5-Day Italy Self-Drive Road Trip With Itinerary from Ancona traveling south to L'aquila and Rome

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Experience the freedom of the open road in Italy as you embark on an unforgettable 5-day road trip! This experience caters to every traveler, featuring destinations like Ancona, Senigallia, Loreto, L'aquila, Rome, Tivoli, and Teramo.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Ancona, 1 night in L'aquila, and 1 night in Rome. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ancona, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. St. Peter's Basilica and Vatican Museums are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Sistine Chapel, learn more about the unique Saint Peter's Square, and immerse yourself in the vibrant atmosphere of Villa D'este.

As you hit the open road and drive through Ancona, Senigallia, Loreto, L'aquila, Rome, Tivoli, and Teramo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
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Day
City & Overnight
Attractions
Passetto
Cattedrale di San CiriacoLazzaretto of AnconaRocca RoverescaSanctuary of the Holy House of Loreto
Vatican MuseumsSaint Peter's SquareSistine ChapelSt Peter's Basilica
Hadrian's VillaVilla d'EsteSantuario Madonna Delle Grazie
Piazza del Plebiscito

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Day 1

Day 1

  • Ancona - Arrival day
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  • Passetto
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Your road trip adventure in Italy begins as soon as you reach Ancona and pick up your car. You’ll stay in Ancona for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Ancona is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Passetto, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Ancona. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ancona, it's often a good idea to reserve a table in advance.

Dine in style at Playa Solero, a top recommendation for dinner tonight. Or, for a change of pace, Zucchero a Velò boasts a menu that's sure to impress. Also, be sure to check out Ristorante Il Giardino. Known as a local hotspot, it’s a great choice for tonight in Ancona.

Round off your dining experience by visiting Posa Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bar Four Roses, a bar catering to every mood and preference. Amarillo Beer Bar Ancona likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 5-day road trip in Italy!

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Day 2

Day 2

  • Ancona
  • L'Aquila
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Drive 257 km, 3 hours 57 min

  • Cattedrale di San Ciriaco
  • Lazzaretto of Ancona
  • Rocca Roveresca
  • Sanctuary of the Holy House of Loreto
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Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Ancona, Senigallia, and Loreto. At the end of the day, you will enjoy the comforts of a top-rated hotel in L'aquila, which will be your home away from home for 1 night.

Bring your curiosity for today’s adventure around Ancona. Some of the city’s most loved attractions await! Cathedral Basilica Of St. Cyriacus is the perfect place to start. This church is one of the most increasingly popular places to visit in Ancona. Next, head to Lazzaretto Of Ancona, an intriguing museum, known for its symbolic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Rocca Roveresca. This historic castle is a highly recommended experience. Nearby, you'll also find Sanctuary Of The Holy House Of Loreto. Visit these for an interesting touch to your journey.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in L'aquila. L'aquila offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of L'aquila's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a memorable dining experience in L'aquila by booking a table at FØRMA contemporary restaurant, renowned as a Bib Gourmand restaurant presenting an exceptional contemporary and creative menu. Immerse yourself in the culinary delights of DECA, a popular restaurant in L'aquila. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Extend your evening after a delightful meal by visiting Art Cafè L'aquila, which offers the perfect atmosphere for a night out.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • L'Aquila
  • Rome
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Drive 135 km, 2 hours 21 min

  • Vatican Museums
  • Saint Peter's Square
  • Sistine Chapel
  • St Peter's Basilica
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On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Vatican City. In the evening, you’ll end up in Rome, where you will stay for 1 night.

Vatican Museums is must-visit art museum and a great starting point for the day. Next, continue your journey to Saint Peter's Square, an interesting square, located just a leisurely stroll away.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a taste of local culinary excellence while in Rome by securing a table at La Pergola. An esteemed 3-star Michelin restaurant, it features an exceptional mediterranean and contemporary menu. For an alternative taste experience, visit Il Pagliaccio, famous for its scrumptious creative and innovative dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Enoteca La Torre, a local favorite celebrated for its exquisite mediterranean and creative cuisine in Rome. Located in the heart of the city, this 2-star Michelin restaurant is an ideal pick for mediterranean and creative cuisine lovers seeking top-notch culinary experiences.

Keep the excitement of the evening going by visiting a bar or two. La Botticella Of Poggi Giovanni is an excellent place to start. You could also check out Almalu Trastevere, offering a different kind of charm. A last recommendation for the day is Bar Viminale Di Pepi Maurilio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 4

Day 4

  • Rome
  • Ancona
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Drive 318 km, 4 hours 12 min

  • Hadrian's Villa
  • Villa d'Este
  • Santuario Madonna Delle Grazie
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Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Tivoli and Teramo. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ancona. You will spend 1 night here for some well-deserved relaxation.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to Hadrian's Villa. This frequently visited archeological site provides an insightful glimpse into the town's identity. Next, discover Villa D'este, an enchanting palace, promising a delightful encounter.

Continue your sightseeing with a visit to Santuario Madonna Delle Grazie, an often recommended church.

When you’re done exploring for the day, you’ll drive to your hotel in Ancona. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ancona. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Begin your culinary exploration in Ancona by securing a reservation at Sot'Ajarchi. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of seafood and from the marches cuisine. Or, for a change of pace, Bontà delle Marche boasts a menu that's sure to impress.

Round off your dining experience by visiting Alla Tazza D'oro, a prime location for a drink.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 5

Day 5

  • Ancona - Departure day
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  • Piazza del Plebiscito
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Day 5 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Ancona before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Piazza Del Plebiscito. This frequently visited public square is a popular place to see in the city.

Maximize your last day in Italy and go on a shopping spree in Ancona’s shopping center. Browse for souvenirs to remind you of your wonderful journey in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Ancona.

If you're in the mood to try something new, consider Donegal Irish Pub, another top spot with a mouthwatering menu.

You’ll then say farewell to Ancona. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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