6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
Photo of tourist dressed in the old town square of Prague, Czech Republic.
Photo of aerial view of old town Square in Prague, Czech Republic.
Photo of architecture and landmark of Prague, Czech Republic.
Photo of gulls over Prague chimes and Tynsky cathedral at summer day, Czech Republic.
Photo of scenic view of the old town pier architecture and Charles Bridge over Vltava river in Prague, Czech Republic.
Photo of Prague beautiful panoramic sunny aerial drone view above Prague Old Town, Czech Republic.
Photo of Prague Old Town Square Czech Republic, sunrise city skyline at Astronomical Clock Tower.
Photo of woman enjoys the elevated view over the city of Prague, Czech Republic, on a sunny autumn day.
Photo of Prague street, Czech Republic.
Photo of Prague, Czech Republic. Charles Bridge and Old Town Tower at sunrise.
Historic castle of Cesky Krumlov and town in Czech Republic
Czech Krumlov, (Cesky Krumlov), Czech Republic. Wooden bridge over river Vltava. Vintage picturesque old town with colorful houses and chapel of church. Rose flowers on bank. Sunny summer day.
View of historical centre of Cesky Krumlov town on Vltava riverbank on autumn day overlooking medieval Castle, Czech Republic. View of old town of Cesky Krumlov, South Bohemia, Czech Republic.
Panoramic view of Cesky Krumlov with St Vitus church in the middle of historical city centre. Cesky Krumlov, Southern Bohemia, Czech Republic.
Photo of amazing view of the old town and Cathedral of St. Peter and Paul in Brno, Czech Republic.
Photo of building in Denis Gardens in the center of Brno city, Czech Republic.
Photo of old town street, The Church of Jan Amos Comenius Red Church and tram in Brno.
Photo of Parnas Fountain on Zerny trh square in the old town of Brno, Czech Republic.
Photo of beautiful old castle Veveri. Landscape with water on the Brno dam during summer holidays, Czech Republic.
Photo of old town of Brno as seen from the town hall tower, Czech Republic.
Photo of landscape with water on the Brno dam during summer holidays on a sunny day, Czech Republic.
Photo of top view of Brno downtown, Czech Republic.
Photo of beautiful old castle Spilberk, City of Brno, Czech Republic.
Photo of cathedral of Saints Peter and Paul. Beautiful old architecture and a popular tourist destination, Brno, Czech Republic.
Photo of Slavkov Castle Brno, Czech Republic.
Photo of aerial view of Dam in Brno, Czech Republic.
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Experience the freedom of the open road in the Czech Republic as you embark on an unforgettable 6-day road trip! This experience caters to every traveler, featuring destinations like Prague, Kutná Hora, Český Krumlov, Telč, Brno, Nové Dvory, Sloup, and Litomyšl.

This perfectly planned road trip itinerary in the Czech Republic takes you through some of the best places to see in the country. You will spend 3 nights in Prague, 1 night in Český Krumlov, and 1 night in Brno. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique Powder Tower, and immerse yourself in the vibrant atmosphere of Špilberk Castle.

As you hit the open road and drive through Prague, Kutná Hora, Český Krumlov, Telč, Brno, Nové Dvory, Sloup, and Litomyšl, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Charles Bridge
Prague CastlePowder TowerSedlec OssuarySt Barbara's CathedralMalá Strana
The Castle GardenČeský Krumlov Castle TowerLazebnický mostHouse of MirrorsEgon Schiele Art CentrumMoldavite Museum
Telč châteauVilla Tugendhatcathedral of St. Peter and PaulŠpilberk Castle
Macocha AbyssPunkva CavesSloupsko-šošůvské jeskyněMonastery gardens
Old Town Square

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Day 1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay in Prague for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at U Tellerů, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Restaurace U Bansethů, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eska Restaurant and Bakery. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

To truly maximize your evening out, consider visiting Anonymous Shrink's Office after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar No. 7 - Prague, another bar with an inviting ambiance. Similarly, Kontakt Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 6-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 178 km, 3 hours 5 min

  • Prague Castle
  • Powder Tower
  • Sedlec Ossuary
  • St Barbara's Cathedral
  • Malá Strana
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Wake up to day 2 of your extraordinary road trip in the Czech Republic. With 1 night left in Prague, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Malá Strana is one of the highlights of today. Take your time exploring this iconic neighborhood in Prague, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Today's adventure in Prague promises more breathtaking discoveries and enriching experiences! Begin at Prague Castle. This UNESCO world heritage-listed castle is a highlight of any visit in the city. Then, enjoy Powder Tower, another respected attraction that never fails to captivate visitors. Next, head over to Sedlec Ossuary, one of the city’s most well-known attractions, known for its photogenic features.

