler-favorite. Not far away, you’ll find Palazzo Podestà, another key site on your sightseeing itinerary. Aquarium Of Genoa is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Porto Antico and uncover why it's recognized as one of the city's most notable attractions.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Zeffirino, a top-rated dining spot in Genoa. If you're in the mood for something new, try Trattoria Vegia Zena, another premier location with a delectable menu. You might also want to book a table at Trattoria delle Grazie. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Genoa.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vernazza, Corniglia, Manarola, and Riomaggiore. In the evening, you’ll end up in La Spezia, where you will stay for 1 night.

Start your adventure at Ruins Of Doria Tower. This often recommended monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the picture-perfect wonders of Church Of St. Margaret Of Antioch, a must-see church in the village.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Cinque Terre National Park. This popular national park offers an enriching experience. For a change of pace, head to Manarola Overlook Viewpoint, where you can take in romantic features. Conclude your self-guided sightseeing tour with a visit to Riomaggiore and Church Of San Giovanni Battista Of Riomaggiore. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in La Spezia. La Spezia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in La Spezia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at The Colombaio Park, a top-rated dining destination in La Spezia.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 2 nights.

Brace yourself for today’s incredible lineup of attractions in La Spezia, featuring fun adventures, romantic experiences, and breathtaking views. Start at Santa Maria Della Spina, a worthwhile church in the city. Then, head to Palazzo Blu and soak in the ambiance of this eye-catching art gallery.

There are many interesting places to see in La Spezia, and when you are ready for more, go to Knights' Square. This is one of the city’s most worthwhile instagrammable spots of interest. After exploring the public square, visit the timeless Leaning Tower Of Pisa. Not far away, you'll also find Piazza Del Duomo, Pisa. This public square is a breathtaking highlight in La Spezia. Before wrapping up your self-guided sightseeing tour, head to Pisa Cathedral, a beloved church in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 5 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in Florence by discovering the best things there are to see and do in the city.

Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Cathedral Of Santa Maria Del Fiore. This enchanting church is sure to ignite your curiosity. Next, dive into the romantic features of Piazza Della Signoria, a must-visit public square in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Palazzo Vecchio, an interesting palace. For a change of scene, check out Ponte Vecchio, known for its visually striking features. We also recommend visiting Uffizi Gallery. This art gallery is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Basilica Of Santa Croce In Florence, yet another interesting attraction in Florence.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Ditta Artigianale, a highly-rated dining destination in Florence. If you're eager to try something different, consider Trattoria Da Burde, another top spot with a tantalizing menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Siena and San Gimignano. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in San Gimignano. You will spend 2 nights here for some well-deserved relaxation.

Get ready to discover some of the most iconic wonders in Florence, including a church, a public square, a monument, a library and much more! Start your day at Basilica Of San Domenico. This majestic church is an intriguing place to see in Florence. Then, wander over to Piazza Del Campo. If history-steeped sites excite you, this public square will be right up your alley. Nearby, you’ll also find Tower Of Mangia. This UNESCO world heritage-listed monument is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Siena Cathedral is a captivating spot in the city that will captivate you with its unique charm. When you’re done at the church, don’t forget to check out the standout Piccolomini Library. Take a moment to appreciate the fascinating details of this beloved library. Wrap up your self-guided tour of Florence's top attractions with a visit to Porta San Giovanni.

At the end of the day, you will drive to San Gimignano, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of San Gimignano's best restaurants.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 7 of your road trip, you will have an entire day to explore San Gimignano. You’ll stay in San Gimignano for 1 night and discover all the best things to see and do in the area.

Bring your curiosity for today’s adventure around San Gimignano. Some of the village’s most loved attractions await! Piazza Del Duomo is the perfect place to start. This public square is one of the most curiosity-inducing places to visit in San Gimignano. Next, head to Palazzo Comunale, Pinacoteca, Torre Grossa, a locally appreciated museum, known for its breathtaking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Sangimignano1300. This heritage-rich museum is a highly recommended experience. Nearby, you'll also find Parco Della Rocca and Rocca Di Montestaffoli. Visit these for an interesting touch to your journey. Finish the day with a visit to Chiesa Di Sant'agostino, a photogenic church in San Gimignano.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of San Gimignano's best restaurants.

Savor another day of unforgettable experiences in Italy!

Embark on another extraordinary experience on day 8 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Santa Maria degli Angeli. At the end of the day, you will enjoy the comforts of a top-rated hotel in Santa Maria degli Angeli, which will be your home away from home for 1 night.

Begin your adventure at Basilica Of Santa Maria Degli Angeli. This is a locally renowned church you should not miss. Another must-see is Basilica Of San Francesco D'assisi, a notable church in San Gimignano.

When you’re ready for the next sight, head to Porta San Giacomo. From there, take a leisurely stroll to Portico Of Monte Frumentario, another of the village’s increasingly popular attractions. We recommend continuing your self-guided tour at Rocca Maggiore, a symbolic place of interest in the village. If time allows, add Piazza Del Comune to your itinerary. This increasingly popular public square offers the perfect finishing touch to your day in San Gimignano.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Santa Maria degli Angeli. Santa Maria degli Angeli offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Santa Maria degli Angeli. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

After savoring a delicious meal, step into the vibrant nightlife at Bibenda Assisi Wine Tasting & Gourmet Food, Olive Oil And Chocolate Tastings, where the evening is just getting started.

Celebrate another amazing day of your road trip adventure in Italy!

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Rome. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 2 nights.

Prepare for a day full of fun adventures, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Colosseum. This globally renowned archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Roman Forum, one of the city’s best highlights.

Next, check out Pantheon, one of the most world-famous places to see in Santa Maria degli Angeli. This monument is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazza Di Spagna. Wander around and soak in the history-steeped atmosphere this public square offers. Then, head to Piazza Del Popolo, a top-rated public square that adds another dimension to your day.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at La Bottega Roma, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pasta In Corso? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Vecchia Roma as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 10 of your road trip, you’ll start and end your day in Rome, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Vatican City and Rome. You still have 1 night left in Rome.

A blend of fun adventures, romantic experiences, and breathtaking views await you in Rome on today’s itinerary. First up is the wondrous art museum, Vatican Museums. Afterward, continue to St. Peter's Basilica, a major basilica every traveler should visit.

As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Sistine Chapel. This impressive chapel is an essential stop. Following that, head to Castel Sant'angelo, another must-visit site that will enhance your experience. Don’t forget to stop by Piazza Navona, a globally renowned public square in the city. Finally, end your day with a visit to Trevi Fountain, a detailed monument that offers the perfect conclusion to your sightseeing of the day.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at RomAntica, a highly-rated dining destination in Rome. If you're eager to try something different, consider Coso Ristorante, another top spot with a tantalizing menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

After enjoying a fulfilling meal, continue your evening at Sant' Eustachio Caffè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Yellowsquare Rome offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffè Portofino provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 11 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Orvieto. In the evening, you’ll end up in Genoa, where you will stay for 1 night.

Start by visiting Well Of St. Patrick, a prime spot to begin your journey. This culturally significant monument is sure to impress. Next on your list is Orvieto Cathedral, another must-visit landmark and locally renowned church renowned for its visually striking features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Orvieto Underground. This photogenic cave system is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Torre Del Moro Orvieto, a worthwhile monument. Nearby, you'll also find Pozzo Della Cava, ready to add charm to your journey.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Osteria Sant'Ilario, an excellent option for tonight's dining. Looking for something different? La Cialtroneria offers a tantalizing alternative with its diverse menu. And don’t miss Manhattan Bar. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Genoa.

Get a good night's sleep and look forward to another great day on the road in Italy!