12-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling south to Trikala, Arachova, Athens, Nafplio, and Patras
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Explore the best of Greece on a 12-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Thessaloniki, Kastraki, Kalambaka, Trikala, Arachova, Delphi, Athens, Lavreotiki, Nafplio, Mykines, Lighourio, Patras, and Vergina. This road trip itinerary in Greece seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki, 1 night in Trikala, 1 night in Arachova, 3 nights in Athens, 2 nights in Nafplio, and 1 night in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Acropolis Museum, learn more about the unique White Tower Of Thessaloniki, and immerse yourself in the vibrant atmosphere of Aristotelous Square.
As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Trikala, Arachova, Delphi, Athens, Lavreotiki, Nafplio, Mykines, Lighourio, Patras, and Vergina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.
Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!
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Day 1
- Thessaloniki - Arrival day
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- Ladadika
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Welcome to Thessaloniki, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Thessaloniki's charm before embarking on the next leg of your journey.
Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.
Savor the flavors at Kitchen Bar, a top pick for dinner tonight. Alternatively, The Greek beckons with its unique menu offerings. Also, consider Phanós. With its consistent customer satisfaction, it’s an excellent option for dining in Thessaloniki tonight.
To truly maximize your evening out, consider visiting Beetle Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Vogatsikou 3, another bar with an inviting ambiance. Similarly, Souel also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Raise a toast to the start of your 12-day road trip in Greece!
Day 2
- Thessaloniki
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Drive 5 km, 48 min
- White Tower of Thessaloniki
- Arch of Galerius
- Agias Sofias Square
- Aristotelous Square
- Tsimiski Street
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On day 2 of your road trip, you will have an entire day to explore Thessaloniki. You’ll stay in Thessaloniki for 1 night and discover all the best things to see and do in the area.
Make sure to visit Tsimiski Street, a popular street in Thessaloniki. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.
Get ready for a day filled with family-friendly attractions, breathtaking views, and picturesque spots in the charming city of Thessaloniki. Your adventure starts at White Tower Of Thessaloniki, a spectacular local hot spot. Another notable attraction to explore is Arch Of Galerius And Rotunda. This interesting monument is known for its stunning appeal.
After soaking in the highlights of these sights, take some time to wander Thessaloniki's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Agias Sofias Square. This eye-catching public square offers a fascinating experience that many visitors find memorable. Aristotelous Square is also worth visiting.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Enjoy a delicious meal at Mamalouka, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider Clochard, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Castra- All Day Terrace Bar, known for its inviting atmosphere. Barbaben - Bar/ba/ben is another great option if you’re looking for a place to get the night started. Similarly, Apallou provides a great setting to enjoy the night away.
Get a good night's sleep and look forward to another great day on the road in Greece!
Day 3
- Thessaloniki
- Trikala
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Drive 259 km, 4 hours 6 min
- Meteora
- Holy Monastery of Rousanos - Saint Barbara
- Main Observation Deck of Meteora
- Natural History Museum of Meteora and Mushroom Museum
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Embark on another extraordinary experience on day 3 of your road trip in Greece. Today, you will make 2 stops and experience some of the highlights of Kastraki and Kalambaka. At the end of the day, you will enjoy the comforts of a top-rated hotel in Trikala, which will be your home away from home for 1 night.
Today’s agenda in Thessaloniki includes a monastery, an observation deck, and a museum. Meteora is must-visit monastery and a great starting point for the day. Next, continue your journey to Moni Rousanou, an increasingly popular monastery, located just a leisurely stroll away. Next, head to Main Observation Deck Of Meteora, an eye-catching observation deck, also available for your discovery today.
At the end of the day, you will drive to Trikala, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
Indulge in a memorable dining experience at one of Trikala's most popular restaurants, and connect with friendly locals for an authentic adventure.
Have a fantastic dining experience at ALVEO, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trikala Fortress offers an enticing alternative with its varied menu. Additionally, Palia Istoria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Trikala.
