13-Day Italy Road Trip from Pisa to Bologna, Venice, Florence, Arezzo, Rome, and Siena

On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Pisa, Cascine Vecchie, and San Piero a Grado. In the evening, you’ll end up in Bologna, where you will stay for 1 night.

Kick off the day at Leaning Tower Of Pisa, a top pick for today’s sightseeing. Attracting approximately 3,200,000 visits every year, this attraction is a must-see. This bell tower is rated an average of 4.7 out of 5 stars in 116,882 reviews.

Today is also your chance to visit Piazza Del Duomo, Pisa. Piazza Del Duomo, Pisa is a square with an average rating of 4.7 out of 5 stars from 104,550 reviews.

Pisa Cathedral is another top attraction we highly recommend you visit today. This cathedral is rated an average of 4.8 out of 5 stars by 8,361 visitors.

Set your GPS to Cascine Vecchie and hit the road. Expect a journey of approximately 9 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Cascine Vecchie beckons with new experiences!

Kick off the day at Parco Regionale Migliarino, San Rossore, Massaciuccoli, a top pick for today’s sightseeing. This park is rated an average of 4.4 out of 5 stars in 9,632 reviews.

When you’re done exploring for the day, you’ll drive to Bologna, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Bologna, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Prepare for an extraordinary culinary adventure in Bologna by booking a table at Ahimè, a Bib Gourmand restaurant that boasts an exceptional country cooking menu. For a different flavor experience, head to I Portici, renowned for its delectable creative, and contemporary dishes. This 1-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Trattoria di Via Serra, a local gem known for its delightful emilian cuisine in Bologna. Nestled in the city's heart, this Bib Gourmand-awardee is a perfect choice for discerning restaurant-goers seeking a new experience.

If you’re not ready to end the night just yet, Bar Freud E Squisito offers a perfect venue to relax and savor a drink. Similarly, Osteria Del Sole is well-suited for those looking to unwind in a social setting. Macondo - Cocktail Bar is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Bologna, and Padua. When you’re not sightseeing, take time to relax at your selected hotel in Venice, where you’ll be staying for 3 nights.

Take the opportunity to see Piazza Maggiore. This attraction has an average rating of 4.7 out of 5 stars from 64,523 visitors.

Two Towers is another sightseeing hotspot in the area. This tower has been rated an average of 4.7 out of 5 stars by 25,975 travelers.

Bologna is also the home of Piazza Santo Stefano. Around 7,617 people have rated this square an average of 4.8 out of 5 stars.

As you’ve unraveled the marvels of Bologna, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Padua may take around 1 hour 28 min. Upon your arrival in Padua, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Start your sightseeing with a visit to The Basilica Of St. Anthony. This church is rated an average of 4.8 out of 5 stars from 38,852 visitors.

Prato Della Valle is another popular attraction you could visit today. This square has a rating of 4.6 out of 5 stars from 47,576 visitors.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Have a memorable dining experience in Venice by booking a table at Local, renowned as a 1-star Michelin restaurant presenting an exceptional contemporary menu. For a different culinary experience in Venice, Wistèria shines as one of the top destinations, known for its delicious contemporary, and venetian cuisine. This 1-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Quadri is known as a top local spot for its delicious modern cuisine in Venice. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

To truly maximize your evening out, consider visiting Al Parlamento after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Adagio, another bar with an inviting ambiance. Similarly, Il Mercante also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Head back to your accommodation in Venice and get some rest in preparation for another magical day of your road trip in Italy!

Day 4 offers a multitude of experiences. You will stay in Venice for 2 nights more, offering you enough time to explore at a relaxed pace.

Begin your sightseeing with a visit to Rialto Bridge. This stone bridge is rated an average of 4.7 out of 5 stars in 141,666 reviews.

Next up, make your way to Piazza San Marco. This square has an average rating of 4.7 out of 5 stars from 152,982 reviews.

When you’re ready for your next sight of the day, continue to St Mark's Basilica. This cathedral has an average rating of 4.7 out of 5 stars from 18,439 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit Doge's Palace. This palace is rated an average of 4.7 out of 5 stars by 24,775 visitors. Visiting Doge's Palace means you'll be one of 318,104 people who do so every year.

