4-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence

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Photo of Sand beach in Camogli by Genoa, Italy.
Photo of Piazza De Ferrari main square in Genoa Italy.
Photo of Courtyard of Palazzo Reale in Genoa, Italy.
Photo of View of Genoa at sunset from "Spianata Castelletto", Italy.
Photo of Sestri Levante - Paradise Bay of Silence with its boats and its lovely beach. Beautiful coast at Province of Genoa in Liguria, Italy - Europe.
Photo of Genoa, Liguria, Italy downtown city skyline from above at dusk.
Photo of The Aquarium of Genoa is the largest aquarium in Italy. Located in the old harbor area of Genova.
Photo of Genoa port from above at night.
Photo of Palace of St George (Palazzo San Giorgio), Genoa, Italy.
Photo of Genova Brignole Railway Station in the evening.
Photo of View of Bogliasco. Bogliasco is a ancient fishing village in Italy, Genoa, Liguria. Mediterranean Sea, sandy beach and architecture of Bogliasco town.
Photo of Beach with tourists in San Fruttuoso bay with the ancient Abbey (San Fruttuoso di Capodimonte), X-XI century, and Andrea Doria tower. Portofino and Camogli, Genoa province, Liguria, Italy, Europe.
Photo of View of Pieve Ligure and on Sori on the background, italian towns of ligurian riviera, Genoa (Genova) province, Italy.
photo of view of Bogliasco, Genoa, Italy town skyline on the Mediterranean sea at sunset.
Aerial view of the Cattedrale di Santa Maria del Fiore in Florence, Italy, overlooking the city
Photo of Florence Aerial View of Ponte Vecchio Bridge during Beautiful Sunny Day, Italy.
Photo of Woman enjoys beautiful view on famous Duomo cathedral in Florence, standing on empty cathedral square during morning time.
Photo of Summer street cafe on Piazza della Repubblica in Florence, Toscana province, Italy.
Photo of Giotto's Campanile - An aerial dusk view of Giotto's Campanile and the historical Old Town of Florence, as seen from the top of Brunelleschi's Dome of the Florence Cathedral. Florence, Tuscany, Italy.
Photo of Ponte Vecchio, old bridge over Arno River, Florence, Tuscany, Italy.
Photo of The Colossus of the Apennines, majestic stone sculpture by Giambologna located in the park of Villa Demidoff in Florence, Italy.
Photo of Fountain of Neptune in Florence in early morning.
Photo of Sunset view of Florence, Ponte Vecchio, Palazzo Vecchio and Florence Duomo, Italy. Architecture and landmark of Florence. Cityscape of Florence.
Vintage carousel and tourists in Piazza della Repubblica (Republic Square) and the arch in honor of the first king of united Italy on background in Florence, Italy.
Photo of Arches of the Vasari Corridor (Corridoio Vasariano) in Florence, Tuscany, Italy. View of the Lungarno degli Archibusieri.
cheerful senior woman cycling with her electric mountain bike above downtown of Florence with stunning view over the old city, Tuscany, Italy
Facade of Palazzo Pitti palace with Gallery of Modern Art large building on Piazza dei Pitti square in historical centre of Florence city, blue sky white clouds, Tuscany, Italy
photo of view of Florence,Italy.
photo of view of Florence,Italy.
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Explore the best of Italy on a 4-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Genoa and Florence. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Genoa and 1 night in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Piazzale Michelangelo are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Cathedral Of Santa Maria Del Fiore, learn more about the unique Piazza Della Signoria, and immerse yourself in the vibrant atmosphere of Aquarium Of Genoa.

As you hit the open road and drive through Genoa and Florence, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Via Garibaldi
piazza De FerrariGenoa CathedralAquarium of Genoaporto antico
piazza della SignoriaPonte VecchioCathedral of Santa Maria del FioreCentral Marketpiazzale Michelangelo
Piazza della Vittoria

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Day 1

Day 1

  • Genoa - Arrival day
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  • Via Garibaldi
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Say hello to Genoa! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Genoa for 1 night before you continue your adventure!

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Via Garibaldi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Genoa. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at 7 Sensi cucina decontaminata, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider Alla Lunga Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Grand Hotel Savoia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

Let the evening flow smoothly from dinner to drinks at Scurreria Beer & Bagel, a top-rated bar in the area. For other recommendations, La Lepre provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Pisacane Iii offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 4-day road trip in Italy!

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Day 2

Day 2

  • Genoa
  • Florence
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Drive 262 km, 3 hours 25 min

  • piazza De Ferrari
  • Genoa Cathedral
  • Aquarium of Genoa
  • porto antico
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Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Genoa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 1 night.

Today’s route brings family-friendly attractions, romantic experiences, and breathtaking views. The first attraction of today is Piazza De Ferrari. This captivating public square is a symbolic place to see in Genoa. Continue your discovery at Genoa Cathedral, a culturally significant church with stories to tell.

As you stroll around Genoa, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Aquarium Of Genoa. This impressive aquarium offers a visually striking encounter with Genoa. Next, make your way to Porto Antico to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Genoa.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Experience a harmony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Known for its 3-star Michelin status, Enoteca Pinchiorri offers a delightful variety of dishes highlighting its delicious italian contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Santa Elisabetta, a highly recommended restaurant known for its enticing creative and mediterranean cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Gucci Osteria da Massimo Bottura, a highly acclaimed restaurant celebrated for its exceptional italian contemporary and international menu.

Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day 3

Day 3

  • Florence
  • Genoa
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Drive 248 km, 3 hours 32 min

  • piazza della Signoria
  • Ponte Vecchio
  • Cathedral of Santa Maria del Fiore
  • Central Market
  • piazzale Michelangelo
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On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Genoa, where you will stay for 1 night.

Savor the day by visiting some of the best places to see in Florence, including a public square, a historical landmark, a church, a food market, an observation deck and much more! Start your adventure at Piazza Della Signoria. This top-rated public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Ponte Vecchio located in Florence for another exciting encounter.

Next, immerse yourself in the setting of Cathedral Of Santa Maria Del Fiore. Its history-steeped features will captivate you. After the church, continue your tour of the city with a visit to Central Market. Visitors usually appreciate the instagrammable features of this food market. Next up is Piazzale Michelangelo, a highly recommended observation deck.

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to an extraordinary dining experience at San Giorgio, a 1-star Michelin restaurant offering an incredible modern and ligurian menu. Alternatively, if your taste buds call for something different, The Cook is one of the best restaurants for modern cuisine in Genoa. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Il Marin. As a top-rated establishment with 1 Michelin star, it is an ideal choice for seafood and contemporary cuisine in the city.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 4

Day 4

  • Genoa - Departure day
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  • Piazza della Vittoria
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Day 4 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Piazza Della Vittoria, a symbolic public square before you head out.

On your last day in Italy, take time to indulge in shopping at Genoa’s popular marketplace, Via Garibaldi. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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