After enjoying a fulfilling meal, continue your evening at Soyita Art Cafe, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Factory Café offers a welcoming atmosphere for easing into the nightlife. Similarly, The Love Shake provides an excellent environment for a relaxed and enjoyable evening.
Celebrate another amazing day of your road trip adventure in Greece!
Day 4
- Trikala
- Arachova
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Drive 247 km, 3 hours 56 min
- Monastery of the Holy Trinity at Meteora
- Monastery of St Stephan
- The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
- Monastery of Varlaam
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On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Kalambaka and Kastraki. When you’re not sightseeing, take time to relax at your selected hotel in Arachova, where you’ll be staying for 1 night.
Discover a day packed with fun adventures, scenic views, and photo-friendly spots in Trikala. Begin your sightseeing with Monastery Of The Holy Trinity At Meteora. This frequently visited monastery is one of the top attractions in the town. Proceed to Holy Monastery Of Saint Stephan, another must-visit attraction.
As you wander through the inviting streets of Trikala, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This up-and-coming monastery is a traveler-favorite. Not far away, you’ll find Monastery Of Varlaam, another key site on your sightseeing itinerary.
When you’re done exploring for the day, you’ll drive to your hotel in Arachova. Check in and spend some time relaxing before you head out to tour the village.
As you explore more of Arachova, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Head back to your accommodation in Arachova and get some rest in preparation for another magical day of your road trip in Greece!
Day 5
- Arachova
- Athens
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Drive 195 km, 3 hours 3 min
- Ancient Stadium of Delphi
- Temple of Apollo
- Delphi Archaeological Museum
- Castalian Spring
- Tholos of Delphi
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Experience an unparalleled adventure on day 5 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Delphi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Athens. You will spend 3 nights here for some well-deserved relaxation.
Arachova is home to plenty of attractions that offer fun adventures, scenic views, and photo-friendly spots! Start at Ancient Stadium Of Delphi, an underrated archeological site that is worthwhile a visit in the village. Nearby, you’ll find Temple Of Apollo In Delphi, enchanting visitors with its breathtaking appeal. Continue your exploration at Delphi Archaeological Museum. This museum is one of the village’s most well-known spots.
Enjoy the freedom of exploring Arachova at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Castalian Spring. After exploring the archeological site, head to the locally appreciated Tholos Of Delphi.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Athens. Athens offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Athens. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Savor the flavors at Zampano, a top pick for dinner tonight. Alternatively, Rosalia beckons with its unique menu offerings. Also, consider NJV Athens Plaza. With its consistent customer satisfaction, it’s an excellent option for dining in Athens tonight.
After savoring a delicious meal, step into the vibrant nightlife at Mayros Gatos, where the evening is just getting started. In the same way, Kuko's The Bar offers a unique charm perfect for experiencing the local bar scene in Athens. Revolt Street Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Relax and reminisce about your day in Greece and look forward to more memorable moments to come!
Day 6
- Athens
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Drive 4 km, 1 hour 2 min
- Parthenon
- Acropolis of Athens
- Acropolis Museum
- Plaka
- Monastiraki
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Day 6 of your road trip across Greece promises a magnificent time exploring Athens. You have 2 nights left in Athens. Take the opportunity to experience more of the best attractions and activities in the city.
A top thing to do today is to explore Plaka, a must-see neighborhood in Athens. It's the perfect starting point for touring the top attractions in the area. You can also visit Monastiraki, an ideal neighborhood for continued sightseeing.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Athens allows for both. Start by heading to Parthenon. This top-rated archeological site provides an insightful glimpse into the city's identity. Next, discover Acropolis Of Athens, a picture-perfect archeological site, promising a delightful encounter.
Continue your sightseeing with a visit to Acropolis Museum, an astonishing museum.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Athens, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delightful dinner at Harvest Coffee & Wine, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try 42 Barstronomy Athens? It's another excellent option with a diverse menu. Consider reserving a table at O Babas as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Athens.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Tiki Bar Athens stands out as an excellent choice for a post-dinner cocktail. Alternatively, Brettos offers an ideal atmosphere to enjoy the pleasures of the night. Luxus Bar Bistro is also a great option that provides a perfect setting for a relaxing evening.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.
