12-Day Greece Road Trip from Thessaloniki traveling west to Trikala, Ioannina, and Larissa

Your road trip adventure in Greece begins as soon as you reach the incredible city of Thessaloniki. You’ll stay in Thessaloniki for 4 nights, experiencing all the best things to do and see in the city.

Thessaloniki has many popular destinations you can explore. You could visit attractions like the incredible Aristotelous Square. This attraction is a square and has an average rating of 4.7 out of 5 stars by 42,179 visitors.

When you're done sightseeing for the day, you'll check in at one of the best hotels or places to stay in the city. Your stay promises to be a delightful continuation of your exploration, providing comfort and tranquility to recharge for the adventures that lie ahead.

Thessaloniki also has several great bars that will fit all travel budgets. One of the best bars in the city of Thessaloniki is Pulp. This bar has an average rating of 4.7 out of 5 stars by 1,573 customers.

Another of the best bars in the city of Thessaloniki is Kitchen Bar. This bar is rated an average of 4.3 out of 5 stars by 9,067 customers.

Enjoy toasting the start of your 12-day vacation in Greece!

Day 2 of your road trip will take you to the best attractions Thessaloniki has to offer. Cherish the 3 nights you have left in Thessaloniki by discovering the best things there are to see and do in the city.

There are plenty of attractions, markets, and restaurants for you to experience today in the city of Thessaloniki. Your accommodation will be conveniently located close to several of the best attractions you won't want to miss.

You'll be able to visit more of the best travel destinations in the city of Thessaloniki, like the extraordinary The Umbrellas Sculpture by Zogolopoulos. This attraction is a top-tier point of interest and has an average rating of 4.7 out of 5 stars by 13,531 visitors.

Another of the best travel destinations in Thessaloniki is the spectacular Archaeological Museum of Thessaloniki. This attraction is an archaeological museum and is rated an average of 4.7 out of 5 stars by 6,924 visitors.

You could then travel to the amazing White Tower of Thessaloniki. This fortified tower has an average rating of 4.7 out of 5 stars by 50,663 visitors. Up to 290,192 people visit this popular attraction every year.

Agias Sofias Square is another stop you might want to add to your itinerary. This square is a popular destination among visitors in Thessaloniki. Rated at an average of 4.6 out of 5 stars by 10,128 visitors, it’s one many travelers find worthy a visit.

If you’re interested in seeing something outstanding today, then consider Kapani. Kapani is a market and popular attraction in Thessaloniki. More than 11,510 visitors have rated this place an average of 4.4 out of 5 stars.

Your discovery of Thessaloniki does not have to stop there. Check out the fantastic selection of tours and tickets offered in Thessaloniki on this day of your trip.

After a long day of exploring some of the most popular attractions in Greece, be sure to eat at Sebriko, which is considered one of the best restaurants in the city of Thessaloniki. This restaurant is a local favorite and has an average rating of 4.6 out of 5 stars by 2,978 customers.

Stopping at one of these popular bars is the perfect way to celebrate another incredible day in the magical city of Thessaloniki!

Day 3 of your road trip across Greece is another day in the magnificent Thessaloniki. You now have 2 nights left in Thessaloniki. Take the opportunity to experience more of the best attractions and activities in the city.

Thessaloniki offers plenty for you to see and do, and your hotel will be conveniently located near several of the area's best attractions.

One of the best travel destinations you can travel to in the city of Thessaloniki is the stunning Holy Church of Saint Demetrius, Patron Saint of Thessalonica. This has an average rating of 4.9 out of 5 stars by 5,576 visitors.

You could also spend some time visiting the spectacular Arch of Galerius and Rotunda in the city of Thessaloniki. This attraction is a tetrapylon and is rated an average of 4.6 out of 5 stars by 11,979 visitors.

Another attraction you could visit in the city of Thessaloniki is the incredible Atatürk Museum. This attraction is a house museum and has an average rating of 4.6 out of 5 stars by 7,420 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit the fantastic Heptapyrgion of Thessaloniki. This must-see tourist destination and travel destination is rated an average of 4.6 out of 5 stars by 5,550 visitors.

