6-Day France Road Trip from Grenoble to Lyon, and Nimes

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Escape the ordinary with this exciting 6-day road trip through France. Explore the diverse landscapes and local cultures of Grenoble, Lyon, Caluire-et-Cuire, Vaulx-en-velin, Avignon, Nimes, Arles, and Les Baux-de-Provence. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in France takes you through some of the best places to see in the country. You will spend 2 nights in Grenoble, 2 nights in Lyon, and 1 night in Nimes. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in France. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Grenoble, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover France on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in France. Parc De La Tête D'or and Palais Des Papes are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Grenoble, Lyon, Caluire-et-Cuire, Vaulx-en-velin, Avignon, Nimes, Arles, and Les Baux-de-Provence, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of France. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in France.

Throughout your road trip in France, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in France.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in France fill up quickly, so book your spot early. Select a date and start planning your road trip in France today!

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Day 1

Day 1 – Grenoble - arrival day

  • Grenoble - Arrival day
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  • Parc Paul Mistral
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Welcome to Grenoble, the perfect starting point for your road trip in France! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Grenoble's charm before embarking on the next leg of your journey.

Grenoble is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Parc Paul Mistral or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Grenoble. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in France. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat in Grenoble. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Bar Au RENCARD, a top recommendation for dinner tonight. Or, for a change of pace, Ciao a Te boasts a menu that's sure to impress. Also, be sure to check out La Bobine. Known as a local hotspot, it’s a great choice for tonight in Grenoble.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Le Groove stands out as an excellent choice for a post-dinner cocktail. Alternatively, Brasserie La Natation offers an ideal atmosphere to enjoy the pleasures of the night. Pub Shakesbeer is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 6-day road trip in France!

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Day 2

Day 2 – Grenoble, and Lyon

  • Lyon
  • Grenoble
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Drive 219 km, 4 hours 24 min

  • Museum of Grenoble
  • Bastille
  • Museum of the French Revolution - Domaine de Vizille
  • The Chartreuse Mountains
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Dive into day 2 of your remarkable road trip in France. Today you will explore Grenoble, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Lyon. You’ll stay here for 2 nights.

Kick off the day at Musée De Grenoble, a top pick for today’s sightseeing. This museum is rated an average of 4.5 out of 5 stars in 3,100 reviews.

Today is also your chance to visit Fort De La Bastille. Fort De La Bastille is a park with an average rating of 4.6 out of 5 stars from 7,303 reviews.

Museum Of The French Revolution - Domaine De Vizille is another top attraction we highly recommend you visit today. This museum is rated an average of 4.6 out of 5 stars by 5,504 visitors.

At the end of the day, you will drive to Lyon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Café du Rhône, an iconic dining spot in Lyon. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bulle - Restaurant de Fourvière - Guy Lassausaie, a popular restaurant in Lyon. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Vieille Canaille, a hidden gem nestled in Lyon. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like L' Antiquaire, known for its lively atmosphere. Black Forest Society is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, The James Joyce Pub offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in France.

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Day 3

Day 3 – Lyon, Caluire-et-Cuire, and Vaulx-en-velin

  • Lyon
  • Caluire-et-Cuire
  • Vaulx-en-Velin
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Drive 40 km, 1 hour 51 min

  • La Basilique Notre Dame de Fourvière
  • Lyon Cathedral
  • Place Bellecour
  • parc de la Tête d'Or
  • More

On day 3 of your road trip, you’ll start and end your day in Lyon, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Lyon, Caluire-et-Cuire, and Vaulx-en-velin. You still have 1 night left in Lyon.

Your sightseeing of the day begins at Basilica Of Notre-dame De Fourvière, a remarkable minor basilica where it’s easy to get lost in exploration. This top attraction is rated an average of 4.7 out of 5 stars in 25,765 reviews.

Next, satisfy your wanderlust at Lyon Cathedral. This catholic cathedral has an average rating of 4.6 out of 5 stars from 11,228 travelers.

Place Bellecour is another must-visit attraction. This renowned square offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.4 out of 5 stars by 20,560 travelers, it's one of the more popular places to see in the area.

Fasten your seatbelt and make your way to your next stop. Caluire-et-Cuire, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Lyon to Caluire-et-Cuire may take around 16 min without traffic disruptions. Upon arrival in Caluire-et-Cuire, we highly recommend checking out some of the top attractions.

A top pick for your self-guided sightseeing tour today is Parc De La Tête D'or. Previous visitors have rated this park an average of 4.6 out of 5 stars in 50,621 reviews.

Continue your road trip and head to your next destination, Vaulx-en-velin. This car ride takes around 13 min.

When you're ready to see some sights, Grand Parc Miribel Jonage is a great place to start. This park is rated an average of 4.3 out of 5 stars by 12,314 visitors.

When you’re done exploring for the day, you’ll return to Lyon and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Lyon's best restaurants.

Enjoy a delicious meal at Cactus Bar, a highly-rated dining destination in Lyon. If you're eager to try something different, consider L Bar food & drink, another top spot with a tantalizing menu. You might also want to secure a reservation at Flair Restaurant. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Lyon this evening.