Day 7
- Athens
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Drive 153 km, 2 hours 25 min
- Temple of Poseidon
- Archaeological Site of Sounion
- Archaeological Museum of Lavrion
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Wake up to day 7 of your extraordinary road trip in Greece. With 1 night left in Athens, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Today’s itinerary in Athens covers several incredible sights, including an archeological site and a museum. Start your adventure at Temple Of Poseidon At Cape Sounion. This well-known archeological site is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the history-steeped wonders of Archaeological Site Of Sounion, a must-see archeological site in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Archaeological Museum Of Lavrion. This curiosity-inducing museum offers an enriching experience. These sights offer a fulfilling end to a perfect day.
When you’re done exploring for the day, you’ll return to Athens and your accommodation.
After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.
Enjoy a lovely dining experience at Cookoovaya, a popular restaurant in Athens. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Athens at Karamanlidika, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Estiatorio Auli. It’s yet another ideal choice to enhance your time in Athens tonight.
To truly maximize your evening out, consider visiting Kazu Cafe-bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Upupa Epops - The Bar, another bar with an inviting ambiance. Similarly, Gazarte also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Raise your glass to another unforgettable day in Greece!
Day 8
- Athens
- Nafplio
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Drive 147 km, 3 hours 49 min
- Nafplio Port
- Archaeological Museum of Nafplion
- Church of Saint Spyridon
- Akronauplía
- Palamidi
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On day 8 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Nafplio. In the evening, you’ll end up in Nafplio, where you will stay for 2 nights.
Get ready to discover some of the most iconic wonders in Athens, including a marina, a museum, a church, a castle and much more! Start your day at Nafplio Port. This romantic marina is a curiosity-inducing place to see in Athens. Then, wander over to Archaeological Museum Of Nafplion. If eye-catching sites excite you, this museum will be right up your alley. Nearby, you’ll also find Church Of Saint Spyridon. This respected church is a favorite among visitors.
Athens offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Fortress Of Akronauplía is a worthwhile spot in the town that will captivate you with its unique charm. When you’re done at the castle, don’t forget to check out the visually striking Palamidi. Take a moment to appreciate the fascinating details of this locally renowned castle.
At the end of the day, you will drive to Nafplio, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Nafplio. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delightful dinner at Arapakos, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try The Corner of Kavalaris? It's another excellent option with a diverse menu. Consider reserving a table at To Omorfo Tavernaki as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Nafplio.
Explore the vibrant nightlife at Jukebox Espresso Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Allotino Coffee & Bar for a great selection of flavorful drinks and a charming setting.
Take some time to reflect on your day and savor another beautiful night in Greece.
Day 9
- Nafplio
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Drive 98 km, 2 hours 4 min
- Archeological Museum of Mycenae
- Mycenae
- Treasury of Atreus" or "Tomb of Agamemnon
- Archaeological Site of the Sanctuary of Asclepius at Epidaurus
- Ancient Theatre at the Asclepieion of Epidaurus
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On day 9 of your road trip in Greece, you’ll start and end your day in Nafplio, but spend the day exploring what’s beyond the town. Since you will return to Nafplio for 1 night more, there’s no need to rush. Experience Mykines and Lighourio to the fullest today with this curated day itinerary!
Get ready for an exciting day in Nafplio. Today’s sightseeing agenda includes a museum and an archeological site. Begin your adventure at Archeological Museum Of Mycenae. This is an up-and-coming museum you should not miss. Another must-see is Mycenae, a locally renowned archeological site in Nafplio.
When you’re ready for the next sight, head to "treasury Of Atreus" Or "tomb Of Agamemnon". From there, take a leisurely stroll to Archaeological Site Of The Sanctuary Of Asclepius At Epidaurus, another of the village’s locally appreciated attractions. We recommend continuing your self-guided tour at Ancient Theatre At The Asclepieion Of Epidaurus, a picture-perfect place of interest in the village.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Nafplio.