If you’re keen to explore even more, then consider a visit to the outstanding Acropolis of Thessaloniki. This park is a much-appreciated attraction with an average rating of 4.7 out of 5 stars from 3,133 visitors.

Today you’ll also have the opportunity to take part in a popular tour. You’ll be excited to learn that there are plenty of options for top-rated tours and activities in Thessaloniki you could sign up for on this day of your vacation. Choose among the best tours before or after booking.

When it’s time to eat, the city of Thessaloniki has restaurants and bars to fit all budgets.

We recommend you try one of the best restaurants in the city of Thessaloniki, Charoupi. The restaurant has an average rating of 4.6 out of 5 stars by 2,912 customers.

Alternatively, if you’re hungry to try a top restaurant in the city of Thessaloniki that locals enjoy, eat at The Rouga. This restaurant is rated an average of 4.6 out of 5 stars by 2,900 customers.

Another of the best restaurant options in the city of Thessaloniki is The Greek. This restaurant has an average rating of 4.5 out of 5 stars by 3,117 customers.

Toast to another amazing day in the city of Thessaloniki!

Today, you'll hit the road once again, setting off on a journey towards the stunning city of Trikala. You’ll stay in Trikala for 2 nights. But before you begin your drive, we recommend taking the time to explore some of Trikala’s must-see attractions and local hotspots.

If you’re curious to see more of Trikala, start your day with a visit to the amazing Sports Park St. George Trikala. This much-appreciated park and attraction is rated 4.8 out of 5 stars by 1,394 visitors.

You could also stop at another of the best local travel destinations in the area, the fascinating Matsopoulos Mill. This museum and spectacular attraction has an average rating of 4.7 out of 5 stars from 926 visitors.

We also recommend you spend some time at the popular Matsopoulos Park to make the most of your road trip across Greece. The spectacular Matsopoulos Park is a park that has been rated an average of 4.7 out of 5 stars by 8,871 visitors.

The lovely Central Bridge is yet another attraction you could pay a visit. Around 2,951 visitors have left this must-see tourist destination average ratings of 4.8 out of 5 stars.

If you feel like visiting another type of sight or don’t want to jump into the car quite yet, spend some time at the spectacular Trikala City Center Square. This attraction is a park rated an average of 4.7 out of 5 stars in 3,935 reviews.

After soaking up all the sights and sounds that Trikala has to offer, you'll be ready to hit the open road and continue your unforgettable road trip towards the city of Trikala. Trikala offers plenty of options for top-rated hotels and other places to stay that fit all travel budgets.

After you’ve settled into your accommodation, we recommend a dinner at the popular To Chani. This popular restaurant is one of the locals’ most recommended restaurants in the city, with ratings of 4.6 out of 5 stars in 2,894 reviews.

The remarkable Palia Istoria is another top restaurant in Trikala we recommend. This restaurant offers an unforgettable dining experience and is rated an average of 4.5 out of 5 stars by 1,654 customers.

If you would rather go somewhere else, the famous Ladophánaro is also an excellent choice. This well-loved restaurant is rated an average of 4.6 out of 5 stars by 1,212 customers.

After your meal, we recommend you drink at one of the best bars in Trikala, the fantastic Krypti Mpar. This bar has an average rating of 4.7 out of 5 stars by 620 customers.

To end your night the best way possible, we recommend going to the wonderful Ivy. This bar offers a great variety of drinks and has been rated an average of 4.6 out of 5 stars by 766 customers.

Another bar with a great atmosphere is The Love Shake. This bar is rated an average of 4.6 out of 5 stars by 655 customers, so don’t forget to check this one out as well!

Celebrate another amazing vacation day filled with adventure in Greece!

You still have 1 night left in Trikala.

