6-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence, L'aquila, and Naples and surrounding area

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Photo of piazza de spagna in Rome, Italy.
Photo of Fountain di Trevi in Rome, Italy.
Bridge Il Tevere a Ponte Vittorio Emanuele II in Rome, Italy.
Hadrian Mausoleum, Rome, Italy.
 Vatican dome of San Pietro and Sant Angelo Bridge, over Tiber river in Rome, Italy.
panoramic view of Rome and St. Peter's Basilica, Italy.
View of Pantheon in the morning, Rome, Italy.
Rome, Italy. Stunning twilight view of Forum ancient ruins, seen from Capitoline hill with Colosseum in background.
Aerial view of forum romanum and surrounding areas of historical centre of italian capital rome.
Cozy old street in Trastevere in Rome, Italy. Trastevere is rione of Rome, on the west bank of the Tiber in Rome, Lazio, Italy. Architecture and landmark of Rome.
Aerial panorama of St. Peter's Square in Vatican with Rome in the background. Italy.
photo of view of Illuminated Fontana Di Trevi, Trevi Fountain at Dusk, Rome, Italy.
photo of view of Spanish Step, Rome, Italy.
photo of view of Museum Luasanne, Rome, Italy.
photo of view Roma Wall of Lugo, Rome, Italy.
photo of view of Roman Bridge Cordoba, Rome, Italy.
photo of view of Roman ruins in Rome, Forum, Rome, Italy.
photo of view of Roman Bridge of Cordoba, Rome, Italy.
photo of view of The Iconic, the legendary Coliseum of Rome, Italy.
photo of view of Rome, Italy: The Roman Forum, Latin: Forum Romanum, Italian: Foro Romano, Rome, Italy.
photo of view of Trevi Fountain (Fontana di Trevi) in Rome, Italy. Trevi is most famous fountain of Rome. Architecture and landmark of Rome, Postcard of Rome, Italy.
Aerial view of the Cattedrale di Santa Maria del Fiore in Florence, Italy, overlooking the city
Photo of Florence Aerial View of Ponte Vecchio Bridge during Beautiful Sunny Day, Italy.
Photo of Woman enjoys beautiful view on famous Duomo cathedral in Florence, standing on empty cathedral square during morning time.
Photo of Summer street cafe on Piazza della Repubblica in Florence, Toscana province, Italy.
Photo of Giotto's Campanile - An aerial dusk view of Giotto's Campanile and the historical Old Town of Florence, as seen from the top of Brunelleschi's Dome of the Florence Cathedral. Florence, Tuscany, Italy.
Photo of Ponte Vecchio, old bridge over Arno River, Florence, Tuscany, Italy.
Photo of The Colossus of the Apennines, majestic stone sculpture by Giambologna located in the park of Villa Demidoff in Florence, Italy.
Photo of Fountain of Neptune in Florence in early morning.
Photo of Sunset view of Florence, Ponte Vecchio, Palazzo Vecchio and Florence Duomo, Italy. Architecture and landmark of Florence. Cityscape of Florence.
Vintage carousel and tourists in Piazza della Repubblica (Republic Square) and the arch in honor of the first king of united Italy on background in Florence, Italy.
Photo of Arches of the Vasari Corridor (Corridoio Vasariano) in Florence, Tuscany, Italy. View of the Lungarno degli Archibusieri.
cheerful senior woman cycling with her electric mountain bike above downtown of Florence with stunning view over the old city, Tuscany, Italy
Facade of Palazzo Pitti palace with Gallery of Modern Art large building on Piazza dei Pitti square in historical centre of Florence city, blue sky white clouds, Tuscany, Italy
photo of view of Florence,Italy.
photo of view of Florence,Italy.
Twilight panorama of Naples in Italy
Photo of Morning view of Amalfi cityscape on coast line of mediterranean sea, Italy.
Photo of View of Piazza del Plebiscito, Naples,Italy.
Panoramic view of the ancient city of Pompeii with houses and streets. Pompeii is an ancient Roman city died from the eruption of Mount Vesuvius in the 1st century. Naples, Italy.
Photo of Panorama of Naples, view of the port in the Gulf of Naples and Mount Vesuvius. The province of Campania. Italy.
Photo of Maschio Angioino Castle in Naples during a sunny sunrise.
Photo of Obelisk Guglia of the Immaculate Virgin on Piazza Gesu Nuovo in Naples (Napoli), Italy.
Photo of Boats at Marina Grande embankment in Capri Island in Tyrrhenian sea, Italy.
Photo of Stunning rooftop view of Naples from above during sunset.
Photo of Kilometers-long promenade along cascades at the Palace of Caserta, Italy.
Photo of The neighborhood called Quartieri Spagnoli in Naples, Italy. Street view of old town. Narrow street of Napoli. Bright sunny day. Gulf of Naples, blue sky, sea on background. Cacti on the terrace.
Photo of Sunset in Positano, Amalfi Coast, Salerno - Naples, Italy.
Photo of Ancient ruins of Pompei city (Scavi di Pompei), Naples, Italy.
photo of view of Colorful architecture in Naples city, Italy. Summer cityscape at sunset. Famous travel destination.
photo of view of Panoramic view of Naples city and Gulf of Naples, Italy. Blue sea and the sky with clouds at sunset. Famous travel destination.
Panoramic autumnal view in Barrea, province of L'Aquila in the Abruzzo region of Italy.
The Castle of Rocca Calascio is a mountaintop fortress or rocca in the municipality of Calascio, in the Province of L'Aquila, Abruzzo, Italy.
Basilica of Santa Maria di Collemaggio - L'Aquila - Italy
Beautiful panoramic view in the village of Barrea, province of L'Aquila in the Abruzzo region of Italy.
Lake San Domenico, in the Sagittario Gorges, in Abruzzo, L'Aquila, Italy. The small hermitage with the stone bridge. The turquoise color of the water. The glow of the sun, flare at sunset.
Gran Sasso freeway in Abruzzo,L-aquila, Italy
The enchanting Lake Scanno, in Abruzzo, in the province of L'Aquila, located between the Marsican Mountains. The small Church of Santa Maria dell'Annunziata overlooks the waters of the lake.
Scenic sight in Pescasseroli, Abruzzo National Park, province of L'Aquila. Italy
Santa Maria del Soccorso Church in Tagliacozzo, province of L'Aquila, Abruzzo, Italy.
The church of Santa Maria della Pietà is a religious building located in the municipality of Calascio, in the province of L'Aquila, in Abruzzo,
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Explore the best of Italy on a 6-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Rome, Florence, L'aquila, and Naples. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Rome, 1 night in Florence, 1 night in L'aquila, and 1 night in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Rome, Florence, L'aquila, and Naples, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Trevi Fountain
Roman ForumPiazza di SpagnaColosseumPantheonPiazza Navona
piazza della SignoriaCathedral of Santa Maria del FiorePonte Vecchiopiazzale Michelangelo
St Peter's BasilicaSistine ChapelVatican Museums
piazza del PlebiscitoOvo CastleNaples National Archaeological MuseumCappella Sansevero
Altare della Patria