If you’re keen to explore even more, then consider a visit to Bridge Of Sighs. This footbridge is a much-appreciated attraction with an average rating of 4.6 out of 5 stars from 18,223 visitors.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Cantina Do Spade, a top-rated dining spot in Venice. If you're in the mood for something new, try Trattoria Al Gazzettino, another premier location with a delectable menu. You might also want to book a table at Trattoria Bar Pontini. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Venice.

After enjoying a fulfilling meal, continue your evening at The Irish Pub Venezia, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Dolce Vita Venezia offers a welcoming atmosphere for easing into the nightlife. Similarly, Devils Forest Pub provides an excellent environment for a relaxed and enjoyable evening.

Head back to your accommodation in Venice and get some rest in preparation for another magical day of your road trip in Italy!

On day 5 of your road trip in Italy, you’ll start and end your day in Lido, but spend the day exploring what’s beyond the town. Since you will return to Venice for 1 night more, there’s no need to rush. Experience Lido, Venice, and Campalto to the fullest today with this curated day itinerary!

Begin your sightseeing with a visit to Venetian Arsenal. This naval arsenal is rated an average of 4.6 out of 5 stars in 8,749 reviews.

Next up, make your way to Gallerie Dell'accademia. This art museum has an average rating of 4.5 out of 5 stars from 7,950 reviews. Usually, around 210,149 people visit Gallerie Dell'accademia every year.

When you’re ready for your next sight of the day, continue to Santa Maria Gloriosa Dei Frari. This parish church has an average rating of 4.7 out of 5 stars from 9,174 visitors.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Lido.

Take the opportunity to see Giardini Della Biennale. This attraction has an average rating of 4.5 out of 5 stars from 10,729 visitors.

After soaking in Venice’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Campalto. Expect your car journey to take a minimum of 10 min. When you arrive in Campalto, it's time to take a break from the road.

Journey into the unknown at Parco San Giuliano, a unique attraction awaiting your visit. This remarkable park has an average rating of 4.4 out of 5 stars from 7,776 reviews.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Venice.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delicious dinner at La Palanca, an excellent option for tonight's dining. Looking for something different? Farini offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Dona Onesta. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Venice.

Extend your evening after a delightful meal by visiting Bar Al Vecio Calice, which offers the perfect atmosphere for a night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Venice. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 1 night.

Begin your sightseeing with a visit to Palazzo Contarini Del Bovolo. This sightseeing destination is rated an average of 4.5 out of 5 stars in 11,745 reviews.

Next up, make your way to Teatro La Fenice. This opera house has an average rating of 4.7 out of 5 stars from 10,677 reviews.

When you’re ready for your next sight of the day, continue to Peggy Guggenheim Collection. This art museum has an average rating of 4.6 out of 5 stars from 10,128 visitors. Up to 92,922 people visit this place of interest annually.

Beyond the above-mentioned attractions, you also have the opportunity to visit Santa Maria Della Salute. This votive church is rated an average of 4.7 out of 5 stars by 8,681 visitors.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Experience a taste of local culinary excellence while in Florence by securing a table at Enoteca Pinchiorri. An esteemed 3-star Michelin restaurant, it features an exceptional italian contemporary menu. For an alternative taste experience, visit Santa Elisabetta, famous for its scrumptious creative, and mediterranean dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Palagio, a local favorite celebrated for its exquisite italian contemporary cuisine in Florence. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for italian contemporary cuisine lovers seeking top-notch culinary experiences.

Extend your evening after a delightful meal by visiting Manifattura, which offers the perfect atmosphere for a night out. Moreover, Se·sto On Arno Rooftop Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Celebrate another amazing day of your road trip adventure in Italy!

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Florence, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Arezzo. You’ll stay here for 1 night.

Make Piazza Della Signoria your first stop of the day. Previous visitors have rated this square an average of 4.8 out of 5 stars in 66,956 reviews.

Next up, make a stop at Cathedral Of Santa Maria Del Fiore. With an average rating of 4.8 out of 5 stars by 76,359 visitors, it's easy to understand why so many people visit this church every year.

