13-Day Italy Road Trip from Bologna to Milan, Genoa, Florence, Perugia, Rome, and Siena

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Bologna. At the end of the day, you will enjoy the comforts of a top-rated hotel in Milan, which will be your home away from home for 2 nights.

Your sightseeing of the day begins at Two Towers, a remarkable tower where it’s easy to get lost in exploration. This top attraction is rated an average of 4.7 out of 5 stars in 25,975 reviews.

Next, satisfy your wanderlust at Piazza Santo Stefano. This square has an average rating of 4.8 out of 5 stars from 7,617 travelers.

International Museum And Library Of Music is another must-visit attraction. This renowned music museum offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.5 out of 5 stars by 742 travelers and attracting 13,413 annual visitors, it's one of the more popular places to see in the area.

At the end of the day, you will drive to Milan, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Milan's most popular restaurants, and connect with friendly locals for an authentic adventure.

Set out on a gastronomic journey in Milan by reserving a table at Enrico Bartolini al Mudec. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of creative cuisine. For a different taste, head over to Seta by Antonio Guida, renowned for its delectable international, and contemporary dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Il Luogo Aimo e Nadia, a highly rated local gem known for its exquisite italian contemporary, and modern menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Milan.

After enjoying a fulfilling meal, continue your evening at Nottingham Forest, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Armani/bamboo Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Mag Cafe provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Day 3 offers a multitude of experiences. You will stay in Milan for 1 night more, offering you enough time to explore at a relaxed pace.

Make Duomo Di Milano Museum one of your first sightseeing stops in Milan. Rated an average of 4.8 out of 5 stars by 138,554 travelers, a visit to this local attraction makes for a great introduction to the area. This art museum attracts 341,609 visitors every year.

Galleria Vittorio Emanuele Ii is a worthwhile attraction you can visit next. This commercial gallery is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 91,394 reviews.

Today is also the perfect opportunity to drop by La Scala. This opera house has been rated an average of 4.7 out of 5 stars by 26,219 visitors.

If you’re keen to explore more, head to Pinacoteca Di Brera and find out why 417 people visit this spot every year. A trip to this popular art museum is also your opportunity to see if it lives up to the reputable 4.7 out of 5-star rating as given by 26,077 previous visitors.

Another top place to visit is Piazza Gae Aulenti. This square enjoys an average rating of 4.6 out of 5 stars from 30,398 local and international travelers.

You can learn more about Milan today by going on a tour. Milan offers many top-rated tours and unique experiences that will inspire you. You can browse and select your favorites below.

As dinnertime approaches, it's time to head out for a bite to eat in Milan. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Nero 9, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Ristorante la Brisa, another top spot with a mouthwatering menu. You might also want to secure a reservation at UNAHOTELS Cusani Milano. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Milan this evening.

Extend your evening after a delightful meal by visiting Kilburn Cocktail Bar Milano, which offers the perfect atmosphere for a night out. Moreover, Bar Frida is another popular option for a drink or two. Likewise, The Friends Pub Milano also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Savor another day of unforgettable experiences in Italy!

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Milan, and Monza. When you’re not sightseeing, take time to relax at your selected hotel in Genoa, where you’ll be staying for 1 night.

Be one of the day’s first visitors at Museo Della Scienza E Della Tecnologia "leonardo Da Vinci". This technology museum is rated an average of 4.5 out of 5 stars by 22,235 visitors. Attracting more than 532,084 yearly visitors, it’s a top sight you don’t want to miss.

When you’re finished at Museo Della Scienza E Della Tecnologia "leonardo Da Vinci", head to Sforzesco Castle Art Library. This one-of-a-kind library is rated an average of 4.6 out of 5 stars in 68,714 reviews.

Beyond the above-mentioned attractions, you also have the opportunity to visit Parco Sempione. This park is rated an average of 4.6 out of 5 stars by 72,914 visitors.

If you’re keen to explore more, then consider a visit to Arch Of Peace. This monument is a much-appreciated attraction with an average rating of 4.6 out of 5 stars from 27,502 visitors.