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Day 1

Day 1

  • Rome - Arrival day
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  • Trevi Fountain
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Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Rome's charm before embarking on the next leg of your journey.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Trevi Fountain, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Rome. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 6-day road trip in Italy!

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Day 2

Day 2

  • Rome
  • Florence
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Drive 290 km, 4 hours 6 min

  • Roman Forum
  • Piazza di Spagna
  • Colosseum
  • Pantheon
  • Piazza Navona
  • More

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 1 night here for some well-deserved relaxation.

Get ready to discover some of the most iconic wonders in Rome, including an archeological site, a public square, and a monument. Start your day at Roman Forum. This breathtaking archeological site is a world-famous place to see in Rome. Then, wander over to Piazza Di Spagna. If history-steeped sites excite you, this public square will be right up your alley. Nearby, you’ll also find Colosseum. This historic archeological site is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Pantheon is a globally renowned spot in the city that will captivate you with its unique charm. When you’re done at the monument, don’t forget to check out the enchanting Piazza Navona. Take a moment to appreciate the fascinating details of this globally renowned public square.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Florence by booking a table at Enoteca Pinchiorri, renowned as a 3-star Michelin restaurant presenting an exceptional italian contemporary menu. For a different culinary experience in Florence, Santa Elisabetta shines as one of the top destinations, known for its delicious creative and mediterranean cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Gucci Osteria da Massimo Bottura is known as a top local spot for its delicious italian contemporary and international cuisine in Florence. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 3

