12-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling south to Naples, Cosenza, and Salerno

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Photo of piazza de spagna in Rome, Italy.
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Explore the best of Italy on a remarkable 12-day road trip! Combine exploration with relaxation on a self-drive tour featuring Rome, Gaeta, Naples, Ercolano, Pompei, Cosenza, Morano Calabro, Ravello, Amalfi, Salerno, Caserta, San Leucio-complex, and Tivoli.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 6 nights in Rome, 3 nights in Naples, 1 night in Cosenza, and 1 night in Salerno. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Gaeta, Naples, Ercolano, Pompei, Cosenza, Morano Calabro, Ravello, Amalfi, Salerno, Caserta, San Leucio-complex, and Tivoli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Rome - Arrival day
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  • Trevi Fountain
  • More

Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay here for 5 nights and explore what to see in Rome, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Trevi Fountain. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Rome. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at La Bottega Roma, a highly-rated dining destination in Rome. If you're eager to try something different, consider Pasta In Corso, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise a toast to the start of your 12-day road trip in Italy!

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Day2

Day 2

  • Rome
  • More

Drive 8 km, 1 hour 9 min

  • Spanish Steps
  • Piazza di Spagna
  • Pantheon
  • Roman Forum
  • Colosseum
  • More

Day 2 of your road trip will take you to the best attractions Rome has to offer. Cherish the 4 nights you have left in the city and use the provided itinerary to discover what to see in Rome.

Experience Spanish Steps, an astonishing public square in the city. Then, head to Piazza Di Spagna and soak in the ambiance of this visually striking public square.

There are many interesting places to see in Rome, and when you are ready for more, go to Pantheon. This is one of the city’s most timeless culturally significant spots of interest. After exploring the monument, visit the timeless Roman Forum. Not far away, you'll also find Colosseum. This archeological site is a historic highlight in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Prepare for an extraordinary culinary adventure in Rome by booking a table at La Pergola, a 3-star Michelin restaurant that boasts an exceptional mediterranean and contemporary menu. For a different flavor experience, head to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This 2-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Enoteca La Torre, a local gem known for its delightful mediterranean and creative cuisine in Rome. Nestled in the city's heart, this 2-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Keep the evening going at Sant' Eustachio Caffè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Yellowsquare Rome, which offers a similarly pleasant setting and great drinks. Another option is Caffè Portofino, which provides an inviting environment for unwinding after a busy day out.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day3

Day 3

  • Rome
  • More

Drive 10 km, 1 hour 7 min

  • Villa Borghese
  • piazza del Popolo
  • Castel Sant'Angelo
  • Piazza Navona
  • Campo de' Fiori
  • More

Day 3 offers an itinerary packed with the best things to see in Rome. You’ll stay in Rome for 3 nights more, offering you enough time to explore at a relaxed pace.

No visit to Rome is complete without Villa Borghese. This widely recognized park is one of the top attractions in the city. Proceed to Piazza Del Popolo, another must-visit attraction.

As you wander through the inviting streets of Rome, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Castel Sant'angelo. This astonishing castle is a traveler-favorite. Not far away, you’ll find Piazza Navona, another key site on your sightseeing itinerary. Campo De' Fiori is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at The Apartment Bar Roma, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Hotel Hassler Roma offers a vibrant space for indulging in well-crafted drinks and engaging conversation.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Rome
  • More

Drive 11 km, 59 min

  • St Peter's Basilica
  • Sistine Chapel
  • Saint Peter's Square
  • Vatican Museums
  • More

On day 4 of your road trip, you’ll start and end your day in Rome, where you still have 2 nights left. You'll spend part of the day exploring places of interest outside the immediate city, including Vatican City.

Vatican City is brimming with adventures.

St. Peter's Basilica is must-visit major basilica and a great option for a daytime tour of the area. Continue your journey to Sistine Chapel, an impressive chapel, located just a leisurely stroll away.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Dine in style at Sofitel Roma Villa Borghese, a top recommendation for dinner tonight. Or, for a change of pace, Centro boasts a menu that's sure to impress. Also, be sure to check out Ristorante Tema. Known as a local hotspot, it’s a great choice for tonight in Rome.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day5

Day 5

  • Rome
  • More

Drive 290 km, 4 hours 47 min

  • Castello Angioino-Aragonese
  • Gaeta Medievale
  • Piana Di Sant'Agostino
  • More

On day 5 of your road trip, you'll get the chance to experience Gaeta. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

Castello Angioino-aragonese makes a great addition to your morning plans. This up-and-coming castle is a visually striking place to see in Rome. Continue your discovery at Gaeta Medievale, a visually striking historical landmark with stories to tell.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Piana Di Sant'agostino. This curiosity-inducing beach offers a serene encounter with Rome. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a delicious meal at Ristorante Va. Do. , a top-rated dining destination in Rome. If you're in the mood to try something new, consider Giulia Restaurant, another top spot with a mouthwatering menu. You might also want to secure a reservation at L'Archeologia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Savor another day of unforgettable experiences in Italy!

