12-Day Italy Self-Drive Road Trip With Itinerary from Naples traveling north to Viterbo, Florence, Siena, Rome, and Salerno

On day 2 of your road trip, you will have an entire day to explore Naples. You’ll stay in Naples for 1 night and discover all the best things to see and do in the area.

Set out on a day brimming with fun adventures, picturesque spots, and historic treasures. Start at the well-known Chiesa Del Gesù Nuovo, a photogenic church in Naples. Next, go to Cappella Sansevero.

After visiting Chiesa Del Gesù Nuovo and Cappella Sansevero, have a stroll along Naples's streets and take in the local charm. Continue your sightseeing by heading to Napoli Sotterranea Percorso Ufficiale. This standout cave system offers a unique experience. Cattedrale Di Santa Maria Assunta is another noteworthy attraction worthwhile a visit.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Discover the culinary delights of Naples by securing a reservation at Veritas. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of campanian and contemporary cuisine. For an alternative dining experience, try Il Comandante, renowned for its delicious creative and mediterranean dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to ARIA, a highly recommended local eatery celebrated for its mouthwatering contemporary and modern menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Keep the evening going at Archivio Storico - Cocktail Bar & Wonderfood, a great choice for enjoying the after-dinner hours with a drink. You could also go to Archeobar, which offers a similarly pleasant setting and great drinks. Another option is Babette Pub, which provides an inviting environment for unwinding after a busy day out.

Head back to your accommodation in Naples and get some rest in preparation for another magical day of your road trip in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Naples and Tivoli. When you’re not sightseeing, take time to relax at your selected hotel in Viterbo, where you’ll be staying for 1 night.

Today’s route brings fun adventures, scenic views, and picturesque spots. The first attraction of today is Castel Nuovo. This interesting castle is a picture-perfect place to see in Naples. Continue your discovery at Naples National Archaeological Museum, a photogenic museum with stories to tell.

As you stroll around Naples, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Hadrian's Villa. This intriguing archeological site offers a breathtaking encounter with Naples. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Naples.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Viterbo. Viterbo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Viterbo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Get a good night's sleep and look forward to another great day on the road in Italy!

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Orvieto. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Set out on a day brimming with fun adventures, romantic experiences, and breathtaking views. Start at the captivating Orvieto Cathedral, an inviting church in Viterbo. Next, go to Museo Dell'opera Del Duomo.

After visiting Orvieto Cathedral and Museo Dell'opera Del Duomo, have a stroll along Viterbo's streets and take in the local charm. Continue your sightseeing by heading to Orvieto Underground. This standout cave system offers a unique experience. Well Of St. Patrick is another noteworthy attraction worthwhile a visit.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a memorable dining experience in Florence by booking a table at Enoteca Pinchiorri, renowned as a 3-star Michelin restaurant presenting an exceptional italian contemporary menu. For a different culinary experience in Florence, Santa Elisabetta shines as one of the top destinations, known for its delicious creative and mediterranean cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Gucci Osteria da Massimo Bottura is known as a top local spot for its delicious italian contemporary and international cuisine in Florence. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Continue your evening by exploring the vibrant nightlife scene at Manifattura, a prime destination for a thrilling night out. Also, don’t forget to check out Se·sto On Arno Rooftop Bar, a bar that offers unique local touches. Likewise, Il Vinile provides an excellent alternative for a fun evening.

Raise your glass to another unforgettable day in Italy!

Day 5 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

At the top of the list of things to do today is to explore Oltrarno, a neighborhood that captures the true essence of Florence. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Prepare for a day full of fun adventures, romantic experiences, and breathtaking views. When you’re ready, kick off your sightseeing adventure at Ponte Vecchio. This world-famous historical landmark is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Piazza Della Signoria, one of the city’s best highlights.

Next, check out Uffizi Gallery, one of the most impressive places to see in Florence. This art gallery is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazzale Michelangelo. Wander around and soak in the enchanting atmosphere this observation deck offers.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Ditta Artigianale, a highly-rated dining destination in Florence. If you're eager to try something different, consider Trattoria Da Burde, another top spot with a tantalizing menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence and Pisa. In the evening, you’ll end up in Siena, where you will stay for 1 night.

Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await! Cathedral Of Santa Maria Del Fiore is the perfect place to start. This church is one of the most astonishing places to visit in Florence. Next, head to Galleria Dell'accademia, a well-known art gallery, known for its photogenic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Leaning Tower Of Pisa. This masterful monument is a highly recommended experience. Nearby, you'll also find Piazza Del Duomo, Pisa. Visit these for an interesting touch to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Enoteca I Terzi, a highly-rated dining destination in Siena. If you're eager to try something different, consider Ristorante Tar-Tufo, another top spot with a tantalizing menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Siena this evening.

Cap off your dinner by heading to Meet Life Cafè, ideal for a leisurely evening with a drink in hand. Maudit Pub is another bar that offers an enjoyable setting. Similarly, Bar Impero Siena is also a popular place to go on a night out, perfect for relaxing and socializing.