Continue your road trip and head to your next destination, Monza. This car ride takes around 31 min.

A top pick for your self-guided sightseeing tour today is Monza Park. Previous visitors have rated this park an average of 4.7 out of 5 stars in 34,629 reviews.

When you’re done exploring for the day, you’ll drive to Genoa, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Genoa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Discover the culinary delights of Genoa by securing a reservation at San Giorgio. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of modern, and ligurian cuisine. For an alternative dining experience, try The Cook, renowned for its delicious modern dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Il Marin, a highly recommended local eatery celebrated for its mouthwatering seafood, and contemporary menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Keep the excitement of the evening going by visiting a bar or two. Scurreria Beer & Bagel is an excellent place to start. You could also check out La Lepre, offering a different kind of charm.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

On day 5 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Genoa, and Pisa. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Take the opportunity to see Piazza De Ferrari. This attraction has an average rating of 4.6 out of 5 stars from 34,312 visitors.

Aquarium Of Genoa is another sightseeing hotspot in the area. This public aquarium has been rated an average of 4.5 out of 5 stars by 62,259 travelers. Up to 1,200,000 people visit Aquarium Of Genoa every year.

Pisa’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Genoa behind. This drive usually takes around 2 hours 5 min. Pisa welcomes you with a multitude of unique vacation experiences.

Take the opportunity to see Leaning Tower Of Pisa. This attraction has an average rating of 4.7 out of 5 stars from 116,882 visitors and gets around 3,200,000 visits every year.

Piazza Del Duomo, Pisa is another sightseeing hotspot in the area. This square has been rated an average of 4.7 out of 5 stars by 104,550 travelers.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a harmony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Known for its 3-star Michelin status, Enoteca Pinchiorri offers a delightful variety of dishes highlighting its delicious italian contemporary menu. If you're seeking an alternative culinary experience, be sure to explore Santa Elisabetta, a highly recommended restaurant known for its enticing creative, and mediterranean cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Gucci Osteria da Massimo Bottura, a highly acclaimed restaurant celebrated for its exceptional italian contemporary, and international menu.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Archea Brewery provides a great setting to enjoy the night away.

Relax and recharge in preparation for another adventurous day in Italy!

Day 6 of your road trip across Italy promises a magnificent time exploring Florence. You have 1 night left in Florence. Take the opportunity to experience more of the best attractions and activities in the city.

Seize the day by visiting some of the best attractions in the area, like Piazzale Michelangelo. This extraordinary square has an average rating of 4.8 out of 5 stars from 77,744 visitors.

Next, make your way to Basilica Of Santa Croce In Florence. This church is rated an average of 4.7 out of 5 stars in 28,544 reviews.

While in Florence, we also recommend a visit to Piazza Della Signoria. This square has been rated an average of 4.8 out of 5 stars in 66,956 reviews.

If you’re keen to explore even more, then consider a visit to Uffizi Gallery. This attraction gets around 2,011,219 yearly visitors. With an average rating of 4.7 out of 5 stars by 61,794 travelers, this national museum is a highly recommended stop on your sightseeing around Florence.

Make your way to Ponte Vecchio, perhaps the most famous deck arch bridge in Florence. This attraction is rated an average of 4.7 out of 5 stars in 118,099 reviews.

To immerse yourself in more memorable moments in Florence, check out the best-rated tours the region offers. You can discover and choose from all of the top-rated activities you can do on this day in Florence below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at Trattoria Da Burde, a top pick for dinner tonight. Alternatively, Ristorante Buca Mario beckons with its unique menu offerings. Also, consider Eataly Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Florence. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Perugia. You will spend 1 night here for some well-deserved relaxation.

Begin your sightseeing with a visit to Cathedral Of Santa Maria Del Fiore. This church is rated an average of 4.8 out of 5 stars in 76,359 reviews.

Next up, make your way to Basilica Di Santa Maria Novella, Firenze (fi). This archives has an average rating of 4.7 out of 5 stars from 23,075 reviews.

