13-Day Italy Road Trip from Pisa traveling south to Arezzo, Rome, Province of Salerno, Naples, L'aquila, Perugia, and Florence

On day 2 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Pisa, and Tirrenia. When you’re not sightseeing, take time to relax at your selected hotel in Arezzo, where you’ll be staying for 1 night.

When you're ready to see some sights, Leaning Tower Of Pisa is a great place to start. This bell tower is rated an average of 4.7 out of 5 stars by 116,882 visitors. Leaning Tower Of Pisa attracts more than 3,200,000 visitors every year.

Another popular attraction you can visit today is Piazza Del Duomo, Pisa. This square has an average rating of 4.7 out of 5 stars from 104,550 travelers.

We also recommend a stop at Pisa Cathedral. The cathedral has been rated an average of 4.8 out of 5 stars by 8,361 visitors.

Continue your road trip and head to your next destination, Tirrenia. This car ride takes around 22 min.

Seize the day by visiting some of the best attractions in the area, like Bagno Degli Americani. This extraordinary sightseeing destination has an average rating of 4.2 out of 5 stars from 2,992 visitors.

When you’re done exploring for the day, you’ll drive to Arezzo, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Arezzo, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Prepare for an extraordinary culinary adventure in Arezzo by booking a table at Octavin, a 1-star Michelin restaurant that boasts an exceptional creative menu. If you're eager to try something different, consider La Clandestina, another top spot with a tantalizing menu.

If you’re not ready to end the night just yet, Liquid Bar offers a perfect venue to relax and savor a drink.

Relax and recharge in preparation for another adventurous day in Italy!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Vatican City. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Rome. You will spend 3 nights here for some well-deserved relaxation.

Embrace the thrill of the open road as you wave goodbye to Arezzo and set your GPS to Vatican City, Vatican City. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 32 min. Upon reaching Vatican City, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

An excellent attraction to start your day with is Vatican Museums. This art museum typically receives around 1,612,530 visitors every year and is rated an average of 4.6 out of 5 stars in 133,310 reviews.

Continue your journey at Sistine Chapel. This chapel is rated 4.7 out of 5 stars by 52,083 travelers from near and far.

Vatican City is also the home of Saint Peter's Square. This square has an average rating of 4.8 out of 5 stars from 38,954 visitors.

You can continue your self-guided sightseeing tour at St. Peter's Basilica. A total of 11,000,000 people explore this attraction every year. Rated 4.8 out of 5 stars by 131,043 visitors, a visit to this top sight is time well spent.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for an authentic adventure.

Start your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean, and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative, and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean, and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Sant' Eustachio Caffè, another bar with an inviting ambiance. Similarly, Caffè Portofino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Head back to your accommodation in Rome and get some rest in preparation for another magical day of your road trip in Italy!

Day 4 of your road trip across Italy promises a magnificent time exploring Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Journey into the unknown at Campo De' Fiori, a unique attraction awaiting your visit. This remarkable square has an average rating of 4.4 out of 5 stars from 51,133 reviews.

When you’re ready to continue your sightseeing, Piazza Navona is a recommended place to visit. This square is rated an average of 4.7 out of 5 stars in 158,771 reviews.

Another must-see attraction in Rome is Pantheon. This spectacular roman temple gets over 30,000,000 visitors every year. Rated an average of 4.8 out of 5 stars by 189,682 travelers, this popular tourist destination in Rome offers an experience you will remember.

Roman Forum is another popular stop on travelers' itineraries in Rome. This square promises memorable moments of exploring. Other travelers have rated this attraction 4.7 out of 5 stars in 114,450 reviews.

Lastly, don't miss out on Colosseum. Rated 4.7 out of 5 stars by 328,821 local and international travelers, it's a popular place to visit. This roman amphitheatre gets closer to 7,400,000 visits every year.

Don’t forget to check out all the popular tours and activities you can add to your travel plan. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at DEROMA - Farine Romane, a top pick for dinner tonight. Alternatively, La Taverna Italiana beckons with its unique menu offerings. Also, consider Centro. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Explore the vibrant nightlife at The Apartment Bar Roma after your meal, a hub for lively evenings and memorable moments. Or, head to Hotel Hassler Roma for a great selection of flavorful drinks and a charming setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 5 of your road trip, you will have an entire day to explore Rome. You’ll stay in Rome for 1 night and discover all the best things to see and do in the area.