Say good night to Siena and look forward to another great day of your road trip in Italy!

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 3 nights.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Siena allows for both. Start by heading to Sistine Chapel. This famous chapel provides an insightful glimpse into the city's identity.

Continue your sightseeing with a visit to Saint Peter's Square, a locally renowned square. When you’re done, don’t forget to make a stop at the iconic Vatican Museums.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Experience a symphony of flavors at La Pergola in Rome by securing a reservation in advance. Renowned for its 3-star Michelin distinction, La Pergola delights its guests with its exceptional variety of meals showcasing delicious mediterranean and contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Il Pagliaccio, acclaimed for its delectable creative and innovative specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Enoteca La Torre, a top-rated restaurant known for its outstanding menu. Known as a top-rated 2-star Michelin establishment, it's a top choice for mediterranean and creative cuisine in the city.

Let the evening flow smoothly from dinner to drinks at La Botticella Of Poggi Giovanni, a top-rated bar in the area. For other recommendations, Almalu Trastevere provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Viminale Di Pepi Maurilio offers a memorable night with diverse drink options and excellent service.

Celebrate another amazing day of your road trip adventure in Italy!

Day 8 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

A visit to Trastevere in Rome is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights. Don’t forget to check out Monti as well, a neighborhood that adds another layer to your exploration.

Brace yourself for today’s incredible lineup of attractions in Rome, featuring fun adventures, scenic views, and photo-friendly spots. Start at Altare Della Patria, a popular monument in the city. Then, head to Roman Forum and soak in the ambiance of this UNESCO world heritage-designated archeological site.

There are many interesting places to see in Rome, and when you are ready for more, go to Colosseum. This is one of the city’s most world-famous breathtaking spots of interest.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Continue your evening by exploring the vibrant nightlife scene at Sant' Eustachio Caffè, a prime destination for a thrilling night out. Also, don’t forget to check out Yellowsquare Rome, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Day 9 of your road trip across Italy promises a magnificent time exploring Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

One of the most iconic places you can visit today in Rome is Via del Corso. Allow yourself some time to explore this street and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Get ready to discover some of the most iconic wonders in Rome, including a castle, a public square, and a monument. Start your day at Castel Sant'angelo. This romantic castle is an impressive place to see in Rome. Then, wander over to Piazza Navona. If symbolic sites excite you, this public square will be right up your alley. Nearby, you’ll also find Pantheon. This heritage-rich monument is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Del Popolo is an astonishing spot in the city that will captivate you with its unique charm.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delightful dinner at Hotel de Russie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Taverna Italiana? It's another excellent option with a diverse menu. Consider reserving a table at The Parrot Bar as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

Cap off your dinner by heading to The Apartment Bar Roma, ideal for a leisurely evening with a drink in hand. Hotel Hassler Roma is another bar that offers an enjoyable setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Experience an unparalleled adventure on day 10 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Salerno. You will spend 1 night here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Rome today. One of the most globally renowned attractions included on the itinerary is Trevi Fountain. This enchanting monument will help you start your sightseeing on top. Then, take a leisurely stroll to Piazza Di Spagna and learn what makes this enchanting public square unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the spectacular Spanish Steps. After exploring the public square, head to Villa Borghese. This top-rated park is a highlight in Rome.

At the end of the day, you will drive to Salerno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Salerno, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Set out on a gastronomic journey in Salerno by reserving a table at Re Maurì. Renowned for its 1-star Michelin recognition, this restaurant presents an outstanding menu of creative cuisine. Looking for something different? L'Unico Drink & Food Salerno offers a tantalizing alternative with its diverse menu. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Salerno.

Keep the excitement of the evening going by visiting a bar or two. Hilton Bar E Gastronomia is an excellent place to start. You could also check out The Black Monday Speakeasy Tbm, offering a different kind of charm. A last recommendation for the day is Dòmo I' Vinaino Wine Bar - Enogastronomia. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, Paestum, Amalfi, and Pompei. When you’re not sightseeing, take time to relax at your selected hotel in Naples, where you’ll be staying for 1 night.

Prepare for a day full of family-friendly attractions, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Archaeological Park Of Paestum. This well-known archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Amalfi Coast, one of the hamlet’s best highlights.

Next, check out Archaeological Park Of Pompeii, one of the most well-known places to see in Salerno. This archeological site is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Teatro Grande. Wander around and soak in the historic atmosphere this archeological site offers.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Enjoy a delicious meal at Opera Restaurant, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Trattoria San Ferdinando, another top spot with a mouthwatering menu. You might also want to secure a reservation at Anonymous Trattoria Gourmet. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

After enjoying a fulfilling meal, continue your evening at Gran Caffè Cimmino, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Flanagan's Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Napoli provides an excellent environment for a relaxed and enjoyable evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.