One of the best travel destinations you can make time for at the start of this day is Holy Church of Porta Panagia (13th c. ). This incredible attraction is a church and has an average rating of 4.9 out of 5 stars from 632 visitors.

Hanging Gate Bridge of Pyli is another popular attraction you'll visit. This spectacular attraction is rated 4.7 out of 5 stars by 1,091 visitors.

Another of the best travel destinations you can visit is Stone bridge and waterfall of Palaiokarya. This amazing attraction is a top-tier point of interest and is rated an average of 4.9 out of 5 stars by 3,860 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit the outstanding Elati Trikalon. This best-rated sightseeing destination and place of interest is rated an average of 4.7 out of 5 stars by 655 visitors.

To do something one-of-a-kind today, you can join a popular tour. Check out all the fun and eye-opening experiences you can try out in Greece to make your travel experience in the country more memorable.

When you’re done exploring for the day, you’ll drive to your accommodation in the city of Trikala.

We recommend eating at one of the best restaurants in the city of Trikala, like The tavern Tsikali. This restaurant has an average rating of 4.3 out of 5 stars by 542 customers.

Gyrománia is another of the best restaurant options in the city of Trikala. This restaurant is rated an average of 4.4 out of 5 stars by 150 customers.

After dinner, visit one of the best bars in the city of Trikala, Vesper, Backyard Homage. This bar is rated an average of 4.6 out of 5 stars by 548 customers.

You can also enjoy drinks at a popular bar that locals recommend, like ALVEO. This bar has an average rating of 4.5 out of 5 stars by 454 customers.

BitterSweet Cocktail Bar is another of the best bars in the city of Trikala. This bar is rated an average of 4.5 out of 5 stars by 315 customers.

Raise your glass and relax after another big day of your road trip adventure through Greece!

Day 6 of your road trip through Greece gives you the opportunity to experience two places in one day. You will stay in Ioannina for 4 nights. Have a hearty breakfast and get excited for a wonderful day ahead!

One of the best places to visit today in Trikala is the amazing Kentro Ereynas - Moyseio Tsitsani. This attraction is a museum that is rated an average of 4.7 out of 5 stars by 1,303 visitors.

You could also stop at the incredible congregational mosque, Osman Shah Mosque. With an average rating of 4.4 out of 5 stars by 868 visitors, this attraction is one of the top sights in the area.

Another unforgettable travel destination in the Trikala is the outstanding Byzantine Castle of Trikala. This popular best-rated sightseeing destination and travel destination has an average rating of 4.6 out of 5 stars by 2,091 visitors.

There are many top-rated experiences you can include in your travel plan to add flavor to your road trip in Greece. Browse all of your options and reserve your slot before it's too late.

At the end of the day, you will drive to the city of Ioannina, where you will access the best hotels and places to stay.

After dinner, visit Palia Agora, which is considered one of the best bars in the city of Ioannina. This bar is rated an average of 4.7 out of 5 stars by 1,278 customers.

You can also enjoy drinks at a popular bar like Scala. This bar has an average rating of 4.6 out of 5 stars by 909 customers.

Raise your glass in celebration of your incredible road trip adventure through Greece!

On day 7 of your road trip across Greece, you’ll have the perfect day exploring the wonderful city of Ioannina. You’ll stay in Ioannina for 3 nights, meaning you have plenty of time to discover the best things to see and do in the area.

We recommend you stay at the Saz City Life Hotel, one of the best 4-star hotels in the city of Ioannina. This hotel has an average rating of 4.6 out of 5 stars by 810 guests.

The best luxury hotel option in the city of Ioannina is the 5-star Grand Serai Congress & Spa. The hotel is rated an average of 4.4 out of 5 stars by 1,602 guests.

One of the best hotels we recommend in the city of Ioannina is the 3-star Filokalia Hotel. This 3-star hotel has an average rating of 4.4 out of 5 stars by 372 guests.

Our flexible booking system will automatically provide you with the best alternatives if these hotels are not available.

