12-Day Italy Road Trip from Naples to Viterbo, Florence, Siena, and Rome

Day 2 offers a multitude of experiences. You will stay in Naples for 1 night more, offering you enough time to explore at a relaxed pace.

When you’re ready for some sightseeing, make your way to Castel Sant'elmo. This much-appreciated castle is rated 4.6 out of 5 stars in 25,314 reviews.

Next up is Napoli Sotterranea Percorso Ufficiale. This museum has an average rating of 4.6 out of 5 stars from 19,274 visitors.

Another top sightseeing recommendation is Cappella Sansevero. This former church has been rated 4.7 out of 5 stars in 25,405 reviews. Every year, 175,138 travelers include this attraction on their travel itinerary.

Chiesa Del Gesù Nuovo is another attraction you have the opportunity to visit today. This church has an average rating of 4.6 out of 5 stars from 16,437 reviews.

There are plenty of experiences you can choose from in Italy that will add excitement to your vacation. When you’re keen to discover what else Naples has in store for you, use this day to go on a tour. Scroll down and select tours and activities to include on your itinerary for the day.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to an extraordinary dining experience at Veritas, a 1-star Michelin restaurant offering an incredible campanian, and contemporary menu. Alternatively, if your taste buds call for something different, Il Comandante is one of the best restaurants for creative, and mediterranean cuisine in Naples. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at ARIA. As a top-rated establishment with 1 Michelin star, it is an ideal choice for contemporary, and modern cuisine in the city.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Archivio Storico - Cocktail Bar & Wonderfood, known for its inviting atmosphere. Babette Pub is another great option if you’re looking for a place to get the night started. Similarly, Gran Caffè Cimmino provides a great setting to enjoy the night away.

Raise your glass to another unforgettable day in Italy!

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Orvieto. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Continue your road trip and head to your next destination, Orvieto. This car ride takes around 53 min.

Begin your sightseeing with a visit to Orvieto Cathedral. This catholic cathedral is rated an average of 4.8 out of 5 stars in 15,057 reviews.

Next up, make your way to Orvieto Underground. This archaeological site has an average rating of 4.6 out of 5 stars from 1,517 reviews. Usually, around 37,000 people visit Orvieto Underground every year.

Embrace the thrill of the open road as you wave goodbye to Viterbo and set your GPS to Orvieto. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 53 min. Upon reaching Orvieto, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you’re ready for some sightseeing, make your way to Well Of St. Patrick. This much-appreciated sightseeing destination is rated 4.5 out of 5 stars in 14,274 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a memorable dining experience in Florence by booking a table at Enoteca Pinchiorri, renowned as a 3-star Michelin restaurant presenting an exceptional italian contemporary menu. For a different culinary experience in Florence, Santa Elisabetta shines as one of the top destinations, known for its delicious creative, and mediterranean cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Gucci Osteria da Massimo Bottura is known as a top local spot for its delicious italian contemporary, and international cuisine in Florence. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Manifattura, a well-loved spot among locals and tourists. Or, head to Se·sto On Arno Rooftop Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Archea Brewery, another top-rated place in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 5 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

An excellent attraction to start your day with is Piazzale Michelangelo. This square is rated an average of 4.8 out of 5 stars in 77,744 reviews.

Continue your journey at Uffizi Gallery. This national museum is rated 4.7 out of 5 stars by 61,794 travelers from near and far. Approximately 2,011,219 people come to this place of interest every year to enjoy a unique experience in Florence.

Florence is also the home of Ponte Vecchio. This deck arch bridge has an average rating of 4.7 out of 5 stars from 118,099 visitors.

You can continue your self-guided sightseeing tour at Palazzo Vecchio. Rated 4.7 out of 5 stars by 19,049 visitors, a visit to this top sight is time well spent.

Lastly, don't miss out on Piazza Della Signoria. With an average rating of 4.8 out of 5 stars from 66,956 reviews, it’s hard to refuse the opportunity to see this square.

Don’t forget to check out all the popular tours and activities you can add to your travel plan. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Savor the flavors at Trattoria Da Burde, a top pick for dinner tonight. Alternatively, Ristorante Buca Mario beckons with its unique menu offerings. Also, consider Eataly Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Take some time to reflect on your day and savor another beautiful night in Italy.

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Florence, and Pisa, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.