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Day6

Day 6

  • Rome
  • Naples
  • More

Drive 253 km, 4 hours 14 min

  • Sanctuary of Montagna Spaccata
  • Parco Monte Orlando
  • Ulisse
  • More

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Gaeta. When you’re not sightseeing, take time to relax at your chosen hotel in Naples, where you’ll be staying for 3 nights.

Sanctuary Of Montagna Spaccata is an ideal stop early in the day. This intriguing church is a must-visit in the town. When you’re ready for your next discovery, continue to Parco Monte Orlando, which may be one of the most eye-catching places you will experience today.

One of the best things about exploring Rome on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Ulisse, an intriguing park in the town.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Naples is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Naples.

Get ready for an unforgettable culinary journey in Naples by reserving a table at Veritas. Renowned as a 1-star Michelin restaurant, it offers an exceptional campanian and contemporary menu. For a different taste experience, head to Il Comandante, recognized for its delicious creative and mediterranean dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit ARIA, a local favorite known for its delightful contemporary and modern cuisine in Naples. Nestled in the heart of the city, this restaurant with 1 Michelin star is an ideal choice for contemporary and modern foodies seeking culinary excellence.

After savoring a delicious meal, step into the vibrant nightlife at Happening Cocktail Bar, where the evening is just getting started. In the same way, Shanti Art Musik Bar offers a unique charm perfect for experiencing the local bar scene in Naples. Gran Caffè Gambrinus is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day7

Day 7

  • Naples
  • More

Drive 5 km, 1 hour 18 min

  • Ovo Castle
  • piazza del Plebiscito
  • San Carlo Theatre
  • Castel Nuovo
  • Chiesa del Gesù Nuovo
  • More

On day 7 of your road trip, you will have an entire day to discover what to see in Naples. You’ll stay in Naples for 2 nights.

Visiting Ovo Castle is always a good idea. This interesting castle is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the respected wonders of Piazza Del Plebiscito, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to San Carlo Theatre. This worthwhile opera house offers an enriching experience. For a change of pace, head to Castel Nuovo, where you can take in culturally significant features. Conclude your self-guided sightseeing tour with a visit to Chiesa Del Gesù Nuovo These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Antica Pizzeria Di Matteo, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Mercure Napoli Centro Angioino, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Lazzara Trattoria e Pizzeria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Naples this evening.

Cap off your dinner by heading to Archivio Storico - Cocktail Bar & Wonderfood, ideal for a leisurely evening with a drink in hand. Archeobar is another bar that offers an enjoyable setting. Similarly, Babette Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another amazing day of your road trip adventure in Italy!

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Day8

Day 8

  • Naples
  • More

Drive 7 km, 41 min

  • Cattedrale di Santa Maria Assunta
  • Napoli Sotterranea Percorso Ufficiale
  • Cappella Sansevero
  • Naples National Archaeological Museum
  • More

Day 8 of your road trip across Italy promises a magnificent time exploring what to see in Naples. You have 1 night left in Naples. Take the opportunity to experience more of the best attractions and activities in the city.

To truly experience Naples, make sure to drop by Cattedrale Di Santa Maria Assunta. This locally renowned church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Napoli Sotterranea Percorso Ufficiale, one of the city’s best highlights.

Next, check out Cappella Sansevero, one of the most well-known places to see in Naples. This museum is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Naples National Archaeological Museum. Wander around and soak in the heritage-rich atmosphere this museum offers.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Opera Restaurant, a top-rated dining spot in Naples. If you're in the mood for something new, try Trattoria San Ferdinando, another premier location with a delectable menu. You might also want to book a table at Anonymous Trattoria Gourmet. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Naples.

If you’re not ready to end the night just yet, Gran Caffè Cimmino offers a perfect venue to relax and savor a drink. Similarly, Flanagan's Bar is well-suited for those looking to unwind in a social setting. Bar Napoli is another excellent spot to enjoy a nightcap after a delightful meal.

