12-Day Italy Road Trip from Rome traveling north to Siena, Florence, and Perugia

Day 2 of your road trip will take you to the best attractions Rome has to offer. Cherish the 3 nights you have left in Rome by discovering the best things there are to see and do in the city.

Drop by the renowned Colosseum. This popular roman amphitheatre has been rated an average of 4.7 out of 5 stars by 328,821 visitors. Based on recent data, this attraction is visited by more than 7,400,000 travelers every year.

Another unforgettable place to experience is Roman Forum. Rated 4.7 out of 5 stars by 114,450 visitors, this square deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Pantheon. Hosting around 30,000,000 visitors every year, the fascinating Pantheon is one of the best places to visit in Rome. This roman temple has been rated an average of 4.8 out of 5 stars in 189,682 reviews.

Another favorite attraction in the area is Piazza Navona. This square and popular place of interest enjoys a rating of 4.7 out of 5 stars from 158,771 local and international travelers.

If you’re keen to explore even more, then consider a visit to Castel Sant'angelo. This museum gets around 918,591 annual visitors. With an average rating of 4.7 out of 5 stars from 72,431 travelers, this museum is an attraction many avid travelers highly recommend visiting while in Rome.

You can learn more about Rome today by going on a tour. Rome offers many top-rated tours and unique experiences that will inspire you. You can browse and select your favorites below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Experience a symphony of flavors at La Pergola in Rome by securing a reservation in advance. Renowned for its 3-star Michelin distinction, La Pergola delights its guests with its exceptional variety of meals showcasing delicious mediterranean, and contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Il Pagliaccio, acclaimed for its delectable creative, and innovative specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Enoteca La Torre, a top-rated restaurant known for its outstanding menu. Known as a top-rated 2-star Michelin establishment, it's a top choice for mediterranean, and creative cuisine in the city.

To truly maximize your evening out, consider visiting The Apartment Bar Roma after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hotel Hassler Roma, another bar with an inviting ambiance.

Relax and recharge in preparation for another adventurous day in Italy!

Day 3 offers a multitude of experiences. You will stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.

Begin your sightseeing with a visit to Trevi Fountain. This extraordinary sculpture is rated an average of 4.8 out of 5 stars by 343,494 visitors.

Next, make your way to Piazza Di Spagna. This top attraction is a square with an average rating of 4.7 out of 5 stars by 113,658 visitors.

We also recommend a visit to Spanish Steps. This monumental staircase is rated 4.5 out of 5 stars by 57,211 travelers.

If you’re keen to keep exploring, visit Piazza Del Popolo. This highly recommended sightseeing destination has received an average rating of 4.6 out of 5 stars from 89,807 travelers.

Today is also your chance to spend some time at Villa Borghese. This urban zone of rome is rated an average of 4.6 out of 5 stars by 69,749 travelers.

If you have an appetite for more adventure, check out the fantastic selection of tours and tickets offered in Rome on this day of your trip. You'll find the most recommended ones below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Ristorante Tema, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Maccheroni is another top choice with a popular menu. You could also check for a table at RoYaL Art Cafè Roma. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

Get a good night's sleep and look forward to another great day on the road in Italy!

Wake up to day 4 of your extraordinary road trip in Italy. With 1 night left in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’ve had your share of Rome, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Vatican City, Vatican City. Your travel time is around 11 min.

An excellent attraction to start your day with is St. Peter's Basilica. This major basilica typically receives around 11,000,000 visitors every year and is rated an average of 4.8 out of 5 stars in 131,043 reviews.

Continue your journey at Sistine Chapel. This chapel is rated 4.7 out of 5 stars by 52,083 travelers from near and far.

Vatican City is also the home of Saint Peter's Square. This square has an average rating of 4.8 out of 5 stars from 38,954 visitors.

You can continue your self-guided sightseeing tour at Vatican Museums. A total of 1,612,530 people explore this attraction every year. Rated 4.6 out of 5 stars by 133,310 visitors, a visit to this top sight is time well spent.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at Harry's Bar, a top pick for dinner tonight. Alternatively, Ristorante Amedeo beckons with its unique menu offerings. Also, consider VinAllegro. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Raise your glass to another unforgettable day in Italy!