Take the opportunity to see Spanish Steps. This attraction has an average rating of 4.5 out of 5 stars from 57,211 visitors.

Piazza Di Spagna is another sightseeing hotspot in the area. This square has been rated an average of 4.7 out of 5 stars by 113,658 travelers.

Rome is also the home of Trevi Fountain. Around 343,494 people have rated this sculpture an average of 4.8 out of 5 stars.

Another place you’ll want to visit is Basilica Di Santa Maria Maggiore. With an average rating of 4.8 out of 5 stars from a total of 27,678 reviews, a visit to this major basilica is a great idea.

This day of your vacation in Rome is also your chance to admire Circus Maximus. This must-visit circus enjoys an average rating of 4.4 out of 5 stars from 44,741 reviews.

To do something one-of-a-kind on this day of your trip, you can join a tour. You can discover all of the most fun and eye-opening experiences in your destination below and secure your spot here.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Dine in style at Ristorante Tema, a top recommendation for dinner tonight. Or, for a change of pace, Maccheroni boasts a menu that's sure to impress. Also, be sure to check out RoYaL Art Cafè Roma. Known as a local hotspot, it’s a great choice for tonight in Rome.

Raise your glass to another unforgettable day in Italy!

Embark on another extraordinary experience on day 6 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Rome. At the end of the day, you will enjoy the comforts of a top-rated hotel in Province of Salerno, which will be your home away from home for 1 night.

An excellent attraction to start your day with is Altare Della Patria. This architectural structure typically receives around 1,683,070 visitors every year and is rated an average of 4.8 out of 5 stars in 49,843 reviews.

Continue your journey at Castel Sant'angelo. This museum is rated 4.7 out of 5 stars by 72,431 travelers from near and far. Approximately 918,591 people come to this place of interest every year to enjoy a unique experience in Rome.

Rome is also the home of Piazza Del Popolo. This square has an average rating of 4.6 out of 5 stars from 89,807 visitors.

You can continue your self-guided sightseeing tour at Passeggiata Del Pincio. Rated 4.7 out of 5 stars by 11,134 visitors, a visit to this top sight is time well spent.

Lastly, don't miss out on Villa Borghese. With an average rating of 4.6 out of 5 stars from 69,749 reviews, it’s hard to refuse the opportunity to see this urban zone of rome.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Province of Salerno. Province of Salerno offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Province of Salerno. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a harmony of flavors at Re Maurì in Province of Salerno by securing a reservation in advance. Known for its 1-star Michelin status, Re Maurì offers a delightful variety of dishes highlighting its delicious creative menu. If you're looking to mix things up, Embarcadero offers an enticing alternative with its varied menu.

Keep the excitement of the evening going by visiting a bar or two. Hilton Bar E Gastronomia is an excellent place to start. You could also check out The Black Monday Speakeasy Tbm, offering a different kind of charm. A last recommendation for the day is Dòmo I' Vinaino Wine Bar - Enogastronomia. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Dive into day 7 of your remarkable road trip in Italy. Today you will explore Amalfi, Ravello, and Pompei, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Naples. You’ll stay here for 2 nights.

When you’re ready to jump back into the car and say goodbye to Province of Salerno, you’ll hit the road in the direction of Amalfi. This drive usually takes around 57 min. When you arrive, enjoy some sightseeing.

Begin your sightseeing with a visit to Amalfi Coast. This coast is rated an average of 4.7 out of 5 stars in 70,989 reviews.

Embrace the thrill of the open road as you wave goodbye to Amalfi and set your GPS to Ravello. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 19 min. Upon reaching Ravello, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Start your sightseeing with a visit to Villa Rufolo. This sightseeing destination is a popular stop on travelers’ itineraries in Ravello, with an average rating of 4.6 out of 5 stars by 16,456 visitors.