Head back to your accommodation in Naples and get some rest to prepare for another magical day of your road trip in Italy.

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Day9

Day 9

  • Naples
  • Cosenza
  • More

Drive 340 km, 4 hours 24 min

  • Archaeological Park of Herculaneum
  • Vesuvio National Park
  • Archaeological Park of Pompeii
  • More

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Ercolano and Pompei. At the end of the day, you will retreat to the hotel of your choice in Cosenza, where will spend 1 night.

Experience Archaeological Park Of Herculaneum, a frequently visited archeological site in the town. Then, head to Vesuvio National Park and soak in the ambiance of this history-steeped national park.

There are many interesting places to see in Naples, and when you are ready for more, go to Archaeological Park Of Pompeii. This is one of the town’s most notable UNESCO world heritage-designated spots of interest.

When you’re done exploring for the day, you’ll drive to your hotel in Cosenza. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Cosenza. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Osteria San Lorenzo, an iconic dining spot in Cosenza. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Il Paesello, a popular restaurant in Cosenza. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Hippocampus, a hidden gem nestled in Cosenza. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, 1930 stands out as an excellent choice for a post-dinner cocktail. Alternatively, La Bodega offers an ideal atmosphere to enjoy the pleasures of the night. People Pub is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!

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Day10

Day 10

  • Cosenza
  • Salerno
  • More

Drive 338 km, 5 hours 5 min

  • Lavenda Park
  • Villa Rufolo
  • Amalfi Coast
  • Cattedrale di Santa Maria degli Angeli, San Matteo e San Gregorio VII
  • More

Dive into day 10 of your remarkable road trip in Italy. Today you'll explore 4 destinations, including Morano Calabro, Ravello, Amalfi, and Salerno. At the end of the day, you’ll unwind at one of the finest accommodations in Salerno, where you'll spend 1 night.

Check out the locally appreciated park, Lavenda Park. Afterward, continue to Villa Rufolo, a historical landmark every traveler should visit. As you explore Cosenza’s charming streets, take in the lively atmosphere and get to know the character of the city.

Next, make your way to Amalfi Coast. This extraordinary coast is an essential stop. Following that, head to Cathedral Of Santa Maria Degli Angeli, San Matteo And San Gregorio Vii, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Salerno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Salerno. Enjoy a relaxing evening as you savor delicious local cuisine.

Dive into a culinary adventure like no other in Salerno by booking a table at Re Maurì. This popular restaurant holds 1 Michelin star and offers an exceptional menu of creative cuisine. If you're in the mood to try something new, consider L'Unico Drink & Food Salerno, another top spot with a mouthwatering menu.

Explore the vibrant nightlife at Hilton Bar E Gastronomia after your meal, a hub for lively evenings and memorable moments. Or, head to The Black Monday Speakeasy Tbm for a great selection of flavorful drinks and a charming setting. Furthermore, Dòmo I' Vinaino Wine Bar - Enogastronomia is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Salerno and look forward to another great day of your road trip in Italy!

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Day11

Day 11

  • Salerno
  • Rome
  • More

Drive 305 km, 4 hours 12 min

  • Palace of Caserta
  • Giardini Reali - Parco Reggia di Caserta
  • Complesso Monumentale Belvedere San Leucio
  • Villa d'Este
  • More

Your itinerary for day 11 of your road trip in Italy includes 3 stops and features some of the highlights of Caserta, San Leucio-complex, and Tivoli. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

Whatever your travel style is, Palace Of Caserta is an essential stop in Salerno. This captivating palace provides an insightful glimpse into the city's identity. Next, discover Giardini Reali - Parco Reggia Di Caserta, a visually striking park, promising a delightful encounter.

Continue your sightseeing with a visit to Complesso Monumentale Belvedere San Leucio, a beloved museum. When you’re done, don’t forget to make a stop at the captivating Villa D'este.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a lovely meal at Caffè Antica Roma, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Maccheroni is another top choice with a popular menu. You could also check for a table at In Roma - since 1917. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

Raise your glass to another unforgettable day in Italy!

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Day12

Day 12

  • Rome - Departure day
  • More
  • Altare della Patria
  • More

Day 12 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Altare Della Patria, a noteworthy monument before you head out.

For a shopping spree in Rome, we recommend the lively Galleria San Pietro. Here, you'll find a range of shops you can browse for some souvenir shopping.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
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From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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