11-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling west to Rome, Siena, and Arezzo
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Experience the freedom of the open road in Italy as you embark on an unforgettable 11-day road trip! This experience caters to every traveler, featuring destinations like Perugia, Rome, Siena, and Arezzo.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Perugia, 4 nights in Rome, 2 nights in Siena, and 2 nights in Arezzo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Perugia, Rome, Siena, and Arezzo, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Perugia - Arrival day
- More
- Piazza IV Novembre
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Say hello to Perugia! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Perugia for 1 night before you continue your adventure!
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Iv Novembre, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Perugia. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.
Enjoy a lovely dining experience at Ristorante Settimo Sigillo, a popular restaurant in Perugia. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Perugia at Caffè Baglioni, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Bar Pellas. It’s yet another ideal choice to enhance your time in Perugia tonight.
After enjoying a fulfilling meal, continue your evening at Tommi Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Valentina offers a welcoming atmosphere for easing into the nightlife. Similarly, Caffe Dal Perugino provides an excellent environment for a relaxed and enjoyable evening.
Raise a toast to the start of your 11-day road trip in Italy!
Day 2
- Perugia
- Rome
- More
Drive 184 km, 2 hours 33 min
- Carducci Gardens
- Porta Marzia
- Rocca Paolina
- More
Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Perugia. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 4 nights.
Get ready for a day filled with family-friendly attractions, romantic experiences, and breathtaking views in the charming city of Perugia. Your adventure starts at Carducci Gardens, a curiosity-inducing local hot spot. Another notable attraction to explore is Porta Marzia. This worthwhile monument is known for its romantic appeal.
After soaking in the highlights of these sights, take some time to wander Perugia's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Rocca Paolina. This symbolic historical landmark offers a fascinating experience that many visitors find memorable.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another culinary dining option, venture to Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.
If you’re not ready to end the night just yet, La Botticella Of Poggi Giovanni offers a perfect venue to relax and savor a drink. Similarly, Almalu Trastevere is well-suited for those looking to unwind in a social setting. Bar Viminale Di Pepi Maurilio is another excellent spot to enjoy a nightcap after a delightful meal.
Savor another day of unforgettable experiences in Italy!
Day 3
- Rome
- More
Drive 8 km, 1 hour 2 min
- Trevi Fountain
- Pantheon
- Piazza Navona
- Campo de' Fiori
- Castel Sant'Angelo
- More
On day 3 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 3 nights and discover all the best things to see and do in the area.
Today, you'll explore some of the most beautiful places in Rome, including a monument, a public square, and a castle. Start your day with a visit to Trevi Fountain. This world-famous monument is a must-visit in the city. When you’re ready for your next discovery, continue to Pantheon, which may be one of the most photogenic places you will experience today.
One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Piazza Navona, a world-famous public square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Campo De' Fiori and Castel Sant'angelo.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.
Continue the enjoyment post-dinner at Sant' Eustachio Caffè, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Yellowsquare Rome offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Caffè Portofino. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 4
- Rome
- More
Drive 8 km, 1 hour 14 min
- largo di Torre Argentina
- Altare della Patria
- Roman Forum
- Colosseum
- Basilica di Santa Maria Maggiore
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Day 4 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.
Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Largo Di Torre Argentina. This photogenic archeological site is a highlight of any visit in the city. Then, enjoy Altare Della Patria, another historic attraction that never fails to captivate visitors. Next, head over to Roman Forum, one of the city’s most wondrous attractions, known for its culturally significant features.
If you’re looking for more, spend time soaking in the atmosphere of Colosseum. This UNESCO world heritage-listed archeological site is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Basilica Di Santa Maria Maggiore, a popular church, and take a stroll around the area.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delightful dinner at Hotel de Russie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Taverna Italiana? It's another excellent option with a diverse menu. Consider reserving a table at The Parrot Bar as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.
After your delicious meal, get a taste of the vibrant nightlife with a visit to The Apartment Bar Roma, known for its inviting atmosphere. Hotel Hassler Roma is another great option if you’re looking for a place to get the night started.
Raise your glass to another unforgettable day in Italy!
Day 5
- Rome
- More
Drive 11 km, 1 hour 4 min
- Spanish Steps
- Piazza di Spagna
- piazza del Popolo
- Villa Borghese
- Circus Maximus
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Day 5 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.
Today’s route brings family-friendly attractions, romantic experiences, and breathtaking views. The first attraction of today is Spanish Steps. This impressive public square is an awe-inspiring place to see in Rome. Continue your discovery at Piazza Di Spagna, a romantic public square with stories to tell.
As you stroll around Rome, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Piazza Del Popolo. This top-rated public square offers an enchanting encounter with Rome. Next, make your way to Villa Borghese to add another highlight to your day. After that, visit Circus Maximus, a locally renowned archeological site that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Make sure to reserve a table at Sofitel Roma Villa Borghese, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Centro, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Tema, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Savor another day of unforgettable experiences in Italy!
Day 6
- Rome
- Siena
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Drive 244 km, 3 hours 28 min
- St Peter's Basilica
- Sistine Chapel
- Saint Peter's Square
- Vatican Museums
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Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 2 nights here for some well-deserved relaxation.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Rome allows for both. Start by heading to St. Peter's Basilica. This iconic major basilica provides an insightful glimpse into the city's identity.
Continue your sightseeing with a visit to Saint Peter's Square, an interesting square. When you’re done, don’t forget to make a stop at the globally renowned Vatican Museums.
At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.
Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Round off your dining experience by visiting Meet Life Cafè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Maudit Pub, a bar catering to every mood and preference. Bar Impero Siena likewise offers a unique atmosphere, perfect for a memorable night out.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 7
- Siena
- More
Drive 2 km, 41 min
- Porta Romana
- Pubblico Palace
- piazza del Campo
- Tower of Mangia
- Siena Cathedral
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Day 7 of your road trip across Italy promises a magnificent time exploring Siena. You have 1 night left in Siena. Take the opportunity to experience more of the best attractions and activities in the city.
Brace yourself for today’s incredible lineup of attractions in Siena, featuring fun adventures, breathtaking views, and picturesque spots. Start at Porta Romana, a curiosity-inducing monument in the city. Then, head to Pubblico Palace and soak in the ambiance of this culturally significant palace.
There are many interesting places to see in Siena, and when you are ready for more, go to Piazza Del Campo. This is one of the city’s most spectacular UNESCO world heritage-listed spots of interest. After exploring the public square, visit the worthwhile Tower Of Mangia. Not far away, you'll also find Siena Cathedral. This church is an inviting highlight in Siena.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.
Enjoy a delicious meal at Osteria Quattro Venti, a top-rated dining destination in Siena. If you're in the mood to try something new, consider Fischi per Fiaschi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Osteria da Divo. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Siena this evening.
Following your dinner, dive into the local bar culture at Charlie Mixology Bar Di Aldinucci Riccardo. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bar Pinacoteca, the perfect place for those looking to experience the best of the nightlife. Similarly, San Paolo Pub provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 8
- Siena
- Arezzo
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Drive 74 km, 1 hour 45 min
- Palazzo Salimbeni
- Santuario di Santa Caterina
- Basilica of San Domenico
- Fortezza Medicea
- Porta Camollia, Siena
- More
Dive into day 8 of your remarkable road trip in Italy. Today you will explore Siena, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Arezzo. You’ll stay here for 2 nights.
Immerse yourself in Siena’s rich culture with today's sightseeing itinerary. Start your journey at Palazzo Salimbeni. This photogenic palace is sure to ignite your curiosity. Next, dive into the culturally significant features of Santuario Di Santa Caterina, a must-visit church in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Basilica Of San Domenico, an underrated church. For a change of scene, check out Fortezza Medicea (siena), known for its stunning features. We also recommend visiting Porta Camollia, Siena. This monument is a must for anyone looking to experience the city to the fullest.
When you’re done exploring for the day, you’ll drive to your hotel in Arezzo. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Arezzo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Set out on a gastronomic journey in Arezzo by reserving a table at Octavin. Renowned for its 1-star Michelin recognition, this restaurant presents an outstanding menu of creative cuisine. Looking for something different? La Clandestina offers a tantalizing alternative with its diverse menu. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Arezzo.
Following your dinner, dive into the local bar culture at Liquid Bar. Enjoy this evening's relaxed ambiance with delightful drinks.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 9
- Arezzo
- More
Drive 2 km, 40 min
- Roman Amphitheatre of Arezzo
- San Francesco, Arezzo
- piazza Grande
- The Medici Fortress Park
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On day 9 of your road trip, you will have an entire day to explore Arezzo. You’ll stay in Arezzo for 1 night and discover all the best things to see and do in the area.
Get ready for a day filled with fun adventures, breathtaking views, and picturesque spots in the charming city of Arezzo. Your adventure starts at Roman Amphitheatre Of Arezzo, an up-and-coming local hot spot. Another notable attraction to explore is San Francesco, Arezzo. This beloved church is known for its breathtaking appeal.
After soaking in the highlights of these sights, take some time to wander Arezzo's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza Grande. This history-steeped public square offers a fascinating experience that many visitors find memorable. The Medici Fortress Park is also worth visiting.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Arezzo. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a lovely meal at La Nuova Tagliatella, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, i 3 bicchieri is another top choice with a popular menu. You could also check for a table at Il Cantuccio. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Arezzo tonight.
Head back to your accommodation in Arezzo and get some rest in preparation for another magical day of your road trip in Italy!
Day 10
- Arezzo
- Perugia
- More
Drive 98 km, 1 hour 39 min
- Casa Vasari
- San Domenico
- Arezzo Cathedral
- More
On day 10 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Arezzo. In the evening, you’ll end up in Perugia, where you will stay for 1 night.
Start by visiting Casa Vasari, a prime spot to begin your journey. This respected museum is sure to impress. Next on your list is San Domenico, another must-visit landmark and increasingly popular church renowned for its culturally significant features.
While exploring and sightseeing, take time to savor the culture of Arezzo by sampling some local delicacies. When you’re ready for more sightseeing, head to Arezzo Cathedral. This romantic church is an essential place to visit for anyone looking for the full Arezzo experience.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As dinnertime approaches, it's time to head out for a bite to eat in Perugia. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a delightful dinner at La Taverna, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante del Sole? It's another excellent option with a diverse menu. Consider reserving a table at Al Mangiar Bene as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Perugia.
Explore the vibrant nightlife at Caffè Fortebraccio after your meal, a hub for lively evenings and memorable moments. Or, head to Caffe Del Banco for a great selection of flavorful drinks and a charming setting. Furthermore, Dempsey's Perugia is perfect for those looking to extend their night with a touch of local flavor.
Raise your glass and celebrate another amazing day of your road trip in Italy!
Day 11
- Perugia - Departure day
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- Etruscan Arch
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Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Etruscan Arch. This increasingly popular historical landmark is a popular place to see in the city.
As your final day in Italy unfolds, enjoy a last-minute shopping spree in Perugia's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Italy.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
If you're in the mood for something new, try Elfo Pub Perugia, another premier location with a delectable menu.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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