Indulge in a memorable dining experience at one of Nafplio's most popular restaurants, and connect with friendly locals for an authentic adventure.
Make sure to reserve a table at ΞENON Café · Bistro, an iconic dining spot in Nafplio. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of O Vasilis taverna, a popular restaurant in Nafplio. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Blublanc, a hidden gem nestled in Nafplio. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Celebrate another amazing day of your road trip adventure in Greece!
Day 10
- Nafplio
- Patras
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Drive 188 km, 2 hours 46 min
- Patras' South Park - Notio Parko Patras
- Church of Agios Andreas
- Patras Castle
- St Nicholas Stairway
- King George Ι Square (Patras)
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Dive into day 10 of your remarkable road trip in Greece. Today you will explore Patras, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Patras. You’ll stay here for 1 night.
Immerse yourself in Nafplio’s rich culture with today's sightseeing itinerary. Start your journey at Patras' South Park - Notio Parko Patras. This stunning park is sure to ignite your curiosity. Next, dive into the picture-perfect features of Holy Church Of Saint Andrew, a must-visit church in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Patras Castle, an up-and-coming castle. For a change of scene, check out St. Nicholas Stairway, known for its romantic features. We also recommend visiting King George I Square (patras). This public square is a must for anyone looking to experience the city to the fullest.
When you’re done exploring for the day, you’ll drive to your hotel in Patras. Check in and spend some time relaxing before you head out to tour the city.
As dinnertime approaches, it's time to head out for a bite to eat in Patras. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Dine in style at Tag, a top recommendation for dinner tonight. Or, for a change of pace, Bianco boasts a menu that's sure to impress. Also, be sure to check out Carousello. Known as a local hotspot, it’s a great choice for tonight in Patras.
To truly maximize your evening out, consider visiting Sofita after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Charama Therino, another bar with an inviting ambiance. Similarly, Notos also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Savor another day of unforgettable experiences in Greece!
Day 11
- Patras
- Thessaloniki
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Drive 484 km, 5 hours 7 min
- Polycentric Museum of Aigai (Aegae) - Main Building
- Museum of the Royal Tombs at Aigai (Aegae)
- Haliacmon Dam - Artificial Lake at Saint Barbara of Veria
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Embark on another extraordinary experience on day 11 of your road trip in Greece. Today, you will make 1 stop and experience some of the highlights of Vergina. At the end of the day, you will enjoy the comforts of a top-rated hotel in Thessaloniki, which will be your home away from home for 1 night.
Enjoy the perfect balance of relaxation and exploration in Patras today. One of the most often recommended attractions included on the itinerary is Polycentric Museum Of Aigai (aegae) - Main Building. This UNESCO world heritage-designated museum will help you start your sightseeing on top. Then, take a leisurely stroll to Museum Of The Royal Tombs At Aigai (aegae) and learn what makes this UNESCO world heritage-listed museum unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the beloved Haliacmon Dam - Artificial Lake At Saint Barbara Of Veria.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.
Treat yourself to a wonderful meal at Enoches Bar, a top-rated dining spot in Thessaloniki. If you're in the mood for something new, try O Loytros, another premier location with a delectable menu. You might also want to book a table at rOOTS. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Thessaloniki.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Peiratis Cafe-bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, In Rock Cafe Bar offers an ideal atmosphere to enjoy the pleasures of the night. Tribeca is also a great option that provides a perfect setting for a relaxing evening.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.
Day 12
- Thessaloniki - Departure day
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- The Umbrellas by Zongolopoulos
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Day 12 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at The Umbrellas Sculpture By Zogolopoulos. This captivating art installation is a popular place to see in the city.
Maximize your last day in Greece and go on a shopping spree in Thessaloniki’s shopping center, the lively Tsimiski Street. Browse for souvenirs to remind you of your wonderful journey in Greece. Discover boutiques with stylish fashion choices to upgrade your wardrobe.
Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.
If you're in the mood to try something new, consider Agora Ouzeri, another top spot with a mouthwatering menu.
You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!
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