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Orvieto. In the evening, you’ll end up in Siena, where you will stay for 1 night.

Fasten your seatbelt and make your way to your next stop. Orvieto, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Rome to Orvieto may take around 1 hour 38 min without traffic disruptions. Upon arrival in Orvieto, we highly recommend checking out some of the top attractions.

When you’re ready for some sightseeing, make your way to Orvieto Cathedral. This much-appreciated catholic cathedral is rated 4.8 out of 5 stars in 15,057 reviews.

Next up is Museo Dell'opera Del Duomo. This art museum has an average rating of 4.5 out of 5 stars from 238 visitors. As one of the top places to visit in the town, Museo Dell'opera Del Duomo welcomes 37,892 visitors annually.

Another top sightseeing recommendation is Orvieto Underground. This archaeological site has been rated 4.6 out of 5 stars in 1,517 reviews. Every year, 37,000 travelers include this attraction on their travel itinerary.

When you’ve had your share of Rome, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Orvieto. Your travel time is around 1 hour 38 min.

Begin your sightseeing with a visit to Well Of St. Patrick. This extraordinary point of interest is rated an average of 4.5 out of 5 stars by 14,274 visitors.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you explore more of Siena, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Antica Trattoria Papei, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Osteria Quattro Venti? It's another excellent option with a diverse menu. Consider reserving a table at Osteria da Divo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

Let the evening flow smoothly from dinner to drinks at Meet Life Cafè, a top-rated bar in the area. For other recommendations, Maudit Pub provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Impero Siena offers a memorable night with diverse drink options and excellent service.

Raise your glass to another unforgettable day in Italy!

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Siena, and Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 4 nights.

When you're ready to see some sights, Tower Of Mangia is a great place to start. This sightseeing destination is rated an average of 4.6 out of 5 stars by 673 visitors.

Another popular attraction you can visit today is Piazza Del Campo. This square has an average rating of 4.8 out of 5 stars from 64,175 travelers.

We also recommend a stop at Siena Cathedral. The domus has been rated an average of 4.8 out of 5 stars by 21,656 visitors.

Pisa’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Siena behind. This drive usually takes around 1 hour 48 min. Pisa welcomes you with a multitude of unique vacation experiences.

Drop by the renowned Piazza Del Duomo, Pisa. This popular square has been rated an average of 4.7 out of 5 stars by 104,550 visitors.

Another unforgettable place to experience is Leaning Tower Of Pisa. Rated 4.7 out of 5 stars by 116,882 visitors, this bell tower deserves a spot on today's sightseeing itinerary.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative, and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gucci Osteria da Massimo Bottura. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary, and international cuisine in the city.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 7 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 3 nights and discover all the best things to see and do in the area.

Be one of the day’s first visitors at Piazza Della Signoria. This square is rated an average of 4.8 out of 5 stars by 66,956 visitors.

When you’re finished at Piazza Della Signoria, head to Palazzo Vecchio. This one-of-a-kind palazzo is rated an average of 4.7 out of 5 stars in 19,049 reviews.

Beyond the above-mentioned attractions, you also have the opportunity to visit Uffizi Gallery. This national museum is rated an average of 4.7 out of 5 stars by 61,794 visitors. Visiting Uffizi Gallery means you'll be one of 2,011,219 people who do so every year.

If you’re keen to explore more, then consider a visit to Ponte Vecchio. This deck arch bridge is a much-appreciated attraction with an average rating of 4.7 out of 5 stars from 118,099 visitors.

To round off your sightseeing experience, make your way to Piazzale Michelangelo. This famous square is rated an average of 4.8 out of 5 stars by 77,744 travelers.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Trattoria Da Burde, an excellent option for tonight's dining. Looking for something different? Ristorante Buca Mario offers a tantalizing alternative with its diverse menu. And don’t miss Eataly Firenze. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

Take some time to reflect on your day and savor another beautiful night in Italy.

Day 8 of your road trip across Italy promises a magnificent time exploring Florence. You have 2 nights left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Journey into the unknown at Cathedral Of Santa Maria Del Fiore, a unique attraction awaiting your visit. This remarkable church has an average rating of 4.8 out of 5 stars from 76,359 reviews.

When you’re ready to continue your sightseeing, Central Market is a recommended place to visit. This point of interest is rated an average of 4.4 out of 5 stars in 43,100 reviews.

