5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Trikala

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Experience the freedom of the open road in Greece as you embark on an unforgettable 5-day road trip! This experience caters to every traveler, featuring destinations like Thessaloniki, Trikala, and Kastraki.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki and 1 night in Trikala. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Meteora, learn more about the unique The Umbrellas Sculpture By Zogolopoulos, and immerse yourself in the vibrant atmosphere of Arch Of Galerius And Rotunda.

As you hit the open road and drive through Thessaloniki, Trikala, and Kastraki, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
Aristotelous SquareWhite Tower of ThessalonikiArchaeological Museum of ThessalonikiThe Umbrellas by ZongolopoulosTsimiski Street
KapaniChurch of St DemetriosAtatürk MuseumArch of Galerius
Trikala City Center SquareMatsopoulos ParkThe Great Meteoron Holy Monastery of the Transfiguration of the SaviourMeteora
Agias Sofias Square

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Say hello to Thessaloniki! Your exciting road trip through Greece is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Thessaloniki for 2 nights before you continue your adventure!

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Thessaloniki. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Dine in style at Kitchen Bar, a top recommendation for dinner tonight. Or, for a change of pace, The Greek boasts a menu that's sure to impress. Also, be sure to check out Phanós. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

After savoring a delicious meal, step into the vibrant nightlife at Beetle Bar, where the evening is just getting started. In the same way, Vogatsikou 3 offers a unique charm perfect for experiencing the local bar scene in Thessaloniki. Souel is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 5-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
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Drive 7 km, 57 min

  • Aristotelous Square
  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • The Umbrellas by Zongolopoulos
  • Tsimiski Street
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Day 2 of your road trip across Greece promises a magnificent time exploring Thessaloniki. You have 1 night left in Thessaloniki. Take the opportunity to experience more of the best attractions and activities in the city.

Tsimiski Street is one of the highlights of today. Take your time exploring this iconic street in Thessaloniki, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Thessaloniki is brimming with adventures. Today’s wonderful stops include a public square, a monument, a museum, an art installation and much more! Begin your sightseeing adventure at the captivating Aristotelous Square and allow yourself time to explore. Just a short distance away you'll find your next stop, White Tower Of Thessaloniki, an awe-inspiring monument that draws visitors from far and near.

Continue your journey to Archaeological Museum Of Thessaloniki, one of the city’s most up-and-coming spots that you shouldn’t miss. Another great site to visit is the locally renowned The Umbrellas Sculpture By Zogolopoulos.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Enjoy a delicious meal at Mamalouka, a highly-rated dining destination in Thessaloniki. If you're eager to try something different, consider Clochard, another top spot with a tantalizing menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Thessaloniki this evening.

Continue the enjoyment post-dinner at Castra- All Day Terrace Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Barbaben - Bar/ba/ben offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Apallou. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Trikala
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Drive 216 km, 3 hours 10 min

  • Kapani
  • Church of St Demetrios
  • Atatürk Museum
  • Arch of Galerius
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Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Thessaloniki. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Trikala. You will spend 1 night here for some well-deserved relaxation.

Get ready for a day filled with fun adventures, picturesque spots, and history-rich sites in the charming city of Thessaloniki. Your adventure starts at Kapani, a well-known local hot spot. Another notable attraction to explore is Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica. This curiosity-inducing church is known for its photogenic appeal.

After soaking in the highlights of these sights, take some time to wander Thessaloniki's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Atatürk Museum. This instagrammable museum offers a fascinating experience that many visitors find memorable. Arch Of Galerius And Rotunda is also worth visiting.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Trikala. Trikala offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Trikala, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at ALVEO, a top-rated dining destination in Trikala. If you're in the mood to try something new, consider Trikala Fortress, another top spot with a mouthwatering menu. You might also want to secure a reservation at Palia Istoria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Trikala this evening.

Continue your evening by exploring the vibrant nightlife scene at Soyita Art Cafe, a prime destination for a thrilling night out. Also, don’t forget to check out Factory Café, a bar that offers unique local touches. Likewise, The Love Shake provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 4

Day 4

  • Trikala
  • Thessaloniki
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Drive 257 km, 4 hours 16 min

  • Trikala City Center Square
  • Matsopoulos Park
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Meteora
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Dive into day 4 of your remarkable road trip in Greece. Today you will explore Trikala and Kastraki, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki. You’ll stay here for 1 night.

Today’s itinerary in Trikala covers several incredible sights, including a public square, a park, and a monastery. Start your adventure at Trikala City Center Square. This often recommended public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the awe-inspiring wonders of Matsopoulos Park, a must-see park in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This worthwhile monastery offers an enriching experience. For a change of pace, head to Meteora, where you can take in picturesque features. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Enoches Bar, a top recommendation for dinner tonight. Or, for a change of pace, O Loytros boasts a menu that's sure to impress. Also, be sure to check out rOOTS. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

To truly maximize your evening out, consider visiting Peiratis Cafe-bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to In Rock Cafe Bar, another bar with an inviting ambiance. Similarly, Tribeca also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 5

Day 5

  • Thessaloniki - Departure day
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  • Agias Sofias Square
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Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Agias Sofias Square. This well-known public square is a popular place to see in the city.

Maximize your last day in Greece and go on a shopping spree in Thessaloniki’s shopping center, the lively Modiano Market. Browse for souvenirs to remind you of your wonderful journey in Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

If you're eager to try something different, consider Agora Ouzeri, another top spot with a tantalizing menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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