When you’re done exploring for the day, you’ll drive to Naples, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to an extraordinary dining experience at Veritas, a 1-star Michelin restaurant offering an incredible campanian, and contemporary menu. Alternatively, if your taste buds call for something different, Il Comandante is one of the best restaurants for creative, and mediterranean cuisine in Naples. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at ARIA. As a top-rated establishment with 1 Michelin star, it is an ideal choice for contemporary, and modern cuisine in the city.

Keep the evening going at Happening Cocktail Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Shanti Art Musik Bar, which offers a similarly pleasant setting and great drinks. Another option is Gran Caffè Gambrinus, which provides an inviting environment for unwinding after a busy day out.

Say good night to Naples and look forward to another great day of your road trip in Italy!

Day 8 of your road trip will take you to the best attractions Naples has to offer. Cherish the 1 night you have left in Naples by discovering the best things there are to see and do in the city.

When you’re ready for some sightseeing, make your way to Castel Nuovo. This much-appreciated castle is rated 4.4 out of 5 stars in 28,032 reviews.

Next up is Chiesa Del Gesù Nuovo. This church has an average rating of 4.6 out of 5 stars from 16,437 visitors.

Another top sightseeing recommendation is Cappella Sansevero. This former church has been rated 4.7 out of 5 stars in 25,405 reviews. Every year, 175,138 travelers include this attraction on their travel itinerary.

Naples National Archaeological Museum is another attraction you have the opportunity to visit today. This archaeological museum has an average rating of 4.6 out of 5 stars from 27,352 reviews. This popular attraction gets 616,878 visits every year.

There are plenty of experiences you can choose from in Italy that will add excitement to your vacation. When you’re keen to discover what else Naples has in store for you, use this day to go on a tour. Scroll down and select tours and activities to include on your itinerary for the day.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at La Lazzara Trattoria e Pizzeria, a top-rated dining destination in Naples. If you're in the mood to try something new, consider Trattoria Castel Nuovo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Amici Miei. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Naples this evening.

Keep the evening going at Archivio Storico - Cocktail Bar & Wonderfood, a great choice for enjoying the after-dinner hours with a drink. You could also go to Babette Pub, which offers a similarly pleasant setting and great drinks. Another option is Gran Caffè Cimmino, which provides an inviting environment for unwinding after a busy day out.

Say good night to Naples and look forward to another great day of your road trip in Italy!

On day 9 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Naples, and Caserta. In the evening, you’ll end up in L'aquila, where you will stay for 1 night.

Seize the day by visiting some of the best attractions in the area, like San Carlo Theatre. This extraordinary point of interest has an average rating of 4.8 out of 5 stars from 7,015 visitors.

Next, make your way to Piazza Del Plebiscito. This square is rated an average of 4.7 out of 5 stars in 58,141 reviews.

While in Naples, we also recommend a visit to Ovo Castle. This point of interest has been rated an average of 4.6 out of 5 stars in 33,595 reviews.

Set your GPS to Caserta and hit the road. Expect a journey of approximately 44 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Caserta beckons with new experiences!

When you’re ready for some sightseeing, make your way to Palace Of Caserta. This much-appreciated mountain park is rated 4.6 out of 5 stars in 36,840 reviews. Each year, 296,577 people visit this site to admire its unique features.

Next up is Giardini Reali - Parco Reggia Di Caserta. This sightseeing destination has an average rating of 4.7 out of 5 stars from 18,740 visitors.

At the end of the day, you will drive to L'aquila, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in L'aquila. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Discover the culinary delights of L'aquila by securing a reservation at FØRMA contemporary restaurant. Esteemed for its a Bib Gourmand award, this restaurant offers a remarkable selection of contemporary, and creative cuisine. Alternatively, DECA beckons with its unique menu offerings.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Art Cafè L'aquila stands out as an excellent choice for a post-dinner cocktail.

Celebrate another amazing day of your road trip adventure in Italy!

On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Santa Maria degli Angeli, and Perugia. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.

Santa Maria degli Angeli’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of L'aquila behind. This drive usually takes around 2 hours 23 min. Santa Maria degli Angeli welcomes you with a multitude of unique vacation experiences.

When you’re ready for some sightseeing, make your way to Basilica Of San Francesco D'assisi. This much-appreciated papal basilica is rated 4.9 out of 5 stars in 33,258 reviews.