Let the evening flow smoothly from dinner to drinks at Broc'bar, a top-rated bar in the area. For other recommendations, The Phantom Of The Opera provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Le Florian, Cocktails & Spirits offers a memorable night with diverse drink options and excellent service.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in France.

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Day 4

Day 4 – Lyon, Avignon, La Bégude de Vers-Pont-du-Gard, and Nimes

  • Nîmes
  • Avignon
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Drive 295 km, 3 hours 59 min

  • Jardin des doms
  • Palais des Papes
  • Pont d'Avignon
  • Pont du Gard
  • Jardin de La Fontaine
  • More

On day 4 of your road trip in France, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Avignon, La Bégude de Vers-Pont-du-Gard, and Nimes. In the evening, you’ll end up in Nimes, where you will stay for 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Avignon. This drive usually takes around 2 hours 20 min, without any stops or traffic disruptions.

Make Jardin Des Doms your first stop of the day. Previous visitors have rated this urban park an average of 4.5 out of 5 stars in 3,201 reviews.

Next up, make a stop at Palais Des Papes. With an average rating of 4.5 out of 5 stars by 36,931 visitors, it's easy to understand why so many people visit this palace every year. In fact, this attraction welcomes 616,210 annual visitors.

Pont Saint-benezet (le Pont D'avignon) is another attraction you can visit on this day of your vacation. This sightseeing destination has an average rating of 4.2 out of 5 stars by 17,658 visitors.

Continue your road trip and head to your next destination, La Bégude de Vers-Pont-du-Gard. This car ride takes around 32 min.

Seize the day by visiting some of the best attractions in the area, like Pont Du Gard. This extraordinary arch bridge has an average rating of 4.6 out of 5 stars from 29,439 visitors.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Nimes. Nimes offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you explore more of Nimes, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at La Galerie, a highly-rated dining destination in Nimes. If you're eager to try something different, consider Annaba Café, another top spot with a tantalizing menu. You might also want to secure a reservation at Hôtel des Tuileries. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Nimes this evening.

If you’re not ready to end the night just yet, La Bonne Mousse offers a perfect venue to relax and savor a drink. Similarly, O’flaherty’s is well-suited for those looking to unwind in a social setting. News Café is another excellent spot to enjoy a nightcap after a delightful meal.

Get a good night's sleep and look forward to another great day on the road in France!

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Day 5

Day 5 – Nimes, Arles, Les Baux-de-Provence, and Grenoble

  • Grenoble
  • Arles
  • Les Baux-de-Provence
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Drive 304 km, 4 hours 5 min

  • Arles Amphitheatre
  • More

Experience an unparalleled adventure on day 5 of your road trip in France. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Arles, and Les Baux-de-Provence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Grenoble. You will spend 1 night here for some well-deserved relaxation.

Continue your road trip and head to your next destination, Arles. This car ride takes around 35 min.

When you're ready to see some sights, Jardin D'été is a great place to start. This park is rated an average of 4.3 out of 5 stars by 1,025 visitors.

Another popular attraction you can visit today is Roman Theatre Of Arles. This sightseeing destination has an average rating of 4.4 out of 5 stars from 1,900 travelers.

We also recommend a stop at Arles Amphitheatre. The roman amphitheatre has been rated an average of 4.4 out of 5 stars by 13,060 visitors.

After soaking in Arles’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Les Baux-de-Provence. Expect your car journey to take a minimum of 27 min. When you arrive in Les Baux-de-Provence, it's time to take a break from the road.

Journey into the unknown at Château Des Baux-de-provence, a unique attraction awaiting your visit. This remarkable sightseeing destination has an average rating of 4.5 out of 5 stars from 13,346 reviews.

When you’re ready to continue your sightseeing, Carrières Des Lumières is a recommended place to visit. This point of interest is rated an average of 4.7 out of 5 stars in 22,791 reviews.

When you’re done exploring for the day, you’ll drive to Grenoble, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As dinnertime approaches, it's time to head out for a bite to eat in Grenoble. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Restaurant Une Semaine sur Deux, an iconic dining spot in Grenoble. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of restaurant brasserie L'Albatros Grenoble, a popular restaurant in Grenoble. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Ferme à Dédé, a hidden gem nestled in Grenoble. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Pub Des Copains, which offers the perfect atmosphere for a night out. Moreover, Blind Pig is another popular option for a drink or two.

Relax and reminisce about your day in France and look forward to more memorable moments to come!

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Day 6

Day 6 – Grenoble - departure day

  • Grenoble - Departure day
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  • Fontaine du Lion
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Day 6 of your road trip in France is your departure day. This is your chance to catch a last glimpse of Grenoble before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

On your last day in France, take time to indulge in shopping at Grenoble’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.

When you’re ready for some sightseeing, make your way to Fontaine Du Lion. This much-appreciated point of interest is rated 4.4 out of 5 stars in 773 reviews.

Before you conclude your road trip in France, drop by another restaurant for a last chance at a memorable dining experience in Grenoble.

If you're in the mood to try something new, consider Restaurant La Baratte, another top spot with a mouthwatering menu.

You’ll then say farewell to Grenoble. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in France!

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