6-Day Greece Road Trip from Thessaloniki traveling south to Trikala

Perfect travel plans
Everything included
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Description

Summary

Duration
6 days & 5 nights
Available
Jan. - Dec.
Hotel
5 nights included
Car rental
6 days included
Flights
Optional
Travel app
All vouchers, itinerary, & map

Description

Escape the ordinary with this exciting 6-day road trip through Greece that promises to leave you speechless. With this exciting adventure, you will have the chance to explore the diverse landscapes and local cultures of Thessaloniki, Edessa, Naoussa, Vergina, Trikala, and Kastraki. Pack your bags, hit the road, and prepare for an unforgettable journey where every moment becomes a lasting story.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 4 nights in Thessaloniki and 1 night in Trikala. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Thessaloniki, Edessa, Naoussa, Vergina, Trikala, and Kastraki, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Included

Hotel, 5 nights
Rental car, 6 days
CDW Insurance
Step-by-step guide
Personal travel agent
24/7 travel support

Destinations

Naoysa
Vergina
Thessaloniki Municipal Unit - city in GreeceThessaloniki / 4 nights
Photo of Medieval tower with a clock ,Trikala Fortress, Central Greece.Trikala / 1 night
Kastraki
Photo of panoramic aerial view of Edessa Waterfall, Central Macedonia, Greece.Edessa

Map

Attractions

Photo of aerial drone view of iconic historic landmark ,old byzantine White Tower of Thessaloniki or Salonica, North Greece.White Tower of Thessaloniki
Photo of aerial drone panoramic view of iconic landmark Aristotelous square in the heart of Thessaloniki or Salonica, North Greece.Aristotelous Square
Photo of Sunset over monastery of Rousanou and Monastery of St. Nicholas Anapavsa in famous greek tourist destination Meteora in Greece.Meteora
Photo of Waterfall in the park of the city of Edessa, Greece.Waterfalls Park, Edessa
The Umbrellas by Zongolopoulos, 1st District of Thessaloniki, Thessaloniki Municipal Unit, Municipality of Thessaloniki, Thessaloniki Regional Unit, Central Macedonia, Macedonia and Thrace, GreeceThe Umbrellas by Zongolopoulos
photo of view of Arch of Galerius and Rotunda, Thessaloniki, Greece.Arch of Galerius and Rotunda
photo of view of Agia Sofia Square travel guide, Thessaloniki, Greece.Agias Sofias Square
photo of View of a fruits and vegetables stand at the outdoor market Kapani in Thessaloniki Greece,Thessaloniki Greece.Kapani
Ιερά Μονή Μεγάλου Μετεώρου - Μεταμορφώσεως του Σωτήρος, Kalampaka Municipality, Trikala Regional Unit, Thessaly, Thessaly and Central Greece, GreeceThe Great Meteoron Holy Monastery of the Transfiguration of the Saviour
Matsopoulos Park, Trikala Municipality, Trikala Regional Unit, Thessaly, Thessaly and Central Greece, GreeceMatsopoulos Park
Museum of the Royal Tombs at Aigai (Aegae), Veria, Imathia Regional Unit, Central Macedonia, Macedonia and Thrace, GreeceMuseum of the Royal Tombs at Aigai (Aegae)
Monastery of Varlaam, Kalampaka Municipality, Trikala Regional Unit, Thessaly, Thessaly and Central Greece, GreeceMonastery of Varlaam
photo of view ofAtatürk useumM, Thessaloniki, Greece.Atatürk useumM
Trikala City Center Square, Trikala Municipality, Trikala Regional Unit, Thessaly, Thessaly and Central Greece, GreeceTrikala City Center Square
Central Bridge, Trikala Municipality, Trikala Regional Unit, Thessaly, Thessaly and Central Greece, GreeceCentral Bridge
Trikala Byzantine Castle, Trikala Municipality, Trikala Regional Unit, Thessaly, Thessaly and Central Greece, GreeceByzantine Castle of Trikala
Municipal Park of Naoussa
Polycentric Museum of Aigai (Aegae) - Main Building
Κέντρο Έρευνας - Μουσείο Τσιτσάνη, Trikala Municipality, Trikala Regional Unit, Thessaly, Thessaly and Central Greece, GreeceΚέντρο Έρευνας - Μουσείο Τσιτσάνη

Flights
Yes
No

Round trip
Economy
Round trip
Economy

Travel details

Flights

Round trip
Economy
Round trip
Economy
Travel dates

Include flights?