Ponte Vecchio is another attraction you can visit on this day of your vacation. This deck arch bridge has an average rating of 4.7 out of 5 stars by 118,099 visitors.

When you’re finished at Ponte Vecchio, the perfect next stop is Uffizi Gallery. This national museum is rated an average of 4.7 out of 5 stars in 61,794 reviews. Uffizi Gallery attracts approximately 2,011,219 visitors annually.

If you’re keen to explore even more, then consider a visit to Piazzale Michelangelo. This square is a top place to visit, with a rating of 4.8 out of 5 stars from 77,744 reviews.

When you’re done exploring for the day, you’ll drive to Arezzo, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Arezzo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dive into a culinary adventure like no other in Arezzo by booking a table at Octavin. This popular restaurant holds 1 Michelin star and offers an exceptional menu of creative cuisine. If you're in the mood to try something new, consider La Clandestina, another top spot with a mouthwatering menu.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Liquid Bar, a well-loved spot among locals and tourists.

Say good night to Arezzo and look forward to another great day of your road trip in Italy!

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 3 nights here for some well-deserved relaxation.

After soaking in Arezzo’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Vatican City, Vatican City. Expect your car journey to take a minimum of 2 hours 32 min. When you arrive in Vatican City, it's time to take a break from the road.

Begin your sightseeing with a visit to Vatican Museums. This art museum gets 1,612,530 visitors each year and is rated an average of 4.6 out of 5 stars in 133,310 reviews.

Next up, make your way to Saint Peter's Square. This square has an average rating of 4.8 out of 5 stars from 38,954 reviews.

When you’re ready for your next sight of the day, continue to Sistine Chapel. This chapel has an average rating of 4.7 out of 5 stars from 52,083 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit St. Peter's Basilica. This major basilica is rated an average of 4.8 out of 5 stars by 131,043 visitors. Visiting St. Peter's Basilica means you'll be one of 11,000,000 people who do so every year.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Rome. Rome offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Set out on a gastronomic journey in Rome by reserving a table at La Pergola. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of mediterranean, and contemporary cuisine. For a different taste, head over to Il Pagliaccio, renowned for its delectable creative, and innovative dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Enoteca La Torre, a highly rated local gem known for its exquisite mediterranean, and creative menu. With a 2-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Rome.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Sant' Eustachio Caffè, the perfect place for those looking to experience the best of the nightlife. Similarly, Caffè Portofino provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 9 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 2 nights and discover all the best things to see and do in the area.

Make Castel Sant'angelo one of your first sightseeing stops in Rome. Rated an average of 4.7 out of 5 stars by 72,431 travelers, a visit to this local attraction makes for a great introduction to the area. This museum attracts 918,591 visitors every year.

Piazza Navona is a worthwhile attraction you can visit next. This square is a valued place of interest in the area, with an average rating of 4.7 out of 5 stars from 158,771 reviews.

Today is also the perfect opportunity to drop by Trevi Fountain. This sculpture has been rated an average of 4.8 out of 5 stars by 343,494 visitors.

If you’re keen to explore more, head to Roman Forum. A trip to this popular square is also your opportunity to see if it lives up to the reputable 4.7 out of 5-star rating as given by 114,450 previous visitors.

Another top place to visit is Colosseum. This roman amphitheatre enjoys an average rating of 4.7 out of 5 stars from 328,821 local and international travelers. Approximately 7,400,000 people visit this attraction every year.

Don’t forget to check out all the popular tours and activities you can add to your travel plan. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at DEROMA - Farine Romane, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Centro. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Rome this evening.

Extend your evening after a delightful meal by visiting The Apartment Bar Roma, which offers the perfect atmosphere for a night out. Moreover, Hotel Hassler Roma is another popular option for a drink or two.

Celebrate another amazing day of your road trip adventure in Italy!

Day 10 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

Your sightseeing of the day begins at Piazza Del Popolo, a remarkable square where it’s easy to get lost in exploration. This top attraction is rated an average of 4.6 out of 5 stars in 89,807 reviews.

Next, satisfy your wanderlust at Piazza Di Spagna. This square has an average rating of 4.7 out of 5 stars from 113,658 travelers.