When you’ve had your share of Santa Maria degli Angeli, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Santa Maria degli Angeli. Your travel time is around 9 min.

When you're ready to see some sights, Basilica Of Santa Maria Degli Angeli is a great place to start. This papal basilica is rated an average of 4.8 out of 5 stars by 19,258 visitors.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of your accommodation in Perugia. Perugia offers plenty of top-rated hotels and other places to stay on any travel budget. Take some time to relax before you head out to explore.

After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.

Treat yourself to a wonderful meal at Ristorante Settimo Sigillo, a top-rated dining spot in Perugia. If you're in the mood for something new, try Bar Pellas, another premier location with a delectable menu. You might also want to book a table at La Taverna. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Perugia.

Continue your evening by exploring the vibrant nightlife scene at Tommi Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Valentina, a bar that offers unique local touches. Likewise, Caffe Dal Perugino provides an excellent alternative for a fun evening.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 11 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Siena. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Florence. You will spend 1 night here for some well-deserved relaxation.

Set your GPS to Siena and hit the road. Expect a journey of approximately 1 hour 23 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Siena beckons with new experiences!

Be one of the day’s first visitors at Piazza Del Campo. This square is rated an average of 4.8 out of 5 stars by 64,175 visitors.

When you’re finished at Piazza Del Campo, head to Pubblico Palace. This one-of-a-kind museum is rated an average of 4.7 out of 5 stars in 1,400 reviews.

Beyond the above-mentioned attractions, you also have the opportunity to visit Siena Cathedral. This domus is rated an average of 4.8 out of 5 stars by 21,656 visitors.

If you’re keen to explore more, then consider a visit to Fortezza Medicea (siena). This fortress is a much-appreciated attraction with an average rating of 4.5 out of 5 stars from 9,835 visitors.

When you’re done exploring for the day, you’ll drive to Florence, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Experience a symphony of flavors at Enoteca Pinchiorri in Florence by securing a reservation in advance. Renowned for its 3-star Michelin distinction, Enoteca Pinchiorri delights its guests with its exceptional variety of meals showcasing delicious italian contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Santa Elisabetta, acclaimed for its delectable creative, and mediterranean specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Gucci Osteria da Massimo Bottura, a top-rated restaurant known for its outstanding menu. Known as a top-rated 1-star Michelin establishment, it's a top choice for italian contemporary, and international cuisine in the city.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

Embark on another extraordinary experience on day 12 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Florence. At the end of the day, you will enjoy the comforts of a top-rated hotel in Pisa, which will be your home away from home for 1 night.

Your sightseeing of the day begins at Piazza Della Signoria, a remarkable square where it’s easy to get lost in exploration. This top attraction is rated an average of 4.8 out of 5 stars in 66,956 reviews.

Next, satisfy your wanderlust at Cathedral Of Santa Maria Del Fiore. This church has an average rating of 4.8 out of 5 stars from 76,359 travelers.

Ponte Vecchio is another must-visit attraction. This renowned deck arch bridge offers a memorable experience, well worth a stop on your self-guided sightseeing tour. Rated 4.7 out of 5 stars by 118,099 travelers, it's one of the more popular places to see in the area.

Beyond the above-mentioned sites, you also have the opportunity to visit Uffizi Gallery. This well-loved national museum boasts a 4.7 out of 5-star rating from 61,794 reviews. In a single year, approximately 2,011,219 visitors add this sightseeing spot to their travel itineraries.

When there’s still energy left for exploring, Piazzale Michelangelo awaits. If you’ve been interested in experiencing a square, this is a top pick rated 4.8 out of 5 stars by 77,744 previous visitors.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Pisa's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Ristorante alle Bandierine, a top-rated dining destination in Pisa. If you're in the mood to try something new, consider Barrique Cocktail And Bistrot, another top spot with a mouthwatering menu. You might also want to secure a reservation at Filter Coffee Lab. With a reputation for consistently satisfied customers, it’s a perfect choice to enhance your stay in Pisa this evening.

Continue the enjoyment post-dinner at Bar Mocambo, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Tree offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Chupiteria. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Italy!