When you’re ready for your next sight of the day, continue to Central Market. This sightseeing destination has an average rating of 4.4 out of 5 stars from 43,100 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit Galleria Dell'accademia. This national museum is rated an average of 4.6 out of 5 stars by 34,429 visitors. Visiting Galleria Dell'accademia means you'll be one of 1,719,645 people who do so every year.

At the end of the day, you will drive to Perugia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Perugia. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delightful dinner at Ristorante Settimo Sigillo, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bar Pellas? It's another excellent option with a diverse menu. Consider reserving a table at La Taverna as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Perugia.

To truly maximize your evening out, consider visiting Tommi Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Valentina, another bar with an inviting ambiance. Similarly, Caffe Dal Perugino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Take some time to reflect on your day and savor another beautiful night in Italy.

Dive into day 8 of your remarkable road trip in Italy. Today you will explore Vatican City, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Rome. You’ll stay here for 3 nights.

Once you're ready to continue your road trip, it's time to buckle up and drive towards Vatican City, eagerly anticipating your arrival in Vatican City. This drive usually takes around 2 hours 17 min, without any stops or traffic disruptions.

A top pick for your self-guided sightseeing tour today is Vatican Museums. Over 1,612,530 travelers visit this attraction every year. Previous visitors have rated this art museum an average of 4.6 out of 5 stars in 133,310 reviews.

Saint Peter's Square is a local recommendation that you also can pay a visit today. This square is rated an average of 4.8 out of 5 stars in 38,954 reviews.

Another attraction you won't want to miss is Sistine Chapel. This chapel is rated an average of 4.7 out of 5 stars in 52,083 reviews.

St. Peter's Basilica is another outstanding experience in Vatican City. Around 131,043 travelers have rated this major basilica an average of 4.8 out of 5 stars. The attraction hosts 11,000,000 visitors annually.

When you’re done exploring for the day, you’ll drive to Rome, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy an outstanding dining experience at La Pergola, a 3-star Michelin restaurant offering an exceptional mediterranean, and contemporary menu. If you are in the mood for trying an alternative dining experience, consider visiting the nearby 2-star Michelin-awardee, Il Pagliaccio, known for its delicious creative, and innovative cuisine. Another highly-recommended restaurant in Rome is Enoteca La Torre, a renowned restaurant with a 2-star Guide Michelin recognition, known for its delicious mediterranean, and creative menu.

Unwind after your meal by stepping into La Botticella Of Poggi Giovanni. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Sant' Eustachio Caffè offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Say good night to Rome and look forward to another great day of your road trip in Italy!

Day 9 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.

Make Circus Maximus your first stop of the day. Previous visitors have rated this circus an average of 4.4 out of 5 stars in 44,741 reviews.

Next up, make a stop at Colosseum. With an average rating of 4.7 out of 5 stars by 328,821 visitors, it's easy to understand why so many people visit this roman amphitheatre every year. In fact, this attraction welcomes 7,400,000 annual visitors.

Roman Forum is another attraction you can visit on this day of your vacation. This square has an average rating of 4.7 out of 5 stars by 114,450 visitors.

When you’re finished at Roman Forum, the perfect next stop is Altare Della Patria. This architectural structure is rated an average of 4.8 out of 5 stars in 49,843 reviews. Altare Della Patria attracts approximately 1,683,070 visitors annually.

If you’re keen to explore even more, then consider a visit to Trevi Fountain. This sculpture is a top place to visit, with a rating of 4.8 out of 5 stars from 343,494 reviews.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at DEROMA - Farine Romane, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Rome this evening.

After your meal, keep the night alive at a bar like The Apartment Bar Roma, known for its lively atmosphere. Hotel Hassler Roma is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 10 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.

Take the opportunity to see Castel Sant'angelo. This attraction has an average rating of 4.7 out of 5 stars from 72,431 visitors and gets around 918,591 visits every year.

Spanish Steps is another sightseeing hotspot in the area. This monumental staircase has been rated an average of 4.5 out of 5 stars by 57,211 travelers.