Spanish Steps is another must-visit attraction. This renowned monumental staircase offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.5 out of 5 stars by 57,211 travelers, it's one of the more popular places to see in the area.

Beyond the above-mentioned sites, you also have the opportunity to visit Pantheon. This well-loved roman temple boasts a 4.8 out of 5-star rating from 189,682 reviews. In a single year, approximately 30,000,000 visitors add this sightseeing spot to their travel itineraries.

When there’s still energy left for exploring, Basilica Di Santa Maria Maggiore awaits. If you’ve been interested in experiencing a major basilica, this is a top pick rated 4.8 out of 5 stars by 27,678 previous visitors.

Immerse yourself in the local scene through top-rated tours and activities. You can choose from a wide variety of easy to challenging tours and easily add them to your travel package below.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Ristorante Tema, a highly-rated dining destination in Rome. If you're eager to try something different, consider Maccheroni, another top spot with a tantalizing menu. You might also want to secure a reservation at RoYaL Art Cafè Roma. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Rome this evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 11 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Siena, where you will stay for 1 night.

Your sightseeing of the day begins at Altare Della Patria, a remarkable architectural structure where it’s easy to get lost in exploration. This top attraction is rated an average of 4.8 out of 5 stars in 49,843 reviews. Each year, this popular place of interest welcomes approximately 1,683,070 visitors.

Next, satisfy your wanderlust at Largo Di Torre Argentina. This square has an average rating of 4.5 out of 5 stars from 30,433 travelers.

Campo De' Fiori is another must-visit attraction. This renowned square offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.4 out of 5 stars by 51,133 travelers, it's one of the more popular places to see in the area.

Beyond the above-mentioned sites, you also have the opportunity to visit Circus Maximus. This well-loved circus boasts a 4.4 out of 5-star rating from 44,741 reviews.

When there’s still energy left for exploring, Villa Borghese awaits. If you’ve been interested in experiencing an urban zone of rome, this is a top pick rated 4.6 out of 5 stars by 69,749 previous visitors.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.

Dine in style at Antica Trattoria Papei, a top recommendation for dinner tonight. Or, for a change of pace, Osteria Quattro Venti boasts a menu that's sure to impress. Also, be sure to check out Osteria da Divo. Known as a local hotspot, it’s a great choice for tonight in Siena.

Let the evening flow smoothly from dinner to drinks at Meet Life Cafè, a top-rated bar in the area. For other recommendations, Maudit Pub provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Impero Siena offers a memorable night with diverse drink options and excellent service.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

On day 12 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Siena. When you’re not sightseeing, take time to relax at your selected hotel in Pisa, where you’ll be staying for 1 night.

Make Tower Of Mangia one of your first sightseeing stops in Siena. Rated an average of 4.6 out of 5 stars by 673 travelers, a visit to this local attraction makes for a great introduction to the area.

Piazza Del Campo is a worthwhile attraction you can visit next. This square is a valued place of interest in the area, with an average rating of 4.8 out of 5 stars from 64,175 reviews.

Today is also the perfect opportunity to drop by Siena Cathedral. This domus has been rated an average of 4.8 out of 5 stars by 21,656 visitors.

If you’re keen to explore more, head to Basilica Of San Domenico. A trip to this popular minor basilica is also your opportunity to see if it lives up to the reputable 4.6 out of 5-star rating as given by 3,290 previous visitors.

Another top place to visit is Fortezza Medicea (siena). This fortress enjoys an average rating of 4.5 out of 5 stars from 9,835 local and international travelers.

When you’re done exploring for the day, you’ll drive to Pisa, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Pisa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Ristorante alle Bandierine, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Barrique Cocktail And Bistrot? It's another excellent option with a diverse menu. Consider reserving a table at Filter Coffee Lab as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Pisa.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bar Mocambo stands out as an excellent choice for a post-dinner cocktail. Alternatively, Tree offers an ideal atmosphere to enjoy the pleasures of the night. Chupiteria is also a great option that provides a perfect setting for a relaxing evening.

Relax and recharge in preparation for another adventurous day in Italy!