When you’re ready for some sightseeing, make your way to Cathedral Of Santa Maria Del Fiore. This much-appreciated church is rated 4.8 out of 5 stars in 76,359 reviews.

Next up is Central Market. This point of interest has an average rating of 4.4 out of 5 stars from 43,100 visitors.

Continue your road trip and head to your next destination, Pisa. This car ride takes around 1 hour 18 min.

Drop by the renowned Leaning Tower Of Pisa. This popular bell tower has been rated an average of 4.7 out of 5 stars by 116,882 visitors. Based on recent data, this attraction is visited by more than 3,200,000 travelers every year.

Another unforgettable place to experience is Piazza Del Duomo, Pisa. Rated 4.7 out of 5 stars by 104,550 visitors, this square deserves a spot on today's sightseeing itinerary.

When you’re done exploring for the day, you’ll drive to Siena, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Antica Trattoria Papei, a highly-rated dining destination in Siena. If you're eager to try something different, consider Osteria Quattro Venti, another top spot with a tantalizing menu. You might also want to secure a reservation at Osteria da Divo. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Siena this evening.

After savoring a delicious meal, step into the vibrant nightlife at Meet Life Cafè, where the evening is just getting started. In the same way, Maudit Pub offers a unique charm perfect for experiencing the local bar scene in Siena. Bar Impero Siena is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Take some time to reflect on your day and savor another beautiful night in Italy.

Embark on another extraordinary experience on day 7 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 4 nights.

As you’ve unraveled the marvels of Siena, it’s time to gear up for the next part of your road trip adventure. Set course for Vatican City! Under favorable conditions, your drive to Vatican City may take around 2 hours 37 min. Upon your arrival in Vatican City, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Begin your sightseeing with a visit to Vatican Museums. This extraordinary art museum is rated an average of 4.6 out of 5 stars by 133,310 visitors. Each year, around 1,612,530 people visit this site to learn more about it.

Next, make your way to Sistine Chapel. This top attraction is a chapel with an average rating of 4.7 out of 5 stars by 52,083 visitors.

We also recommend a visit to St. Peter's Basilica. Hosting 11,000,000 visitors every year, St. Peter's Basilica is one of the most popular places to visit in Vatican City. This major basilica is rated 4.8 out of 5 stars by 131,043 travelers.

If you’re keen to keep exploring, visit Saint Peter's Square. This highly recommended sightseeing destination has received an average rating of 4.8 out of 5 stars from 38,954 travelers.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Get ready for an unforgettable culinary journey in Rome by reserving a table at La Pergola. Renowned as a 3-star Michelin restaurant, it offers an exceptional mediterranean, and contemporary menu. For a different taste experience, head to Il Pagliaccio, recognized for its delicious creative, and innovative dishes. This 2-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Enoteca La Torre, a local favorite known for its delightful mediterranean, and creative cuisine in Rome. Nestled in the heart of the city, this restaurant with 2 Michelin star is an ideal choice for discerning mediterranean, and creative foodies seeking culinary excellence.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Sant' Eustachio Caffè, a bar that offers unique local touches. Likewise, Caffè Portofino provides an excellent alternative for a fun evening.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Day 8 of your road trip will take you to the best attractions Rome has to offer. Cherish the 3 nights you have left in Rome by discovering the best things there are to see and do in the city.

Begin your sightseeing with a visit to Circus Maximus. This extraordinary circus is rated an average of 4.4 out of 5 stars by 44,741 visitors.

Next, make your way to Colosseum. This top attraction is a roman amphitheatre with an average rating of 4.7 out of 5 stars by 328,821 visitors. Colosseum welcomes 7,400,000 yearly visitors.

We also recommend a visit to Roman Forum. This square is rated 4.7 out of 5 stars by 114,450 travelers.

If you’re keen to keep exploring, visit Pantheon. This highly recommended sightseeing destination has received an average rating of 4.8 out of 5 stars from 189,682 travelers. Around 30,000,000 people come to experience this place of interest every year.

Today is also your chance to spend some time at Piazza Navona. This square is rated an average of 4.7 out of 5 stars by 158,771 travelers.