Yes
No

Travelers

Rooms

Flights

Car
Yes
No

Car

Small car

Small car

Category
small car
Transmission
People
Large bags
Medium car

Medium car

Category
Medium
Transmission
People
Large bags
Premium car

Premium car

Category
premium car
Transmission
People
Large bags

Hotels

Personalize your itinerary

Day 1

Day 1 – Thessaloniki - arrival day

  • Thessaloniki - Arrival day
  • More
  • Aristotelous Square
  • More

Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 3 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Aristotelous Square or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Thessaloniki. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

As a top-rated it is an ideal choice in the city. Enjoy a lovely meal at Kitchen Bar, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, The Greek is another top choice with a popular menu. You could also check for a table at Ενοχές Bar. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Thessaloniki tonight.

After enjoying a fulfilling meal, continue your evening at Vogatsikou 3, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Castra- All Day Terrace Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Apallou provides an excellent environment for a relaxed and enjoyable evening.

Raise a toast to the start of your 6-day road trip in Greece!

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Day 2

Day 2 – Thessaloniki

  • Thessaloniki
  • More

Drive 6 km, 56 min

  • Kapani
  • Agias Sofias Square
  • White Tower of Thessaloniki
  • Arch of Galerius and Rotunda
  • Atatürk useumM
  • More

Day 2 offers a multitude of experiences. You will stay in Thessaloniki for 2 nights more, offering you enough time to explore at a relaxed pace.

Kick off the day at Kapani, a top pick for today’s sightseeing. This market is rated an average of 4.4 out of 5 stars in 11,618 reviews.

Today is also your chance to visit Agias Sofias Square. Agias Sofias Square is a square with an average rating of 4.6 out of 5 stars from 10,231 reviews.

White Tower of Thessaloniki is another top attraction we highly recommend you visit today. This fortified tower is rated an average of 4.7 out of 5 stars by 51,335 visitors. In a single year, this fortified tower hosts approximately 290,192 visitors.

Beyond the attractions mentioned above, you also have the opportunity to visit Arch of Galerius and Rotunda. This tetrapylon is rated an average of 4.6 out of 5 stars by 12,215 visitors.

Lastly, don’t miss out on Atatürk Museum, a famous house museum in Thessaloniki. This attraction is rated an average of 4.6 out of 5 stars by 7,650 travelers.

There are plenty of experiences you can choose from in Greece that will add excitement to your vacation. When you’re keen to discover what else Thessaloniki has in store for you, use this day to go on a tour. This tour allows curious travelers like you to experience the best of the country. You can make the most of your time in Greece by scrolling down and selecting tours and activities to include on your itinerary for the day.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at rOOTS, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider Menta, another top spot with a mouthwatering menu. You might also want to secure a reservation at Opsopoion Maganeiai. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

Explore the vibrant nightlife at Tribeca after your meal, a hub for lively evenings and memorable moments. Or, head to Kafodeio Greek for a great selection of flavorful drinks and a charming setting. Furthermore, Pulp is perfect for those looking to extend their night with a touch of local flavor.

Relax and reminisce about your day in Greece and look forward to more memorable moments to come!

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Day 3

Day 3 – Thessaloniki, Edessa, Naoussa, and Vergina

  • Thessaloniki
  • Edessa
  • Naoysa
  • Vergina
  • More

Drive 218 km, 3 hours 25 min

  • Waterfalls Park, Edessa
  • Municipal Park of Naoussa
  • Polycentric Museum of Aigai (Aegae) - Main Building
  • Museum of the Royal Tombs at Aigai (Aegae)
  • More

Wake up to day 3 of your extraordinary road trip in Greece. With 1 night left in Thessaloniki, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’re ready to jump back into the car and say goodbye to Thessaloniki, you’ll hit the road in the direction of Edessa. This drive usually takes around 1 hour 18 min. When you arrive, enjoy some sightseeing.

A top pick for your self-guided sightseeing tour today is Waterfalls Park, Edessa. Previous visitors have rated this urban park an average of 4.8 out of 5 stars in 19,283 reviews.

When you’ve had your share of Edessa, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Naoussa. Your travel time is around 36 min.

Make Municipal Park of Naoussa your first stop of the day. Previous visitors have rated this park an average of 4.7 out of 5 stars in 2,179 reviews.

Embrace the thrill of the open road as you wave goodbye to Naoussa and set your GPS to Vergina. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 35 min. Upon reaching Vergina, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Drop by the renowned Polycentric Museum of Aigai (Aegae) - Main Building. This popular museum has been rated an average of 4.7 out of 5 stars by 1,872 visitors.

Another unforgettable place to experience is Museum of the Royal Tombs at Aigai (Aegae). Rated 4.8 out of 5 stars by 8,578 visitors, this museum deserves a spot on today's sightseeing itinerary.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Thessaloniki.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Don’t miss out on dining at The Blue Cup | Creative bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider Pantheon Bar, another top spot with a mouthwatering menu. You might also want to secure a reservation at LOCAL Thessaloniki. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

Savor another day of unforgettable experiences in Greece!

