13-Day Italy Self-Drive Road Trip With Itinerary from Perugia traveling west to Rome, Siena, Venice, Verona, Milan, Genoa, and Florence

Embark on another extraordinary experience on day 2 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Perugia. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.

Brace yourself for today’s incredible lineup of attractions in Perugia, featuring family-friendly attractions, scenic views, and picturesque spots. Start at The Fontana Maggiore, a worthwhile monument in the city. Then, head to Piazza Iv Novembre and soak in the ambiance of this symbolic public square.

There are many interesting places to see in Perugia, and when you are ready for more, go to Rocca Paolina. This is one of the city’s most frequently visited heritage-rich spots of interest.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Discover the culinary delights of Rome by securing a reservation at La Pergola. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of mediterranean and contemporary cuisine. For an alternative dining experience, try Il Pagliaccio, renowned for its delicious creative and innovative dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Enoteca La Torre, a highly recommended local eatery celebrated for its mouthwatering mediterranean and creative menu. With its 2-star Michelin recognition, it offers an unforgettable dining adventure.

Continue your evening by exploring the vibrant nightlife scene at La Botticella Of Poggi Giovanni, a prime destination for a thrilling night out. Also, don’t forget to check out Almalu Trastevere, a bar that offers unique local touches. Likewise, Bar Viminale Di Pepi Maurilio provides an excellent alternative for a fun evening.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Day 3 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Rome is brimming with adventures. Today’s wonderful stops include a castle, a public square, a monument, an archeological site and much more! Begin your sightseeing adventure at the spectacular Castel Sant'angelo and allow yourself time to explore. Just a short distance away you'll find your next stop, Piazza Navona, a romantic public square that draws visitors from far and near.

Continue your journey to Pantheon, one of the city’s most globally renowned spots that you shouldn’t miss. Another great site to visit is the timeless Roman Forum. When you're finished at the archeological site, Colosseum awaits your visit. This archeological site is a picture-perfect highlight on today's itinerary.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a lovely dining experience at RomAntica, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Coso Ristorante, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated DEROMA - Farine Romane. It’s yet another ideal choice to enhance your time in Rome tonight.

Continue your lively evening at Sant' Eustachio Caffè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Yellowsquare Rome is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffè Portofino ensures a night out tailored to your taste.

Savor another day of unforgettable experiences in Italy!

Day 4 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Savor the day by visiting some of the best places to see in Rome, including a monument, a public square, and a park. Start your adventure at Trevi Fountain. This world-famous monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Piazza Di Spagna located in Rome for another exciting encounter.

Next, immerse yourself in the setting of Spanish Steps. Its enchanting features will captivate you. After the public square, continue your tour of the city with a visit to Piazza Del Popolo. Visitors usually appreciate the history-steeped features of this public square. Next up is Villa Borghese, a highly recommended park.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at The Apartment Bar Roma, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Hotel Hassler Roma offers a vibrant space for indulging in well-crafted drinks and engaging conversation.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 1 night here for some well-deserved relaxation.

Start at St. Peter's Basilica, a world-famous major basilica that is worthwhile a visit in the city. Continue your exploration at Saint Peter's Square. This square is one of the city’s most well-known spots.

Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Vatican Museums.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Enoteca I Terzi, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Tar-Tufo boasts a menu that's sure to impress. Also, be sure to check out Antica Trattoria Papei. Known as a local hotspot, it’s a great choice for tonight in Siena.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Meet Life Cafè, a well-loved spot among locals and tourists. Or, head to Maudit Pub. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Impero Siena, another top-rated place in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena and Bologna. When you’re not sightseeing, take time to relax at your selected hotel in Venice, where you’ll be staying for 1 night.

Savor the day by visiting some of the best places to see in Siena, including a public square, a church, and a mosque. Start your adventure at Piazza Del Campo. This astonishing public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Siena Cathedral located in Siena for another exciting encounter.

Next, immerse yourself in the setting of Faizan-e-madina Bologna. Its inviting features will captivate you.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Enjoy an outstanding dining experience at Local, a 1-star Michelin restaurant offering an exceptional contemporary menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Wistèria, known for its delicious contemporary and venetian cuisine. Another highly-recommended place to eat in Venice is Quadri, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious modern menu.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Al Parlamento stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Caffe Rosso offers an ideal atmosphere to enjoy the pleasures of the night. Adagio is also a great option that provides a perfect setting for a relaxing evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 7 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Venice. In the evening, you’ll end up in Verona, where you will stay for 1 night.

Discover a day packed with family-friendly attractions, romantic experiences, and scenic views in Venice. Begin your sightseeing with Rialto Bridge. This timeless historical landmark is one of the top attractions in the city. Proceed to Piazza San Marco, another must-visit attraction.

