4-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Patras

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Explore the best of Greece on a 4-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Ioannina, Perama, Neo Bizani, Patras, Antirio, and Mesolongi. This road trip itinerary in Greece seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Ioannina and 1 night in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Ioannina Castle and Moyseio Ellinikis Istorias Payloy Vrelli are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Cave Of Perama, learn more about the unique Charilaos Trikoupis Rio - Antirrio Bridge, and immerse yourself in the vibrant atmosphere of Holy Church Of Saint Andrew.

As you hit the open road and drive through Ioannina, Perama, Neo Bizani, Patras, Antirio, and Mesolongi, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ioannina Castle
Cave of PeramaMuseum "Arslan Pasha"Ich Kale Acropolis of IoanninaSilversmithing MuseumVrellis Greek History Museum (Wax Museum)
King George Ι Square (Patras)Church of Agios AndreasPatras' South Park - Notio Parko PatrasRion-Antirion BridgeGarden of Heroes
The Clock Tower of Ioannina

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Day 1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Say hello to Ioannina! Your exciting road trip through Greece is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Ioannina for 1 night before you continue your adventure!

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Ioannina. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at To Dodeka Cafe Bar, a top-rated dining destination in Ioannina. If you're in the mood to try something new, consider Mustagogia, another top spot with a mouthwatering menu. You might also want to secure a reservation at Accademia Del Panino. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Ioannina this evening.

Continue your evening by exploring the vibrant nightlife scene at ⚜ V E D E M A ⚜, a prime destination for a thrilling night out. Also, don’t forget to check out Hogwarts Tales And Spirits, a bar that offers unique local touches. Likewise, Chevalier provides an excellent alternative for a fun evening.

Raise a toast to the start of your 4-day road trip in Greece!

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Day 2

Day 2

  • Ioannina
  • Patras
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Drive 230 km, 3 hours 9 min

  • Cave of Perama
  • Museum "Arslan Pasha"
  • Ich Kale Acropolis of Ioannina
  • Silversmithing Museum
  • Vrellis Greek History Museum (Wax Museum)
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Embark on another extraordinary experience on day 2 of your road trip in Greece. Today, you will make 3 stops and experience some of the highlights of Perama, Ioannina, and Neo Bizani. At the end of the day, you will enjoy the comforts of a top-rated hotel in Patras, which will be your home away from home for 1 night.

Brace yourself for today’s incredible lineup of attractions in Ioannina, featuring family-friendly attractions, natural wonders, and breathtaking views. Start at Cave Of Perama, a frequently visited cave in the town.

There are many interesting places to see in Ioannina, and when you are ready for more, go to Ic Kale Acropolis Of Ioannina. This is one of the town’s most often recommended historic spots of interest. After exploring the archeological site, visit the worthwhile Silversmithing Museum Of Ioannina. Not far away, you'll also find Moyseio Ellinikis Istorias Payloy Vrelli. This museum is a standout highlight in Ioannina.

When you’re done exploring for the day, you’ll drive to your hotel in Patras. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Patras. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Tag, a top-rated dining destination in Patras. If you're in the mood to try something new, consider Bianco, another top spot with a mouthwatering menu. You might also want to secure a reservation at Carousello. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Patras this evening.

After savoring a delicious meal, step into the vibrant nightlife at Sofita, where the evening is just getting started. In the same way, Charama Therino offers a unique charm perfect for experiencing the local bar scene in Patras. Notos is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.

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Day 3

Day 3

  • Patras
  • Ioannina
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Drive 228 km, 3 hours 5 min

  • King George Ι Square (Patras)
  • Church of Agios Andreas
  • Patras' South Park - Notio Parko Patras
  • Rion-Antirion Bridge
  • Garden of Heroes
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Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Patras, Antirio, and Mesolongi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ioannina. You will spend 1 night here for some well-deserved relaxation.

Set out on a day brimming with fun adventures, romantic experiences, and scenic views. Start at the intriguing King George I Square (patras), an enchanting public square in Patras. Next, go to Holy Church Of Saint Andrew.

After visiting King George I Square (patras) and Holy Church Of Saint Andrew, have a stroll along Patras's streets and take in the local charm. Continue your sightseeing by heading to Patras' South Park - Notio Parko Patras. This idyllic park offers a unique experience. Charilaos Trikoupis Rio - Antirrio Bridge is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Garden Of Heroes, one of the most culturally significant places to visit in Patras.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Ioannina, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Spitaki me thea, a top-rated dining spot in Ioannina. If you're in the mood for something new, try Frontzoy Politeia - Frontzu Politia Restaurant, another premier location with a delectable menu. You might also want to book a table at Papi Cafe Bistro. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Ioannina.

Keep the excitement of the evening going by visiting a bar or two. Scala is an excellent place to start. You could also check out Route 66 Bar, offering a different kind of charm. A last recommendation for the day is Palia Agora. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 4

Day 4

  • Ioannina - Departure day
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  • The Clock Tower of Ioannina
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Day 4 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Clock Tower Of Ioannina, a picture-perfect monument before you head out.

As your final day in Greece unfolds, enjoy a last-minute shopping spree in Ioannina's best shopping area, Epirus Street. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Greece. Browse through boutiques to find unique and stylish fashion pieces to take home. When you need a break, visit a cafe and relax with a cup of coffee or tea.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

Treat yourself to a delicious dinner at PRESVEIA Restaurant Meze, an excellent option for tonight's dining. Looking for something different? Frontzu Politia - Hotel offers a tantalizing alternative with its diverse menu. And don’t miss Equus.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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