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Day 4

Day 4 – Thessaloniki and Trikala

  • Trikala
  • More

Drive 219 km, 3 hours 9 min

  • Matsopoulos Park
  • Byzantine Castle of Trikala
  • Central Bridge
  • Κέντρο Έρευνας - Μουσείο Τσιτσάνη
  • Trikala City Center Square
  • More

On day 4 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Trikala. In the evening, you’ll end up in Trikala, where you will stay for 1 night.

Fasten your seatbelt and make your way to your next stop. Trikala, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Thessaloniki to Trikala may take around 2 hours 32 min without traffic disruptions. Upon arrival in Trikala, we highly recommend checking out some of the top attractions.

Begin your sightseeing with a visit to Matsopoulos Park. This extraordinary park is rated an average of 4.7 out of 5 stars by 8,887 visitors.

Next, make your way to Byzantine Castle of Trikala. This top attraction is a point of interest with an average rating of 4.6 out of 5 stars by 2,098 visitors.

We also recommend a visit to Central Bridge. This sightseeing destination is rated 4.8 out of 5 stars by 2,978 travelers.

If you’re keen to keep exploring, visit Κέντρο Έρευνας - Μουσείο Τσιτσάνη. This highly recommended sightseeing destination has received an average rating of 4.8 out of 5 stars from 1,372 travelers.

Today is also your chance to spend some time at Trikala City Center Square. This park is rated an average of 4.7 out of 5 stars by 3,972 travelers.

When you’re done exploring for the day, you’ll drive to Trikala, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Trikala's best restaurants.

Make sure to book a table at ALVEO, a popular restaurant in Trikala. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of countless food lovers. Alternatively, experience a taste of Trikala at Trikala Fortress, a popular local restaurant. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. Another top-rated restaurant to try is Palia Istoria. As a dining spot that gains consistently high praise from guests, it’s an ideal choice to enhance your time to Trikala tonight.

If you’re not ready to end the night just yet, Σουίτα Art Cafe offers a perfect venue to relax and savor a drink. Similarly, Factory Café is well-suited for those looking to unwind in a social setting. The Love Shake is another excellent spot to enjoy a nightcap after a delightful meal.

Say good night to Trikala and look forward to another great day of your road trip in Greece!

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Day 5

Day 5 – Trikala, Kastraki, and Thessaloniki

  • Thessaloniki
  • Kastraki
  • More

Drive 255 km, 4 hours 6 min

  • Monastery of Varlaam
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Meteora
  • More

Dive into day 5 of your remarkable road trip in Greece. Today you will explore Kastraki, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki. You’ll stay here for 1 night.

When you’ve had your share of Kastraki, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Thessaloniki. Your travel time is around 2 hours 43 min.

Your sightseeing of the day begins at Monastery of Varlaam, a remarkable church where it’s easy to get lost in exploration. This top attraction is rated an average of 4.8 out of 5 stars in 6,893 reviews.

Next, satisfy your wanderlust at The Great Meteoron Holy Monastery of the Transfiguration of the Saviour. This place of worship has an average rating of 4.8 out of 5 stars from 8,527 travelers.

Meteora is another must-visit attraction. This renowned monastery offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.9 out of 5 stars by 36,135 travelers, it's one of the more popular places to see in the area.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Thessaloniki. Thessaloniki offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Don’t miss out on dining at Kanoula, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider Extravaganza, another top spot with a mouthwatering menu. You might also want to secure a reservation at Makedonia Palace Hotel. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 6

Day 6 – Thessaloniki - departure day

  • Thessaloniki - Departure day
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  • The Umbrellas by Zongolopoulos
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Day 6 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

As you approach the end of your journey in Greece, take a moment for some retail therapy in Thessaloniki’s celebrated shopping district. Thanks to your stay’s premier location, you can easily visit the city’s commercial hubs and wander through its diverse range of local shops without rushing.

Whether you’re on a hunt for an ideal present to give to your friends or family or looking for a personal memento to remind you of Greece, a variety of items are waiting for you. Hold onto the magic of Greece with these wonderful souvenirs, ensuring your memories never fade.

Make The Umbrellas Sculpture by Zogolopoulos one of your first sightseeing stops in Thessaloniki. Rated an average of 4.7 out of 5 stars by 13,676 travelers, a visit to this local attraction makes for a great introduction to the area.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Dine in style at ARC | espresso • wine bar, a top recommendation for dinner tonight. Or, for a change of pace, Wall by Wall boasts a menu that's sure to impress.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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