Rome is also the home of Piazza Di Spagna. Around 113,658 people have rated this square an average of 4.7 out of 5 stars.

Another place you’ll want to visit is Pantheon, which hosts up to 30,000,000 visitors every year. With an average rating of 4.8 out of 5 stars from a total of 189,682 reviews, a visit to this roman temple is a great idea.

This day of your vacation in Rome is also your chance to admire Piazza Navona. This must-visit square enjoys an average rating of 4.7 out of 5 stars from 158,771 reviews.

Don’t forget to check out all the popular tours and activities you can add to your travel plan. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at Ristorante Tema, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Maccheroni, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of RoYaL Art Cafè Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Raise your glass to another unforgettable day in Italy!

Embark on another extraordinary experience on day 11 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, which will be your home away from home for 1 night.

Begin your sightseeing with a visit to Largo Di Torre Argentina. This extraordinary square is rated an average of 4.5 out of 5 stars by 30,433 visitors.

Next, make your way to Campo De' Fiori. This top attraction is a square with an average rating of 4.4 out of 5 stars by 51,133 visitors.

We also recommend a visit to Basilica Di Santa Maria Maggiore. This major basilica is rated 4.8 out of 5 stars by 27,678 travelers.

If you’re keen to keep exploring, visit Piazza Del Popolo. This highly recommended sightseeing destination has received an average rating of 4.6 out of 5 stars from 89,807 travelers.

Today is also your chance to spend some time at Villa Borghese. This urban zone of rome is rated an average of 4.6 out of 5 stars by 69,749 travelers.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Antica Trattoria Papei, a top recommendation for dinner tonight. Or, for a change of pace, Osteria Quattro Venti boasts a menu that's sure to impress. Also, be sure to check out Osteria da Divo. Known as a local hotspot, it’s a great choice for tonight in Siena.

Cap off your dinner by heading to Meet Life Cafè, ideal for a leisurely evening with a drink in hand. Maudit Pub is another bar that offers an enjoyable setting. Similarly, Bar Impero Siena is also a popular place to go on a night out, perfect for relaxing and socializing.

Savor another day of unforgettable experiences in Italy!

On day 12 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena, and Lucca. When you’re not sightseeing, take time to relax at your selected hotel in Bologna, where you’ll be staying for 1 night.

Kick off the day at Piazza Del Campo, a top pick for today’s sightseeing. This square is rated an average of 4.8 out of 5 stars in 64,175 reviews.

Today is also your chance to visit Siena Cathedral. Siena Cathedral is a domus with an average rating of 4.8 out of 5 stars from 21,656 reviews.

Basilica Of San Domenico is another top attraction we highly recommend you visit today. This minor basilica is rated an average of 4.6 out of 5 stars by 3,290 visitors.

Embrace the thrill of the open road as you wave goodbye to Siena and set your GPS to Lucca. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 45 min. Upon reaching Lucca, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Drop by the renowned Piazza Dell'anfiteatro. This popular square has been rated an average of 4.6 out of 5 stars by 24,190 visitors.

At the end of the day, you will drive to Bologna, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Bologna's most popular restaurants, and connect with friendly locals for an authentic adventure.

Get ready for an unforgettable culinary journey in Bologna by reserving a table at Ahimè. Renowned as a Bib Gourmand restaurant, it offers an exceptional country cooking menu. For a different taste experience, head to I Portici, recognized for its delicious creative, and contemporary dishes. This 1-star Michelin restaurant consistently impresses guests, ensuring a memorable addition to your holiday. Looking for another option? Make sure to visit Trattoria di Via Serra, a local favorite known for its delightful emilian cuisine in Bologna. Nestled in the heart of the city, this Bib Gourmand awardee is an ideal choice for discerning emilian foodies seeking culinary excellence.

Keep the evening going at Bar Senza Nome, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bar Maurizio, which offers a similarly pleasant setting and great drinks. Another option is Brewdog Bar Bologna, which provides an inviting environment for unwinding after a busy day out.

Celebrate another amazing day of your road trip adventure in Italy!