As you wander through the inviting streets of Venice, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to St Mark's Basilica. This locally renowned church is a traveler-favorite. Not far away, you’ll find Doge's Palace, another key site on your sightseeing itinerary. Bridge Of Sighs is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

At the end of the day, you will drive to Verona, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Verona. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a memorable dining experience in Verona by booking a table at Osteria Mondo d'Oro, renowned as a Bib Gourmand restaurant presenting an exceptional italian and seasonal menu. For a different culinary experience in Verona, Casa Perbellini 12 Apostoli shines as one of the top destinations, known for its delicious creative and contemporary cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Il Desco is known as a top local spot for its delicious italian contemporary cuisine in Verona. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Continue your lively evening at Archivio, a perfect place for winding down or revving up the night, depending on which mood you’re in. La Segreteria Café is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Grande Giove Cocktail Bar ensures a night out tailored to your taste.

Take some time to reflect on your day and savor another beautiful night in Italy.

Embark on another extraordinary experience on day 9 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Milan. At the end of the day, you will enjoy the comforts of a top-rated hotel in Genoa, which will be your home away from home for 1 night.

Today, you'll explore some of the most beautiful places in Milan, including a church, a shopping mall, an opera house, a castle, a park and much more! Start your day with a visit to Duomo Di Milano Museum. This timeless church is a must-visit in the city. When you’re ready for your next discovery, continue to Galleria Vittorio Emanuele Ii, which may be one of the most history-steeped places you will experience today.

One of the best things about exploring Milan on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to La Scala, a well-known opera house in the city. If you’re up for more discoveries, don’t forget to reserve some time for Sforzesco Castle Art Library and Parco Sempione.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Experience a harmony of flavors at San Giorgio in Genoa by securing a reservation in advance. Known for its 1-star Michelin status, San Giorgio offers a delightful variety of dishes highlighting its delicious modern and ligurian menu. If you're seeking an alternative culinary experience, be sure to explore The Cook, a highly recommended restaurant known for its enticing modern cuisine. This popular 1-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Il Marin, a highly acclaimed restaurant celebrated for its exceptional seafood and contemporary menu.

Keep the excitement of the evening going by visiting a bar or two. Scurreria Beer & Bagel is an excellent place to start. You could also check out La Lepre, offering a different kind of charm. A last recommendation for the day is Bar Pisacane Iii. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Head back to your accommodation in Genoa and get some rest in preparation for another magical day of your road trip in Italy!

Experience an unparalleled adventure on day 10 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Genoa and Pisa. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 2 nights here for some well-deserved relaxation.

Start by visiting Piazza De Ferrari, a prime spot to begin your journey. This respected public square is sure to impress. Next on your list is Aquarium Of Genoa, another must-visit landmark and extraordinary aquarium renowned for its mesmerizing features.

While exploring and sightseeing, take time to savor the culture of Genoa by sampling some local delicacies. When you’re ready for more sightseeing, head to Leaning Tower Of Pisa. This breathtaking monument is an essential place to visit for anyone looking for the full Genoa experience. We also recommend visiting Piazza Del Duomo, Pisa, a timeless public square.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a taste of local culinary excellence while in Florence by securing a table at Enoteca Pinchiorri. An esteemed 3-star Michelin restaurant, it features an exceptional italian contemporary menu. For an alternative taste experience, visit Santa Elisabetta, famous for its scrumptious creative and mediterranean dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Palagio, a local favorite celebrated for its exquisite italian contemporary cuisine in Florence. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for italian contemporary cuisine lovers seeking top-notch culinary experiences.

Unwind after your meal by stepping into Manifattura. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Se·sto On Arno Rooftop Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Il Vinile, another top-rated bar in the area.

Celebrate another amazing day of your road trip adventure in Italy!

On day 11 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Florence allows for both. Start by heading to The Boboli Gardens. This notable botanical garden provides an insightful glimpse into the city's identity. Next, discover Cathedral Of Santa Maria Del Fiore, an inviting church, promising a delightful encounter.

Continue your sightseeing with a visit to Central Market, a notable food market. When you’re done, don’t forget to make a stop at the well-known Galleria Dell'accademia.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Ditta Artigianale, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Da Burde boasts a menu that's sure to impress. Also, be sure to check out Casa Toscana. Known as a local hotspot, it’s a great choice for tonight in Florence.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 12 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.

Today’s agenda in Florence includes a public square, a historical landmark, an art gallery, a church, an observation deck and much more! Piazza Della Signoria is must-visit public square and a great starting point for the day. Next, continue your journey to Ponte Vecchio, a world-famous historical landmark, located just a leisurely stroll away. Next, head to Uffizi Gallery, a history-steeped art gallery, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Florence. When you're ready, let your sightseeing route take you to the interesting Basilica Of Santa Croce In Florence. If you’re looking for more, Piazzale Michelangelo is also an astonishing attraction that is worthwhile a visit.

When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Perugia's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at La Taverna, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Ristorante del Sole, another top spot with a mouthwatering menu. You might also want to secure a reservation at Al Mangiar Bene. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Perugia this evening.

After savoring a delicious meal, step into the vibrant nightlife at Caffè Fortebraccio, where the evening is just getting started. In the same way, Caffe Del Banco offers a unique charm perfect for experiencing the local bar scene in Perugia. Dempsey's Perugia is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass to another unforgettable day in Italy!