You'll have easy access to popular travel destinations in the city of Ioannina, like the outstanding Moyseio Ellinikis Istorias Payloy Vrelli. This attraction has an average rating of 4.8 out of 5 stars by 7,022 visitors.

Museum "Arslan Pasha" is another popular attraction you could visit in the city of Ioannina. This incredible attraction is a best-rated sightseeing destination and has been rated an average of 4.4 out of 5 stars by 1,182 visitors.

One of the best attractions you could visit in the city of Ioannina is the extraordinary Ioannina Castle. This castle is rated an average of 4.7 out of 5 stars in 11,412 reviews.

As the day moves along, one attraction you’ll probably want to visit is the incredible Cave of Perama. Around 6,636 visitors have given this show cave an average rating of 4.8 out of 5 stars.

Today you'll also have the opportunity to spend some time at the fantastic Iera Moni Ntoyrachanis. Iera Moni Ntoyrachanis is a popular place of worship, rated an average of 4.9 out of 5 stars by 451 travelers.

Come to Ioannina prepared by adding some tours and tickets to your vacation package. Book a popular and budget-friendly activity you can do on this day in Ioannina.

After a day of exploring, try one of the best restaurants in the city of Ioannina.

We recommend you eat at a delicious restaurant that locals enjoy, like Metsovitiki Folia, after your day of exploring the city of Ioannina. This excellent restaurant has an average rating of 4.6 out of 5 stars by 2,924 customers.

Locals recommend Omilos, one of the best bars in the city of Ioannina, for a refreshing evening drink to finish your day. This bar is rated an average of 4.5 out of 5 stars by 900 customers.

Alternatively, you could choose another of the most popular bars in the city of Ioannina, Chevalier. This bar has an average rating of 4.7 out of 5 stars by 739 customers.

It's a perfect place to relax and enjoy another amazing evening in Greece.

Day 8 of your road trip will take you to the best attractions Ioannina has to offer. Cherish the 2 nights you have left in Ioannina by discovering the best things there are to see and do in the city.

There are plenty of attractions, markets, and restaurants for you to experience today in the city of Ioannina. Your accommodation will be conveniently located close to several of the best attractions you won't want to miss.

You'll be able to visit more of the best travel destinations in the city of Ioannina, like the extraordinary Silversmithing museum of Ioannina. This attraction is a museum and has an average rating of 4.8 out of 5 stars by 1,485 visitors.

Another of the best travel destinations in Ioannina is the spectacular Byzantine Museum of Ioannina. This attraction is a museum and is rated an average of 4.4 out of 5 stars by 493 visitors.

You could then travel to the amazing Ali Pasha's Tomb. This top-tier point of interest has an average rating of 4.6 out of 5 stars by 221 visitors.

Fethiye Mosque is another stop you might want to add to your itinerary. This mosque is a popular destination among visitors in Ioannina. Rated at an average of 4.6 out of 5 stars by 333 visitors, it’s one many travelers find worthy a visit.

If you’re interested in seeing something outstanding today, then consider Ich Kale Acropolis of Ioannina. Ich Kale Acropolis of Ioannina is a must-see tourist destination and popular attraction in Ioannina. More than 3,163 visitors have rated this place an average of 4.8 out of 5 stars.

Your discovery of Ioannina does not have to stop there. Check out the fantastic selection of tours and tickets offered in Ioannina on this day of your trip.

After a long day of exploring some of the most popular attractions in Greece, be sure to eat at SEIRIOS, which is considered one of the best restaurants in the city of Ioannina. This restaurant is a local favorite and has an average rating of 4.4 out of 5 stars by 2,410 customers.

When you’ve finished your meal, To Dodeka Cafe Bar is one of the best bars in the city of Ioannina for an after-dinner drink. This bar has an average rating of 4.3 out of 5 stars by 809 customers.

OPEN BAR is another of the most popular bars in the city of Ioannina. This bar is rated an average of 4.3 out of 5 stars by 770 customers.