Another must-see attraction in Florence is Brunelleschi's Dome. Rated an average of 4.8 out of 5 stars by 6,199 travelers, this popular tourist destination in Florence offers an experience you will remember.

David is another popular stop on travelers' itineraries in Florence. This statue promises memorable moments of exploring. Other travelers have rated this attraction 4.8 out of 5 stars in 10,476 reviews.

Lastly, don't miss out on Galleria Dell'accademia. Rated 4.6 out of 5 stars by 34,429 local and international travelers, it's a popular place to visit. This national museum gets closer to 1,719,645 visits every year.

Immerse yourself in the local scene through top-rated tours and activities. You can choose from a wide variety of easy to challenging tours and easily add them to your travel package below.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a wonderful meal at Tijuana, a top-rated dining spot in Florence. If you're in the mood for something new, try Djària - American Bar, another premier location with a delectable menu. You might also want to book a table at Ristorante Buca Niccolini. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Raise your glass to another unforgettable day in Italy!

Day 9 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in Florence by discovering the best things there are to see and do in the city.

When you're ready to see some sights, Basilica Di Santa Maria Novella, Firenze (fi) is a great place to start. This archives is rated an average of 4.7 out of 5 stars by 23,075 visitors.

Another popular attraction you can visit today is Basilica Of Santa Croce In Florence. This church has an average rating of 4.7 out of 5 stars from 28,544 travelers.

We also recommend a stop at Pitti Palace. This site gets more than 198,270 visitors annually. The art museum has been rated an average of 4.6 out of 5 stars by 23,445 visitors.

If you're keen to explore more, consider visiting The Boboli Gardens. This park is a popular attraction with an average rating of 4.2 out of 5 stars from 25,341 reviews.

One of the most unique ways of discovering what else Florence has to offer is by going on a top-rated tour. Be sure to check out all the experiences Florence offers and add your favorites to your Italy travel package below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Cibrèo Caffè, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Ristorante Le Volte Firenze, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Romantico il Paiolo. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Florence this evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Dive into day 10 of your remarkable road trip in Italy. Today you will explore Perugia, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Perugia. You’ll stay here for 1 night.

Set your GPS to Perugia and hit the road. Expect a journey of approximately 1 hour 56 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Perugia beckons with new experiences!

A top pick for your self-guided sightseeing tour today is Perugia Cathedral. Previous visitors have rated this cathedral an average of 4.6 out of 5 stars in 1,282 reviews.

Piazza Iv Novembre is a local recommendation that you also can pay a visit today. This square is rated an average of 4.6 out of 5 stars in 9,189 reviews.

Another attraction you won't want to miss is National Gallery. This museum is rated an average of 4.6 out of 5 stars in 1,294 reviews.

When you’re done exploring for the day, you’ll drive to Perugia, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.

Enjoy a delicious meal at Ristorante Settimo Sigillo, a highly-rated dining destination in Perugia. If you're eager to try something different, consider Bar Pellas, another top spot with a tantalizing menu. You might also want to secure a reservation at La Taverna. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Perugia this evening.

To truly maximize your evening out, consider visiting Tommi Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Valentina, another bar with an inviting ambiance. Similarly, Caffe Dal Perugino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Celebrate another amazing day of your road trip adventure in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Perugia, Collestatte, and Tiro a Segno. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 1 night here for some well-deserved relaxation.

Begin your sightseeing with a visit to Carducci Gardens. This extraordinary park is rated an average of 4.5 out of 5 stars by 1,768 visitors.

Next, make your way to Rocca Paolina. This top attraction is a rocca with an average rating of 4.7 out of 5 stars by 7,128 visitors.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Collestatte. This drive usually takes around 1 hour 11 min, without any stops or traffic disruptions.

Journey into the unknown at Parco Fluviale Del Nera, a unique attraction awaiting your visit. This remarkable park has an average rating of 4.7 out of 5 stars from 15,518 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Cantina e Cucina, a top pick for dinner tonight. Alternatively, Bono Bottega Nostrana - Piazza Di Spagna beckons with its unique menu offerings. Also, consider Ai Tre Scalini. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Say good night to Rome and look forward to another great day of your road trip in Italy!