If you’re looking for more, spend time soaking in the atmosphere of St Barbara's Cathedral. This history-steeped church is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

When you’re done exploring for the day, you’ll return to Prague and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Brasileiro Restaurant, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurant Meat Beer, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurace Století, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Bowla Bar, known for its lively atmosphere. The Saints is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Beergeek Bar offers an excellent atmosphere for those looking to amp up the evening.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day 3

Day 3

  • Prague
  • Český Krumlov
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Drive 179 km, 2 hours 40 min

  • The Castle Garden
  • Český Krumlov Castle Tower
  • Lazebnický most
  • House of Mirrors
  • Egon Schiele Art Centrum
  • Moldavite Museum
  • More

On day 3 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 1 destination, Český Krumlov. When you’re not sightseeing, take time to relax at your selected hotel in Český Krumlov, where you’ll be staying for 1 night.

Set out on a day brimming with fun adventures, romantic experiences, and scenic views. Start at the worthwhile The Castle Garden, an UNESCO world heritage-listed castle in Prague. Next, go to Český Krumlov Castle Tower.

House Of Mirrors is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Egon Schiele Art Centrum, one of the most photogenic places to visit in Prague. If you still have some time left for sightseeing, we also recommend stopping by Moldavite Museum.

At the end of the day, you will drive to Český Krumlov, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Český Krumlov. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Say good night to Český Krumlov and look forward to another great day of your road trip in the Czech Republic!

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Day 4

Day 4

  • Český Krumlov
  • Brno
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Drive 246 km, 3 hours 59 min

  • Telč château
  • Villa Tugendhat
  • cathedral of St. Peter and Paul
  • Špilberk Castle
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Embark on another extraordinary experience on day 4 of your road trip in the Czech Republic. Today, you will make 2 stops and experience some of the highlights of Telč and Brno. At the end of the day, you will enjoy the comforts of a top-rated hotel in Brno, which will be your home away from home for 1 night.

Get ready for an exciting day in Český Krumlov. Today’s sightseeing agenda includes a castle, a museum, and a church. Begin your adventure at Telč Château. This is a locally appreciated castle you should not miss. Another must-see is Villa Tugendhat, an underrated museum in Český Krumlov.

When you’re ready for the next sight, head to Cathedral Of St. Peter And Paul. From there, take a leisurely stroll to Špilberk Castle, another of the town’s notable attractions.

When you’re done exploring for the day, you’ll drive to your hotel in Brno. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Brno, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at U Štíra, a top-rated dining destination in Brno. If you're in the mood to try something new, consider Bistro Franz, another top spot with a mouthwatering menu. You might also want to secure a reservation at Noem Arch Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brno this evening.

To truly maximize your evening out, consider visiting Bar Naproti after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Super Panda Circus, another bar with an inviting ambiance. Similarly, Výčep Na Stojáka also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in the Czech Republic.

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Day 5

Day 5

  • Brno
  • Prague
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Drive 294 km, 4 hours 36 min

  • Macocha Abyss
  • Punkva Caves
  • Sloupsko-šošůvské jeskyně
  • Monastery gardens
  • More

Dive into day 5 of your remarkable road trip in the Czech Republic. Today you will explore Nové Dvory, Sloup, and Litomyšl, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Prague. You’ll stay here for 1 night.

Today’s route brings family-friendly attractions, natural wonders, and breathtaking views. The first attraction of today is Macocha Abyss. This intriguing cave is an instagrammable place to see in Brno. Continue your discovery at Punkva Caves, a majestic cave system with stories to tell.

As you stroll around Brno, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Sloupsko-šošůvské Jeskyně. This intriguing cave system offers a visually striking encounter with Brno. Next, make your way to Monastery Gardens In Litomyšl to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Brno.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Prague. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at BeBop Bar, a top recommendation for dinner tonight. Or, for a change of pace, Café restaurant Palanda boasts a menu that's sure to impress. Also, be sure to check out Restaurace Tiskárna. Known as a local hotspot, it’s a great choice for tonight in Prague.

Explore the vibrant nightlife at Uhříněveský Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Boothill Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Manesova Bar And Books is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day 6

Day 6

  • Prague - Departure day
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  • Old Town Square
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Day 6 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Old Town Square. This iconic public square is a popular place to see in the city.

On your last day in the Czech Republic, take time to indulge in shopping at Prague’s popular marketplace, Wenceslas Square. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

If you're in the mood to try something new, consider U Fleků, another top spot with a mouthwatering menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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