Alternatively, a great bar that locals enjoy in the city of Ioannina is Route 66 Bar. Route 66 Bar has an average rating of 4.7 out of 5 stars by 449 customers.

Stopping at one of these popular bars is the perfect way to celebrate another incredible day in the magical city of Ioannina!

Day 9 of your road trip across Greece is another day in the magnificent Ioannina. You now have 1 night left in Ioannina. Take the opportunity to experience more of the best attractions and activities in the city.

Ioannina offers plenty for you to see and do, and your hotel will be conveniently located near several of the area's best attractions.

One of the best travel destinations you can travel to in the city of Ioannina is the stunning Kiápha. This has an average rating of 4.4 out of 5 stars by 130 visitors.

You could also spend some time visiting the spectacular Kaloutsiani Mosque in the city of Ioannina. This attraction is a best-rated sightseeing destination and is rated an average of 4 out of 5 stars by 667 visitors.

Another attraction you could visit in the city of Ioannina is the incredible The Clock Tower of Ioannina. This attraction is a top-tier point of interest and has an average rating of 4.7 out of 5 stars by 1,943 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit the fantastic Litharitsia park. This best-rated sightseeing destination and travel destination is rated an average of 4.5 out of 5 stars by 2,135 visitors.

If you’re keen to explore even more, then consider a visit to the outstanding Archaeological Museum of Ioannina. This archaeological museum is a much-appreciated attraction with an average rating of 4.6 out of 5 stars from 553 visitors.

Today you’ll also have the opportunity to take part in a popular tour. You’ll be excited to learn that there are plenty of options for top-rated tours and activities in Ioannina you could sign up for on this day of your vacation. Choose among the best tours before or after booking.

When it’s time to eat, the city of Ioannina has restaurants and bars to fit all budgets.

We recommend you try one of the best restaurants in the city of Ioannina, Fysa Roufa. The restaurant has an average rating of 4.5 out of 5 stars by 1,585 customers.

After your meal, we recommend you get a drink at one of the best bars in the city of Ioannina, Hogwarts Tales And Spirits. This bar has an average rating of 4.4 out of 5 stars by 557 customers.

For one of the best bar experiences that locals enjoy in the city of Ioannina, we recommend the cocktails at Spitaki. This bar has been rated an average of 4.5 out of 5 stars by 500 customers.

Another of the best bars in the city of Ioannina is Trypokárydos. This bar has an average rating of 4.7 out of 5 stars by 418 customers.

Toast to another amazing day in the city of Ioannina!

As you rise to greet the dawn on day 10 of your epic road trip in Greece, you'll awaken to the bustling city of Kalambaka. Today, you'll hit the road once again, setting off on a journey towards the stunning city of Larissa. You’ll stay in Larissa for 1 night. But before you begin your drive, we recommend taking the time to explore some of Kalambaka’s must-see attractions and local hotspots.

If you’re curious to see more of Kalambaka, start your day with a visit to the amazing Meteora. This much-appreciated monastery and attraction is rated 4.9 out of 5 stars by 35,413 visitors.

You could also stop at another of the best local travel destinations in the area, the fascinating The Great Meteoron Holy Monastery of the Transfiguration of the Saviour. This place of worship and spectacular attraction has an average rating of 4.8 out of 5 stars from 8,462 visitors.

We also recommend you spend some time at the popular Monastery of Varlaam to make the most of your road trip across Greece. The spectacular Monastery of Varlaam is a church that has been rated an average of 4.8 out of 5 stars by 6,833 visitors.

After soaking up all the sights and sounds that Kalambaka has to offer, you'll be ready to hit the open road and continue your unforgettable road trip towards the city of Larissa. Larissa offers plenty of options for top-rated hotels and other places to stay that fit all travel budgets.

After you’ve settled into your accommodation, we recommend a dinner at the popular Las Ramblas Coffeebar. This popular restaurant is one of the locals’ most recommended restaurants in the city, with ratings of 4.5 out of 5 stars in 2,338 reviews.