Day 3

  • Florence
  • L'Aquila
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Drive 365 km, 4 hours 29 min

  • piazza della Signoria
  • Cathedral of Santa Maria del Fiore
  • Ponte Vecchio
  • piazzale Michelangelo
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On day 3 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in L'aquila, where you will stay for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Florence allows for both. Start by heading to Piazza Della Signoria. This top-rated public square provides an insightful glimpse into the city's identity. Next, discover Cathedral Of Santa Maria Del Fiore, a romantic church, promising a delightful encounter.

Continue your sightseeing with a visit to Ponte Vecchio, a wondrous historical landmark. When you’re done, don’t forget to make a stop at the top-rated Piazzale Michelangelo.

At the end of the day, you will drive to L'aquila, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of L'aquila's best restaurants.

Dive into a culinary adventure like no other in L'aquila by booking a table at FØRMA contemporary restaurant. This popular restaurant holds a Bib Gourmand award and offers an exceptional menu of contemporary and creative cuisine. If you're in the mood to try something new, consider DECA, another top spot with a mouthwatering menu.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Art Cafè L'aquila, a well-loved spot among locals and tourists.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 4

Day 4

  • L'Aquila
  • Naples
  • More

Drive 355 km, 4 hours 38 min

  • St Peter's Basilica
  • Sistine Chapel
  • Vatican Museums
  • More

Dive into day 4 of your remarkable road trip in Italy. Today you will explore Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Naples. You’ll stay here for 1 night.

Begin your sightseeing with St. Peter's Basilica. This iconic major basilica is one of the top attractions in the city. Proceed to Sistine Chapel, another must-visit attraction.

As you wander through the inviting streets of L'aquila, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Vatican Museums. This iconic art museum is a traveler-favorite.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Naples, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Get ready for an unforgettable culinary journey in Naples by reserving a table at Veritas. Renowned as a 1-star Michelin restaurant, it offers an exceptional campanian and contemporary menu. For a different taste experience, head to Il Comandante, recognized for its delicious creative and mediterranean dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit ARIA, a local favorite known for its delightful contemporary and modern cuisine in Naples. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for discerning contemporary and modern foodies seeking culinary excellence.

Following your dinner, dive into the local bar culture at Happening Cocktail Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Shanti Art Musik Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Gran Caffè Gambrinus provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Savor another day of unforgettable experiences in Italy!

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Day 5

Day 5

  • Naples
  • Rome
  • More

Drive 237 km, 3 hours 26 min

  • piazza del Plebiscito
  • Ovo Castle
  • Naples National Archaeological Museum
  • Cappella Sansevero
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Naples. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.

Get ready for an exciting day in Naples. Today’s sightseeing agenda includes a public square, a castle, and a museum. Begin your adventure at Piazza Del Plebiscito. This is a spectacular public square you should not miss. Another must-see is Ovo Castle, a notable castle in Naples.

When you’re ready for the next sight, head to Naples National Archaeological Museum. From there, take a leisurely stroll to Cappella Sansevero, another of the city’s locally renowned attractions.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Experience a taste of local culinary excellence while in Rome by securing a table at La Pergola. An esteemed 3-star Michelin restaurant, it features an exceptional mediterranean and contemporary menu. For an alternative taste experience, visit Il Pagliaccio, famous for its scrumptious creative and innovative dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Enoteca La Torre, a local favorite celebrated for its exquisite mediterranean and creative cuisine in Rome. Located in the heart of the city, this 2-star Michelin restaurant is an ideal pick for mediterranean and creative cuisine lovers seeking top-notch culinary experiences.

After enjoying a fulfilling meal, continue your evening at Sant' Eustachio Caffè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Yellowsquare Rome offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffè Portofino provides an excellent environment for a relaxed and enjoyable evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 6

Day 6

  • Rome - Departure day
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  • Altare della Patria
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Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Altare Della Patria, a breathtaking monument before you head out.

On your last day in Italy, take time to indulge in shopping at Rome’s popular marketplace, Trastevere. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

Have a fantastic dining experience at Hotel de Russie, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Taverna Italiana offers an enticing alternative with its varied menu.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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