If you have an appetite for more adventure, check out the fantastic selection of tours and tickets offered in Rome on this day of your trip. You'll find the most recommended ones below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at DEROMA - Farine Romane, a top-rated dining spot in Rome. If you're in the mood for something new, try La Taverna Italiana, another premier location with a delectable menu. You might also want to book a table at Centro. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Round off your dining experience by visiting The Apartment Bar Roma, a prime location for a drink. Alternatively, explore the distinctive characteristics of Hotel Hassler Roma, a bar catering to every mood and preference.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

Day 9 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Make Trevi Fountain one of your first sightseeing stops in Rome. Rated an average of 4.8 out of 5 stars by 343,494 travelers, a visit to this local attraction makes for a great introduction to the area.

Spanish Steps is a worthwhile attraction you can visit next. This monumental staircase is a valued place of interest in the area, with an average rating of 4.5 out of 5 stars from 57,211 reviews.

Today is also the perfect opportunity to drop by Piazza Di Spagna. This square has been rated an average of 4.7 out of 5 stars by 113,658 visitors.

If you’re keen to explore more, head to Piazza Del Popolo. A trip to this popular square is also your opportunity to see if it lives up to the reputable 4.6 out of 5-star rating as given by 89,807 previous visitors.

Another top place to visit is Villa Borghese. This urban zone of rome enjoys an average rating of 4.6 out of 5 stars from 69,749 local and international travelers.

One of the most unique ways of discovering what else Rome has to offer is by going on a top-rated tour. Be sure to check out all the experiences Rome offers and add your favorites to your Italy travel package below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at Ristorante Tema, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Maccheroni, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of RoYaL Art Cafè Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 10 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

Be one of the day’s first visitors at Basilica Di Santa Maria Maggiore. This major basilica is rated an average of 4.8 out of 5 stars by 27,678 visitors.

When you’re finished at Basilica Di Santa Maria Maggiore, head to Castel Sant'angelo. This one-of-a-kind museum is rated an average of 4.7 out of 5 stars in 72,431 reviews. Every year, approximately 918,591 travelers come here to experience the museum for themselves.

Beyond the above-mentioned attractions, you also have the opportunity to visit Campo De' Fiori. This square is rated an average of 4.4 out of 5 stars by 51,133 visitors.

If you’re keen to explore more, then consider a visit to Largo Di Torre Argentina. This square is a much-appreciated attraction with an average rating of 4.5 out of 5 stars from 30,433 visitors.

To round off your sightseeing experience, make your way to Altare Della Patria. This famous architectural structure welcomes around 1,683,070 visitors annually and is rated an average of 4.8 out of 5 stars by 49,843 travelers.

Immerse yourself in the local scene through top-rated tours and activities. You can choose from a wide variety of easy to challenging tours and easily add them to your travel package below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Harry's Bar, a highly-rated dining destination in Rome. If you're eager to try something different, consider Ristorante Amedeo, another top spot with a tantalizing menu. You might also want to secure a reservation at VinAllegro. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Rome this evening.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Caserta, and Pompei. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 1 night here for some well-deserved relaxation.

Fasten your seatbelt and make your way to your next stop. Caserta, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Rome to Caserta may take around 2 hours 15 min without traffic disruptions. Upon arrival in Caserta, we highly recommend checking out some of the top attractions.

Take the opportunity to see Palace Of Caserta. This attraction has an average rating of 4.6 out of 5 stars from 36,840 visitors and gets around 296,577 visits every year.

Giardini Reali - Parco Reggia Di Caserta is another sightseeing hotspot in the area. This sightseeing destination has been rated an average of 4.7 out of 5 stars by 18,740 travelers.

When you’ve had your share of Caserta, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pompei. Your travel time is around 43 min.

Begin your sightseeing with a visit to Archaeological Park Of Pompeii. This museum is rated an average of 4.7 out of 5 stars in 49,465 reviews.

Next up, make your way to Teatro Grande. This sightseeing destination has an average rating of 4.7 out of 5 stars from 5,226 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Naples. Naples offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Make sure to reserve a table at Amoroso dal 1876 - Ristorante e Pizzeria Napoli, an iconic dining spot in Naples. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Vittoria Black & White St. John, a popular restaurant in Naples. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antichi Sapori Partenopei Restaurant, a hidden gem nestled in Naples. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Let the evening flow smoothly from dinner to drinks at Flanagan's Bar, a top-rated bar in the area. For other recommendations, Parthenope Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Gianni Unica Sede Dal 1970 offers a memorable night with diverse drink options and excellent service.

Say good night to Naples and look forward to another great day of your road trip in Italy!