The remarkable Vosporos | Restaurant * Bar is another top restaurant in Larissa we recommend. This restaurant offers an unforgettable dining experience and is rated an average of 4.5 out of 5 stars by 990 customers.

If you would rather go somewhere else, the famous Greek restaurant "O Tasos" is also an excellent choice. This well-loved restaurant is rated an average of 4.8 out of 5 stars by 713 customers.

After your meal, we recommend you drink at one of the best bars in Larissa, the fantastic Gossip Downtown. This bar has an average rating of 4.6 out of 5 stars by 1,557 customers.

To end your night the best way possible, we recommend going to the wonderful Klímax. This bar offers a great variety of drinks and has been rated an average of 4.3 out of 5 stars by 1,734 customers.

Another bar with a great atmosphere is KUBRICK Pure Social “ Club ”. This bar is rated an average of 4.5 out of 5 stars by 1,128 customers, so don’t forget to check this one out as well!

Celebrate another amazing vacation day filled with adventure in Greece!

Rise and shine on day 11 of your road trip in Greece. Today, you'll wake up in Larissa and embark on a scenic drive to Thessaloniki, where you'll stay at one of the best hotels for 1 night. Seize the opportunity to explore spectacular attractions in Larissa and Central Macedonia before you reach your end destination for the day.

It’s hard not to feel excited about visiting attractions in a destination as lovely as Larissa. When you’re eager to explore the city and nearby areas, we recommend visiting some local favorites, such as the wonderful Municipal Art Gallery of Larissa G. I. Katsigras Museum. This attraction is a museum that has an average rating of 4.6 out of 5 stars from 1,036 visitors.

You could also stop at the incredible Diachronic museum of Larissa. This attraction, a beloved archaeological museum, has an average rating of 4.8 out of 5 stars from 654 visitors.

If you have time, another site you could explore in Larissa is the stunning First Ancient Theatre, Larissa. This greek theatre and travel destination has an average rating of 4.6 out of 5 stars by 589 visitors.

One of the most popular attractions you can visit is the remarkable Museum of the Royal Tombs at Aigai (Aegae). This attraction is a museum that has an average rating of 4.8 out of 5 stars from 8,329 visitors.

If you want to explore more, visit the incredible Holy Shrine of the Virgin Mary Soumela. This place of worship and attraction has an average rating of 4.9 out of 5 stars from 6,055 reviews.

Another site you could visit today is the top-rated Lazaristes Monastery. This top-tier point of interest and travel destination is rated an average of 4.6 out of 5 stars by 3,480 visitors.

When you're done with your sightseeing in Central Macedonia, it's time to continue your drive to the city of Thessaloniki. When you arrive in Thessaloniki you’ll check in at one of the best hotels in the area.

We recommend you end the day with a dinner at a popular restaurant near your accommodation, like Palati Thessaloniki. This restaurant offers various delicious and comforting meals and has an average rating of 4.4 out of 5 stars from 2,775 customers.

After dinner, visit Apallou to enjoy a couple of drinks and relax. This bar is one of the best in Thessaloniki, with an average rating of 4.4 out of 5 stars by 2,504 customers.

This bar is a great spot to meet new friends and celebrate your vacation.

End your day by raising your glass in celebration of your incredible road trip adventure in Greece, and look forward to more great days to come!

Day 12 of your road trip in Greece is your departure day. This is your chance to catch one last glimpse of Thessaloniki before saying goodbye to this wonderful destination. When you have time to explore the area before you make your way home, we recommend visiting some of the following attractions.

Thessaloniki Waterfront is an extraordinary attraction you could visit to enjoy your last day in Thessaloniki. This best-rated sightseeing destination and popular site of interest has an average rating of 4.8 out of 5 stars by 1,957 visitors.

Take a stroll along the main shopping streets of Thessaloniki and find some souvenirs to remind you of your road trip in Greece.

You’ll then say farewell to Thessaloniki. We wish you a pleasant journey home, with many wonderful memories of your unforgettable vacation in Greece!